Spatial learning deficit in dopamine D(1) receptor knockout mice.

PubWeight™: 1.27‹?› | Rank: Top 10%

🔗 View Article (PMID 10585522)

Published in Eur J Pharmacol on October 27, 1999

Authors

M El-Ghundi1, P J Fletcher, J Drago, D R Sibley, B F O'Dowd, S R George

Author Affiliations

1: Department of Pharmacology, University of Toronto, 1 King's College Circle, Toronto, Ontario, Canada.

Articles citing this

Disruption of NMDAR-dependent burst firing by dopamine neurons provides selective assessment of phasic dopamine-dependent behavior. Proc Natl Acad Sci U S A (2009) 3.15

Lack of self-administration of cocaine in dopamine D1 receptor knock-out mice. J Neurosci (2007) 1.73

Modulation of hippocampus-dependent learning and synaptic plasticity by nicotine. Mol Neurobiol (2008) 1.71

Withdrawal from chronic nicotine administration impairs contextual fear conditioning in C57BL/6 mice. J Neurosci (2005) 1.68

Persistent cognitive dysfunction after traumatic brain injury: A dopamine hypothesis. Neurosci Biobehav Rev (2009) 1.57

The effects of DHBE and MLA on nicotine-induced enhancement of contextual fear conditioning in C57BL/6 mice. Psychopharmacology (Berl) (2005) 1.39

Dopaminergic modulation of the persistence of one-trial hippocampus-dependent memory. Learn Mem (2006) 1.35

Anxiogenic-like behavioral phenotype of mice deficient in phosphodiesterase 4B (PDE4B). Neuropsychopharmacology (2007) 1.29

Dopamine D1 receptors regulate protein synthesis-dependent long-term recognition memory via extracellular signal-regulated kinase 1/2 in the prefrontal cortex. Learn Mem (2007) 1.21

Cognition in mouse models of schizophrenia susceptibility genes. Schizophr Bull (2009) 1.11

beta2 subunit-containing nicotinic receptors mediate the enhancing effect of nicotine on trace cued fear conditioning in C57BL/6 mice. Psychopharmacology (Berl) (2006) 1.11

Maternal immune activation alters nonspatial information processing in the hippocampus of the adult offspring. Brain Behav Immun (2010) 1.07

Dopaminergic modulation of the hippocampal neuropil proteome identified by bioorthogonal noncanonical amino acid tagging (BONCAT). Proteomics (2012) 1.05

Simultaneous absence of dopamine D1 and D2 receptor-mediated signaling is lethal in mice. Proc Natl Acad Sci U S A (2004) 1.05

Dopamine D1/D5 receptors mediate informational saliency that promotes persistent hippocampal long-term plasticity. Cereb Cortex (2012) 1.02

Striatal Signaling in L-DOPA-Induced Dyskinesia: Common Mechanisms with Drug Abuse and Long Term Memory Involving D1 Dopamine Receptor Stimulation. Front Neuroanat (2011) 1.01

Modeling cognitive dysfunction in neurofibromatosis-1. Trends Neurosci (2013) 1.00

Action of modafinil--increased motivation via the dopamine transporter inhibition and D1 receptors? Biol Psychiatry (2010) 0.99

Dopamine deficiency underlies learning deficits in neurofibromatosis-1 mice. Ann Neurol (2012) 0.97

Dopamine type-1 receptor binding in major depressive disorder assessed using positron emission tomography and [11C]NNC-112. Neuropsychopharmacology (2008) 0.92

A behavioral genetics approach to understanding D1 receptor involvement in phasic dopamine signaling. Mol Cell Neurosci (2010) 0.88

Functional division of hippocampal area CA1 via modulatory gating of entorhinal cortical inputs. Hippocampus (2011) 0.88

Differential roles of the dopamine 1-class receptors, D1R and D5R, in hippocampal dependent memory. Proc Natl Acad Sci U S A (2014) 0.88

