Published in Development on December 01, 1999
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Osteocyte control of bone formation via sclerostin, a novel BMP antagonist. EMBO J (2003) 4.32
Regulation of limb patterning by extracellular microfibrils. J Cell Biol (2001) 2.37
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Regulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin. J Cell Biol (2006) 1.42
Interdigital webbing retention in bat wings illustrates genetic changes underlying amniote limb diversification. Proc Natl Acad Sci U S A (2006) 1.37
A misplaced lncRNA causes brachydactyly in humans. J Clin Invest (2012) 1.36
Noggin is required for normal lobe patterning and ductal budding in the mouse prostate. Dev Biol (2007) 1.26
The bone morphogenetic protein antagonist gremlin 1 is overexpressed in human cancers and interacts with YWHAH protein. BMC Cancer (2006) 1.25
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Gremlin gene expression in bovine retinal pericytes exposed to elevated glucose. Br J Ophthalmol (2005) 1.15
The nucleocytoplasmic shuttling protein CIZ reduces adult bone mass by inhibiting bone morphogenetic protein-induced bone formation. J Exp Med (2005) 1.08
Identification of genes associated with regenerative success of Xenopus laevis hindlimbs. BMC Dev Biol (2008) 1.03
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Gremlin is overexpressed in lung adenocarcinoma and increases cell growth and proliferation in normal lung cells. PLoS One (2012) 0.89
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Noggin is required for early development of murine upper incisors. J Dent Res (2012) 0.83
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Negative Smad expression and regulation in the developing chick limb. PLoS One (2009) 0.77
Wattles in goats are associated with the FMN1/GREM1 region on chromosome 10. Anim Genet (2015) 0.77
Saunders's framework for understanding limb development as a platform for investigating limb evolution. Dev Biol (2016) 0.76
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Genome-wide association meta-analyses identified 1q43 and 2q32.2 for hip Ward's triangle areal bone mineral density. Bone (2016) 0.75
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Gelatin device for the delivery of growth factors involved in endochondral ossification. PLoS One (2017) 0.75
Gene expression profiles in Rana pirica tadpoles following exposure to a predation threat. BMC Genomics (2015) 0.75
A functional variant in GREM1 confers risk for colorectal cancer by disrupting a hsa-miR-185-3p binding site. Oncotarget (2017) 0.75
Neural induction by the secreted polypeptide noggin. Science (1993) 3.45
The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities. Mol Cell (1998) 2.89
The novel Cer-like protein Caronte mediates the establishment of embryonic left-right asymmetry. Nature (1999) 2.08
Essential requirement of BMPs-2/4 for both osteoblast and osteoclast formation in murine bone marrow cultures from adult mice: antagonism by noggin. J Bone Miner Res (2000) 2.03
Identification of mammalian noggin and its expression in the adult nervous system. J Neurosci (1995) 1.81
Role of TGF beta s and BMPs as signals controlling the position of the digits and the areas of interdigital cell death in the developing chick limb autopod. Development (1996) 1.73
Analysis of the molecular cascade responsible for mesodermal limb chondrogenesis: Sox genes and BMP signaling. Dev Biol (2003) 1.72
Skeletal overexpression of noggin results in osteopenia and reduced bone formation. Endocrinology (2003) 1.60
Role of BMP-2 and OP-1 (BMP-7) in programmed cell death and skeletogenesis during chick limb development. Development (1997) 1.56
Morphogenesis of digits in the avian limb is controlled by FGFs, TGFbetas, and noggin through BMP signaling. Dev Biol (1998) 1.32
Expression and function of Gdf-5 during digit skeletogenesis in the embryonic chick leg bud. Dev Biol (1999) 1.28
Morphological changes in the normal pattern of ventricular myoarchitecture in the developing human heart. Anat Rec (1995) 1.14
Human disease-causing NOG missense mutations: effects on noggin secretion, dimer formation, and bone morphogenetic protein binding. Proc Natl Acad Sci U S A (2001) 1.14
Myocardial fiber architecture of the human heart ventricles. Anat Rec (1982) 1.13
Expression of BMP-7 and USAG-1 (a BMP antagonist) in kidney development and injury. Kidney Int (2007) 1.10
The bone morphogenetic proteins antagonist Noggin inhibits membranous ossification. J Bone Miner Res (2001) 1.06
Bone morphogenetic proteins induce gremlin, a protein that limits their activity in osteoblasts. Endocrinology (2000) 1.05
Biochemical and biophysical characterization of refolded Drosophila DPP, a homolog of bone morphogenetic proteins 2 and 4. J Biol Chem (1998) 1.05
Bone morphogenetic proteins regulate interdigital cell death in the avian embryo. Ann N Y Acad Sci (1999) 1.03
Morphological diversity of the avian foot is related with the pattern of msx gene expression in the developing autopod. Dev Biol (1998) 1.02
