PubRank

G Merlino

Author PubWeight™ 84.61‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands. Genes Dev 1992 2.59
2 Neonatal sunburn and melanoma in mice. Nature 2001 2.25
3 Establishment and characterization of differentiated, nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor alpha. Proc Natl Acad Sci U S A 1994 2.20
4 Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor. Proc Natl Acad Sci U S A 1997 2.12
5 Transgenic mouse model for synergistic effects of nuclear oncogenes and growth factors in tumorigenesis: interaction of c-myc and transforming growth factor alpha in hepatic oncogenesis. Cancer Res 1993 2.09
6 Expression of a dominant-negative mutant TGF-beta type II receptor in transgenic mice reveals essential roles for TGF-beta in regulation of growth and differentiation in the exocrine pancreas. EMBO J 1997 2.08
7 Soluble dominant-negative receptor uncovers essential roles for fibroblast growth factors in multi-organ induction and patterning. EMBO J 1998 2.07
8 Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis. Cancer Res 1996 1.90
9 Targeting expression of a transforming growth factor beta 1 transgene to the pregnant mammary gland inhibits alveolar development and lactation. EMBO J 1993 1.86
10 Analysis of genetic instability during mammary tumor progression using a novel selection-based assay for in vivo mutations in a bacteriophage lambda transgene target. Proc Natl Acad Sci U S A 1996 1.73
11 Malignant melanoma: modern black plague and genetic black box. Genes Dev 1998 1.67
12 Renal cysts in transgenic mice expressing transforming growth factor-alpha. J Lab Clin Med 1994 1.66
13 Constitutive expression of a truncated INT3 gene in mouse mammary epithelium impairs differentiation and functional development. Cell Growth Differ 1995 1.62
14 Ectopic TGF beta 1 expression in the secretory mammary epithelium induces early senescence of the epithelial stem cell population. Dev Biol 1995 1.56
15 DNA-PKcs: a T-cell tumour suppressor encoded at the mouse scid locus. Nat Genet 1997 1.55
16 c-Met autocrine activation induces development of malignant melanoma and acquisition of the metastatic phenotype. Cancer Res 1998 1.54
17 Left ventricular diastolic and systolic function in normotensive obese subjects: influence of degree and duration of obesity. Eur Heart J 1992 1.52
18 Identification of VEGF-regulated genes associated with increased lung metastatic potential: functional involvement of tenascin-C in tumor growth and lung metastasis. Oncogene 2008 1.48
19 Cytological changes in the pancreas of transgenic mice overexpressing transforming growth factor alpha. Gastroenterology 1992 1.36
20 Hepatocyte growth factor/scatter factor overexpression induces growth, abnormal development, and tumor formation in transgenic mouse livers. Cell Growth Differ 1996 1.36
21 Scatter factor/hepatocyte growth factor as a regulator of skeletal muscle and neural crest development. Proc Natl Acad Sci U S A 1996 1.27
22 Involvement of hepatocyte growth factor/scatter factor and met receptor signaling in hair follicle morphogenesis and cycling. FASEB J 2000 1.26
23 Hypertrophic gastropathy resembling Ménétrier's disease in transgenic mice overexpressing transforming growth factor alpha in the stomach. J Clin Invest 1992 1.20
24 Transforming growth factor alpha disrupts the normal program of cellular differentiation in the gastric mucosa of transgenic mice. Development 1995 1.14
25 Dissection of RAS downstream pathways in melanomagenesis: a role for Ral in transformation. Oncogene 2010 1.13
26 Overexpression of transforming growth factor-alpha causes liver enlargement and increased hepatocyte proliferation in transgenic mice. Am J Pathol 1994 1.13
27 Exocrine pancreatic disorders in transsgenic mice expressing human keratin 8. J Clin Invest 1999 1.11
28 Autonomous growth in serum-free medium and production of hepatocellular carcinomas by differentiated hepatocyte lines that overexpress transforming growth factor alpha 1. Cancer Res 1994 1.11
29 Development of liver tumors in transforming growth factor alpha transgenic mice. Cancer Res 1992 1.10
30 Synergistic interaction of transforming growth factor alpha and c-myc in mouse mammary and salivary gland tumorigenesis. Cell Growth Differ 1995 1.10
31 Molecular and genetic analysis of liver oncogenesis in transforming growth factor alpha transgenic mice. Cancer Res 1992 1.05
32 Accelerated ultraviolet radiation-induced carcinogenesis in hepatocyte growth factor/scatter factor transgenic mice. Cancer Res 2000 0.99
