Published in Cancer Med on January 12, 2014
Galectin-3 in angiogenesis and metastasis. Glycobiology (2014) 0.97
Extracellular galectin-3 in tumor progression and metastasis. Front Oncol (2014) 0.97
Galectin-3 up-regulation in hypoxic and nutrient deprived microenvironments promotes cell survival. PLoS One (2014) 0.82
Identification of polarized macrophage subsets in zebrafish. Elife (2015) 0.80
Galectin-3 Determines Tumor Cell Adaptive Strategies in Stressed Tumor Microenvironments. Front Oncol (2016) 0.77
Dysregulation of TGFβ1 Activity in Cancer and Its Influence on the Quality of Anti-Tumor Immunity. J Clin Med (2016) 0.77
Galectin-3 as a Potential Target to Prevent Cancer Metastasis. Clin Med Insights Oncol (2015) 0.77
The deficiency of galectin-3 in stromal cells leads to enhanced tumor growth and bone marrow metastasis. BMC Cancer (2016) 0.77
Glycobiology of ocular angiogenesis. Glycobiology (2014) 0.76
Promising landscape for regulating macrophage polarization: epigenetic viewpoint. Oncotarget (2017) 0.75
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A (1979) 365.71
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol (2002) 82.19
A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J Med (2004) 41.02
TGF-beta signaling in tumor suppression and cancer progression. Nat Genet (2001) 11.64
Galectins as modulators of tumour progression. Nat Rev Cancer (2005) 5.30
Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation. J Leukoc Biol (2009) 4.53
Galectin-3 regulates myofibroblast activation and hepatic fibrosis. Proc Natl Acad Sci U S A (2006) 2.75
Sp1 binding is inhibited by (m)Cp(m)CpG methylation. Gene (1997) 2.50
Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses. Am J Pathol (2000) 2.40
Macrophages and tissue injury: agents of defense or destruction? Annu Rev Pharmacol Toxicol (2011) 2.28
Regulation of alternative macrophage activation by galectin-3. J Immunol (2008) 2.28
Transforming growth factor-beta in cutaneous melanoma. Pigment Cell Melanoma Res (2008) 2.03
Inhibition of endothelial cell proliferation by type beta-transforming growth factor: interactions with acidic and basic fibroblast growth factors. Biochem Biophys Res Commun (1986) 1.97
Galectin-3 induces endothelial cell morphogenesis and angiogenesis. Am J Pathol (2000) 1.97
Transforming growth factor-beta (TGF beta) is chemotactic for human monocytes and induces their expression of angiogenic activity. Biochem Biophys Res Commun (1988) 1.54
Tumor-infiltrating macrophages correlate with adverse prognosis and Epstein-Barr virus status in classical Hodgkin's lymphoma. Haematologica (2010) 1.54
Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response. J Exp Med (2010) 1.41
TGFβ signaling plays a critical role in promoting alternative macrophage activation. BMC Immunol (2012) 1.27
Galectin-3 cleavage: a novel surrogate marker for matrix metalloproteinase activity in growing breast cancers. Cancer Res (2007) 1.25
Galectin-3 contributes to neonatal hypoxic-ischemic brain injury. Neurobiol Dis (2010) 1.21
Shuttling of galectin-3 between the nucleus and cytoplasm. Glycobiology (2002) 1.16
Galectin-3 protein modulates cell surface expression and activation of vascular endothelial growth factor receptor 2 in human endothelial cells. J Biol Chem (2011) 1.13
Melanocyte transformation associated with substrate adhesion impediment. Neoplasia (2006) 1.06
Differential expression of galectins in normal, benign and malignant prostate epithelial cells: silencing of galectin-3 expression in prostate cancer by its promoter methylation. Biochem Biophys Res Commun (2007) 1.05
Epigenetic silencing of the adhesion molecule ADAM23 is highly frequent in breast tumors. Oncogene (2004) 1.02
