Published in J Exp Med on July 01, 1996
A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells. J Exp Med (1997) 3.57
PD-1 signaling in primary T cells. Immunol Rev (2009) 2.66
Negative signaling by inhibitory receptors: the NK cell paradigm. Immunol Rev (2008) 2.40
A novel pair of immunoglobulin-like receptors expressed by B cells and myeloid cells. Proc Natl Acad Sci U S A (1997) 2.11
A novel inhibitory receptor (ILT3) expressed on monocytes, macrophages, and dendritic cells involved in antigen processing. J Exp Med (1997) 2.05
Identification of major binding proteins and substrates for the SH2-containing protein tyrosine phosphatase SHP-1 in macrophages. Mol Cell Biol (1998) 1.61
Microclusters of inhibitory killer immunoglobulin-like receptor signaling at natural killer cell immunological synapses. J Cell Biol (2006) 1.42
A balance between positive and negative signals in cytotoxic lymphocytes regulates the polarization of lipid rafts during the development of cell-mediated killing. J Exp Med (2000) 1.39
Mouse Ly-49A interrupts early signaling events in natural killer cell cytotoxicity and functionally associates with the SHP-1 tyrosine phosphatase. J Exp Med (1997) 1.37
NKG2A complexed with CD94 defines a novel inhibitory natural killer cell receptor. J Exp Med (1997) 1.35
Self and viral peptides can initiate lysis by autologous natural killer cells. Proc Natl Acad Sci U S A (1997) 1.29
Functional role for Syk tyrosine kinase in natural killer cell-mediated natural cytotoxicity. J Exp Med (1997) 1.18
Killer cell inhibitory receptor recognition of human leukocyte antigen (HLA) class I blocks formation of a pp36/PLC-gamma signaling complex in human natural killer (NK) cells. J Exp Med (1996) 1.17
Inhibitory receptors alter natural killer cell interactions with target cells yet allow simultaneous killing of susceptible targets. J Exp Med (1999) 1.17
Improving the outcome of leukemia by natural killer cell-based immunotherapeutic strategies. Front Immunol (2014) 1.10
Developmentally regulated extinction of Ly-49 receptor expression permits maturation and selection of NK1.1+ T cells. J Exp Med (1998) 1.08
Negative signaling pathways of the killer cell inhibitory receptor and Fc gamma RIIb1 require distinct phosphatases. J Exp Med (1997) 0.99
Natural killer activating receptors trigger interferon gamma secretion from T cells and natural killer cells. Proc Natl Acad Sci U S A (1998) 0.97
Genetic control of natural killing and in vivo tumor elimination by the Chok locus. J Exp Med (1998) 0.90
The mother-child union: the case of missing-self and protection of the fetus. Proc Natl Acad Sci U S A (1997) 0.88
Revving up Natural Killer Cells and Cytokine-Induced Killer Cells Against Hematological Malignancies. Front Immunol (2015) 0.88
The lectin-like receptor KLRE1 inhibits natural killer cell cytotoxicity. J Exp Med (2003) 0.86
Natural killer cell acceptance of H-2 mismatch bone marrow grafts in transgenic mice expressing HLA-Cw3 specific killer cell inhibitory receptor. Proc Natl Acad Sci U S A (1997) 0.86
SHP-2 expression negatively regulates NK cell function. J Immunol (2009) 0.85
A peptide antagonist disrupts NK cell inhibitory synapse formation. J Immunol (2013) 0.83
KIR2DL4 copy number variation is associated with CD4+ T-cell depletion and function of cytokine-producing NK cell subsets in SIV-infected Mamu-A*01-negative rhesus macaques. J Virol (2013) 0.80
The Size of Activating and Inhibitory Killer Ig-like Receptor Nanoclusters Is Controlled by the Transmembrane Sequence and Affects Signaling. Cell Rep (2016) 0.79
SHP-1/immunoreceptor tyrosine-based inhibition motif-independent inhibitory signalling through murine natural killer cell receptor Ly-49A in a transfected B-cell line. Immunology (2000) 0.76
Resurrecting KIR2DP1: A Key Intermediate in the Evolution of Human Inhibitory NK Cell Receptors That Recognize HLA-C. J Immunol (2017) 0.76
H-2Dd engagement of Ly49A leads directly to Ly49A phosphorylation and recruitment of SHP1. Immunology (1999) 0.75
The immunomodulating roles of glycoproteins in epithelial ovarian cancer. Front Biosci (Elite Ed) (2012) 0.75
Retracted Alloreactivity and association of human natural killer cells with the major histocompatibility complex. Clin Diagn Lab Immunol (1999) 0.75