Habituation and sensitization of acoustic startle: opposite influences of dopamine D1 and D2-family receptors. Neurobiol Learn Mem (2008) 0.86

Differential effects of dopamine receptor D1-type and D2-type antagonists and phase of the estrous cycle on social learning of food preferences, feeding, and social interactions in mice. Neuropsychopharmacology (2011) 0.83

Redundant catecholamine signaling consolidates fear memory via phospholipase C. J Neurosci (2012) 0.82

Frequency-dependent signal transmission and modulation by neuromodulators. Front Neurosci (2008) 0.81

Context dependent effects of ventral tegmental area inactivation on spatial working memory. Behav Brain Res (2009) 0.80

Plasticity in D1-like receptor expression is associated with different components of cognitive processes. PLoS One (2012) 0.78

Differentiation of forebrain and hippocampal dopamine 1-class receptors, D1R and D5R, in spatial learning and memory. Hippocampus (2015) 0.77

Involvement of the Striatal Medium Spiny Neurons of the Direct Pathway in the Motor Stimulant Effects of Phencyclidine. Int J Neuropsychopharmacol (2015) 0.75

Current Concepts on the Physiopathological Relevance of Dopaminergic Receptors. Front Cell Neurosci (2017) 0.75

Effects of dopamine D4 receptor antagonist on spontaneous alternation in rats. Behav Brain Funct (2008) 0.75

Social defeat stress induces depression-like behavior and alters spine morphology in the hippocampus of adolescent male C57BL/6 mice. Neurobiol Stress (2016) 0.75

Does Early Environmental Complexity Influence Tyrosine Hydroxylase in the Chicken Hippocampus and "Prefrontal" Caudolateral Nidopallium? Front Vet Sci (2016) 0.75

Articles by these authors

D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons. Science (1990) 8.07

Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol Cell Biol (1995) 7.12

Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain. Immunity (1995) 7.08

Myocardial infarct size and ventricular function in rats. Circ Res (1979) 4.33

Defects in enteric innervation and kidney development in mice lacking GDNF. Nature (1996) 3.82

Regulation of transmembrane signaling by receptor phosphorylation. Cell (1987) 3.74

Molecular mechanisms of receptor desensitization using the beta-adrenergic receptor-coupled adenylate cyclase system as a model. Nature (1985) 3.74

Isolation of cDNA clones coding for the beta subunit of human beta-hexosaminidase. Proc Natl Acad Sci U S A (1985) 3.50

Early neonatal death in mice homozygous for a null allele of the insulin receptor gene. Nat Genet (1996) 3.40

Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties. J Biol Chem (2000) 3.22

Characterization of the human cysteinyl leukotriene 2 receptor. J Biol Chem (2000) 2.89

Lhx2, a LIM homeobox gene, is required for eye, forebrain, and definitive erythrocyte development. Development (1997) 2.66

A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11. Gene (1993) 2.59

Isolation of cDNA clones coding for the alpha-subunit of human beta-hexosaminidase. Extensive homology between the alpha- and beta-subunits and studies on Tay-Sachs disease. J Biol Chem (1986) 2.54

The Concise Guide to PHARMACOLOGY 2013/14: overview. Br J Pharmacol (2013) 2.48

Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1. Nature (1991) 2.41

Progressive ventricular remodeling in rat with myocardial infarction. Am J Physiol (1991) 2.40

Cardiac event recorders yield more diagnoses and are more cost-effective than 48-hour Holter monitoring in patients with palpitations. A controlled clinical trial. Ann Intern Med (1996) 2.27

Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J Pharmacol Exp Ther (1994) 2.27

Cross-talk between cellular signalling pathways suggested by phorbol-ester-induced adenylate cyclase phosphorylation. Nature (1987) 2.16

Characterization of apelin, the ligand for the APJ receptor. J Neurochem (2000) 2.11

Phosphorylation sites on two domains of the beta 2-adrenergic receptor are involved in distinct pathways of receptor desensitization. J Biol Chem (1989) 2.10

