Published in Mol Cell Biol on January 01, 2000
Regulation of CD45 alternative splicing by heterogeneous ribonucleoprotein, hnRNPLL. Science (2008) 3.17
Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy. Cancer Discov (2015) 2.29
HnRNP L represses exon splicing via a regulated exonic splicing silencer. EMBO J (2005) 2.20
Memory T cell RNA rearrangement programmed by heterogeneous nuclear ribonucleoprotein hnRNPLL. Immunity (2008) 2.13
Global analysis of alternative splicing during T-cell activation. RNA (2007) 2.11
Regulation of alternative pre-mRNA splicing by the ERK MAP-kinase pathway. EMBO J (2001) 1.83
The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus. Mol Cell (2012) 1.83
A cell-based screen for splicing regulators identifies hnRNP LL as a distinct signal-induced repressor of CD45 variable exon 4. RNA (2008) 1.82
Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases. J Clin Invest (2002) 1.78
CD45, CD148, and Lyp/Pep: critical phosphatases regulating Src family kinase signaling networks in immune cells. Immunol Rev (2009) 1.73
Regulation of vascular endothelial growth factor (VEGF) splicing from pro-angiogenic to anti-angiogenic isoforms: a novel therapeutic strategy for angiogenesis. J Biol Chem (2009) 1.68
Combinatorial control of signal-induced exon repression by hnRNP L and PSF. Mol Cell Biol (2007) 1.62
Degrade, move, regroup: signaling control of splicing proteins. Trends Biochem Sci (2011) 1.32
Phosphorylation-dependent regulation of PSF by GSK3 controls CD45 alternative splicing. Mol Cell (2010) 1.30
An optogenetic gene expression system with rapid activation and deactivation kinetics. Nat Chem Biol (2014) 1.30
A consensus CaMK IV-responsive RNA sequence mediates regulation of alternative exons in neurons. RNA (2005) 1.19
Control of alternative splicing in immune responses: many regulators, many predictions, much still to learn. Immunol Rev (2013) 1.14
Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling. J Exp Med (2000) 1.11
Dual utilization of an acceptor/donor splice site governs the alternative splicing of the IRF-3 gene. Genes Dev (2000) 1.11
Protein kinase C-dependent control of Bcl-x alternative splicing. Mol Cell Biol (2007) 1.10
Signal- and development-dependent alternative splicing of LEF1 in T cells is controlled by CELF2. Mol Cell Biol (2011) 1.06
Use of transcriptional synergy to augment sensitivity of a splicing reporter assay. RNA (2006) 1.04
Alternative splicing networks regulated by signaling in human T cells. RNA (2012) 1.03
The impact of alternative splicing in vivo: mouse models show the way. RNA (2007) 1.03
HnRNP L and L-like cooperate in multiple-exon regulation of CD45 alternative splicing. Nucleic Acids Res (2012) 0.98
A disease-associated polymorphism alters splicing of the human CD45 phosphatase gene by disrupting combinatorial repression by heterogeneous nuclear ribonucleoproteins (hnRNPs). J Biol Chem (2011) 0.97
Global analysis of alternative splicing regulation by insulin and wingless signaling in Drosophila cells. Genome Biol (2009) 0.96
Control of alternative pre-mRNA splicing by Ca(++) signals. Biochim Biophys Acta (2008) 0.95
Induced transcription and stability of CELF2 mRNA drives widespread alternative splicing during T-cell signaling. Proc Natl Acad Sci U S A (2015) 0.94
Identification of cells deficient in signaling-induced alternative splicing by use of somatic cell genetics. RNA (2002) 0.92
Transcriptome-wide RNA interaction profiling reveals physical and functional targets of hnRNP L in human T cells. Mol Cell Biol (2013) 0.90
Identification of Anti-tumor Cells Carrying Natural Killer (NK) Cell Antigens in Patients With Hematological Cancers. EBioMedicine (2015) 0.86
Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation. Genes Dev (2015) 0.86
The signaling symphony: T cell receptor tunes cytokine-mediated T cell differentiation. J Leukoc Biol (2014) 0.84
A new view of transcriptome complexity and regulation through the lens of local splicing variations. Elife (2016) 0.84
