Published in J Biol Chem on August 27, 1999
Exercise-induced oxidative stress: cellular mechanisms and impact on muscle force production. Physiol Rev (2008) 5.74
Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean? Br J Pharmacol (2004) 5.29
Effect of regulated expression of human cyclooxygenase isoforms on eicosanoid and isoeicosanoid production in inflammation. J Clin Invest (2000) 1.78
Alcohol-induced generation of lipid peroxidation products in humans. J Clin Invest (1999) 1.55
Unorthodox routes to prostanoid formation: new twists in cyclooxygenase-initiated pathways. J Clin Invest (2001) 1.49
Quantitative high performance liquid chromatography/tandem mass spectrometric analysis of the four classes of F(2)-isoprostanes in human urine. Proc Natl Acad Sci U S A (1999) 1.45
The protective effect of amiodarone in lung tissue of cecal ligation and puncture-induced septic rats: a perspective from inflammatory cytokine release and oxidative stress. Naunyn Schmiedebergs Arch Pharmacol (2013) 1.41
Effects of chronic and acute ozone exposure on lipid peroxidation and antioxidant capacity in healthy young adults. Environ Health Perspect (2007) 1.36
Systemic elevations of free radical oxidation products of arachidonic acid are associated with angiographic evidence of coronary artery disease. Free Radic Biol Med (2006) 1.33
Oxidative stress, insulin resistance, dyslipidemia and type 2 diabetes mellitus. World J Diabetes (2015) 1.33
Genetic polymorphisms in the oxidative stress pathway and susceptibility to non-Hodgkin lymphoma. Hum Genet (2006) 1.24
HDL, lipid peroxidation, and atherosclerosis. J Lipid Res (2009) 1.22
Human tear lipocalin acts as an oxidative-stress-induced scavenger of potentially harmful lipid peroxidation products in a cell culture system. Biochem J (2001) 1.18
Evaluating oxidative stress in human cardiovascular disease: methodological aspects and considerations. Curr Med Chem (2012) 1.15
Reactive oxygen species: impact on skeletal muscle. Compr Physiol (2011) 1.14
Reduction in hypericin-induced phototoxicity by Hypericum perforatum extracts and pure compounds. J Photochem Photobiol B (2006) 1.07
Atherosclerosis and osteoporosis: age-dependent degenerative processes or related entities? Osteoporos Int (2008) 1.06
Membrane-mediated amyloidogenesis and the promotion of oxidative lipid damage by amyloid beta proteins. J Biol Chem (2007) 1.01
Women and smokers have elevated urinary F(2)-isoprostane metabolites: a novel extraction and LC-MS methodology. Lipids (2008) 1.00
Punicic acid a conjugated linolenic acid inhibits TNFalpha-induced neutrophil hyperactivation and protects from experimental colon inflammation in rats. PLoS One (2009) 0.99
Novel eicosapentaenoic acid-derived F3-isoprostanes as biomarkers of lipid peroxidation. J Biol Chem (2009) 0.97
Cystic fibrosis-related diabetes: from CFTR dysfunction to oxidative stress. Clin Biochem Rev (2009) 0.96
Analysis of oxidative stress and wound-inducible dinor isoprostanes F(1) (phytoprostanes F(1)) in plants. Plant Physiol (2000) 0.96
Bioactive products formed in humans from fish oils. J Lipid Res (2015) 0.95
Tempol attenuates the exercise pressor reflex independently of neutralizing reactive oxygen species in femoral artery ligated rats. J Appl Physiol (1985) (2011) 0.93
Urine metabolites reflect time-dependent effects of cyclosporine and sirolimus on rat kidney function. Chem Res Toxicol (2009) 0.90
Biomarkers of oxidative stress study V: ozone exposure of rats and its effect on lipids, proteins, and DNA in plasma and urine. Free Radic Biol Med (2013) 0.89
Increased oxidative stress in patients with depression and its relationship to treatment. Psychiatry Res (2012) 0.88
Eicosapentaenoic-acid-derived isoprostanes: synthesis and discovery of two major isoprostanes. Bioorg Med Chem Lett (2008) 0.86
Failure to consider the menstrual cycle phase may cause misinterpretation of clinical and research findings of cardiometabolic biomarkers in premenopausal women. Epidemiol Rev (2013) 0.84
Relationship of urinary isoprostanes to prostate cancer occurrence. Mol Cell Biochem (2012) 0.84
Enhanced production of nitric oxide, reactive oxygen species, and pro-inflammatory cytokines in very long chain saturated fatty acid-accumulated macrophages. Lipids Health Dis (2008) 0.83
