Published in Curr Biol on February 16, 2000
The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation. EMBO J (2001) 3.80
The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases. Nucleic Acids Res (2004) 3.30
Counterregulation of chromatin deacetylation and histone deacetylase occupancy at the integrated promoter of human immunodeficiency virus type 1 (HIV-1) by the HIV-1 repressor YY1 and HIV-1 activator Tat. Mol Cell Biol (2002) 2.52
Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency. PLoS Biol (2011) 2.49
SIRT1 regulates HIV transcription via Tat deacetylation. PLoS Biol (2005) 2.24
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Methylation of Tat by PRMT6 regulates human immunodeficiency virus type 1 gene expression. J Virol (2005) 2.02
CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNA. Mol Cell Biol (2000) 1.89
BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism. Cell Cycle (2012) 1.88
Requirement for SWI/SNF chromatin-remodeling complex in Tat-mediated activation of the HIV-1 promoter. EMBO J (2006) 1.87
The Cellular lysine methyltransferase Set7/9-KMT7 binds HIV-1 TAR RNA, monomethylates the viral transactivator Tat, and enhances HIV transcription. Cell Host Microbe (2010) 1.76
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The Gln-Ala repeat transcriptional activator CA150 interacts with huntingtin: neuropathologic and genetic evidence for a role in Huntington's disease pathogenesis. Proc Natl Acad Sci U S A (2001) 1.51
Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain. EMBO J (2002) 1.49
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Effect of SWI/SNF chromatin remodeling complex on HIV-1 Tat activated transcription. Retrovirology (2006) 1.36
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A small molecule binding to the coactivator CREB-binding protein blocks apoptosis in cardiomyocytes. Chem Biol (2011) 1.35
Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1). PLoS Pathog (2011) 1.31
Arginine methylation of the human immunodeficiency virus type 1 Tat protein by PRMT6 negatively affects Tat Interactions with both cyclin T1 and the Tat transactivation region. J Virol (2007) 1.31
Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR. Retrovirology (2008) 1.30
AMF-1/Gps2 binds p300 and enhances its interaction with papillomavirus E2 proteins. J Virol (2000) 1.30
Differential acetylation of Tat coordinates its interaction with the co-activators cyclin T1 and PCAF. EMBO J (2002) 1.27
P/CAF-mediated acetylation regulates the function of the basic helix-loop-helix transcription factor TAL1/SCL. EMBO J (2000) 1.25
Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription. Retrovirology (2006) 1.25
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Gag induces the coalescence of clustered lipid rafts and tetraspanin-enriched microdomains at HIV-1 assembly sites on the plasma membrane. J Virol (2011) 1.18
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Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription. Retrovirology (2005) 1.13
In vitro nuclear interactome of the HIV-1 Tat protein. Retrovirology (2009) 1.13
A real-time view of the TAR:Tat:P-TEFb complex at HIV-1 transcription sites. Retrovirology (2007) 1.10
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Acetylated Tat regulates human immunodeficiency virus type 1 splicing through its interaction with the splicing regulator p32. J Virol (2006) 1.06
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Expression of a protein phosphatase 1 inhibitor, cdNIPP1, increases CDK9 threonine 186 phosphorylation and inhibits HIV-1 transcription. J Biol Chem (2010) 1.02
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Chromatin dynamics associated with HIV-1 Tat-activated transcription. Biochim Biophys Acta (2009) 1.01
Tat-induced FOXO3a is a key mediator of apoptosis in HIV-1-infected human CD4+ T lymphocytes. J Immunol (2008) 1.00
Association of Tat with promoters of PTEN and PP2A subunits is key to transcriptional activation of apoptotic pathways in HIV-infected CD4+ T cells. PLoS Pathog (2010) 0.99
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HIV-1 Tat interacts with LIS1 protein. Retrovirology (2005) 0.92
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The effect of N-acetylation and N-methylation of lysine residue of Tat peptide on its interaction with HIV-1 TAR RNA. PLoS One (2013) 0.78
The effects of cocaine on HIV transcription. J Neurovirol (2015) 0.78
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ZASC1 stimulates HIV-1 transcription elongation by recruiting P-TEFb and TAT to the LTR promoter. PLoS Pathog (2013) 0.76
The HIV-1 Tat Protein Is Monomethylated at Lysine 71 by the Lysine Methyltransferase KMT7. J Biol Chem (2016) 0.76
Modulation of the stability and activities of HIV-1 Tat by its ubiquitination and carboxyl-terminal region. Cell Biosci (2014) 0.76
Overexpression of PRMT6 does not suppress HIV-1 Tat transactivation in cells naturally lacking PRMT6. Virol J (2013) 0.76
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Combinations of isoform-targeted histone deacetylase inhibitors and bryostatin analogues display remarkable potency to activate latent HIV without global T-cell activation. Sci Rep (2017) 0.75
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