PSF controls expression of histone variants and cellular viability in thymocytes. Biochem Biophys Res Commun (2011) 0.83
Bipartite functions of the CREB co-activators selectively direct alternative splicing or transcriptional activation. EMBO J (2009) 0.81
Activation-induced tumor necrosis factor receptor-associated factor 3 (Traf3) alternative splicing controls the noncanonical nuclear factor κB pathway and chemokine expression in human T cells. J Biol Chem (2014) 0.80
Protein kinase WNK3 regulates the neuronal splicing factor Fox-1. Proc Natl Acad Sci U S A (2012) 0.79
Paralogs hnRNP L and hnRNP LL exhibit overlapping but distinct RNA binding constraints. PLoS One (2013) 0.78
TRAP150 interacts with the RNA-binding domain of PSF and antagonizes splicing of numerous PSF-target genes in T cells. Nucleic Acids Res (2015) 0.78
Position-dependent activity of CELF2 in the regulation of splicing and implications for signal-responsive regulation in T cells. RNA Biol (2016) 0.77
Mechano-regulation of alternative splicing. Curr Genomics (2013) 0.77
The Role of Alternative Splicing in the Control of Immune Homeostasis and Cellular Differentiation. Int J Mol Sci (2015) 0.76
PKC-Theta is a Novel SC35 Splicing Factor Regulator in Response to T Cell Activation. Front Immunol (2015) 0.75
Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. J Biol Chem (1982) 16.71
pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res (1990) 12.75
Signal transduction by lymphocyte antigen receptors. Cell (1994) 10.63
Exon recognition in vertebrate splicing. J Biol Chem (1995) 10.08
The superfamily of arginine/serine-rich splicing factors. RNA (1995) 7.96
Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells. J Immunol (1988) 7.37
SR proteins and splicing control. Genes Dev (1996) 7.09
Stimulation of p21ras upon T-cell activation. Nature (1990) 5.72
Finding splice sites within a wilderness of RNA. RNA (1995) 4.35
Interconversion of CD45R subsets of CD4 T cells in vivo. Nature (1990) 4.27
Activation of extracellular signal-regulated kinase, ERK2, by p21ras oncoprotein. EMBO J (1992) 4.00
Signal transmission between the plasma membrane and nucleus of T lymphocytes. Annu Rev Biochem (1994) 4.00
Identification and characterization of three members of the human SR family of pre-mRNA splicing factors. EMBO J (1995) 3.56
CD45: an emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development. Annu Rev Immunol (1994) 3.50
Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens. J Exp Med (1987) 3.14
T cell antigen receptor signal transduction pathways. Annu Rev Immunol (1996) 3.11
Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice. Cell (1993) 3.07
Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines. Proc Natl Acad Sci U S A (1989) 2.99
Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway. Nature (1990) 2.51
Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production. Proc Natl Acad Sci U S A (1991) 2.45
Regulation of tissue-specific alternative splicing: exon-specific cis-elements govern the splicing of leukocyte common antigen pre-mRNA. EMBO J (1989) 2.41
Activation of a human T cell line: a two-stimulus requirement in the pretranslational events involved in the coordinate expression of interleukin 2 and gamma-interferon genes. J Immunol (1985) 2.39
Control of alternative splicing of potassium channels by stress hormones. Science (1998) 2.35
Signal transduction from multiple Ras effectors. Curr Opin Genet Dev (1997) 2.16
Changes in CD45 isoform expression accompany antigen-induced murine T-cell activation. Proc Natl Acad Sci U S A (1989) 2.15
Function of Ras as a molecular switch in signal transduction. J Biol Chem (1992) 2.08
Biochemistry and regulation of pre-mRNA splicing. Curr Opin Cell Biol (1996) 1.98
Splicing regulation in neurons: tinkering with cell-specific control. Cell (1998) 1.96
Coupling of signal transduction to alternative pre-mRNA splicing by a composite splice regulator. EMBO J (1998) 1.93
