Published in Science on November 05, 1999
Social Circumstances, Parenting Techniques, and Infant Development | NCT02121496
Effect of in utero and early-life conditions on adult health and disease. N Engl J Med (2008) 14.46
Economic, neurobiological, and behavioral perspectives on building America's future workforce. Proc Natl Acad Sci U S A (2006) 5.31
Central effects of stress hormones in health and disease: Understanding the protective and damaging effects of stress and stress mediators. Eur J Pharmacol (2008) 4.82
Oxytocin: the great facilitator of life. Prog Neurobiol (2009) 3.71
Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome. Dialogues Clin Neurosci (2005) 3.70
Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice. J Physiol (2004) 3.52
Adult attachment predicts maternal brain and oxytocin response to infant cues. Neuropsychopharmacology (2009) 3.38
Socioeconomic status and the brain: mechanistic insights from human and animal research. Nat Rev Neurosci (2010) 3.30
Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood. Proc Natl Acad Sci U S A (2006) 3.07
Oxytocin and the neural mechanisms regulating social cognition and affiliative behavior. Front Neuroendocrinol (2009) 2.91
Normal development of brain circuits. Neuropsychopharmacology (2010) 2.64
Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPAR alpha promoter of the offspring. Br J Nutr (2008) 2.55
Protective and damaging effects of stress mediators: central role of the brain. Dialogues Clin Neurosci (2006) 2.50
Naturally occurring variations in maternal behavior in the rat are associated with differences in estrogen-inducible central oxytocin receptors. Proc Natl Acad Sci U S A (2001) 2.43
Brain basis of early parent-infant interactions: psychology, physiology, and in vivo functional neuroimaging studies. J Child Psychol Psychiatry (2007) 2.34
Epigenetic mechanisms and the transgenerational effects of maternal care. Front Neuroendocrinol (2008) 2.33
The plasticity of human maternal brain: longitudinal changes in brain anatomy during the early postpartum period. Behav Neurosci (2010) 2.23
The transcription factor nerve growth factor-inducible protein a mediates epigenetic programming: altering epigenetic marks by immediate-early genes. J Neurosci (2007) 2.21
Towards developing standard operating procedures for pre-clinical testing in the mdx mouse model of Duchenne muscular dystrophy. Neurobiol Dis (2008) 2.20
Paternal transmission of stress-induced pathologies. Biol Psychiatry (2011) 2.07
What's in a smile? Maternal brain responses to infant facial cues. Pediatrics (2008) 2.02
Stress and anxiety: structural plasticity and epigenetic regulation as a consequence of stress. Neuropharmacology (2011) 1.98
Stress Effects on Neuronal Structure: Hippocampus, Amygdala, and Prefrontal Cortex. Neuropsychopharmacology (2015) 1.97
Early skin-to-skin contact for mothers and their healthy newborn infants. Cochrane Database Syst Rev (2012) 1.93
Maternal warmth buffers the effects of low early-life socioeconomic status on pro-inflammatory signaling in adulthood. Mol Psychiatry (2010) 1.90
Prenatal stress, glucocorticoids and the programming of adult disease. Front Behav Neurosci (2009) 1.88
Broad epigenetic signature of maternal care in the brain of adult rats. PLoS One (2011) 1.86
Transgenerational impact of intimate partner violence on methylation in the promoter of the glucocorticoid receptor. Transl Psychiatry (2011) 1.85
Differential immune system DNA methylation and cytokine regulation in post-traumatic stress disorder. Am J Med Genet B Neuropsychiatr Genet (2011) 1.83
Reversing neurodevelopmental disorders in adults. Neuron (2008) 1.80
Social deficits in BTBR T+tf/J mice are unchanged by cross-fostering with C57BL/6J mothers. Int J Dev Neurosci (2007) 1.74
Conceptual challenges and directions for social neuroscience. Neuron (2010) 1.74
The influence of mortality and socioeconomic status on risk and delayed rewards: a life history theory approach. J Pers Soc Psychol (2011) 1.70
