Published in J Biol Chem on December 10, 1999
Amphetamine-induced loss of human dopamine transporter activity: an internalization-dependent and cocaine-sensitive mechanism. Proc Natl Acad Sci U S A (2000) 2.27
The dopamine transporter constitutively internalizes and recycles in a protein kinase C-regulated manner in stably transfected PC12 cell lines. J Biol Chem (2003) 2.14
N-terminal phosphorylation of the dopamine transporter is required for amphetamine-induced efflux. PLoS Biol (2004) 1.94
Nonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization. Nat Neurosci (2005) 1.68
Generation of an activating Zn(2+) switch in the dopamine transporter: mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle. Proc Natl Acad Sci U S A (2002) 1.68
The N terminus of monoamine transporters is a lever required for the action of amphetamines. J Biol Chem (2010) 1.58
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Three ubiquitin conjugation sites in the amino terminus of the dopamine transporter mediate protein kinase C-dependent endocytosis of the transporter. Mol Biol Cell (2006) 1.50
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Protein kinase Cbeta is a critical regulator of dopamine transporter trafficking and regulates the behavioral response to amphetamine in mice. J Pharmacol Exp Ther (2008) 1.31
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Visualization of dopamine transporter trafficking in live neurons by use of fluorescent cocaine analogs. J Neurosci (2009) 1.26
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Dieldrin exposure induces oxidative damage in the mouse nigrostriatal dopamine system. Exp Neurol (2007) 1.24
Analyses of the recycling receptor, FcRn, in live cells reveal novel pathways for lysosomal delivery. Traffic (2009) 1.24
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Negative regulation of dopamine transporter endocytosis by membrane-proximal N-terminal residues. J Neurosci (2009) 1.16
Lysine 63-linked polyubiquitination of the dopamine transporter requires WW3 and WW4 domains of Nedd4-2 and UBE2D ubiquitin-conjugating enzymes. J Biol Chem (2010) 1.13
Trafficking of dopamine transporters in psychostimulant actions. Semin Cell Dev Biol (2009) 1.11
Differential subcellular distribution of endosomal compartments and the dopamine transporter in dopaminergic neurons. Mol Cell Neurosci (2010) 1.04
Role of the dopamine transporter in the action of psychostimulants, nicotine, and other drugs of abuse. CNS Neurol Disord Drug Targets (2008) 1.03
Protein kinase C-dependent ubiquitination and clathrin-mediated endocytosis of the cationic amino acid transporter CAT-1. J Biol Chem (2011) 1.03
Substrates dissociate dopamine transporter oligomers. J Neurochem (2007) 1.02
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HIV-1 Tat protein decreases dopamine transporter cell surface expression and vesicular monoamine transporter-2 function in rat striatal synaptosomes. J Neuroimmune Pharmacol (2012) 0.96
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Effects of N-linked glycosylation on the creatine transporter. Biochem J (2006) 0.92
Protein interacting with C kinase 1 (PICK1) reduces reinsertion rates of interaction partners sorted to Rab11-dependent slow recycling pathway. J Biol Chem (2012) 0.91
Effect of environmental enrichment on methylphenidate-induced locomotion and dopamine transporter dynamics. Behav Brain Res (2011) 0.91
Dopamine transporter endocytic trafficking in striatal dopaminergic neurons: differential dependence on dynamin and the actin cytoskeleton. J Neurosci (2013) 0.89
The PKC inhibitor Ro31-8220 blocks acute amphetamine-induced dopamine overflow in the nucleus accumbens. Neurosci Lett (2009) 0.89
Dopamine transporter trafficking: rapid response on demand. Future Neurol (2010) 0.88
Regulation of the Dopamine and Vesicular Monoamine Transporters: Pharmacological Targets and Implications for Disease. Pharmacol Rev (2015) 0.88
Flotillins regulate membrane mobility of the dopamine transporter but are not required for its protein kinase C dependent endocytosis. Traffic (2013) 0.87
Rab 11 regulates constitutive dopamine transporter trafficking and function in N2A neuroblastoma cells. Neurosci Lett (2009) 0.87
Monoamine transporters: vulnerable and vital doorkeepers. Prog Mol Biol Transl Sci (2011) 0.87
Palmitoylation controls dopamine transporter kinetics, degradation, and protein kinase C-dependent regulation. J Biol Chem (2010) 0.87
Differential targeting of the dopamine transporter to recycling or degradative pathways during amphetamine- or PKC-regulated endocytosis in dopamine neurons. FASEB J (2013) 0.87
Regulation of dopamine transporter activity by carboxypeptidase E. Mol Brain (2009) 0.85
Membrane-permeable C-terminal dopamine transporter peptides attenuate amphetamine-evoked dopamine release. J Biol Chem (2013) 0.85
Cyclin-dependent kinase 5 inhibitors: inhibition of dopamine transporter activity. Mol Pharmacol (2009) 0.84
Regulation of dynamin 2 and G protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration. Synapse (2009) 0.83
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Melittin stimulates fatty acid release through non-phospholipase-mediated mechanisms and interacts with the dopamine transporter and other membrane-spanning proteins. Eur J Pharmacol (2010) 0.80
Amphetamine activates Rho GTPase signaling to mediate dopamine transporter internalization and acute behavioral effects of amphetamine. Proc Natl Acad Sci U S A (2015) 0.80
Constitutive endocytosis and turnover of the neuronal glycine transporter GlyT2 is dependent on ubiquitination of a C-terminal lysine cluster. PLoS One (2013) 0.80
Reciprocal Phosphorylation and Palmitoylation Control Dopamine Transporter Kinetics. J Biol Chem (2015) 0.79
Striatal dopamine neurotransmission: regulation of release and uptake. Basal Ganglia (2016) 0.79
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The C. elegans model in toxicity testing. J Appl Toxicol (2016) 0.77
Brain slice biotinylation: an ex vivo approach to measure region-specific plasma membrane protein trafficking in adult neurons. J Vis Exp (2014) 0.77
Melittin initiates dopamine transporter internalization and recycling in transfected HEK-293 cells. Eur J Pharmacol (2012) 0.77
Methamphetamine-induced short-term increase and long-term decrease in spatial working memory affects protein Kinase M zeta (PKMζ), dopamine, and glutamate receptors. Front Behav Neurosci (2014) 0.77
Identification of a Vav2-dependent mechanism for GDNF/Ret control of mesolimbic DAT trafficking. Nat Neurosci (2015) 0.77
Classic Studies on the Interaction of Cocaine and the Dopamine Transporter. Clin Psychopharmacol Neurosci (2015) 0.76
Differential Internalization Rates and Postendocytic Sorting of the Norepinephrine and Dopamine Transporters Are Controlled by Structural Elements in the N Termini. J Biol Chem (2016) 0.76
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Insights in how amphetamine ROCKs (Rho-associated containing kinase) membrane protein trafficking. Proc Natl Acad Sci U S A (2015) 0.75
Molecular mechanism: the human dopamine transporter histidine 547 regulates basal and HIV-1 Tat protein-inhibited dopamine transport. Sci Rep (2016) 0.75
Ctr9, a Protein in the Transcription Complex Paf1, Regulates Dopamine Transporter Activity at the Plasma Membrane. J Biol Chem (2015) 0.75
The Dopamine Transporter Recycles Via A Retromer-Dependent Post-Endocytic Mechanism: Tracking Studies Using A Novel Fluorophore-Coupling Approach. J Neurosci (2017) 0.75
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