Oxidative stress in fibromyalgia and its relationship to symptoms. Clin Rheumatol (2008) 0.83
An Evaluation of the Clinical Evidence on the Role of Inflammation and Oxidative Stress in Smoking-Mediated Cardiovascular Disease. Biomark Insights (2008) 0.83
Pathophysiology of isoprostanes in the cardiovascular system: implications of isoprostane-mediated thromboxane A2 receptor activation. Br J Pharmacol (2014) 0.82
Seminal plasma levels of 15-F2α-isoprostane, malondialdehyde and total homocysteine in normozoospermic and asthenozoospermic males. Indian J Clin Biochem (2005) 0.80
Generation of 8-epi-prostaglandin F(2alpha) in isolated rat kidney glomeruli by a radical-independent mechanism. Br J Pharmacol (2001) 0.79
F(2)-isoprostanes as novel biomarkers for type 2 diabetes: a review. J Clin Biochem Nutr (2009) 0.79
Application of medical and analytical methods in Lyme borreliosis monitoring. Anal Bioanal Chem (2011) 0.78
Can urinary excretion rate of 8-isoprostrane and malonaldehyde predict postoperative cognitive dysfunction in aging? Neurol Sci (2013) 0.77
Differences between basal lung levels of select eicosanoids in rat and mouse. Pulm Circ (2013) 0.77
Improved method of plasma 8-Isoprostane measurement and association analyses with habitual drinking and smoking. World J Gastroenterol (2006) 0.77
A new approach to the synthesis of polyunsaturated deuterated isoprostanes: total synthesis of d4-5-epi-8,12-iso-iPF3alpha-VI and d4-8,12-iso-iPF3alpha-VI. Bioorg Med Chem Lett (2009) 0.76
Beneficial effects of acute inhibition of the oxidative pentose phosphate pathway in the failing heart. Am J Physiol Heart Circ Physiol (2014) 0.76
Mycophenolate mofetil enhances the negative effects of sirolimus and tacrolimus on rat kidney cell metabolism. PLoS One (2014) 0.75
Oxidative profile exhibited by Mucopolysaccharidosis type IVA patients at diagnosis: Increased keratan urinary levels. Mol Genet Metab Rep (2017) 0.75
Nitric oxide-releasing agent, LA419, reduces atherogenesis in apolipoprotein E-deficient mice. Naunyn Schmiedebergs Arch Pharmacol (2008) 0.75
Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials. Lancet (2013) 8.16
Cyclooxygenase inhibitors and the antiplatelet effects of aspirin. N Engl J Med (2001) 5.96
Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. Proc Natl Acad Sci U S A (1999) 4.16
Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning? Free Radic Biol Med (2005) 3.13
Platelet activation in unstable coronary disease. N Engl J Med (1986) 2.60
Regulation of CLOCK and MOP4 by nuclear hormone receptors in the vasculature: a humoral mechanism to reset a peripheral clock. Cell (2001) 2.59
Effects of vitamin E on lipid peroxidation in healthy persons. JAMA (2001) 2.58
The antihypertensive effects of fish oil. A controlled study of polyunsaturated fatty acid supplements in essential hypertension. N Engl J Med (1989) 2.36
No evidence for lipid peroxidation in severe preeclampsia. Am J Obstet Gynecol (2001) 2.28
Platelet-active drugs : the relationships among dose, effectiveness, and side effects. Chest (2001) 2.25
Genetic and pharmacological analysis of prostanoid receptor function. J Clin Invest (2001) 2.19
Estimated rate of prostacyclin secretion into the circulation of normal man. J Clin Invest (1981) 2.18
Endogenous biosynthesis of prostacyclin and thromboxane and platelet function during chronic administration of aspirin in man. J Clin Invest (1983) 2.13
Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids. J Pharmacol Exp Ther (1999) 2.10
Dose-related kinetics of aspirin. Presystemic acetylation of platelet cyclooxygenase. N Engl J Med (1984) 2.00
Vitamin E suppresses isoprostane generation in vivo and reduces atherosclerosis in ApoE-deficient mice. Nat Med (1998) 1.98
Inhibition of thromboxane formation in vivo and ex vivo: implications for therapy with platelet inhibitory drugs. Blood (1987) 1.96
Transcellular activation of platelets and endothelial cells by bioactive lipids in platelet microparticles. J Clin Invest (1997) 1.90
Increased F2-isoprostanes in Alzheimer's disease: evidence for enhanced lipid peroxidation in vivo. FASEB J (1998) 1.89
Increased formation of distinct F2 isoprostanes in hypercholesterolemia. Circulation (1999) 1.79