33 Hepatocyte growth factor/scatter factor-MET signaling in neural crest-derived melanocyte development. Pigment Cell Res 1999 0.98
34 Disassociation of met-mediated biological responses in vivo: the natural hepatocyte growth factor/scatter factor splice variant NK2 antagonizes growth but facilitates metastasis. Mol Cell Biol 2000 0.98
35 Regulation of terminal differentiation of zymogenic cells by transforming growth factor alpha in transgenic mice. Gastroenterology 1995 0.97
36 Overexpression of hepatocyte growth factor/scatter factor promotes vascularization and granulation tissue formation in vivo. FEBS Lett 2001 0.96
37 Central obesity and hypertension. Relationship between fasting serum insulin, plasma renin activity, and diastolic blood pressure in young obese subjects. Am J Hypertens 1994 0.95
38 Transforming growth factor-alpha promotes mammary tumorigenesis through selective survival and growth of secretory epithelial cells. Am J Pathol 1995 0.95
39 NK1, a natural splice variant of hepatocyte growth factor/scatter factor, is a partial agonist in vivo. Mol Cell Biol 1998 0.93
40 The genetics of pancreatic adenocarcinoma: a roadmap for a mouse model. Semin Cancer Biol 2001 0.93
41 Renal tubular hyperplasia, polycystic disease, and glomerulosclerosis in transgenic mice overexpressing hepatocyte growth factor/scatter factor. Lab Invest 1997 0.92
42 Collaboration between growth factors and diverse chemical carcinogens in hepatocarcinogenesis of transforming growth factor alpha transgenic mice. Cancer Res 1993 0.91
43 Melanoma from bench to bedside: meeting report from the 6th international melanoma congress. Pigment Cell Melanoma Res 2009 0.89
44 Synergy between transforming growth factor alpha and hepatitis B virus surface antigen in hepatocellular proliferation and carcinogenesis. Cancer Res 1997 0.88
45 Changes in hemodynamics during isoflurane and propofol anesthesia: a comparison study. Neurol Res 2005 0.88
46 Central obesity and hypertension: pathophysiologic role of renal haemodynamics and function. Int J Obes Relat Metab Disord 1995 0.87
47 Increased susceptibility to N-nitrosomethylurea gastric carcinogenesis in transforming growth factor alpha transgenic mice with gastric hyperplasia. Jpn J Cancer Res 1995 0.86
48 Enhanced sensitivity to tumor growth and development in multistage skin carcinogenesis by transforming growth factor-alpha-induced epidermal growth factor receptor activation but not p53 inactivation. Mol Carcinog 1997 0.86
49 Heredity and obesity-associated hypertension: impact of hormonal characteristics and left ventricular mass. J Hypertens 1995 0.85
50 Ulcerative proctitis, rectal prolapse, and intestinal pseudo-obstruction in transgenic mice overexpressing hepatocyte growth factor/scatter factor. Lab Invest 2001 0.83
51 The p53 response to DNA damage in vivo is independent of DNA-dependent protein kinase. Mol Cell Biol 2000 0.83
52 Effect of obesity on left ventricular function studied by radionuclide angiocardiography. Int J Obes 1991 0.83
53 Transgenic mice provide genetic evidence that transforming growth factor alpha promotes skin tumorigenesis via H-ras-dependent and H-ras-independent pathways. Cell Growth Differ 1994 0.82
54 Overexpression of a human transforming growth factor-alpha (TGF alpha) transgene reveals a dual antagonistic role of TGF alpha in female sexual development. Endocrinology 1994 0.82
55 Transgenic mouse models of breast cancer. Breast Cancer Res Treat 1996 0.82
56 Genetic dissection of melanoma pathways in the mouse. Semin Cancer Biol 2001 0.82
57 [Sarcoidosis and clear cell carcinoma of the kidney: the sixth case?]. G Chir 2002 0.81
58 Drugs with anticholinergic properties as a risk factor for psychosis in patients affected by Alzheimer's disease. Clin Pharmacol Ther 2007 0.80
59 Immunohistochemical detection of the c-met proto-oncogene product in the congenital melanocytic nevus of an infant with neurocutaneous melanosis. J Am Acad Dermatol 2001 0.80
60 Histochemical analysis of hyperplastic stomach of TGF-alpha transgenic mice. Dig Dis Sci 1997 0.79
61 Heterotopic pregnancy following administration of human menopausal gonadotropin and following in vitro fertilization and embryo transfer: two case reports and review of the literature. Eur J Obstet Gynecol Reprod Biol 1995 0.79
62 Epidural anesthesia in an in vitro fertilization and embryo transfer program. J Assist Reprod Genet 1995 0.78
63 Hepatocarcinogenesis in transgenic mice. Prog Clin Biol Res 1995 0.78
