Published in Hepatology on November 01, 1999
Opposing roles of STAT1 and STAT3 in T cell-mediated hepatitis: regulation by SOCS. J Clin Invest (2002) 2.40
Hepatocyte death: a clear and present danger. Physiol Rev (2010) 2.18
Importance of Kupffer cells for T-cell-dependent liver injury in mice. Am J Pathol (2000) 1.42
Natural killer T cell dysfunction in CD39-null mice protects against concanavalin A-induced hepatitis. Hepatology (2008) 1.27
CCR5 deficiency drives enhanced natural killer cell trafficking to and activation within the liver in murine T cell-mediated hepatitis. Am J Pathol (2007) 1.15
Regulation of hepatocyte fate by interferon-γ. Cytokine Growth Factor Rev (2011) 1.13
Differential roles of JNK in ConA/GalN and ConA-induced liver injury in mice. Am J Pathol (2008) 1.03
The eukaryotic initiation factor 2 kinase GCN2 protects against hepatotoxicity during asparaginase treatment. Am J Physiol Endocrinol Metab (2013) 0.90
Experimental models of hepatotoxicity related to acute liver failure. Toxicol Appl Pharmacol (2015) 0.88
Questions and controversies: the role of necroptosis in liver disease. Cell Death Discov (2016) 0.88
Protective effects of cyclosporine A on T-cell dependent ConA-induced liver injury in Kunming mice. World J Gastroenterol (2001) 0.87
Modulation of liver tolerance by conventional and nonconventional antigen-presenting cells and regulatory immune cells. Cell Mol Immunol (2016) 0.85
RIPK1 protects from TNF-α-mediated liver damage during hepatitis. Cell Death Dis (2016) 0.85
Opposite effects of high and low doses of interleukin-2 on T cell-mediated hepatitis in mice (interleukin-2 on hepatitis). Hepatol Int (2010) 0.84
Genetic delineation of the pathways mediated by bid and JNK in tumor necrosis factor-alpha-induced liver injury in adult and embryonic mice. J Biol Chem (2008) 0.84
Depletion of hepatic glutathione prevents death receptor-dependent apoptotic and necrotic liver injury in mice. Am J Pathol (2000) 0.81
Pretreatment with Fucoidan from Fucus vesiculosus Protected against ConA-Induced Acute Liver Injury by Inhibiting Both Intrinsic and Extrinsic Apoptosis. PLoS One (2016) 0.80
Substance P participates in immune-mediated hepatic injury induced by concanavalin A in mice and stimulates cytokine synthesis in Kupffer cells. Exp Ther Med (2013) 0.77
A murine model of NKT cell-mediated liver injury induced by alpha-galactosylceramide/d-galactosamine. Virchows Arch (2005) 0.77
A murder mystery in the liver: who done it and how? J Clin Invest (2016) 0.76
DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells. Cancer Res (2001) 5.45
A T cell-dependent experimental liver injury in mice inducible by concanavalin A. J Clin Invest (1992) 4.39
Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-alpha requires transcriptional arrest. J Immunol (1994) 2.87
Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models. Am J Pathol (1995) 2.55
Effect of filgrastim treatment on inflammatory cytokines and lymphocyte functions. Clin Pharmacol Ther (1999) 2.33
Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin A. Gastroenterology (1996) 2.27
Concanavalin A-induced T-cell-mediated hepatic injury in mice: the role of tumor necrosis factor. Hepatology (1995) 2.21
Glutathione peroxidase. Methods Enzymol (1981) 2.07
The refined structure of the selenoenzyme glutathione peroxidase at 0.2-nm resolution. Eur J Biochem (1983) 2.05
Tumor necrosis factor is a terminal mediator in galactosamine/endotoxin-induced hepatitis in mice. Biochem Pharmacol (1989) 1.87
Granulocyte colony-stimulating factor treatment protects rodents against lipopolysaccharide-induced toxicity via suppression of systemic tumor necrosis factor-alpha. J Immunol (1992) 1.60
In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis. Eur J Immunol (1997) 1.53
Effect of granulocyte colony-stimulating factor treatment on ex vivo blood cytokine response in human volunteers. Blood (1995) 1.52
A novel technique for selective NF-kappaB inhibition in Kupffer cells: contrary effects in fulminant hepatitis and ischaemia-reperfusion. Gut (2009) 1.49
The fate of extracellular glutathione in the rat. Biochim Biophys Acta (1978) 1.45
Activation of the 55 kDa TNF receptor is necessary and sufficient for TNF-induced liver failure, hepatocyte apoptosis, and nitrite release. J Immunol (1995) 1.45
Importance of Kupffer cells for T-cell-dependent liver injury in mice. Am J Pathol (2000) 1.42
Improved innate immunity of endotoxin-tolerant mice increases resistance to Salmonella enterica serovar typhimurium infection despite attenuated cytokine response. Infect Immun (2001) 1.40