Common themes in the function of transcription and splicing enhancers. Curr Opin Cell Biol (1997) 1.92
A functional T-cell receptor signaling pathway is required for p95vav activity. Mol Cell Biol (1995) 1.88
Cytoskeletal polarization of T cells is regulated by an immunoreceptor tyrosine-based activation motif-dependent mechanism. J Cell Biol (1998) 1.85
Involvement of p21ras activation in T cell CD69 expression. Eur J Immunol (1994) 1.85
CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation. J Exp Med (1996) 1.83
Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase. Cell (1993) 1.78
Cyclic regulation of CD45 isoform expression in a long term human CD4+CD45RA+ T cell line. J Immunol (1991) 1.75
Regulation of pre-mRNA splicing in metazoa. Curr Opin Genet Dev (1997) 1.59
LARD: a new lymphoid-specific death domain containing receptor regulated by alternative pre-mRNA splicing. Proc Natl Acad Sci U S A (1997) 1.58
c-rel regulation of IL-2 gene expression may be mediated through activation of AP-1. J Exp Med (1996) 1.57
Correlation between Src family member regulation by the protein-tyrosine-phosphatase CD45 and transmembrane signaling through the T-cell receptor. Proc Natl Acad Sci U S A (1993) 1.54
Dimerization-induced inhibition of receptor protein tyrosine phosphatase function through an inhibitory wedge. Science (1998) 1.52
CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck. EMBO J (1993) 1.37
CD45. A prototype for transmembrane protein tyrosine phosphatases. J Biol Chem (1991) 1.33
A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK. EMBO J (1998) 1.31
Coclustering CD45 with CD4 or CD8 alters the phosphorylation and kinase activity of p56lck. J Exp Med (1990) 1.23
The extracellular domain of CD45 controls association with the CD4-T cell receptor complex and the response to antigen-specific stimulation. J Exp Med (1996) 1.16
SF2 and SRp55 regulation of CD45 exon 4 skipping during T cell activation. Eur J Immunol (1999) 1.14
Integrity of the exon 6 sequence is essential for tissue-specific alternative splicing of human leukocyte common antigen pre-mRNA. Mol Cell Biol (1989) 1.12
Restoration of T cell receptor-mediated signal transduction by transfection of CD45 cDNA into a CD45-deficient variant of the Jurkat T cell line. J Immunol (1992) 1.10
Regulation of insulin preRNA splicing by glucose. Proc Natl Acad Sci U S A (1997) 1.10
Aberrant TCR-mediated signaling in CD45-null thymocytes involves dysfunctional regulation of Lck, Fyn, TCR-zeta, and ZAP-70. J Immunol (1997) 1.09
The alternative splicing of the CD45 tyrosine phosphatase is controlled by negative regulatory trans-acting splicing factors. J Biol Chem (1992) 1.08
A point mutation in the human CD45 gene associated with defective splicing of exon A. Eur J Immunol (1995) 1.08
Expression of soluble isoforms of rat CD45. Analysis by electron microscopy and use in epitope mapping of anti-CD45R monoclonal antibodies. Immunology (1992) 1.07
Differential expression of human Fas mRNA species upon peripheral blood mononuclear cell activation. Biochem J (1995) 1.02
The mammalian homolog of suppressor-of-white-apricot regulates alternative mRNA splicing of CD45 exon 4 and fibronectin IIICS. J Biol Chem (1996) 0.98
Insulin regulates protein kinase CbetaII expression through enhanced exon inclusion in L6 skeletal muscle cells. A novel mechanism of insulin- and insulin-like growth factor-i-induced 5' splice site selection. J Biol Chem (1998) 0.97
Expression of the p56(Lck) Y505F mutation in CD45-deficient mice rescues thymocyte development. Mol Cell Biol (1999) 0.97
Biochemical association of CD45 with the T cell receptor complex: regulation by CD45 isoform and during T cell activation. Immunity (1999) 0.95
Effect of activation of protein kinase C on CD45 isoform expression and CD45 protein tyrosine phosphatase activity in T cells. Eur J Immunol (1990) 0.91
A point mutation within CD45 exon A is the cause of variant CD45RA splicing in humans. Eur J Immunol (1998) 0.87