64 Left ventricular function response to exercise in normotensive obese subjects: influence of degree and duration of obesity. Int J Cardiol 1992 0.78
65 Effects of amlodipine on renal haemodynamics in mild to moderate hypertensive patients. A randomized controlled study versus placebo. Eur J Clin Pharmacol 1993 0.77
66 Double-blind controlled study of rilmenidine versus hydrochlorothiazide in mild hypertension: clinical and renal haemodynamic evaluation. J Hum Hypertens 1993 0.77
67 New options for aerodigestive tract replacement after extended pharyngolaryngectomy. Laryngoscope 2000 0.77
68 General practitioners and mammographic screening uptake: influence of different modalities of general practitioner participation. Working Group. Tumori 2000 0.76
69 Steroid hormone-dependent overexpression of cytochromes P450 2A in liver tumors of TGF alpha transgenic male mice. J Gastroenterol 1997 0.76
70 Mechanisms of DES carcinogenicity: effects of the TGF alpha transgene. Prog Clin Biol Res 1997 0.76
71 Non-REM hypnic headache: a circadian disorder? A clinical and polysomnographic study. Cephalalgia 2007 0.76
72 [Gastric leiomyoma. Diagnostic and surgical problems]. G Chir 1999 0.76
73 An epidermal growth factor receptor promoter construct selectively expresses in the thymus and spleen of transgenic mice. Cell Immunol 1993 0.76
74 Reconstruction of the pharynx and cervical esophagus using ileocolic free autograft. Am J Surg 1999 0.75
75 [Current role of traditional endoscopy and prospects for virtual colonoscopy in the management of colorectal neoplastic lesions]. G Chir 2002 0.75
76 Interactions of TCDD with signal transduction and neoplastic development in c-myc transgenic and TGF-alpha transgenic mice. Arch Toxicol Suppl 1997 0.75
77 [Times of appearance of the arterial plethysmographic wave and the ultrasonogram in the study of arteriopathies]. Minerva Cardioangiol 1981 0.75
78 [Mechanism of action of estradiol valerate. II. Changes in the genital tract of rats castrated and subjected to prolonged treatment]. Arch Ostet Ginecol 1978 0.75
79 [Pentothal anesthesia and acid-base equilibrium in labor]. Arch Ostet Ginecol 1979 0.75
80 Histogenesis of anaplastic carcinomas of the thyroid, giant cell variety: immunocytochemical investigation. Appl Pathol 1985 0.75
81 Reduction of EGF receptor synthesis by antisense RNA vectors. FEBS Lett 1986 0.75
82 [Diagnosis and therapy of female sterility secondary to cervical and endometrial inflammation]. Arch Ostet Ginecol 1981 0.75
83 [Non-parasitic splenic cysts]. G Chir 2001 0.75
84 [Treatment with immunodepressant drugs in neonatal hemolytic disease caused by Rh isoimmunization (preliminary note)]. Arch Ostet Ginecol 1982 0.75
85 [Hereditary nonpolyposis colorectal cancer (Lynch syndrome): a review of the literature and case reports]. G Chir 2000 0.75
86 [Reconstructive strategies in head and neck cancer: case history review from 1992 to 1997 (154 cases)]. Acta Otorhinolaryngol Ital 1998 0.75
87 Potentiation of diethylstilbestrol-induced alterations in the female mouse reproductive tract by transforming growth factor-alpha transgene expression. Mol Carcinog 1996 0.75
88 [Diagnostic problems and therapeutic prospects in hirsutism]. Arch Ostet Ginecol 1980 0.75
89 [A method of localization of incompetant perforating veins by means of rheoscopy with ultrasonics]. Ann Ital Chir 1979 0.75
90 [Management of delivery in patients with previous cesarean sections (preliminary note)]. Arch Ostet Ginecol 1982 0.75
91 [Functional exploration of fetal acid-base equilibrium in directed labor under propanidid anesthesia]. Arch Ostet Ginecol 1979 0.75
92 [Doppler ultrasonography in phlebology]. Minerva Cardioangiol 1982 0.75
93 A 38 kg skin-reducing bilateral mastectomy: a unique case. J Plast Reconstr Aesthet Surg 2008 0.75
94 Evidence that reduction of hepatocyte growth factor (HGF) is not required for peroxisome proliferator-induced hepatocyte proliferation. Carcinogenesis 2001 0.75
95 Obesity, hypertension and atherosclerosis. Int Angiol 1993 0.75
96 [Current role of endoscopic ultrasonography in the treatment of colorectal neoplastic lesions]. G Chir 2002 0.75
97 [Gamma-OH anesthesia and acid-base equilibrium in labor]. Arch Ostet Ginecol 1979 0.75
98 [Ileocolic free autograft in advanced cervical oncology]. Acta Otorhinolaryngol Ital 1999 0.75
99 [Treatment with immunodepressors in cases of hemolytic diseases of the newborn caused by materno-fetal Rh isoimmunization]. Arch Ostet Ginecol 1982 0.75
100 [Etiopathogenetic and therapeutic problems of superficial thrombophlebitis during antiblastic therapy]. Ann Ital Chir 1981 0.75