Published in J Immunol on September 15, 1999
Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis. J Clin Invest (2006) 4.41
Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis. J Cell Biol (2000) 3.63
High PKC alpha and low E-cadherin expression contribute to high migratory activity of colon carcinoma cells. Mol Biol Cell (2001) 1.23
A role for PKC-epsilon in Fc gammaR-mediated phagocytosis by RAW 264.7 cells. J Cell Biol (2002) 1.12
Phosphorylation of pleckstrin increases proinflammatory cytokine secretion by mononuclear phagocytes in diabetes mellitus. J Immunol (2007) 0.98
Loss of pleckstrin defines a novel pathway for PKC-mediated exocytosis. Blood (2009) 0.96
Activation of protein kinase C beta II by the stereo-specific phosphatidylserine receptor is required for phagocytosis of apoptotic thymocytes by resident murine tissue macrophages. J Biol Chem (2002) 0.90
Disturbances in metabolic, transport and structural genes in experimental colonic inflammation in the rat: a longitudinal genomic analysis. BMC Genomics (2008) 0.88
Transcriptome analysis reveals mucin 4 to be highly associated with periodontitis and identifies pleckstrin as a link to systemic diseases. Sci Rep (2015) 0.82
Localized diacylglycerol-dependent stimulation of Ras and Rap1 during phagocytosis. J Biol Chem (2009) 0.82
Gene expression versus sequence for predicting function: Glia Maturation Factor gamma is not a glia maturation factor. Genomics Proteomics Bioinformatics (2003) 0.80
Proteomic profiling of lipopolysaccharide-activated macrophages by isotope coded affinity tagging. J Proteome Res (2010) 0.79
Crystallization and preliminary diffraction analysis of truncated human pleckstrin. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.76
Systematic genetic analysis with ordered arrays of yeast deletion mutants. Science (2001) 24.48
Antibodies to major histocompatibility antigens produced by hybrid cell lines. Nature (1977) 16.54
Cellular responses to interferon-gamma. Annu Rev Immunol (1997) 13.23
Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles. Science (2000) 13.20
F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex. Cell (1997) 11.62
Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication. Nature (2001) 7.31
The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation. Mol Cell (1998) 6.20
Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis. Trends Genet (1998) 4.90
Mechanisms that help the yeast cell cycle clock tick: G2 cyclins transcriptionally activate G2 cyclins and repress G1 cyclins. Cell (1993) 4.75
Efficacy and safety of lidocaine-prilocaine cream for pain during circumcision. N Engl J Med (1997) 4.37
Concentration of viruses from sewage and excreta on insoluble polyelectrolytes. Appl Microbiol (1969) 4.17
Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway. Cell (1996) 4.06
Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast. Genes Dev (1998) 3.91
The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27. Nat Cell Biol (2001) 3.87
Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis. J Cell Biol (2000) 3.63
Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation. J Cell Biol (2001) 3.63
Identification of marrow-derived and thymus-derived small lymphocytes in the lymphoid tissue and thoracic duct lymph of normal rats. J Exp Med (1972) 3.54
The life-span and recirculation of marrow-derived small lymphocytes from the rat thoracic duct. J Exp Med (1972) 3.42
The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange. Nature (1998) 3.41
Virus isolations from sewage and from a stream receiving effluents of sewage treatment plants. Bull World Health Organ (1970) 3.27
MHC class II region encoding proteins related to the multidrug resistance family of transmembrane transporters. Nature (1991) 2.94
Conformational maturation of CFTR but not its mutant counterpart (delta F508) occurs in the endoplasmic reticulum and requires ATP. EMBO J (1994) 2.93
Role of antibody and complement in the immune clearance and destruction of erythrocytes. I. In vivo effects of IgG and IgM complement-fixing sites. J Clin Invest (1972) 2.82
Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes. J Exp Med (1999) 2.81
Mechanisms of regulation of the Na+/H+ exchanger. J Membr Biol (1986) 2.72