Individual development and evolution: experiential canalization of self-regulation. Dev Psychol (2012) 1.66
Exposure to a low dose of bisphenol A during fetal life or in adulthood alters maternal behavior in mice. Environ Health Perspect (2002) 1.64
Increased methylation of glucocorticoid receptor gene (NR3C1) in adults with a history of childhood maltreatment: a link with the severity and type of trauma. Transl Psychiatry (2011) 1.60
Understanding the potency of stressful early life experiences on brain and body function. Metabolism (2008) 1.55
Early parental care is important for hippocampal maturation: evidence from brain morphology in humans. Neuroimage (2009) 1.51
Putative biological mechanisms for the association between early life adversity and the subsequent development of PTSD. Psychopharmacology (Berl) (2010) 1.49
Maximizing resilience through diverse levels of inquiry: Prevailing paradigms, possibilities, and priorities for the future. Dev Psychopathol (2007) 1.48
Onset and exacerbation of obsessive-compulsive disorder in pregnancy and the postpartum period. J Clin Psychiatry (2010) 1.47
Mechanisms of stress in the brain. Nat Neurosci (2015) 1.47
Conserved epigenetic sensitivity to early life experience in the rat and human hippocampus. Proc Natl Acad Sci U S A (2012) 1.45
Epigenetic mechanisms for the early environmental regulation of hippocampal glucocorticoid receptor gene expression in rodents and humans. Neuropsychopharmacology (2012) 1.45
Familial transmission of suicidal behavior. Psychiatr Clin North Am (2008) 1.45
Maternal prenatal cortisol and infant cognitive development: moderation by infant-mother attachment. Biol Psychiatry (2010) 1.43
"Shift-and-Persist" Strategies: Why Low Socioeconomic Status Isn't Always Bad for Health. Perspect Psychol Sci (2012) 1.42
The science of early life toxic stress for pediatric practice and advocacy. Pediatrics (2013) 1.41
Maternal separation alters drug intake patterns in adulthood in rats. Biochem Pharmacol (2006) 1.41
Maternal programming of sexual behavior and hypothalamic-pituitary-gonadal function in the female rat. PLoS One (2008) 1.39
Early experience affects the intergenerational transmission of infant abuse in rhesus monkeys. Proc Natl Acad Sci U S A (2005) 1.34
PTSD and gene variants: new pathways and new thinking. Neuropharmacology (2011) 1.34
Differential patterns of whole-genome DNA methylation in institutionalized children and children raised by their biological parents. Dev Psychopathol (2011) 1.33
The impact of early life family structure on adult social attachment, alloparental behavior, and the neuropeptide systems regulating affiliative behaviors in the monogamous prairie vole (microtus ochrogaster). Front Behav Neurosci (2009) 1.30
Expanding the concept of unresolved mental states: hostile/helpless states of mind on the Adult Attachment Interview are associated with disrupted mother-infant communication and infant disorganization. Dev Psychopathol (2005) 1.29
Inheritance is where physiology meets evolution. J Physiol (2014) 1.29
Effects of mothers' prenatal psychiatric status and postnatal caregiving on infant biobehavioral regulation: can prenatal programming be modified? Early Hum Dev (2007) 1.29
Hypocortisolism as a potential marker of allostatic load in children: associations with family risk and internalizing disorders. Dev Psychopathol (2011) 1.28
Individual differences in novelty-seeking and emotional reactivity correlate with variation in maternal behavior. Horm Behav (2007) 1.24
Quality of early care and childhood trauma: a prospective study of developmental pathways to dissociation. J Nerv Ment Dis (2009) 1.23
Suppression of adult neurogenesis leads to an increased hypothalamo-pituitary-adrenal axis response. Neuroreport (2009) 1.23
Early life stress as a risk factor for mental health: role of neurotrophins from rodents to non-human primates. Neurosci Biobehav Rev (2008) 1.23
Diet and the epigenetic (re)programming of phenotypic differences in behavior. Brain Res (2008) 1.22