Discovery of a receptor related to the galanin receptors. FEBS Lett (1999) 2.01

Reinstatement of alcohol-seeking by priming injections of alcohol and exposure to stress in rats. Psychopharmacology (Berl) (1998) 1.94

Removal of phosphorylation sites from the beta 2-adrenergic receptor delays onset of agonist-promoted desensitization. Nature (1988) 1.88

Molecular cloning and expression of a D1 dopamine receptor linked to adenylyl cyclase activation. Proc Natl Acad Sci U S A (1990) 1.87

Multiple D2 dopamine receptors produced by alternative RNA splicing. Nature (1990) 1.84

Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype. J Biol Chem (1993) 1.84

Phenotypic characterization of an alpha 4 neuronal nicotinic acetylcholine receptor subunit knock-out mouse. J Neurosci (2000) 1.70

Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain. Brain Res Mol Brain Res (1999) 1.68

The effect of digital rectal examination on prostate-specific antigen levels. JAMA (1992) 1.66

Characterization of a novel sphingosine 1-phosphate receptor, Edg-8. J Biol Chem (2000) 1.63

Interactions of the novel antipsychotic aripiprazole (OPC-14597) with dopamine and serotonin receptor subtypes. Neuropsychopharmacology (1999) 1.60

Discovery and mapping of ten novel G protein-coupled receptor genes. Gene (2001) 1.60

Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs. Mol Pharmacol (1993) 1.59

Left ventricular diastolic pressure-volume relations in rats with healed myocardial infarction. Effects on systolic function. Circ Res (1981) 1.55

D1 and D2 dopamine receptor mRNA in rat brain. Proc Natl Acad Sci U S A (1991) 1.55

Gene targeting of Desrt, a novel ARID class DNA-binding protein, causes growth retardation and abnormal development of reproductive organs. Genome Res (2001) 1.53

Cloning and expression of an A1 adenosine receptor from rat brain. Mol Pharmacol (1991) 1.51

Discovery of three novel G-protein-coupled receptor genes. Genomics (1998) 1.50

A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1. Biochem Biophys Res Commun (1997) 1.50

A targeted mutation of the D3 dopamine receptor gene is associated with hyperactivity in mice. Proc Natl Acad Sci U S A (1996) 1.48

Phosphorylation/dephosphorylation of the beta-adrenergic receptor regulates its functional coupling to adenylate cyclase and subcellular distribution. Proc Natl Acad Sci U S A (1986) 1.46

Two distinct pathways for cAMP-mediated down-regulation of the beta 2-adrenergic receptor. Phosphorylation of the receptor and regulation of its mRNA level. J Biol Chem (1989) 1.45

The role of corticotropin-releasing factor in the median raphe nucleus in relapse to alcohol. J Neurosci (2002) 1.42

Homologous desensitization of adenylate cyclase is associated with phosphorylation of the beta-adrenergic receptor. J Biol Chem (1985) 1.41

Discovery of a novel member of the histamine receptor family. Mol Pharmacol (2001) 1.41

Molecular cloning of a novel G protein-coupled receptor related to the opiate receptor family. J Neurochem (1995) 1.40

The American Cancer Society National Prostate Cancer Detection Project. Findings on the detection of early prostate cancer in 2425 men. Cancer (1991) 1.39

Cloning, expression, and chromosomal localization of the human uridine nucleotide receptor gene. J Biol Chem (1995) 1.39

Sotalol proarrhythmia: a report of five cases and an audit of the use of a sotalol in a teaching hospital. Aust N Z J Med (1996) 1.38

Desensitization of turkey erythrocyte adenylate cyclase. Beta-adrenergic receptor phosphorylation is correlated with attenuation of adenylate cyclase activity. J Biol Chem (1984) 1.38

Molecular cloning and characterization of a lysophosphatidic acid receptor, Edg-7, expressed in prostate. Mol Pharmacol (2000) 1.37