Increased 8,12-iso-iPF2alpha-VI in Alzheimer's disease: correlation of a noninvasive index of lipid peroxidation with disease severity. Ann Neurol (2000) 1.79
Effect of regulated expression of human cyclooxygenase isoforms on eicosanoid and isoeicosanoid production in inflammation. J Clin Invest (2000) 1.78
Combined administration of aspirin and a specific thrombin inhibitor in man. Circulation (1991) 1.74
Modulation of oxidant stress in vivo in chronic cigarette smokers. Circulation (1996) 1.74
Analysis of prostacyclin and thromboxane biosynthesis in cardiovascular disease. Circulation (1983) 1.73
Increased prostacyclin biosynthesis in patients with severe atherosclerosis and platelet activation. N Engl J Med (1984) 1.73
Modulation of monocyte-endothelial cell interactions by platelet microparticles. J Clin Invest (1998) 1.73
Angioplasty increases coronary sinus F2-isoprostane formation: evidence for in vivo oxidative stress during PTCA. J Am Coll Cardiol (2001) 1.71
A double blind placebo controlled crossover study of prostacyclin in man. Life Sci (1979) 1.67
Enhanced brain levels of 8,12-iso-iPF2alpha-VI differentiate AD from frontotemporal dementia. Neurology (2003) 1.66
Cloning and expression of a cDNA for the human prostaglandin E receptor EP1 subtype. J Biol Chem (1993) 1.59
Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor. Blood (2001) 1.59
Suppression of thromboxane A2 but not of systemic prostacyclin by controlled-release aspirin. N Engl J Med (1991) 1.58
Thromboxane A2 synthesis in pregnancy-induced hypertension. Lancet (1990) 1.56
Alcohol-induced generation of lipid peroxidation products in humans. J Clin Invest (1999) 1.55
Platelet activation by superoxide anion and hydroxyl radicals intrinsically generated by platelets that had undergone anoxia and then reoxygenated. Circulation (1997) 1.54
Isoprostanes: potential markers of oxidant stress in atherothrombotic disease. Arterioscler Thromb Vasc Biol (1997) 1.53
Measuring leukotrienes of slow reacting substance of anaphylaxis: development of a specific radioimmunoassay. J Immunol (1983) 1.53
Two polymorphisms in the human lipoprotein lipase (LPL) gene. Nucleic Acids Res (1987) 1.51
Marked platelet activation in vivo after intravenous streptokinase in patients with acute myocardial infarction. Circulation (1988) 1.49
Indices of lipid peroxidation in vivo: strengths and limitations. Free Radic Biol Med (2000) 1.48
Dipyridamole. N Engl J Med (1987) 1.48
Arachidonic acid metabolism in purified human lung mast cells. J Immunol (1984) 1.47
Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein e-deficient mice. Circulation (2001) 1.46
Effects of celecoxib on major prostaglandins in asthma. Clin Exp Allergy (2010) 1.45
Quantitative high performance liquid chromatography/tandem mass spectrometric analysis of the four classes of F(2)-isoprostanes in human urine. Proc Natl Acad Sci U S A (1999) 1.45
Clinical implications of prostaglandin and thromboxane A2 formation (1). N Engl J Med (1988) 1.45
IPF2alpha-I: an index of lipid peroxidation in humans. Proc Natl Acad Sci U S A (1998) 1.43
Biomarkers of oxidative stress study III. Effects of the nonsteroidal anti-inflammatory agents indomethacin and meclofenamic acid on measurements of oxidative products of lipids in CCl4 poisoning. Free Radic Biol Med (2005) 1.42
8-epi PGF2 alpha generation during coronary reperfusion. A potential quantitative marker of oxidant stress in vivo. Circulation (1997) 1.41
Confusion in reperfusion. Problems in the clinical development of antithrombotic drugs. Circulation (1997) 1.38
Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice. Proc Natl Acad Sci U S A (2001) 1.38
Inhibition of eicosanoid biosynthesis by glucocorticoids in humans. Proc Natl Acad Sci U S A (1990) 1.38
Localization of distinct F2-isoprostanes in human atherosclerotic lesions. J Clin Invest (1997) 1.38
Ablation of cyclooxygenase-2 in forebrain neurons is neuroprotective and dampens brain inflammation after status epilepticus. J Neurosci (2011) 1.37
In vivo indexes of platelet and vascular function during fish-oil administration in patients with atherosclerosis. N Engl J Med (1986) 1.36