Isolation and characterization of cDNA clones encoding a functional p34cdc2 homologue from Zea mays. Proc Natl Acad Sci U S A (1991) 2.72
Inhibition of G1 cyclin activity by the Ras/cAMP pathway in yeast. Nature (1994) 2.71
The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells. J Biol Chem (1993) 2.65
Effect of polymorphism of an MHC-linked transporter on the peptides assembled in a class I molecule. Nature (1992) 2.61
The PCL2 (ORFD)-PHO85 cyclin-dependent kinase complex: a cell cycle regulator in yeast. Science (1994) 2.41
Regulation of the mating pheromone and invasive growth responses in yeast by two MAP kinase substrates. Curr Biol (1997) 2.32
Natural resistance to intracellular infections: natural resistance-associated macrophage protein 1 (Nramp1) functions as a pH-dependent manganese transporter at the phagosomal membrane. J Exp Med (2000) 2.28
Restricted accumulation of phosphatidylinositol 3-kinase products in a plasmalemmal subdomain during Fc gamma receptor-mediated phagocytosis. J Cell Biol (2001) 2.28
Two families of GTPases dominate the complex cellular response to IFN-gamma. J Immunol (1998) 2.27
Cytoplasmic pH regulation in thymic lymphocytes by an amiloride-sensitive Na+/H+ antiport. J Gen Physiol (1984) 2.23
Calreticulin is essential for integrin-mediated calcium signalling and cell adhesion. Nature (1997) 2.21
Na+/H+ exchangers of mammalian cells. J Biol Chem (1997) 2.12
Focal exocytosis of VAMP3-containing vesicles at sites of phagosome formation. J Cell Biol (2000) 2.10
The Syk protein tyrosine kinase is essential for Fcgamma receptor signaling in macrophages and neutrophils. Mol Cell Biol (1998) 2.10
Phosphatidylinositol polyphosphate binding to the mammalian septin H5 is modulated by GTP. Curr Biol (2000) 2.09
Fission yeast Clp1p phosphatase regulates G2/M transition and coordination of cytokinesis with cell cycle progression. Curr Biol (2001) 2.04
The molecular dissection of Fc gamma receptor mediated phagocytosis. Blood (1995) 2.02
Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30 )complex. EMBO J (2000) 2.02
Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter. Nature (1992) 2.01
Specific positive selection of lymphocytes reactive to strong histocompatibility antigens. J Exp Med (1974) 1.98
The F-box: a new motif for ubiquitin dependent proteolysis in cell cycle regulation and signal transduction. Prog Biophys Mol Biol (1999) 1.98
Phagosomal acidification is mediated by a vacuolar-type H(+)-ATPase in murine macrophages. J Biol Chem (1990) 1.94
Selectivity of MHC-encoded peptide transporters from human, mouse and rat. Nature (1994) 1.88
Effect of corticosteroids on the human monocyte IgG and complement receptors. J Clin Invest (1975) 1.88
A precision measurement of the mass of the top quark. Nature (2004) 1.87
Harvesting the genome's bounty: integrative genomics. Cold Spring Harb Symp Quant Biol (2003) 1.84
Hemolytic uremic syndrome and diarrhea in Argentine children: the role of Shiga-like toxins. J Infect Dis (1989) 1.82
Role of antibody and complement in the immune clearance and destruction of erythrocytes. II. Molecular nature of IgG and IgM complement-fixing sites and effects of their interaction with serum. J Clin Invest (1972) 1.82
Mechanism of acidification of the trans-Golgi network (TGN). In situ measurements of pH using retrieval of TGN38 and furin from the cell surface. J Biol Chem (1998) 1.78
Volume-induced increase of anion permeability in human lymphocytes. J Gen Physiol (1982) 1.78
Proteasome subunits encoded by the major histocompatibility complex are not essential for antigen presentation. Nature (1992) 1.76
The role of the human Fc receptor Fc gamma RIIA in the immune clearance of platelets: a transgenic mouse model. J Immunol (1999) 1.75
The origin of antibody forming cells from lymphocytes. Antibiot Chemother (1969) 1.75
Caffeine and halothane sensitivity of intracellular Ca2+ release is altered by 15 calcium release channel (ryanodine receptor) mutations associated with malignant hyperthermia and/or central core disease. J Biol Chem (1997) 1.74
Transmembrane ion fluxes during activation of human T lymphocytes: role of Ca2+, Na+/H+ exchange and phospholipid turnover. Immunol Rev (1987) 1.74
Host resistance to intracellular infection: mutation of natural resistance-associated macrophage protein 1 (Nramp1) impairs phagosomal acidification. J Exp Med (1998) 1.73