Transient inflammatory response induced by apoptotic cells is an important mediator of melanoma cell engraftment and growth. Int J Cancer (2005) 1.01
Proteomic and SAGE profiling of murine melanoma progression indicates the reduction of proteins responsible for ROS degradation. Proteomics (2006) 1.00
Galectin-3 expression is associated with tumor progression and pattern of sun exposure in melanoma. Clin Cancer Res (2006) 1.00
High yield electroblotting onto polyvinylidene difluoride membranes from polyacrylamide gels. Electrophoresis (1992) 1.00
VEGFR1 and VEGFR2 involvement in extracellular galectin-1- and galectin-3-induced angiogenesis. PLoS One (2013) 0.99
Hypoxia-induced secretion of TGF-β1 in mesenchymal stem cell promotes breast cancer cell progression. Cell Transplant (2012) 0.99
Expression of PAFR as part of a prosurvival response to chemotherapy: a novel target for combination therapy in melanoma. Mediators Inflamm (2012) 0.97
Role of galectin-3 in classical and alternative macrophage activation in the liver following acetaminophen intoxication. J Immunol (2012) 0.96
The role of the tumor microenvironment in regulating angiogenesis. Cold Spring Harb Perspect Med (2012) 0.93
Evidence of heavy methylation in the galectin 3 promoter in early stages of prostate adenocarcinoma: development and validation of a methylated marker for early diagnosis of prostate cancer. Transl Oncol (2009) 0.92
Promoter Methylation in Prostate Cancer and its Application for the Early Detection of Prostate Cancer Using Serum and Urine Samples. Biomark Cancer (2010) 0.91
DAMGO-induced expression of chemokines and chemokine receptors: the role of TGF-beta1. J Leukoc Biol (2008) 0.89
Galectin-1 is silenced by promoter hypermethylation and its re-expression induces apoptosis in human colorectal cancer cells. Cancer Lett (2010) 0.88
Effects of DNA methylation on galectin-3 expression in pituitary tumors. Cancer Res (2005) 0.88
Galectin-3 accelerates M2 macrophage infiltration and angiogenesis in tumors. Am J Pathol (2013) 0.86
Epigenetic reprogramming as a key contributor to melanocyte malignant transformation. Epigenetics (2011) 0.86
Association of galectin-3 expression with melanoma progression and prognosis. Eur J Cancer (2011) 0.82
Lack of galectin-3 disturbs mesenteric lymph node homeostasis and B cell niches in the course of Schistosoma mansoni infection. PLoS One (2011) 0.81
Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer. Genome Res (2011) 3.36
Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosis. Am J Pathol (2008) 2.83
Galectins: structure, function and therapeutic potential. Expert Rev Mol Med (2008) 2.61
Prognostic implications of altered human epidermal growth factor receptors (HERs) in gastric carcinomas: HER2 and HER3 are predictors of poor outcome. J Clin Oncol (2011) 2.36
Critical role of galectin-3 in phagocytosis by macrophages. J Clin Invest (2003) 2.18
Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death. J Immunol (2006) 2.14
Evidence that IgE molecules mediate a spectrum of effects on mast cell survival and activation via aggregation of the FcepsilonRI. Proc Natl Acad Sci U S A (2003) 1.94
Galectin-3 induces death of Candida species expressing specific beta-1,2-linked mannans. J Immunol (2006) 1.61
Tumor-derived microvesicles modulate the establishment of metastatic melanoma in a phosphatidylserine-dependent manner. Cancer Lett (2009) 1.60
Galectins-3 and -7, but not galectin-1, play a role in re-epithelialization of wounds. J Biol Chem (2002) 1.58
Dynamics of neutrophil infiltration during cutaneous wound healing and infection using fluorescence imaging. J Invest Dermatol (2008) 1.42
Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response. J Exp Med (2010) 1.41
Sialylation of beta1 integrins blocks cell adhesion to galectin-3 and protects cells against galectin-3-induced apoptosis. J Biol Chem (2008) 1.40
Therapeutic effect of cytotoxic T lymphocyte antigen 4/immunoglobulin on a murine model of primary biliary cirrhosis. Hepatology (2013) 1.33
Galectin-3 is a negative regulator of lipopolysaccharide-mediated inflammation. J Immunol (2008) 1.29
Galectin-3 deficiency reduces the severity of experimental autoimmune encephalomyelitis. J Immunol (2009) 1.28
Galectin-3 promotes lamellipodia formation in epithelial cells by interacting with complex N-glycans on alpha3beta1 integrin. J Cell Sci (2009) 1.26
Cell mechanics using atomic force microscopy-based single-cell compression. Langmuir (2006) 1.26
Galectin-7 (PIG1) exhibits pro-apoptotic function through JNK activation and mitochondrial cytochrome c release. J Biol Chem (2001) 1.25
Galectin-3 mediates IL-4-induced survival and differentiation of B cells: functional cross-talk and implications during Trypanosoma cruzi infection. J Immunol (2004) 1.24
Role of galectin-3 in human pulmonary fibrosis. Allergol Int (2007) 1.24
Galectin-3 functions as an adhesion molecule to support eosinophil rolling and adhesion under conditions of flow. J Immunol (2007) 1.23
Critical role for galectin-3 in airway inflammation and bronchial hyperresponsiveness in a murine model of asthma. Am J Pathol (2004) 1.22
LacdiNAc-glycans constitute a parasite pattern for galectin-3-mediated immune recognition. J Immunol (2004) 1.22
Galectin 3 and its binding protein in rheumatoid arthritis. Arthritis Rheum (2003) 1.20
Regulation of cellular homeostasis by galectins. Glycoconj J (2004) 1.20
Prognostic value of NDRG1 and SPARC protein expression in breast cancer patients. Breast Cancer Res Treat (2010) 1.19
Pro-inflammatory secretory phospholipase A2 type IIA binds to integrins alphavbeta3 and alpha4beta1 and induces proliferation of monocytic cells in an integrin-dependent manner. J Biol Chem (2008) 1.16
Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse. Proc Natl Acad Sci U S A (2009) 1.16
Toxoplasma gondii infection reveals a novel regulatory role for galectin-3 in the interface of innate and adaptive immunity. Am J Pathol (2006) 1.14
Galectin-3 regulates T-cell functions. Immunol Rev (2009) 1.14
Endogenous galectin-3 is localized in membrane lipid rafts and regulates migration of dendritic cells. J Invest Dermatol (2008) 1.13
IgE-dependent mast cell activation potentiates airway responses in murine asthma models. J Immunol (2002) 1.13
Role of galectin-3 in mast cell functions: galectin-3-deficient mast cells exhibit impaired mediator release and defective JNK expression. J Immunol (2006) 1.12
The direct binding of insulin-like growth factor-1 (IGF-1) to integrin alphavbeta3 is involved in IGF-1 signaling. J Biol Chem (2009) 1.12
Galectins in apoptosis. Methods Enzymol (2006) 1.12
Concomitant expression of epithelial-mesenchymal transition biomarkers in breast ductal carcinoma: association with progression. Oncol Rep (2010) 1.11
The immunological potential of galectin-1 and -3. Autoimmun Rev (2008) 1.11
Galectin-3 preserves renal tubules and modulates extracellular matrix remodeling in progressive fibrosis. Am J Physiol Renal Physiol (2010) 1.10
Impaired retinal angiogenesis in diabetes: role of advanced glycation end products and galectin-3. Diabetes (2005) 1.08
Allergen-induced airway remodeling is impaired in galectin-3-deficient mice. J Immunol (2010) 1.07
Melanocyte transformation associated with substrate adhesion impediment. Neoplasia (2006) 1.06