Can environmental conditions experienced in early life influence future generations? Proc Biol Sci (2014) 1.22
The three-hit concept of vulnerability and resilience: toward understanding adaptation to early-life adversity outcome. Psychoneuroendocrinology (2013) 1.22
Review. Neurogenetic studies of alcohol addiction. Philos Trans R Soc Lond B Biol Sci (2008) 1.21
Oxytocin and social motivation. Dev Cogn Neurosci (2011) 1.17
Maternal separation as a model of brain-gut axis dysfunction. Psychopharmacology (Berl) (2010) 1.17
Neonatal oxytocin manipulations have long-lasting, sexually dimorphic effects on vasopressin receptors. Neuroscience (2006) 1.16
The pathways from mother's love to baby's future. Front Behav Neurosci (2009) 1.16
Perceived quality of maternal care in childhood and structure and function of mothers' brain. Dev Sci (2010) 1.14
Stress and glucocorticoids promote oligodendrogenesis in the adult hippocampus. Mol Psychiatry (2014) 1.14
Programming social, cognitive, and neuroendocrine development by early exposure to novelty. Proc Natl Acad Sci U S A (2006) 1.13
Prenatal androgen exposure programs metabolic dysfunction in female mice. J Endocrinol (2010) 1.13
From infant attachment disorganization to adult dissociation: relational adaptations or traumatic experiences? Psychiatr Clin North Am (2006) 1.13
Appropriate use of "knockout" mice as models of depression or models of testing the efficacy of antidepressants. Psychopharmacology (Berl) (2001) 1.12
The relevance of epigenetics to PTSD: implications for the DSM-V. J Trauma Stress (2009) 1.12
Effects of the Social Environment and Stress on Glucocorticoid Receptor Gene Methylation: A Systematic Review. Biol Psychiatry (2014) 1.11
DNA methylation: a mechanism for embedding early life experiences in the genome. Child Dev (2012) 1.11
The importance of touch in development. Paediatr Child Health (2010) 1.10
Maternal neglect: oxytocin, dopamine and the neurobiology of attachment. J Neuroendocrinol (2011) 1.10
Cocaine treatment and prenatal environment interact to disrupt intergenerational maternal behavior in rats. Behav Neurosci (2005) 1.08
Intergenerational transmission of self-regulation: A multidisciplinary review and integrative conceptual framework. Psychol Bull (2015) 1.06
Phenotypic checkpoints regulate neuronal development. Trends Neurosci (2010) 1.05
Neurosteroids and GABA(A) Receptor Interactions: A Focus on Stress. Front Neurosci (2011) 1.04
Change in maternal environment induced by cross-fostering alters genetic and epigenetic effects on complex traits in mice. Proc Biol Sci (2009) 1.04
The early life social environment and DNA methylation: DNA methylation mediating the long-term impact of social environments early in life. Epigenetics (2011) 1.03
Maternal programming of defensive responses through sustained effects on gene expression. J Psychiatry Neurosci (2007) 1.02
Development of individual differences in stress responsiveness: an overview of factors mediating the outcome of early life experiences. Psychopharmacology (Berl) (2010) 1.02
Parent-of-origin effects on voluntary exercise levels and body composition in mice. Physiol Genomics (2009) 1.02
Build-ups in the supply chain of the brain: on the neuroenergetic cause of obesity and type 2 diabetes mellitus. Front Neuroenergetics (2009) 1.01
Epigenetic effects of stress and corticosteroids in the brain. Front Cell Neurosci (2012) 1.01
Epigenetics of early child development. Front Psychiatry (2011) 1.01
Maternal prenatal depressive symptoms predict infant NR3C1 1F and BDNF IV DNA methylation. Epigenetics (2015) 1.00
Epigenetics in mood disorders. Environ Health Prev Med (2007) 1.00
Early-life experience, epigenetics, and the developing brain. Neuropsychopharmacology (2014) 1.00
Baby stimuli and the parent brain: functional neuroimaging of the neural substrates of parent-infant attachment. Psychiatry (Edgmont) (2008) 0.99
Adolescents with and without gestational cocaine exposure: Longitudinal analysis of inhibitory control, memory and receptive language. Neurotoxicol Teratol (2011) 0.99