SB1518, a novel macrocyclic pyrimidine-based JAK2 inhibitor for the treatment of myeloid and lymphoid malignancies. Leukemia (2011) 1.36
Hyperventilation induces release of cytokines from perfused mouse lung. Am J Respir Crit Care Med (1998) 1.36
A novel biologically active seleno-organic compound--II. Activity of PZ 51 in relation to glutathione peroxidase. Biochem Pharmacol (1984) 1.34
In vitro differentiation of human monocytes to macrophages: change of PDE profile and its relationship to suppression of tumour necrosis factor-alpha release by PDE inhibitors. Br J Pharmacol (1997) 1.34
The amino-acid sequence of bovine glutathione peroxidase. Hoppe Seylers Z Physiol Chem (1984) 1.31
Concanavalin A-induced liver cell damage: activation of intracellular pathways triggered by tumor necrosis factor in mice. Gastroenterology (1998) 1.28
Granulocyte-macrophage colony-stimulating factor and IFN-gamma restore the systemic TNF-alpha response to endotoxin in lipopolysaccharide-desensitized mice. J Immunol (1997) 1.26
Apoptosis in the absence of poly-(ADP-ribose) polymerase. Biochem Biophys Res Commun (1997) 1.25
The level and half-life of glutathione in human plasma. FEBS Lett (1980) 1.21
Acute paracetamol intoxication of starved mice leads to lipid peroxidation in vivo. Biochem Pharmacol (1979) 1.20
Selenium and drug metabolism--I. Multiple modulations of mouse liver enzymes. Biochem Pharmacol (1983) 1.18
The 55-kD tumor necrosis factor receptor and CD95 independently signal murine hepatocyte apoptosis and subsequent liver failure. Mol Med (1996) 1.16
Drug-induced lipid peroxidation in mice--I. Modulation by monooxygenase activity, glutathione and selenium status. Biochem Pharmacol (1981) 1.15
Acute hepatotoxicity of Pseudomonas aeruginosa exotoxin A in mice depends on T cells and TNF. J Immunol (1998) 1.13
Human monocytes express functional receptors for granulocyte colony-stimulating factor that mediate suppression of monokines and interferon-gamma. Blood (2000) 1.13
TNF-alpha-induced expression of adhesion molecules in the liver is under the control of TNFR1--relevance for concanavalin A-induced hepatitis. J Immunol (2001) 1.13
Lipopolysaccharide-induced interleukin-10 in mice: role of endogenous tumor necrosis factor-alpha. Eur J Immunol (1995) 1.13
Inducible nitric oxide synthase is critical for immune-mediated liver injury in mice. J Clin Invest (2001) 1.12
Role of sinusoidal endothelial cells of the liver in concanavalin A-induced hepatic injury in mice. Hepatology (1996) 1.12
[Carcinogenicity of glass fibers of different stability]. Zentralbl Hyg Umweltmed (1990) 1.11
[Glutathion peroxidase. I. Isolation and determinations of molecular weight]. Hoppe Seylers Z Physiol Chem (1971) 1.11
Metabolic depletion of ATP by fructose inversely controls CD95- and tumor necrosis factor receptor 1-mediated hepatic apoptosis. J Exp Med (2000) 1.11
DNA fragmentation in mouse organs during endotoxic shock. Am J Pathol (1996) 1.10
The multiple functions of heme oxygenase-1 in the liver. Z Gastroenterol (2012) 1.06
Tumor necrosis factor-induced apoptosis during the poisoning of mice with hepatotoxins. Gastroenterology (1997) 1.05
Structure analysis and molecular model of the selenoenzyme glutathione peroxidase at 2.8 A resolution. J Mol Biol (1979) 1.04
Tumor necrosis factor-induced hepatic DNA fragmentation as an early marker of T cell-dependent liver injury in mice. Gastroenterology (1995) 1.04
Selenoenzymes regulate the activity of leukocyte 5-lipoxygenase via the peroxide tone. J Biol Chem (1993) 1.03
Leukotriene-mediated liver injury. Biochem Pharmacol (1988) 1.03
Leukocyte alterations do not account for hepatitis induced by endotoxin or TNF alpha in galactosamine-sensitized mice. Biochem Pharmacol (1990) 1.02
ICE-protease inhibitors block murine liver injury and apoptosis caused by CD95 or by TNF-alpha. Immunol Lett (1997) 1.01
Control of fecal peritoneal infection in mice by colony-stimulating factors. J Infect Dis (1996) 1.00
Selenium and drug metabolism--III. Relation of glutathione-peroxidase and other hepatic enzyme modulations to dietary supplements. Biochem Pharmacol (1985) 1.00
Phospholipid hydroperoxide glutathione peroxidase in various mouse organs during selenium deficiency and repletion. Biochim Biophys Acta (1990) 1.00
The physiological consequences of glutathione variations. Life Sci (1992) 0.99
Pathophysiological mechanisms of TNF during intoxication with natural or man-made toxins. Toxicology (1999) 0.99
