Structural features required for the interaction of the Hsp70 molecular chaperone DnaK with its cochaperone DnaJ.

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Tim14, a novel key component of the import motor of the TIM23 protein translocase of mitochondria. EMBO J (2003) 1.84

Nucleotide exchange factor for the yeast Hsp70 molecular chaperone Ssa1p. Mol Cell Biol (2002) 1.62

Allostery in the Hsp70 chaperone proteins. Top Curr Chem (2013) 1.52

Heat shock protein 70 kDa chaperone/DnaJ cochaperone complex employs an unusual dynamic interface. Proc Natl Acad Sci U S A (2011) 1.47

Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation. Nature (2015) 1.29

The 70-kDa heat shock protein chaperone nucleotide-binding domain in solution unveiled as a molecular machine that can reorient its functional subdomains. Proc Natl Acad Sci U S A (2004) 1.28

BiP mutants that are unable to interact with endoplasmic reticulum DnaJ proteins provide insights into interdomain interactions in BiP. Proc Natl Acad Sci U S A (2008) 1.15

The structural and functional diversity of Hsp70 proteins from Plasmodium falciparum. Protein Sci (2007) 1.09

A cytosolic chaperone complexes with dynamic membrane J-proteins and mobilizes a nonenveloped virus out of the endoplasmic reticulum. PLoS Pathog (2014) 1.02

Conserved, disordered C terminus of DnaK enhances cellular survival upon stress and DnaK in vitro chaperone activity. J Biol Chem (2011) 0.99

Metazoan Hsp70-based protein disaggregases: emergence and mechanisms. Front Mol Biosci (2015) 0.97

Analysis of sequence-specific binding of RNA to Hsp70 and its various homologs indicates the involvement of N- and C-terminal interactions. RNA (2001) 0.97

Analysis of the levels of conservation of the J domain among the various types of DnaJ-like proteins. Cell Stress Chaperones (2000) 0.97

Modeling Hsp70-mediated protein folding. Biophys J (2006) 0.95

Plasmodium falciparum heat shock protein 70 is able to suppress the thermosensitivity of an Escherichia coli DnaK mutant strain. Mol Genet Genomics (2005) 0.94

The Escherichia coli DjlA and CbpA proteins can substitute for DnaJ in DnaK-mediated protein disaggregation. J Bacteriol (2004) 0.90

J domain co-chaperone specificity defines the role of BiP during protein translocation. J Biol Chem (2010) 0.90

A functional DnaK dimer is essential for the efficient interaction with Hsp40 heat shock protein. J Biol Chem (2015) 0.89

The Hsp70 peptide-binding domain determines the interaction of the ATPase domain with Tim44 in mitochondria. EMBO J (2002) 0.88

Segmental isotopic labeling of the Hsp70 molecular chaperone DnaK using expressed protein ligation. Biopolymers (2010) 0.88

Curing of yeast [URE3] prion by the Hsp40 cochaperone Ydj1p is mediated by Hsp70. Genetics (2008) 0.88

Close and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiP. Structure (2015) 0.88

Experimentally biased model structure of the Hsc70/auxilin complex: substrate transfer and interdomain structural change. Protein Sci (2004) 0.85

Cytosolic and ER J-domains of mammalian and parasitic origin can functionally interact with DnaK. Int J Biochem Cell Biol (2006) 0.84

Multiple molecules of Hsc70 and a dimer of DjA1 independently bind to an unfolded protein. J Biol Chem (2010) 0.83

Zuotin, a DnaJ molecular chaperone, stimulates cap-independent translation in yeast. Biochem Biophys Res Commun (2006) 0.82

Characterization of Campylobacter jejuni RacRS reveals roles in the heat shock response, motility, and maintenance of cell length homogeneity. J Bacteriol (2012) 0.81

The lid domain of Caenorhabditis elegans Hsc70 influences ATP turnover, cofactor binding and protein folding activity. PLoS One (2012) 0.80

Antigenic peptides complexed to phylogenically diverse Hsp70s induce differential immune responses. Cell Stress Chaperones (2003) 0.79

Yeast prions are useful for studying protein chaperones and protein quality control. Prion (2015) 0.78

Species- and Strain-Specific Adaptation of the HSP70 Super Family in Pathogenic Trypanosomatids. Genome Biol Evol (2016) 0.77