The meaning of weaning: influence of the weaning period on behavioral development in mice. Dev Neurosci (2009) 0.98
Contributions of Neuroscience to Our Understanding of Cognitive Development. Curr Dir Psychol Sci (2008) 0.98
Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress. Science (1997) 8.90
Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. Gene Ther (1999) 8.28
DNA damage-induced activation of p53 by the checkpoint kinase Chk2. Science (2000) 7.85
The plasticity of dendritic cell responses to pathogens and their components. Science (2001) 5.58
Cortisol levels during human aging predict hippocampal atrophy and memory deficits. Nat Neurosci (1998) 4.76
Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms. Science (1999) 4.61
Cryptochromes: blue light receptors for plants and animals. Science (1999) 4.29
Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats. Brain Res Mol Brain Res (1993) 4.13
B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production. Nat Immunol (2001) 4.10
Validity and reproducibility of the food frequency questionnaire used in the Shanghai Women's Health Study. Eur J Clin Nutr (2004) 3.92
Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB. J Biol Chem (1999) 3.81
Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells. Proc Natl Acad Sci U S A (2000) 3.69
Structure of the O antigen of Escherichia coli K-12 and the sequence of its rfb gene cluster. J Bacteriol (1994) 3.61
Maternal care during infancy regulates the development of neural systems mediating the expression of fearfulness in the rat. Proc Natl Acad Sci U S A (1998) 3.58
The role of the medial prefrontal cortex (cingulate gyrus) in the regulation of hypothalamic-pituitary-adrenal responses to stress. J Neurosci (1993) 3.47
Maternal care, hippocampal synaptogenesis and cognitive development in rats. Nat Neurosci (2000) 3.42
Bronchodilator responsiveness in patients with COPD. Eur Respir J (2008) 3.13
Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity. Nat Med (2001) 2.87
Prolonged air leak following radical upper lobectomy: an analysis of incidence and possible risk factors. Chest (1998) 2.82
Maturation of the adrenocortical stress response: neuroendocrine control mechanisms and the stress hyporesponsive period. Brain Res (1986) 2.73
Solution structure of the homodimeric core domain of Escherichia coli histidine kinase EnvZ. Nat Struct Biol (1999) 2.72
NMR structure of the histidine kinase domain of the E. coli osmosensor EnvZ. Nature (1998) 2.69
p21(CIP1) and p57(KIP2) control muscle differentiation at the myogenin step. Genes Dev (1999) 2.58
Neuronal units linked to microvascular modules in cerebral cortex: response elements for imaging the brain. Cereb Cortex (1997) 2.54
The C termini of Arabidopsis cryptochromes mediate a constitutive light response. Cell (2000) 2.53
Past adult lead exposure is linked to neurodegeneration measured by brain MRI. Neurology (2006) 2.52
Can poverty get under your skin? basal cortisol levels and cognitive function in children from low and high socioeconomic status. Dev Psychopathol (2001) 2.48
Long-term behavioral and neuroendocrine adaptations to adverse early experience. Prog Brain Res (2000) 2.45
Hand-held thoracic sonography for detecting post-traumatic pneumothoraces: the Extended Focused Assessment with Sonography for Trauma (EFAST). J Trauma (2004) 2.44
Naturally occurring variations in maternal behavior in the rat are associated with differences in estrogen-inducible central oxytocin receptors. Proc Natl Acad Sci U S A (2001) 2.43
Hypermethylation of the death-associated protein (DAP) kinase promoter and aggressiveness in stage I non-small-cell lung cancer. J Natl Cancer Inst (2000) 2.39
Early environmental regulation of forebrain glucocorticoid receptor gene expression: implications for adrenocortical responses to stress. Dev Neurosci (1996) 2.34
Regulation of the Bub2/Bfa1 GAP complex by Cdc5 and cell cycle checkpoints. Cell (2001) 2.33
Rapid mini-preparation of fungal DNA for PCR. J Clin Microbiol (2000) 2.32