An analysis of alternatively spliced CD45 mRNA transcripts during T cell maturation in humans. Cell Immunol (1997) 0.85
Phenotypical and biochemical characterization of a variant CD45R expression pattern in human leukocytes. Eur J Immunol (1992) 0.83
Transient accumulation and subsequent rapid loss of messenger RNA encoding high molecular mass CD45 isoforms after T cell activation. J Immunol (1992) 0.83
Selective regulation of agrin mRNA induction and alternative splicing in PC12 cells by Ras-dependent actions of nerve growth factor. J Biol Chem (1997) 0.83
Regulation of alternative splicing in the generation of isoforms of the mouse Ly-5 (CD45) glycoprotein. Proc Natl Acad Sci U S A (1990) 0.82
Further data on the selective expression of Ly-5 isoforms. Immunogenetics (1990) 0.79
Polarity of Tn5 insertion mutations in Escherichia coli. J Bacteriol (1980) 7.55
The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways. Cell (1991) 6.13
The role of T3 surface molecules in the activation of human T cells: a two-stimulus requirement for IL 2 production reflects events occurring at a pre-translational level. J Immunol (1984) 5.80
The role of the T3/antigen receptor complex in T-cell activation. Annu Rev Immunol (1986) 5.67
ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain. Cell (1992) 5.53
Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line. J Exp Med (1984) 5.26
Regulation of interleukin-2 gene enhancer activity by the T cell accessory molecule CD28. Science (1991) 5.12
Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor. Cell (1992) 5.08
Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium. Proc Natl Acad Sci U S A (1984) 4.66
In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers. J Exp Med (2000) 4.37
Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases. Science (1994) 4.23
Induction of NF-kappaB by the Akt/PKB kinase. Curr Biol (1999) 4.03
Characterization of two adhesins of Bordetella pertussis for human ciliated respiratory-epithelial cells. J Infect Dis (1985) 3.66
LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway. Immunity (1998) 3.36
The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction. Annu Rev Immunol (1994) 3.35
Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs. Nature (1992) 3.02
Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell. Science (1998) 2.93
The trans-neptunian object UB313 is larger than Pluto. Nature (2006) 2.88
Signal transduction by the TCR for antigen. Curr Opin Immunol (2000) 2.87
Urinary leukocyte esterase screening test for asymptomatic chlamydial and gonococcal infections in males. JAMA (1989) 2.87
Reconstitution of an active surface T3/T-cell antigen receptor by DNA transfer. Nature (1985) 2.84
The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein. Proc Natl Acad Sci U S A (1991) 2.74
Expression of T3 in association with a molecule distinct from the T-cell antigen receptor heterodimer. Proc Natl Acad Sci U S A (1986) 2.73
ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency. Science (1994) 2.71
Antigen cap formation in cultured fibroblasts: a reflection of membrane fluidity and of cell motility. Proc Natl Acad Sci U S A (1972) 2.71
Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase. Science (1994) 2.70
PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression. J Biol Chem (2000) 2.57
Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines. Nat Immunol (2001) 2.55
The T cell antigen receptor complex expressed on normal peripheral blood CD4-, CD8- T lymphocytes. A CD3-associated disulfide-linked gamma chain heterodimer. J Exp Med (1987) 2.52
Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway. Nature (1990) 2.51
Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production. Proc Natl Acad Sci U S A (1991) 2.45
Activation of a human T cell line: a two-stimulus requirement in the pretranslational events involved in the coordinate expression of interleukin 2 and gamma-interferon genes. J Immunol (1985) 2.39