Retinoic acid regulates programmed cell death through BMP signalling. Nat Cell Biol (1999) 1.01
Experimental analysis of the role of ECM in the patterning of the distal tendons of the developing limb bud. Cell Differ Dev (1990) 1.00
Internucleosomal DNA fragmentation and programmed cell death (apoptosis) in the interdigital tissue of the embryonic chick leg bud. J Cell Sci (1993) 0.98
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In vivo inhibition of programmed cell death by local administration of FGF-2 and FGF-4 in the interdigital areas of the embryonic chick leg bud. Anat Embryol (Berl) (1996) 0.96
Expression of Sox8, Sox9 and Sox10 in the developing valves and autonomic nerves of the embryonic heart. Mech Dev (2002) 0.96
Control of digit formation by activin signalling. Development (1999) 0.95
Scanning and light microscope studies of the development of the chick embryo semilunar heart valves. Anat Embryol (Berl) (1979) 0.95
Immunohistological and ultrastructural study of the developing tendons of the avian foot. Anat Embryol (Berl) (1995) 0.95
Sustained induction of neuronal addition to the adult rat neostriatum by AAV4-delivered noggin and BDNF. Gene Ther (2011) 0.95
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Ventricular myocardial architecture in marine fishes. Anat Rec (1987) 0.93
Cell death during the formation of tubular heart of the chick embryo. J Embryol Exp Morphol (1975) 0.92
Noggin arrests stromal cell differentiation in vitro. Bone (2003) 0.92
Role of FGFs in the control of programmed cell death during limb development. Development (2001) 0.92
The cerebellar arteries: cortical patterns and vascularization of the cerebellar nuclei. Acta Anat (Basel) (1982) 0.92
Interdigital tissue chondrogenesis induced by surgical removal of the ectoderm in the embryonic chick leg bud. J Embryol Exp Morphol (1986) 0.91
Compositional and structural heterogenicity of the cardiac jelly of the chick embryo tubular heart: a TEM, SEM and histochemical study. J Embryol Exp Morphol (1980) 0.90
Development of mouse semilunar valves. Anat Embryol (Berl) (1980) 0.87
Cytological and cytochemical studies of the necrotic area of the bulbus of the chick embryo heart: phagocytosis by developing myocardial cells. J Embryol Exp Morphol (1977) 0.87
The surface coat of embryonic limb mesenchymal cells during morphogenetic cell death. Exp Cell Res (1981) 0.86
Endocardial cell polarity during the looping of the heart in the chick embryo. Dev Biol (1982) 0.84
Coordinated and sequential activation of neutral and acidic DNases during interdigital cell death in the embryonic limb. Apoptosis (2010) 0.84
Mouse embryos lacking RXR alpha are resistant to retinoic-acid-induced limb defects. Development (1995) 0.84
Comparative analysis of the expression and regulation of Wnt5a, Fz4, and Frzb1 during digit formation and in micromass cultures. Dev Dyn (2002) 0.84
Maturation of the extracellular material of the semilunar heart values in the mouse. A histochemical analysis of collagen and mucopolysaccharides. Anat Embryol (Berl) (1981) 0.82
Noggin gene delivery inhibits cementoblast-induced mineralization. Connect Tissue Res (2004) 0.82
Malformations of the semilunar valves produced in chick embryos by mechanical interference with cardiogenesis. An experimental approach to the role of hemodynamics in valvular development. Anat Embryol (Berl) (1983) 0.82
Experimental analysis of the in vivo chondrogenic potential of the interdigital mesenchyme of the chick leg bud subjected to local ectodermal removal. Dev Biol (1989) 0.81
Histochemical and ultrastructural changes in the extracellular matrix of the developing chick semilunar heart valves. Acta Anat (Basel) (1991) 0.81
Pattern regulation in the chick autopodium at advanced stages of embryonic development. Dev Dyn (1994) 0.81
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Formation of extra-digits induced by surgical removal of the apical ectodermal ridge of the chick embryo leg bud in the stages previous to the onset of interdigital cell death. Anat Embryol (Berl) (1987) 0.80
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Changes in the endothelial morphology of the developing semilunar heart valves. A TEM and SEM study in the chick. Anat Embryol (Berl) (1983) 0.79
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Cathepsin D gene expression outlines the areas of physiological cell death during embryonic development. Dev Dyn (2007) 0.78
Fine structure of the regressing interdigital membranes during the formation of the digits of the chick embryo leg bud. J Embryol Exp Morphol (1983) 0.78
Structural arrangement of the extracellular matrix network during myocardial development in the chick embryo heart. Anat Embryol (Berl) (1991) 0.78
Understanding near/far-field engineering of optical dimer antennas through geometry modification. Opt Express (2009) 0.78
Cell death in the embryonic developing limb. Scanning Microsc (1995) 0.77