Current perspectives on natural killer cell education and tolerance: emerging roles for inhibitory receptors. Immunotargets Ther (2015) 0.75
Signal transduction by lymphocyte antigen receptors. Cell (1994) 10.63
Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells. Science (1995) 5.41
Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line. J Exp Med (1984) 5.26
Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals. Cell (1995) 4.32
Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases. Science (1994) 4.23
Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene. Cell (1993) 4.06
Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains. Immunity (1995) 3.72
Recruitment of tyrosine phosphatase HCP by the killer cell inhibitor receptor. Immunity (1996) 3.33
T cell antigen receptor signal transduction: a tale of tails and cytoplasmic protein-tyrosine kinases. Cell (1993) 3.25
Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by Fc gamma RIIB1. Science (1995) 3.24
Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene. Nat Genet (1993) 3.11
Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor. Nature (1995) 2.79
The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein. Proc Natl Acad Sci U S A (1991) 2.74
A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP. Science (1995) 2.68
Molecular cloning of NKB1. A natural killer cell receptor for HLA-B allotypes. J Immunol (1995) 2.63
Superantigen-dependent, cell-mediated cytotoxicity inhibited by MHC class I receptors on T lymphocytes. Science (1995) 2.44
Inhibitory MHC class I receptors on NK cells and T cells. Immunol Today (1996) 2.42
Protein tyrosine phosphatases. Annu Rev Biochem (1993) 2.37
Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain. J Exp Med (1993) 2.17
Expression and catalytic activity of the tyrosine phosphatase PTP1C is severely impaired in motheaten and viable motheaten mice. J Exp Med (1993) 1.95
A functional T-cell receptor signaling pathway is required for p95vav activity. Mol Cell Biol (1995) 1.88
Hematopoietic cell phosphatase associates with the interleukin-3 (IL-3) receptor beta chain and down-regulates IL-3-induced tyrosine phosphorylation and mitogenesis. Mol Cell Biol (1993) 1.86
Association of hematopoietic cell phosphatase with c-Kit after stimulation with c-Kit ligand. Mol Cell Biol (1993) 1.84
Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2. Nature (1996) 1.65
Activation of human peripheral blood T lymphocytes by pharmacological induction of protein-tyrosine phosphorylation. Proc Natl Acad Sci U S A (1992) 1.55
Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science (1999) 11.04
Polymerase chain reaction with single-sided specificity: analysis of T cell receptor delta chain. Science (1989) 9.01
Polarity of Tn5 insertion mutations in Escherichia coli. J Bacteriol (1980) 7.55
HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature (1998) 7.12
Subpopulations of human natural killer cells defined by expression of the Leu-7 (HNK-1) and Leu-11 (NK-15) antigens. J Immunol (1983) 6.39
The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways. Cell (1991) 6.13
Immune inhibitory receptors. Science (2000) 6.05
The role of T3 surface molecules in the activation of human T cells: a two-stimulus requirement for IL 2 production reflects events occurring at a pre-translational level. J Immunol (1984) 5.80
The role of the T3/antigen receptor complex in T-cell activation. Annu Rev Immunol (1986) 5.67
ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain. Cell (1992) 5.53
The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes. J Immunol (1986) 5.27
Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line. J Exp Med (1984) 5.26
Regulation of interleukin-2 gene enhancer activity by the T cell accessory molecule CD28. Science (1991) 5.12
Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor. Cell (1992) 5.08
Human diversity in killer cell inhibitory receptor genes. Immunity (1997) 4.82
Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium. Proc Natl Acad Sci U S A (1984) 4.66
An activating immunoreceptor complex formed by NKG2D and DAP10. Science (1999) 4.56
In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers. J Exp Med (2000) 4.37
Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases. Science (1994) 4.23