Homodimeric galectin-7 (p53-induced gene 1) is a negative growth regulator for human neuroblastoma cells. Oncogene (2003) 1.05
Emerging technologies in extracellular vesicle-based molecular diagnostics. Expert Rev Mol Diagn (2014) 1.04
Galectin-3 is critical for the development of the allergic inflammatory response in a mouse model of atopic dermatitis. Am J Pathol (2009) 1.03
Mast cells and immunological skin diseases. Clin Rev Allergy Immunol (2007) 1.03
Suppression of tumor growth by galectin-7 gene transfer. Cancer Res (2004) 1.02
Transient inflammatory response induced by apoptotic cells is an important mediator of melanoma cell engraftment and growth. Int J Cancer (2005) 1.01
The ESCRT machinery is recruited by the viral BFRF1 protein to the nucleus-associated membrane for the maturation of Epstein-Barr Virus. PLoS Pathog (2012) 1.01
LPS-induced galectin-3 oligomerization results in enhancement of neutrophil activation. PLoS One (2011) 1.01
Proteomic and SAGE profiling of murine melanoma progression indicates the reduction of proteins responsible for ROS degradation. Proteomics (2006) 1.00
Platelet-activating factor receptor (PAF-R)-dependent pathways control tumour growth and tumour response to chemotherapy. BMC Cancer (2010) 1.00
Down-regulation of the candidate tumor suppressor gene PAR-4 is associated with poor prognosis in breast cancer. Int J Oncol (2010) 1.00
Arg72Pro TP53 polymorphism and cancer susceptibility: a comprehensive meta-analysis of 302 case-control studies. Int J Cancer (2010) 1.00
Evaluation of cell cycle protein expression in gastric cancer: cyclin B1 expression and its prognostic implication. Hum Pathol (2010) 0.99
The constitutive expression of galectin-3 is downregulated in the intestinal epithelia of Crohn's disease patients, and tumour necrosis factor alpha decreases the level of galectin-3-specific mRNA in HCT-8 cells. Eur J Gastroenterol Hepatol (2002) 0.99
Correlation of MGMT promoter methylation status with gene and protein expression levels in glioblastoma. Clinics (Sao Paulo) (2011) 0.99
Galectin-12 is required for adipogenic signaling and adipocyte differentiation. J Biol Chem (2004) 0.99
B cell depletion therapy exacerbates murine primary biliary cirrhosis. Hepatology (2010) 0.99
Altered expression of galectin-3 induces cortical thymocyte depletion and premature exit of immature thymocytes during Trypanosoma cruzi infection. Am J Pathol (2007) 0.99
The COOH-terminal globular domain of fibrinogen gamma chain suppresses angiogenesis and tumor growth. Cancer Res (2006) 0.98
Galectin-3 regulates intracellular trafficking of EGFR through Alix and promotes keratinocyte migration. J Invest Dermatol (2012) 0.98
ADAM23 negatively modulates alpha(v)beta(3) integrin activation during metastasis. Cancer Res (2009) 0.98
An anti-apoptotic role for galectin-3 in diffuse large B-cell lymphomas. Am J Pathol (2004) 0.98
Foxp3 expression is associated with aggressiveness in differentiated thyroid carcinomas. Clinics (Sao Paulo) (2012) 0.98
Proteomic analysis of low- to high-grade astrocytomas reveals an alteration of the expression level of raf kinase inhibitor protein and nucleophosmin. Proteomics (2010) 0.97
Expression of PAFR as part of a prosurvival response to chemotherapy: a novel target for combination therapy in melanoma. Mediators Inflamm (2012) 0.97
Association of a macrophage galactoside-binding protein with Mycobacterium-containing phagosomes. Cell Microbiol (2002) 0.97
Differentiated thyroid carcinomas may elude the immune system by B7H1 upregulation. Endocr Relat Cancer (2013) 0.96