Effect of nasal continuous positive airway pressure during sleep on 24-hour blood pressure in obstructive sleep apnea. Sleep (1993) 1.37

Phorbol diesters promote beta-adrenergic receptor phosphorylation and adenylate cyclase desensitization in duck erythrocytes. Biochem Biophys Res Commun (1984) 1.37

Reduced fear and aggression and altered serotonin metabolism in Gtf2ird1-targeted mice. Genes Brain Behav (2007) 1.37

Role of the D1A dopamine receptor in the pathogenesis of genetic hypertension. J Clin Invest (1996) 1.34

The amphetamine-induced sensitized state as a model of schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry (2007) 1.34

Mice homozygous for an insertional mutation in the Zp3 gene lack a zona pellucida and are infertile. Development (1996) 1.33

Fibroblast growth factor stimulates the proliferation and differentiation of neural precursor cells in vitro. J Neurosci Res (1990) 1.32

Identification of a molecular target of psychosine and its role in globoid cell formation. J Cell Biol (2001) 1.32

The classification of dopamine receptors: relationship to radioligand binding. Annu Rev Neurosci (1983) 1.32

Identification of urotensin II as the endogenous ligand for the orphan G-protein-coupled receptor GPR14. Biochem Biophys Res Commun (1999) 1.32

Expression of striatal D1 dopamine receptors coupled to inositol phosphate production and Ca2+ mobilization in Xenopus oocytes. Proc Natl Acad Sci U S A (1990) 1.27

Cloning of human genes encoding novel G protein-coupled receptors. Genomics (1994) 1.26

Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor. J Neurochem (1996) 1.26

A single amino-acid difference confers major pharmacological variation between human and rodent 5-HT1B receptors. Nature (1992) 1.26

Retained cocaine conditioned place preference in D1 receptor deficient mice. Neuroreport (1995) 1.23

Anterior pituitary dopamine receptors. Demonstration of interconvertible high and low affinity states of the D-2 dopamine receptor. J Biol Chem (1982) 1.23

A novel catecholamine-activated adenosine cyclic 3',5'-phosphate independent pathway for beta-adrenergic receptor phosphorylation in wild-type and mutant S49 lymphoma cells: mechanism of homologous desensitization of adenylate cyclase. Biochemistry (1986) 1.23

Behavioral characterization of dopamine D5 receptor null mutant mice. Behav Neurosci (2001) 1.22

Receptor adaptations to centrally acting drugs. Annu Rev Pharmacol Toxicol (1981) 1.22

Studies to investigate the role of 5-HT(2C) receptors on cocaine- and food-maintained behavior. J Pharmacol Exp Ther (2000) 1.21

FMRFamide-related neuropeptides are agonists of the orphan G-protein-coupled receptor GPR54. Biochem Biophys Res Commun (2001) 1.20

Desensitization, phosphorylation and palmitoylation of the human dopamine D1 receptor. Eur J Pharmacol (1994) 1.20

Neuropathologic features in adults with 22q11.2 deletion syndrome. Cereb Cortex (2008) 1.19

Dopamine D2 receptor dimers and receptor-blocking peptides. Biochem Biophys Res Commun (1996) 1.18

Molecular heterogeneity in the infantile and juvenile forms of Sandhoff disease (O-variant GM2 gangliosidosis). J Biol Chem (1986) 1.18

Modulatory actions of dopamine on NMDA receptor-mediated responses are reduced in D1A-deficient mutant mice. J Neurosci (1996) 1.17

Polymorphisms of the D4 dopamine receptor alleles in chronic alcoholism. Biochem Biophys Res Commun (1993) 1.17

The role of phosphorylation/dephosphorylation in agonist-induced desensitization of D1 dopamine receptor function: evidence for a novel pathway for receptor dephosphorylation. Mol Pharmacol (2001) 1.17

Disruption of dopamine D1 receptor gene expression attenuates alcohol-seeking behavior. Eur J Pharmacol (1998) 1.14