Interactions of the sponge-derived antimitotic tripeptide hemiasterlin with tubulin: comparison with dolastatin 10 and cryptophycin 1.

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🔗 View Article (PMID 10572005)

Published in Biochemistry on October 26, 1999

Authors

R Bai1, N A Durso, D L Sackett, E Hamel

Author Affiliations

1: Science Applications International Corporation-Frederick, National Cancer Institute, Frederick Cancer Research and Development Center, Maryland 21702, USA.

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Users' guides to the medical literature. III. How to use an article about a diagnostic test. A. Are the results of the study valid? Evidence-Based Medicine Working Group. JAMA (1994) 7.85

Controversy in the detection of disease. Lancet (1975) 7.85

How to keep up with the medical literature: V. Access by personal computer to the medical literature. Ann Intern Med (1986) 7.36

Controversy in counting and attributing events in clinical trials. N Engl J Med (1979) 7.25

Randomised clinical trial of strategies for improving medication compliance in primary hypertension. Lancet (1975) 7.22

Users' guides to the medical literature. I. How to get started. The Evidence-Based Medicine Working Group. JAMA (1993) 6.83

A utility maximization model for evaluation of health care programs. Health Serv Res (1972) 6.67

Users' guides to the medical literature. II. How to use an article about therapy or prevention. B. What were the results and will they help me in caring for my patients? Evidence-Based Medicine Working Group. JAMA (1994) 6.27

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Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization. J Biol Chem (1997) 5.51

Users' guides to the medical literature. IX. A method for grading health care recommendations. Evidence-Based Medicine Working Group. JAMA (1995) 5.28

Problems in the handling of clinical and research evidence by medical practitioners. Arch Intern Med (1983) 5.16

A randomized trial of continuing medical education. N Engl J Med (1982) 4.95

Improvement of medication compliance in uncontrolled hypertension. Lancet (1976) 4.84

The Burlington randomized trial of the nurse practitioner: health outcomes of patients. Ann Intern Med (1974) 4.37

The utility of different health states as perceived by the general public. J Chronic Dis (1978) 3.65

An empirical demonstration of Berkson's bias. J Chronic Dis (1978) 3.48

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Diagnosis and treatment of chronic arterial insufficiency of the lower extremities: a critical review. Circulation (1996) 3.23

Rules of evidence and clinical recommendations on the use of antithrombotic agents. Chest (1986) 3.16

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The science of the art of the clinical examination. JAMA (1992) 1.48

Antitumor agents. Part 204: synthesis and biological evaluation of substituted 2-aryl quinazolinones. Bioorg Med Chem Lett (2001) 1.48

Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites. J Biol Chem (1990) 1.47

Self-recording of blood pressure in the management of hypertension. Can Med Assoc J (1978) 1.46

The usefulness of laboratory tests in health-screening programs. Clin Chem (1973) 1.45

Applying the results of trials and systematic reviews to individual patients. ACP J Club (1998) 1.45

Concordance for coronary risk factors among spouses. Circulation (1975) 1.44

Astroglial and vascular interactions of noradrenaline terminals in the rat cerebral cortex. J Cereb Blood Flow Metab (1997) 1.44

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Non-use and misuse of measles vaccine. Can Fam Physician (1973) 1.40