Natural killer cells, viruses and cancer. Nat Rev Immunol (2001) 4.21
Induction of NF-kappaB by the Akt/PKB kinase. Curr Biol (1999) 4.03
Dissection of the lymphokine-activated killer phenomenon. Relative contribution of peripheral blood natural killer cells and T lymphocytes to cytolysis. J Exp Med (1986) 3.99
Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice. Immunity (2000) 3.84
Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors. Immunity (1997) 3.84
Human lymphocytes bearing T cell receptor gamma/delta are phenotypically diverse and evenly distributed throughout the lymphoid system. J Exp Med (1989) 3.70
CD28- T lymphocytes. Antigenic and functional properties. J Immunol (1993) 3.67
Characterization of two adhesins of Bordetella pertussis for human ciliated respiratory-epithelial cells. J Infect Dis (1985) 3.66
B70 antigen is a second ligand for CTLA-4 and CD28. Nature (1993) 3.57
The Bw4 public epitope of HLA-B molecules confers reactivity with natural killer cell clones that express NKB1, a putative HLA receptor. J Exp Med (1995) 3.43
Applications of retrovirus-mediated expression cloning. Exp Hematol (1996) 3.40
Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts. Nat Genet (2000) 3.39
LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway. Immunity (1998) 3.36
Monoclonal antibodies against rat immunoglobulin kappa chains. Hybridoma (1982) 3.36
The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction. Annu Rev Immunol (1994) 3.35
Comparative studies of human FcRIII-positive and negative natural killer cells. J Immunol (1989) 3.28
Ectopic expression of retinoic acid early inducible-1 gene (RAE-1) permits natural killer cell-mediated rejection of a MHC class I-bearing tumor in vivo. Proc Natl Acad Sci U S A (2001) 3.21
Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs. Nature (1992) 3.02
Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell. Science (1998) 2.93
The trans-neptunian object UB313 is larger than Pluto. Nature (2006) 2.88
Signal transduction by the TCR for antigen. Curr Opin Immunol (2000) 2.87
Urinary leukocyte esterase screening test for asymptomatic chlamydial and gonococcal infections in males. JAMA (1989) 2.87
Reconstitution of an active surface T3/T-cell antigen receptor by DNA transfer. Nature (1985) 2.84
DAP12-deficient mice fail to develop autoimmunity due to impaired antigen priming. Immunity (2000) 2.75
The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein. Proc Natl Acad Sci U S A (1991) 2.74
Expression of T3 in association with a molecule distinct from the T-cell antigen receptor heterodimer. Proc Natl Acad Sci U S A (1986) 2.73
ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency. Science (1994) 2.71
Antigen cap formation in cultured fibroblasts: a reflection of membrane fluidity and of cell motility. Proc Natl Acad Sci U S A (1972) 2.71
CD28 interaction with B7 costimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting T lymphocytes. J Exp Med (1992) 2.70
Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase. Science (1994) 2.70
The Fc receptor for IgG on human natural killer cells: phenotypic, functional, and comparative studies with monoclonal antibodies. J Immunol (1984) 2.70
The Ets-1 transcription factor is required for the development of natural killer cells in mice. Immunity (1998) 2.68
Fc alpha/mu receptor mediates endocytosis of IgM-coated microbes. Nat Immunol (2000) 2.66
Molecular cloning of NKB1. A natural killer cell receptor for HLA-B allotypes. J Immunol (1995) 2.63
NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules. J Exp Med (1994) 2.59
PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression. J Biol Chem (2000) 2.57
DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes. Immunity (1996) 2.56
Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines. Nat Immunol (2001) 2.55
The T cell antigen receptor complex expressed on normal peripheral blood CD4-, CD8- T lymphocytes. A CD3-associated disulfide-linked gamma chain heterodimer. J Exp Med (1987) 2.52
Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway. Nature (1990) 2.51
Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase. J Exp Med (1994) 2.47
Natural killer cells: definition of a cell type rather than a function. J Immunol (1986) 2.46
Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production. Proc Natl Acad Sci U S A (1991) 2.45
Superantigen-dependent, cell-mediated cytotoxicity inhibited by MHC class I receptors on T lymphocytes. Science (1995) 2.44
Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family. Immunogenetics (2001) 2.43
Activation of a human T cell line: a two-stimulus requirement in the pretranslational events involved in the coordinate expression of interleukin 2 and gamma-interferon genes. J Immunol (1985) 2.39
Expression and function of the CD3-antigen receptor on murine CD4+8+ thymocytes. Nature (1987) 2.38
A 275 basepair fragment at the 5' end of the interleukin 2 gene enhances expression from a heterologous promoter in response to signals from the T cell antigen receptor. J Exp Med (1987) 2.37
Distinct subsets of CD1d-restricted T cells recognize self-antigens loaded in different cellular compartments. J Exp Med (1999) 2.23
The immunological synapse and CD28-CD80 interactions. Nat Immunol (2001) 2.23
Recombinant interleukin 2 enhanced natural killer cell-mediated cytotoxicity in human lymphocyte subpopulations expressing the Leu 7 and Leu 11 antigens. J Immunol (1985) 2.20
Presence of Ti (WT31) negative T lymphocytes in normal blood and thymus. Nature (1987) 2.20
Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation. Immunity (1996) 2.18
Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain. J Exp Med (1993) 2.17
Structure, function, and serology of the T-cell antigen receptor complex. Annu Rev Immunol (1987) 2.17
Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site. Proc Natl Acad Sci U S A (1998) 2.16
p150/95, Third member of the LFA-1/CR3 polypeptide family identified by anti-Leu M5 monoclonal antibody. Eur J Immunol (1985) 2.14
B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells. J Exp Med (1994) 2.14
The antigen receptor on a human T cell line initiates activation by increasing cytoplasmic free calcium. J Immunol (1985) 2.13
Human natural killer cell receptors involved in MHC class I recognition are disulfide-linked heterodimers of CD94 and NKG2 subunits. J Immunol (1996) 2.13
Specific antigen-Ia activation of transfected human T cells expressing murine Ti alpha beta-human T3 receptor complexes. Nature (1987) 2.11
Cutting edge: the mouse NK cell-associated antigen recognized by DX5 monoclonal antibody is CD49b (alpha 2 integrin, very late antigen-2). J Immunol (2001) 2.09
Ly-49D and Ly-49H associate with mouse DAP12 and form activating receptors. J Immunol (1998) 2.06
Human natural killer cells isolated from peripheral blood do not rearrange T cell antigen receptor beta chain genes. J Exp Med (1986) 2.01
An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity. Cell (2000) 2.00
Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes. J Exp Med (1996) 1.98
Functional expression of B7/BB1 on activated T lymphocytes. J Exp Med (1993) 1.98
Activation of natural killer cells via the p75 interleukin 2 receptor. J Exp Med (1989) 1.95
T cell activation: differences in the signals required for IL 2 production by nonactivated and activated T cells. J Immunol (1985) 1.94
Specificity of HLA class I antigen recognition by human NK clones: evidence for clonal heterogeneity, protection by self and non-self alleles, and influence of the target cell type. J Exp Med (1993) 1.93
T cell antigen receptor signal transduction. Curr Opin Cell Biol (1997) 1.92
Rapid evolution of NK cell receptor systems demonstrated by comparison of chimpanzees and humans. Immunity (2000) 1.92
A model system for activation-induced alternative splicing of CD45 pre-mRNA in T cells implicates protein kinase C and Ras. Mol Cell Biol (2000) 1.90
Recovery of Bordetella pertussis from four kinds of swabs. Eur J Clin Microbiol (1987) 1.89
Ligands for natural killer cell receptors: redundancy or specificity. Immunol Rev (2001) 1.88
A functional T-cell receptor signaling pathway is required for p95vav activity. Mol Cell Biol (1995) 1.88
ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR zeta in murine thymocytes and lymph node T cells. Immunity (1994) 1.88
Relative contribution of the leukocyte molecules Mo1, LFA-1, and p150,95 (LeuM5) in adhesion of granulocytes and monocytes to vascular endothelium is tissue- and stimulus-specific. J Cell Physiol (1988) 1.88