Expression and function of the CD3-antigen receptor on murine CD4+8+ thymocytes. Nature (1987) 2.38
A 275 basepair fragment at the 5' end of the interleukin 2 gene enhances expression from a heterologous promoter in response to signals from the T cell antigen receptor. J Exp Med (1987) 2.37
Distinct subsets of CD1d-restricted T cells recognize self-antigens loaded in different cellular compartments. J Exp Med (1999) 2.23
The immunological synapse and CD28-CD80 interactions. Nat Immunol (2001) 2.23
Presence of Ti (WT31) negative T lymphocytes in normal blood and thymus. Nature (1987) 2.20
Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation. Immunity (1996) 2.18
Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain. J Exp Med (1993) 2.17
Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site. Proc Natl Acad Sci U S A (1998) 2.16
The antigen receptor on a human T cell line initiates activation by increasing cytoplasmic free calcium. J Immunol (1985) 2.13
Specific antigen-Ia activation of transfected human T cells expressing murine Ti alpha beta-human T3 receptor complexes. Nature (1987) 2.11
An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity. Cell (2000) 2.00
Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes. J Exp Med (1996) 1.98
T cell activation: differences in the signals required for IL 2 production by nonactivated and activated T cells. J Immunol (1985) 1.94
T cell antigen receptor signal transduction. Curr Opin Cell Biol (1997) 1.92
Recovery of Bordetella pertussis from four kinds of swabs. Eur J Clin Microbiol (1987) 1.89
ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR zeta in murine thymocytes and lymph node T cells. Immunity (1994) 1.88
A functional T-cell receptor signaling pathway is required for p95vav activity. Mol Cell Biol (1995) 1.88
Cytoskeletal polarization of T cells is regulated by an immunoreceptor tyrosine-based activation motif-dependent mechanism. J Cell Biol (1998) 1.85
Early signal transduction by the antigen receptor without commitment to T cell activation. Science (1988) 1.85
The mouse CD1d-restricted repertoire is dominated by a few autoreactive T cell receptor families. J Exp Med (2001) 1.85
CD28 mediates transcriptional upregulation of the interleukin-2 (IL-2) promoter through a composite element containing the CD28RE and NF-IL-2B AP-1 sites. Mol Cell Biol (1997) 1.83
Identification of the minimal tyrosine residues required for linker for activation of T cell function. J Biol Chem (2001) 1.81
The Syk family of protein tyrosine kinases in T-cell activation and development. Immunol Rev (1998) 1.81
Identification and sequence of a fourth human T cell antigen receptor chain. Nature (1988) 1.81
Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling. J Immunol (1994) 1.80
alpha beta T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases. Immunity (1996) 1.79
Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase. Cell (1993) 1.78
T cell receptor signalling. J Cell Sci (2001) 1.74
GRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation. Mol Cell Biol (1994) 1.71
Synergy between the T3/antigen receptor complex and Tp44 in the activation of human T cells. J Immunol (1986) 1.70
The role of protein kinase C in transmembrane signaling by the T cell antigen receptor complex. Effects of stimulation with soluble or immobilized CD3 antibodies. J Immunol (1987) 1.70
Treatment of Adult ALL according to protocols of the German Multicenter Study Group for Adult ALL (GMALL). Hematol Oncol Clin North Am (2000) 1.69
Reduced α-synuclein levels in cerebrospinal fluid in Parkinson's disease are unrelated to clinical and imaging measures of disease severity. Eur J Neurol (2013) 1.69
Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFAT. Mol Cell Biol (2001) 1.69
GLUT1 glucose transporter expression in colorectal carcinoma: a marker for poor prognosis. Cancer (1998) 1.68