Structural and Biological Interaction of hsc-70 Protein with Phosphatidylserine in Endosomal Microautophagy. J Biol Chem (2016) 0.76

Spatial localisation of chaperone distribution in the endoplasmic reticulum of yeast. IET Syst Biol (2012) 0.76

Tracking the interplay between bound peptide and the lid domain of DnaK, using molecular dynamics. Int J Mol Sci (2013) 0.76

Reconstitution of a Mycobacterium tuberculosis proteostasis network highlights essential cofactor interactions with chaperone DnaK. Proc Natl Acad Sci U S A (2016) 0.76

A disulfide-bonded DnaK dimer is maintained in an ATP-bound state. Cell Stress Chaperones (2016) 0.75

The remarkable multivalency of the Hsp70 chaperones. Cell Stress Chaperones (2017) 0.75

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The operon that encodes the sigma subunit of RNA polymerase also encodes ribosomal protein S21 and DNA primase in E. coli K12. Cell (1983) 5.73

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A gene regulating the heat shock response in Escherichia coli also affects proteolysis. Proc Natl Acad Sci U S A (1984) 4.00

Sigma 32 synthesis can regulate the synthesis of heat shock proteins in Escherichia coli. Genes Dev (1987) 3.79

rpoE, the gene encoding the second heat-shock sigma factor, sigma E, in Escherichia coli. EMBO J (1995) 3.59

The sigmaE-mediated response to extracytoplasmic stress in Escherichia coli is transduced by RseA and RseB, two negative regulators of sigmaE. Mol Microbiol (1997) 3.58

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Polypeptides containing highly conserved regions of transcription initiation factor sigma 70 exhibit specificity of binding to promoter DNA. Cell (1992) 3.27

Transcription from a heat-inducible promoter causes heat shock regulation of the sigma subunit of E. coli RNA polymerase. Cell (1984) 3.10

Escherichia coli heat shock gene mutants are defective in proteolysis. Genes Dev (1988) 2.99

SurA, a periplasmic protein with peptidyl-prolyl isomerase activity, participates in the assembly of outer membrane porins. Genes Dev (1996) 2.91

Characterization of the pleiotropic phenotypes of rifampin-resistant rpoB mutants of Escherichia coli. J Bacteriol (1989) 2.81

Interaction of the Hsp70 molecular chaperone, DnaK, with its cochaperone DnaJ. Proc Natl Acad Sci U S A (1998) 2.44

The Escherichia coli sigma(E)-dependent extracytoplasmic stress response is controlled by the regulated proteolysis of an anti-sigma factor. Genes Dev (1999) 2.44

Mu dX, a derivative of Mu d1 (lac Apr) which makes stable lacZ fusions at high temperature. J Bacteriol (1983) 2.36

DnaK and DnaJ heat shock proteins participate in protein export in Escherichia coli. Genes Dev (1992) 2.34

Amino-terminal amino acids modulate sigma-factor DNA-binding activity. Genes Dev (1993) 2.30

DnaK, DnaJ, and GrpE are required for flagellum synthesis in Escherichia coli. J Bacteriol (1992) 2.28

Stringent response in Escherichia coli induces expression of heat shock proteins. J Mol Biol (1985) 2.26

SigmaE is an essential sigma factor in Escherichia coli. J Bacteriol (1997) 2.18

The SurA periplasmic PPIase lacking its parvulin domains functions in vivo and has chaperone activity. EMBO J (2001) 2.12

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Termination efficiency at rho-dependent terminators depends on kinetic coupling between RNA polymerase and rho. Proc Natl Acad Sci U S A (1992) 2.01

The activity of sigma 32 is reduced under conditions of excess heat shock protein production in Escherichia coli. Genes Dev (1989) 1.90

Characterization of the termination phenotypes of rifampicin-resistant mutants. J Mol Biol (1988) 1.88

The interface of sigma with core RNA polymerase is extensive, conserved, and functionally specialized. Genes Dev (1999) 1.85

Mutations in the Ion gene of E. coli K12 phenotypically suppress a mutation in the sigma subunit of RNA polymerase. Cell (1983) 1.74

Translational regulation of sigma 32 synthesis: requirement for an internal control element. J Bacteriol (1991) 1.70

degS (hhoB) is an essential Escherichia coli gene whose indispensable function is to provide sigma (E) activity. Mol Microbiol (2001) 1.64

The response to extracytoplasmic stress in Escherichia coli is controlled by partially overlapping pathways. Genes Dev (1997) 1.57