A pH-sensitive and voltage-dependent proton conductance in the plasma membrane of macrophages. J Gen Physiol (1993) 1.71
Rho is required for the initiation of calcium signaling and phagocytosis by Fcgamma receptors in macrophages. J Exp Med (1997) 1.71
Impaired function of macrophage Fc gamma receptors in end-stage renal disease. N Engl J Med (1990) 1.70
Responses of lymphocytes to anisotonic media: volume-regulating behavior. Am J Physiol (1984) 1.69
Cytoplasmic pH regulation in phorbol ester-activated human neutrophils. Am J Physiol (1986) 1.68
Inhibition by C1INH of Hagemann factor fragment activation of coagulation, fibrinolysis, and kinin generation. J Clin Invest (1973) 1.68
Monoclonal antibodies as tools to analyze the serological and genetic complexities of major transplantation antigens. Immunol Rev (1979) 1.67
Dynamic measurement of the pH of the Golgi complex in living cells using retrograde transport of the verotoxin receptor. J Cell Biol (1996) 1.67
Phagosomal maturation, acidification, and inhibition of bacterial growth in nonphagocytic cells transfected with FcgammaRIIA receptors. J Biol Chem (1999) 1.63
Deletion of the Cul1 gene in mice causes arrest in early embryogenesis and accumulation of cyclin E. Curr Biol (1999) 1.63
SCF ubiquitin protein ligases and phosphorylation-dependent proteolysis. Philos Trans R Soc Lond B Biol Sci (1999) 1.62
Protected environments and prophylactic antibiotics. A prospective controlled study of their utility in the therapy of acute leukemia. N Engl J Med (1973) 1.61
Human Fc gamma RII, in the absence of other Fc gamma receptors, mediates a phagocytic signal. J Clin Invest (1991) 1.60
Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60
Noninvasive measurement of the pH of the endoplasmic reticulum at rest and during calcium release. Proc Natl Acad Sci U S A (1998) 1.59
A new family of regulators of G-protein-coupled receptors? Curr Biol (1996) 1.58
Volume regulation by human lymphocytes. Role of calcium. J Gen Physiol (1982) 1.58
Luteal phase defect: the sensitivity and specificity of diagnostic methods in common clinical use. Fertil Steril (1994) 1.58
Functional characterization of three isoforms of the Na+/H+ exchanger stably expressed in Chinese hamster ovary cells. ATP dependence, osmotic sensitivity, and role in cell proliferation. J Biol Chem (1994) 1.57
Proton currents in human granulocytes: regulation by membrane potential and intracellular pH. J Physiol (1993) 1.56
Interaction of DNA with a porphyrin ligand: evidence for intercalation. Nucleic Acids Res (1979) 1.56
SCF(Met30)-mediated control of the transcriptional activator Met4 is required for the G(1)-S transition. EMBO J (2000) 1.55
Determinants of the phagosomal pH in macrophages. In situ assessment of vacuolar H(+)-ATPase activity, counterion conductance, and H+ "leak". J Biol Chem (1991) 1.54
Phorbol ester-induced actin assembly in neutrophils: role of protein kinase C. J Cell Biol (1992) 1.54
Plasma inhibitors of the components of the fibrinolytic pathway in man. J Clin Invest (1973) 1.53
The induction of augmented granulocyte adherence by inflammation. Mediation by a plasma factor. J Clin Invest (1976) 1.53
The iron transport protein NRAMP2 is an integral membrane glycoprotein that colocalizes with transferrin in recycling endosomes. J Exp Med (1999) 1.53
Regulation of phagosomal acidification. Differential targeting of Na+/H+ exchangers, Na+/K+-ATPases, and vacuolar-type H+-atpases. J Biol Chem (1997) 1.52
Intracellular pH regulation by Na(+)/H(+) exchange requires phosphatidylinositol 4,5-bisphosphate. J Cell Biol (2000) 1.52
A randomized clinical trial of granulocyte transfusions for infection in acute leukemia. N Engl J Med (1977) 1.51
Characterization of the activation of Na+/H+ exchange in lymphocytes by phorbol esters: change in cytoplasmic pH dependence of the antiport. Proc Natl Acad Sci U S A (1985) 1.50
MAPK specificity in the yeast pheromone response independent of transcriptional activation. Curr Biol (2001) 1.50
Immune thrombocytopenia. Use of a Coombs antiglobulin test to detect IgG and C3 on platelets. N Engl J Med (1979) 1.49
The identification of sera distinguishing marrow-derived and thymus-derived lymphocytes in the rat thoracic duct. Immunology (1974) 1.49