The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3'-kinase. Mol Cell Biol (1994) 1.67
Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling. J Exp Med (1997) 1.67
A randomized comparison of assisted vaginal delivery by obstetric forceps and polyethylene vacuum cup. Obstet Gynecol (1991) 1.65
Ligand-receptor interactions required for commitment to the activation of the interleukin 2 gene. J Immunol (1987) 1.62
Tetracycline-controllable selection of CD4(+) T cells: half-life and survival signals in the absence of major histocompatibility complex class II molecules. J Exp Med (2000) 1.61
Polyuridylic acid binding and translating by Escherichia coli ribosomes: stimulation by protein I, inhibition by aurintricarboxylic acid. Biochim Biophys Acta (1972) 1.60
c-rel regulation of IL-2 gene expression may be mediated through activation of AP-1. J Exp Med (1996) 1.57
Isolation and characterization of a T-lymphocyte somatic mutant with altered signal transduction by the antigen receptor. Proc Natl Acad Sci U S A (1987) 1.57
Deregulated signal transduction by the K1 gene product of Kaposi's sarcoma-associated herpesvirus. Proc Natl Acad Sci U S A (1999) 1.57
T-lymphocyte-antigen interactions in transplant rejection. N Engl J Med (1990) 1.55
Antiproliferative action of interferon-alpha requires components of T-cell-receptor signalling. Nature (1997) 1.54
Traumatic retinoschisis in battered babies. Ophthalmology (1986) 1.52
Dimerization-induced inhibition of receptor protein tyrosine phosphatase function through an inhibitory wedge. Science (1998) 1.52
Phosphotyrosines in the killer cell inhibitory receptor motif of NKB1 are required for negative signaling and for association with protein tyrosine phosphatase 1C. J Exp Med (1996) 1.50
Flow cytometry--principles and feasibility in transfusion medicine. Enumeration of epithelial derived tumor cells in peripheral blood. Vox Sang (1998) 1.49
The CD2 ligand LFA-3 activates T cells but depends on the expression and function of the antigen receptor. J Immunol (1988) 1.49
The protein tyrosine kinase ZAP-70 can associate with the SH2 domain of proto-Vav. J Biol Chem (1994) 1.45
A comparison of total intravenous with balanced anaesthesia for middle ear surgery: effects on postoperative nausea and vomiting, pain, and conditions of surgery. Anaesthesia (2003) 1.45
Thy-1-mediated T-cell activation requires co-expression of CD3/Ti complex. Nature (1987) 1.41
Stimulation of the phosphatidylinositol pathway can induce T-cell activation. Nature (1990) 1.41
Delta is the Cx-gene product in the gamma/delta antigen receptor of dendritic epidermal cells. Nature (1988) 1.41
The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase. Mol Cell Biol (2000) 1.40
Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling. J Exp Med (1996) 1.39
"Congenital" coronary arteriovenous malformations: are they truly congenital? Cathet Cardiovasc Diagn (1996) 1.39
Filamentous hemagglutinin and pertussis toxin promote adherence of Bordetella pertussis to cilia. Dev Biol Stand (1985) 1.39
Accumulation of a right ventricular mass during shoulder hemiarthroplasty. Anesth Analg (1995) 1.38
Localization of LAT in glycolipid-enriched microdomains is required for T cell activation. J Biol Chem (1999) 1.38
CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck. EMBO J (1993) 1.37
CD28 and T cell antigen receptor signal transduction coordinately regulate interleukin 2 gene expression in response to superantigen stimulation. J Exp Med (1992) 1.36
Molecular cloning of human Syk. A B cell protein-tyrosine kinase associated with the surface immunoglobulin M-B cell receptor complex. J Biol Chem (1994) 1.35
Anaphylaxis due to propofol. Anesthesiology (1992) 1.35
SH2 domain function is essential for the role of the Lck tyrosine kinase in T cell receptor signal transduction. J Biol Chem (1996) 1.33
ESE-3, a novel member of an epithelium-specific ets transcription factor subfamily, demonstrates different target gene specificity from ESE-1. J Biol Chem (2000) 1.33