Acromegaly: correlation between expression of somatostatin receptor subtypes and response to octreotide-lar treatment. Pituitary (2009) 0.96
Changes in galectin-7 and cytokeratin-19 expression during the progression of malignancy in thyroid tumors: diagnostic and biological implications. Mod Pathol (2002) 0.95
Identification of human exons overexpressed in tumors through the use of genome and expressed sequence data. Physiol Genomics (2005) 0.95
Galectin-3 negatively regulates dendritic cell production of IL-23/IL-17-axis cytokines in infection by Histoplasma capsulatum. J Immunol (2013) 0.95
Rosacea: skin innate immunity gone awry? Nat Med (2007) 0.95
Inhibition of advanced glycation and absence of galectin-3 prevent blood-retinal barrier dysfunction during short-term diabetes. Exp Diabetes Res (2007) 0.94
Galectin-3 modulates phagocytosis-induced stellate cell activation and liver fibrosis in vivo. Am J Physiol Gastrointest Liver Physiol (2011) 0.94
Infiltration of a mixture of immune cells may be related to good prognosis in patients with differentiated thyroid carcinoma. Clin Endocrinol (Oxf) (2012) 0.94
Immunocytochemical expression of p16INK4A and Ki-67 in cytologically negative and equivocal pap smears positive for oncogenic human papillomavirus. Int J Gynecol Pathol (2005) 0.94
Malignant transformation in melanocytes is associated with increased production of procoagulant microvesicles. Thromb Haemost (2011) 0.93
Nuclear localization of Galectin-3 in transformed thyroid cells: a role in transcriptional regulation. Biochem Biophys Res Commun (2003) 0.93
Involvement of protein tyrosine kinase in Toll-like receptor 4-mediated NF-kappa B activation in human peripheral blood monocytes. Am J Physiol Lung Cell Mol Physiol (2002) 0.93
Galectin-3 protects keratinocytes from UVB-induced apoptosis by enhancing AKT activation and suppressing ERK activation. J Invest Dermatol (2008) 0.93
IL-1 receptor-associated kinase and low molecular weight GTPase RhoA signal molecules are required for bacterial lipopolysaccharide-induced cytokine gene transcription. J Immunol (2002) 0.93
Higher bone marrow LGALS3 expression is an independent unfavorable prognostic factor for overall survival in patients with acute myeloid leukemia. Blood (2013) 0.92
Comparative transcriptomic analyses of atopic dermatitis and psoriasis reveal shared neutrophilic inflammation. J Allergy Clin Immunol (2012) 0.92
Lack of galectin-3 alters the balance of innate immune cytokines and confers resistance to Rhodococcus equi infection. Eur J Immunol (2008) 0.92
Galectin-3 stimulates preadipocyte proliferation and is up-regulated in growing adipose tissue. Obesity (Silver Spring) (2007) 0.92
Inhibition of angiotensin II receptor 1 limits tumor-associated angiogenesis and attenuates growth of murine melanoma. Cancer Chemother Pharmacol (2009) 0.91
XPC polymorphisms play a role in tissue-specific carcinogenesis: a meta-analysis. Eur J Hum Genet (2008) 0.91
Dissection of antigen-specific humoral and cellular immune responses for the development of experimental immune-mediated blepharoconjunctivitis in C57BL/6 mice. Curr Eye Res (2005) 0.91
European ancestry and polymorphisms in DNA repair genes modify the risk of melanoma: a case-control study in a high UV index region in Brazil. J Dermatol Sci (2011) 0.91
Galectin-3 binds to CD45 on diffuse large B-cell lymphoma cells to regulate susceptibility to cell death. Blood (2012) 0.91
Ablation of a galectin preferentially expressed in adipocytes increases lipolysis, reduces adiposity, and improves insulin sensitivity in mice. Proc Natl Acad Sci U S A (2011) 0.90
Leukotriene B4 creates a favorable microenvironment for murine melanoma growth. Mol Cancer Res (2009) 0.90