Equilibrium and kinetic studies of Escherichia coli lac repressor-inducer interactions. J Mol Biol (1972) 1.57

Effects of the mutant sigma allele rpoD800 on the synthesis of specific macromolecular components of the Escherichia coli K12 cell. J Mol Biol (1984) 1.55

A coiled-coil from the RNA polymerase beta' subunit allosterically induces selective nontemplate strand binding by sigma(70). Cell (2001) 1.55

Effects of rifampicin resistant rpoB mutations on antitermination and interaction with nusA in Escherichia coli. J Mol Biol (1988) 1.46

RpoB8, a rifampicin-resistant termination-proficient RNA polymerase, has an increased Km for purine nucleotides during transcription elongation. J Biol Chem (1991) 1.44

Identification and characterization of an outer membrane protein, OmpX, in Escherichia coli that is homologous to a family of outer membrane proteins including Ail of Yersinia enterocolitica. J Bacteriol (1995) 1.42

A mutant sigma 32 with a small deletion in conserved region 3 of sigma has reduced affinity for core RNA polymerase. J Bacteriol (1992) 1.42

Ischemic intervals during warm blood cardioplegia in the canine heart evaluated by phosphorus 31-magnetic resonance spectroscopy. J Thorac Cardiovasc Surg (1997) 1.39

Partial loss of function mutations in DnaK, the Escherichia coli homologue of the 70-kDa heat shock proteins, affect highly conserved amino acids implicated in ATP binding and hydrolysis. Proc Natl Acad Sci U S A (1992) 1.31

Intermediates in the formation of the open complex by RNA polymerase holoenzyme containing the sigma factor sigma 32 at the groE promoter. J Mol Biol (1989) 1.28

Accumulation of secretory protein precursors in Escherichia coli induces the heat shock response. J Bacteriol (1993) 1.27

Marker rescue with plasmids bearing deletions in rpoD identifies a dispensable part of E. coli sigma factor. Mol Gen Genet (1983) 1.24

Mutations in the sigma subunit of E. coli RNA polymerase which affect positive control of transcription. Mol Gen Genet (1985) 1.21

Four contiguous amino acids define the target for streptolydigin resistance in the beta subunit of Escherichia coli RNA polymerase. J Biol Chem (1993) 1.21

Involvement of the DnaK-DnaJ-GrpE chaperone team in protein secretion in Escherichia coli. J Bacteriol (1996) 1.16

The sigma subunit of Escherichia coli RNA polymerase senses promoter spacing. Proc Natl Acad Sci U S A (1996) 1.13

Physiological effects of the fructose-1,6-diphosphate aldolase ts8 mutation on stable RNA synthesis in Escherichia coli. J Bacteriol (1991) 1.12

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Analysis of three DnaK mutant proteins suggests that progression through the ATPase cycle requires conformational changes. J Biol Chem (1995) 1.06

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The anti-initial transcribed sequence, a portable sequence that impedes promoter escape, requires sigma70 for function. J Biol Chem (2001) 0.98

Identifying interacting regions in the beta subunit of Escherichia coli RNA polymerase. J Mol Biol (1996) 0.96

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Three rpoBC mutations that suppress the termination defects of rho mutants also affect the functions of nusA mutants. Mol Gen Genet (1989) 0.94

Amino acid substitutions in the two largest subunits of Escherichia coli RNA polymerase that suppress a defective Rho termination factor affect different parts of the transcription complex. J Biol Chem (1996) 0.94

Altered chemical properties in three mutants of E. coli RNA polymerase sigma subunit. Mol Gen Genet (1979) 0.91

Mutations in rpoD, the gene encoding the sigma 70 subunit of Escherichia coli RNA polymerase, that increase expression of the lac operon in the absence of CAP-cAMP. J Mol Biol (1988) 0.88

The Escherichia coli ts8 mutation is an allele of fda, the gene encoding fructose-1,6-diphosphate aldolase. J Bacteriol (1991) 0.87

Mutations in rpoD that increase expression of genes in the mal regulon of Escherichia coli K-12. J Mol Biol (1988) 0.87

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Sigma domain structure: one down, one to go. Structure (1996) 0.85

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Self-mutilation of the eye. J Clin Psychiatry (1979) 0.77

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The 2000 Thomas Hunt Morgan Medal. Evelyn M. Witkin. Genetics (2001) 0.75

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