Child's stress hormone levels correlate with mother's socioeconomic status and depressive state. Biol Psychiatry (2000) 2.28
Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL/6 mice. J Immunol (2001) 2.27
The Arabidopsis CHL1 protein plays a major role in high-affinity nitrate uptake. Proc Natl Acad Sci U S A (1998) 2.23
Urokinase receptor and fibronectin regulate the ERK(MAPK) to p38(MAPK) activity ratios that determine carcinoma cell proliferation or dormancy in vivo. Mol Biol Cell (2001) 2.21
Do early-life events permanently alter behavioral and hormonal responses to stressors? Int J Dev Neurosci (1998) 2.19
Effects of N-(4-hydroxyphenyl)retinamide on hTERT expression in the bronchial epithelium of cigarette smokers. J Natl Cancer Inst (2001) 2.18
Activation of protein kinase C triggers its ubiquitination and degradation. Mol Cell Biol (1998) 2.15
Long-term impact of smoking on lung epithelial proliferation in current and former smokers. J Natl Cancer Inst (2001) 2.13
Variations in maternal behaviour are associated with differences in oxytocin receptor levels in the rat. J Neuroendocrinol (2000) 2.00
Concomitant sensitivity to orientation, direction, and color of cells in layers 2, 3, and 4 of monkey striate cortex. J Neurosci (1995) 1.97
Hydroporation as the mechanism of hydrodynamic delivery. Gene Ther (2004) 1.97
Basal cortisol levels and cognitive deficits in human aging. J Neurosci (1994) 1.97
Variations in maternal care in infancy regulate the development of stress reactivity. Biol Psychiatry (2000) 1.91
Raf-1 kinase and exoenzyme S interact with 14-3-3zeta through a common site involving lysine 49. J Biol Chem (1997) 1.83
Like mother, like daughter: evidence for non-genomic transmission of parental behavior and stress responsivity. Prog Brain Res (2001) 1.83
Naturally occurring differences in maternal care are associated with the expression of oxytocin and vasopressin (V1a) receptors: gender differences. J Neuroendocrinol (2002) 1.81
Overexpression of cyclin B1 in early-stage non-small cell lung cancer and its clinical implication. Cancer Res (2000) 1.81
Prion protein expression in different species: analysis with a panel of new mAbs. Proc Natl Acad Sci U S A (1998) 1.80
The RIP-like kinase, RIP3, induces apoptosis and NF-kappaB nuclear translocation and localizes to mitochondria. FEBS Lett (2000) 1.80
C-terminal half of Salmonella enterica WbaP (RfbP) is the galactosyl-1-phosphate transferase domain catalyzing the first step of O-antigen synthesis. J Bacteriol (1996) 1.79
Maternal care and the development of stress responses. Curr Opin Neurobiol (1999) 1.79
Variations in the hypothalamic-pituitary-adrenal response to stress during the estrous cycle in the rat. Endocrinology (1991) 1.77
The effects of early rearing environment on the development of GABAA and central benzodiazepine receptor levels and novelty-induced fearfulness in the rat. Neuropsychopharmacology (2000) 1.76
Identification and functional characterization of DR6, a novel death domain-containing TNF receptor. FEBS Lett (1998) 1.75
Development of adult ethanol preference and anxiety as a consequence of neonatal maternal separation in Long Evans rats and reversal with antidepressant treatment. Psychopharmacology (Berl) (2001) 1.71
The tumour-stromal interaction between intratumoral c-Met and stromal hepatocyte growth factor associated with tumour growth and prognosis in non-small-cell lung cancer patients. Br J Cancer (2004) 1.71
5'-heterogeneity of glucocorticoid receptor messenger RNA is tissue specific: differential regulation of variant transcripts by early-life events. Mol Endocrinol (2000) 1.69
Coproantigen detection for immunodiagnosis of echinococcosis and taeniasis in dogs and humans. Parasitology (1992) 1.66
The effects of chronic antidepressant treatment in an animal model of anxiety. Psychopharmacology (Berl) (1988) 1.63
Enduring effects of chronic corticosterone treatment on spatial learning, synaptic plasticity, and hippocampal neuropathology in young and mid-aged rats. J Neurosci (1995) 1.63
Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60
Induction of specific T-cell tolerance by adenovirus-transfected, Fas ligand-producing antigen presenting cells. Nat Biotechnol (1998) 1.59
Siglec-8. A novel eosinophil-specific member of the immunoglobulin superfamily. J Biol Chem (2000) 1.59
Partial reversal of the effect of maternal care on cognitive function through environmental enrichment. Neuroscience (2003) 1.58
Sex-specific effects of prenatal stress on hypothalamic-pituitary-adrenal responses to stress and brain glucocorticoid receptor density in adult rats. Brain Res Dev Brain Res (1995) 1.56
Stress-induced declarative memory impairment in healthy elderly subjects: relationship to cortisol reactivity. J Clin Endocrinol Metab (1997) 1.56
An abundant DNA binding protein from the hyperthermophilic archaeon Sulfolobus shibatae affects DNA supercoiling in a temperature-dependent fashion. J Bacteriol (2000) 1.51
Amniotic membrane collagen content and type distribution in women with preterm premature rupture of the membranes in pregnancy. Br J Obstet Gynaecol (1997) 1.51
Hypothalamic-pituitary-adrenal activity in aged, cognitively impaired and cognitively unimpaired rats. J Neurosci (1990) 1.51
Loss of membranous E-cadherin expression in pancreatic cancer: correlation with lymph node metastasis, high grade, and advanced stage. J Pathol (1994) 1.51
Epigenetic programming of phenotypic variations in reproductive strategies in the rat through maternal care. J Neuroendocrinol (2008) 1.50
Increased cortisol levels and impaired cognition in human aging: implication for depression and dementia in later life. Rev Neurosci (1999) 1.47
Redox control of K+ channel remodeling in rat ventricle. J Mol Cell Cardiol (2005) 1.47
Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models. Cancer Res (2001) 1.46
Identification and characterization of a novel siglec, siglec-7, expressed by human natural killer cells and monocytes. J Biol Chem (1999) 1.44
Maternal care, gene expression, and the development of individual differences in stress reactivity. Ann N Y Acad Sci (1999) 1.44
Defects in insulin secretion and action in women with a history of gestational diabetes. Diabetes (1995) 1.43
Amino-acid sequence of porcine pepsin. Proc Natl Acad Sci U S A (1973) 1.43
Observation of a centrality-dependent dijet asymmetry in lead-lead collisions at sqrt[S(NN)] =2.76 TeV with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.41
Retinol-binding protein 4 is associated with components of the metabolic syndrome, but not with insulin resistance, in men with type 2 diabetes or coronary artery disease. Diabetologia (2007) 1.41
A survey of men who have sex with men: mainland China. Am J Public Health (2000) 1.41
Identification of a novel activation-inducible protein of the tumor necrosis factor receptor superfamily and its ligand. J Biol Chem (1999) 1.41
Structural impact of hydrodynamic injection on mouse liver. Gene Ther (2006) 1.41
Pds1 phosphorylation in response to DNA damage is essential for its DNA damage checkpoint function. Genes Dev (2001) 1.40
Measurement of dijet azimuthal decorrelations in pp collisions at sqrt(s)=7 TeV. Phys Rev Lett (2011) 1.39
High-fat feeding alters both basal and stress-induced hypothalamic-pituitary-adrenal activity in the rat. Am J Physiol (1997) 1.39
The role of corticotropin-releasing factor--norepinephrine systems in mediating the effects of early experience on the development of behavioral and endocrine responses to stress. Biol Psychiatry (1999) 1.39
Neonatal endotoxin exposure alters the development of the hypothalamic-pituitary-adrenal axis: early illness and later responsivity to stress. J Neurosci (1995) 1.38
The intratumoral expression of vascular endothelial growth factor and interleukin-8 associated with angiogenesis in nonsmall cell lung carcinoma patients. Cancer (2001) 1.38
Structural and functional characterization of human CXCR4 as a chemokine receptor and HIV-1 co-receptor by mutagenesis and molecular modeling studies. J Biol Chem (2001) 1.38