Concanavalin A-induced liver injury triggers hepatocyte proliferation. J Clin Invest (1998) 0.98
In vitro prevention and reversal of lipopolysaccharide desensitization by IFN-gamma, IL-12, and granulocyte-macrophage colony-stimulating factor. J Immunol (1997) 0.98
Selenium and drug metabolism--II. Independence of glutathione peroxidase and reversibility of hepatic enzyme modulations in deficient mice. Biochem Pharmacol (1984) 0.98
Cystic renal cell carcinoma is cured by resection: a study of 24 cases with long-term followup. J Urol (1999) 0.97
CD95-Mediated murine hepatic apoptosis requires an intact glutathione status. Hepatology (1999) 0.97
Phosphodiesterase profiles of highly purified human peripheral blood leukocyte populations from normal and atopic individuals: a comparative study. J Allergy Clin Immunol (1997) 0.96
Drug-induced lipid peroxidation in mice--II. Protection against paracetamol-induced liver necrosis by intravenous liposomally entrapped glutathione. Biochem Pharmacol (1982) 0.96
Comparative carcinogenicity of cigarette mainstream and sidestream smoke condensates on the mouse skin. J Cancer Res Clin Oncol (1990) 0.96
Modulation of cytokine release in ex vivo-stimulated blood from borreliosis patients. Infect Immun (2001) 0.95
Dissection of the intracellular pathways in hepatocytes suggests a role for Jun kinase and IFN regulatory factor-1 in Con A-induced liver failure. J Immunol (2001) 0.95
Prevention of endotoxin-induced lethality, but not of liver apoptosis in poly(ADP-ribose) polymerase-deficient mice. Biochem Biophys Res Commun (1999) 0.95
Potentiation by granulocyte macrophage colony-stimulating factor of lipopolysaccharide toxicity in mice. J Clin Invest (1994) 0.95
Novel pyrogen tests based on the human fever reaction. The report and recommendations of ECVAM Workshop 43. European Centre for the Validation of Alternative Methods. European Centre for the Validation of Alternative Methods. Altern Lab Anim (2001) 0.94
Cyclic nucleotide phosphodiesterases from purified human CD4+ and CD8+ T lymphocytes. Clin Exp Allergy (1995) 0.94
The activity of the peroxide-metabolizing system in human colon carcinoma. J Cancer Res Clin Oncol (1980) 0.94
Hydrocarbon exhalation. Methods Enzymol (1981) 0.94
Substrate-induced redox change of selenium in glutathione peroxidase studied by x-ray photoelectron spectroscopy. Biochim Biophys Acta (1975) 0.94
Cyclic nucleotide phosphodiesterase isoenzyme activities in human alveolar macrophages. Clin Exp Allergy (1995) 0.94
Inhibition of caspase activity prevents CD95-mediated hepatic microvascular perfusion failure and restores Kupffer cell clearance capacity. FASEB J (1999) 0.94
Low-molecular-weight hyaluronic acid induces nuclear factor-kappaB-dependent resistance against tumor necrosis factor alpha-mediated liver injury in mice. Hepatology (2001) 0.93
Effects of rSP-C surfactant on oxygenation and histology in a rat-lung-lavage model of acute lung injury. Am J Respir Crit Care Med (1998) 0.92
T cell stimulus-induced crosstalk between lymphocytes and liver macrophages results in augmented cytokine release. Exp Cell Res (1996) 0.92
Phosphodiesterase profile of human B lymphocytes from normal and atopic donors and the effects of PDE inhibition on B cell proliferation. Br J Pharmacol (1998) 0.92
Functional and fine structural changes in isolated rat lungs challenged with endotoxin ex vivo and in vitro. Am J Pathol (1995) 0.92
Ethane production by isolated perfused rat liver: a system to study metabolic effects related to lipid peroxidation. FEBS Lett (1981) 0.91
Temporal sequence of pulmonary and systemic inflammatory responses to graded polymicrobial peritonitis in mice. Infect Immun (1999) 0.91
A novel biologically active seleno-organic compound--V. Inhibition by ebselen (PZ 51) of rat peritoneal neutrophil lipoxygenase. Biochem Pharmacol (1985) 0.91
A novel mechanism of murine hepatocyte death inducible by concanavalin A. J Hepatol (1996) 0.90
In vivo and in vitro evidence for extracellular caspase activity released from apoptotic cells. Biochem Biophys Res Commun (2001) 0.90
Interleukin-1 and nitric oxide protect against tumor necrosis factor alpha-induced liver injury through distinct pathways. Hepatology (1995) 0.89
Leukotriene D4 mediates galactosamine/endotoxin-induced hepatitis in mice. Biochem Pharmacol (1987) 0.89
Testing of immunomodulatory properties in vitro. Dev Biol Stand (1996) 0.89
In vivo evidence for protease-catalysed mechanism providing bioactive tumor necrosis factor alpha. Biochem Pharmacol (1990) 0.89