Published in Genes Dev on March 01, 1992
Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. J Exp Med (1996) 4.79
Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2. Mol Cell Biol (1996) 4.26
Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation. EMBO J (1999) 3.95
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Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells. Cancer Cell (2011) 3.32
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Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium. Proc Natl Acad Sci U S A (2001) 2.56
SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function. Mol Cell Biol (2000) 2.27
Conservation of the Drosophila lateral inhibition pathway in human lung cancer: a hairy-related protein (HES-1) directly represses achaete-scute homolog-1 expression. Proc Natl Acad Sci U S A (1997) 2.00
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Use of three-dimensional basement membrane cultures to model oncogene-induced changes in mammary epithelial morphogenesis. J Mammary Gland Biol Neoplasia (2004) 1.71
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Notch signalling in cancer progression and bone metastasis. Br J Cancer (2011) 1.09
Significance of glycosylation in Notch signaling. Biochem Biophys Res Commun (2014) 1.09
Notch activation stimulates migration of breast cancer cells and promotes tumor growth. Breast Cancer Res (2013) 1.08
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NOTCH1 inhibition in vivo results in mammary tumor regression and reduced mammary tumorsphere-forming activity in vitro. Breast Cancer Res (2012) 1.02
Identification of novel targets of CSL-dependent Notch signaling in hematopoiesis. PLoS One (2011) 1.02
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Overexpression of human Cripto-1 in transgenic mice delays mammary gland development and differentiation and induces mammary tumorigenesis. Am J Pathol (2005) 0.99
The intracellular form of notch blocks transforming growth factor beta-mediated growth arrest in Mv1Lu epithelial cells. Mol Cell Biol (2003) 0.99
Notch and the awesome power of genetics. Genetics (2012) 0.99
Notch3 functions as a tumor suppressor by controlling cellular senescence. Cancer Res (2013) 0.98
Intracellular activated Notch1 is critical for proliferation of Kaposi's sarcoma-associated herpesvirus-associated B-lymphoma cell lines in vitro. J Virol (2006) 0.98
Notch1 signaling regulates the epithelial-mesenchymal transition and invasion of breast cancer in a Slug-dependent manner. Mol Cancer (2015) 0.98
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Kaposi's sarcoma herpesvirus-encoded latency-associated nuclear antigen stabilizes intracellular activated Notch by targeting the Sel10 protein. Proc Natl Acad Sci U S A (2007) 0.93
ΔNp63α promotes cellular quiescence via induction and activation of Notch3. Cell Cycle (2011) 0.92
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Crosstalk between PKCα and Notch-4 in endocrine-resistant breast cancer cells. Oncogenesis (2013) 0.91
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Expression of Notch receptors, ligands, and target genes during development of the mouse mammary gland. J Cell Physiol (2011) 0.90
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Notch-induced mammary tumorigenesis does not involve the lobule-limited epithelial progenitor. Oncogene (2011) 0.89
Intracisternal type A particle-mediated activation of the Notch4/int3 gene in a mouse mammary tumor: generation of truncated Notch4/int3 mRNAs by retroviral splicing events. J Virol (1999) 0.87
Trp53 regulates Notch 4 signaling through Mdm2. J Cell Sci (2011) 0.84
Peroxisome-proliferator-activated receptor-binding protein (PBP) is essential for the growth of active Notch4-immortalized mammary epithelial cells by activating SOX10 expression. Biochem J (2009) 0.84
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Glucocorticoid and growth factor synergism requirement for Notch4 chromatin domain activation. Mol Cell Biol (2007) 0.83
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Anti-DLL4, a cancer therapeutic with multiple mechanisms of action. Vasc Cell (2011) 0.82
Developmental signaling pathways regulating mammary stem cells and contributing to the etiology of triple-negative breast cancer. Breast Cancer Res Treat (2016) 0.80
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Sequences within the gag gene of mouse mammary tumor virus needed for mammary gland cell transformation. J Virol (2006) 0.79
Molecular cues for development and regeneration of salivary glands. Histol Histopathol (2013) 0.79
AKT and 14-3-3 regulate Notch4 nuclear localization. Sci Rep (2015) 0.79
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'Normalizing' the malignant phenotype of luminal breast cancer cells via alpha(v)beta(3)-integrin. Cell Death Dis (2016) 0.75
Original Research: Featured Article: Imatinib mesylate (Gleevec) inhibits Notch and c-Myc signaling: Five-day treatment permanently rescues mammary development. Exp Biol Med (Maywood) (2016) 0.75
Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer. Oncotarget (2017) 0.75
Targeting the Notch signaling pathway in cancer therapeutics. Thorac Cancer (2014) 0.75
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