11-Dehydrothromboxane B2: a quantitative index of thromboxane A2 formation in the human circulation. Proc Natl Acad Sci U S A (1986) 1.35
Activation of the murine EP3 receptor for PGE2 inhibits cAMP production and promotes platelet aggregation. J Clin Invest (2001) 1.29
The response to thromboxane A2 analogues in human platelets. Discrimination of two binding sites linked to distinct effector systems. J Biol Chem (1990) 1.29
The isoprostanes in biology and medicine. Trends Endocrinol Metab (2001) 1.29
Cyclooxygenase-dependent formation of the isoprostane, 8-epi prostaglandin F2 alpha. J Biol Chem (1995) 1.28
Biochemical evidence of a chronic abnormality in platelet and vascular function in healthy individuals who smoke cigarettes. Circulation (1987) 1.27
Distinct roles of prostaglandin H synthases 1 and 2 in T-cell development. J Clin Invest (1999) 1.25
Increased formation of the isoprostanes IPF2alpha-I and 8-epi-prostaglandin F2alpha in acute coronary angioplasty: evidence for oxidant stress during coronary reperfusion in humans. Circulation (1997) 1.23
Reduction of isoprostanes and regression of advanced atherosclerosis by apolipoprotein E. J Biol Chem (2001) 1.23
Eicosanoid forming enzyme mRNA in human tissues. Analysis by quantitative polymerase chain reaction. J Biol Chem (1991) 1.22
Endogenous prostacyclin biosynthesis and platelet function during selective inhibition of thromboxane synthase in man. J Clin Invest (1983) 1.21
Arachidonic acid in platelet microparticles up-regulates cyclooxygenase-2-dependent prostaglandin formation via a protein kinase C/mitogen-activated protein kinase-dependent pathway. J Biol Chem (1999) 1.21
Cardiovascular responses to the isoprostanes iPF(2alpha)-III and iPE(2)-III are mediated via the thromboxane A(2) receptor in vivo. Circulation (2000) 1.21
Clinical implications of prostaglandin and thromboxane A2 formation (2). N Engl J Med (1988) 1.19
Molecular cloning, primary structure, and expression of the human platelet/erythroleukemia cell 12-lipoxygenase. Proc Natl Acad Sci U S A (1990) 1.19
Endogenous biosynthesis of arachidonic acid epoxides in humans: increased formation in pregnancy-induced hypertension. Proc Natl Acad Sci U S A (1990) 1.17
Nomenclature of isoprostanes: a proposal. Prostaglandins (1997) 1.17
Paired analysis of urinary thromboxane B2 metabolites in humans. Thromb Res (1987) 1.15
Estimated rate of thromboxane secretion into the circulation of normal humans. J Clin Invest (1986) 1.15
Prostaglandin F2alpha (PGF2alpha) and the isoprostane, 8, 12-iso-isoprostane F2alpha-III, induce cardiomyocyte hypertrophy. Differential activation of downstream signaling pathways. J Biol Chem (1998) 1.14
Simply read: erythrocytes modulate platelet function. Should we rethink the way we give aspirin? Circulation (1997) 1.13
Thromboxane A2 in vasotonic angina pectoris: evidence from direct measurements and inhibitor trials. N Engl J Med (1981) 1.12
Thromboxane A2 biosynthesis in human disease. Fed Proc (1987) 1.11
The development of sensitive and specific radioimmunoassays for leukotrienes. Prostaglandins Leukot Med (1984) 1.11
Local amplification of platelet function by 8-Epi prostaglandin F2alpha is not mediated by thromboxane receptor isoforms. J Biol Chem (1996) 1.10
Decreased prostacyclin biosynthesis preceding the clinical manifestation of pregnancy-induced hypertension. Circulation (1987) 1.08
Urinary leukotriene E4 levels during early and late asthmatic responses. J Allergy Clin Immunol (1990) 1.07
Phosphorylation of the thromboxane receptor alpha, the predominant isoform expressed in human platelets. J Biol Chem (1999) 1.07
The biochemical pharmacology of thromboxane synthase inhibition in man. Circulation (1985) 1.05
Generation of 8-epiprostaglandin F2alpha by human monocytes. Discriminate production by reactive oxygen species and prostaglandin endoperoxide synthase-2. J Biol Chem (1996) 1.05
Endogenous biosynthesis of prostacyclin during cardiac catheterization and angiography in man. Circulation (1985) 1.05
Influence of hospitalization and placebo therapy on blood pressure and sympathetic function in essential hypertension. Hypertension (1981) 1.04
Endogenous biosynthesis of thromboxane and prostacyclin in 2 distinct murine models of atherosclerosis. Blood (2000) 1.02