Published in Cancer Res on February 15, 2000
Regulation of cell invasion and morphogenesis in a three-dimensional type I collagen matrix by membrane-type matrix metalloproteinases 1, 2, and 3. J Cell Biol (2000) 3.53
Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion. EMBO J (2001) 2.23
Metzincin proteases and their inhibitors: foes or friends in nervous system physiology? J Neurosci (2010) 1.41
MT4-(MMP17) and MT6-MMP (MMP25), A unique set of membrane-anchored matrix metalloproteinases: properties and expression in cancer. Cancer Metastasis Rev (2008) 1.34
Matrix metalloproteinase control of capillary morphogenesis. Crit Rev Eukaryot Gene Expr (2008) 1.32
Neutrophil extracellular traps induce endothelial dysfunction in systemic lupus erythematosus through the activation of matrix metalloproteinase-2. Ann Rheum Dis (2014) 1.25
Characterization of matrix metalloproteinase-26, a novel metalloproteinase widely expressed in cancer cells of epithelial origin. Biochem J (2001) 1.16
Matrix metalloproteinase proteolysis of the myelin basic protein isoforms is a source of immunogenic peptides in autoimmune multiple sclerosis. PLoS One (2009) 1.11
Activation of pro-(matrix metalloproteinase-2) (pro-MMP-2) by thrombin is membrane-type-MMP-dependent in human umbilical vein endothelial cells and generates a distinct 63 kDa active species. Biochem J (2001) 1.08
New Strategies for the Next Generation of Matrix-Metalloproteinase Inhibitors: Selectively Targeting Membrane-Anchored MMPs with Therapeutic Antibodies. Biochem Res Int (2010) 1.07
Differential expression and localization of TIMP-1 and TIMP-4 in human gliomas. Br J Cancer (2001) 1.03
MMP25 (MT6-MMP) is highly expressed in human colon cancer, promotes tumor growth, and exhibits unique biochemical properties. J Biol Chem (2007) 1.01
Induction of membrane-type-1 matrix metalloproteinase by epidermal growth factor-mediated signaling in gliomas. Neuro Oncol (2004) 0.92
A complete compilation of matrix metalloproteinase expression in human malignant gliomas. World J Clin Oncol (2012) 0.89
Biochemical characterization of the cellular glycosylphosphatidylinositol-linked membrane type-6 matrix metalloproteinase. J Biol Chem (2010) 0.88
Myocardial remodeling in viral heart disease: possible interactions between inflammatory mediators and MMP-TIMP system. Heart Fail Rev (2004) 0.85
Heat shock-mediated transient increase in intracellular 3',5'-cyclic AMP results in tumor specific suppression of membrane type 1-matrix metalloproteinase production and progelatinase A activation. Clin Exp Metastasis (2000) 0.85
The structure and regulation of the human and mouse matrix metalloproteinase-21 gene and protein. Biochem J (2003) 0.85
Comparative expression pattern of Matrix-Metalloproteinases in human glioblastoma cell-lines and primary cultures. BMC Res Notes (2010) 0.83
Synthesis and biological evaluation in U87MG glioma cells of (ethynylthiophene)sulfonamido-based hydroxamates as matrix metalloproteinase inhibitors. Eur J Med Chem (2011) 0.82
Matrix metalloproteinase-25 has a functional role in mouse secondary palate development and is a downstream target of TGF-β3. BMC Dev Biol (2010) 0.81
Selecting Targets for Tumor Imaging: An Overview of Cancer-Associated Membrane Proteins. Biomark Cancer (2016) 0.77
Matrix metalloproteinases in the brain and blood-brain barrier: Versatile breakers and makers. J Cereb Blood Flow Metab (2016) 0.77
Ovarian membrane-type matrix metalloproteinases: induction of MMP14 and MMP16 during the periovulatory period in the rat, macaque, and human. Biol Reprod (2014) 0.76
Is collagenase-3 (MMP-13) expression in chondrosarcoma of the jaws a true marker for tumor aggressiveness? Diagn Pathol (2008) 0.75
Biochemical and Biological Attributes of Matrix Metalloproteinases. Prog Mol Biol Transl Sci (2017) 0.75
Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas. J Biol Chem (1994) 3.64
Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells. Cancer Res (2001) 3.62
PI3K inhibition results in enhanced HER signaling and acquired ERK dependency in HER2-overexpressing breast cancer. Oncogene (2011) 3.59
Molecular structure of a gene, VMA1, encoding the catalytic subunit of H(+)-translocating adenosine triphosphatase from vacuolar membranes of Saccharomyces cerevisiae. J Biol Chem (1990) 3.47
Persistence of muscle catabolism after severe burn. Surgery (2000) 3.34
Opening of mitochondrial K(ATP) channels triggers the preconditioned state by generating free radicals. Circ Res (2000) 3.19
Ara6, a plant-unique novel type Rab GTPase, functions in the endocytic pathway of Arabidopsis thaliana. EMBO J (2001) 3.17
Lapatinib, a HER2 tyrosine kinase inhibitor, induces stabilization and accumulation of HER2 and potentiates trastuzumab-dependent cell cytotoxicity. Oncogene (2008) 2.72
Branhamella catarrhalis respiratory infections. Rev Infect Dis (1988) 2.51
CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to gamma-secretase inhibitors. Leukemia (2006) 2.40
Extrapulmonary tuberculosis revisited: a review of experience at Boston City and other hospitals. Medicine (Baltimore) (1984) 2.28
Exogenous amino acids stimulate net muscle protein synthesis in the elderly. J Clin Invest (1998) 2.25
DNA profiling analysis of 100 consecutive de novo acute myeloid leukemia cases reveals patterns of genomic instability that affect all cytogenetic risk groups. Leukemia (2007) 2.20
Identification and enzymatic characterization of two diverging murine counterparts of human interstitial collagenase (MMP-1) expressed at sites of embryo implantation. J Biol Chem (2000) 2.12
Deubiquitinases in cancer: new functions and therapeutic options. Oncogene (2011) 2.08
Analysis of 16 different matrix metalloproteinases (MMP-1 to MMP-20) in the synovial membrane: different profiles in trauma and rheumatoid arthritis. Ann Rheum Dis (1999) 2.06
The content and accessibility of sex education information on the Internet. Health Educ Behav (2000) 2.04
Postexercise net protein synthesis in human muscle from orally administered amino acids. Am J Physiol (1999) 2.00
Dysgonic fermenter 2 septicemia. Rev Infect Dis (1988) 1.88
Collagenase 3 is a target of Cbfa1, a transcription factor of the runt gene family involved in bone formation. Mol Cell Biol (1999) 1.87
A novel gene, STT4, encodes a phosphatidylinositol 4-kinase in the PKC1 protein kinase pathway of Saccharomyces cerevisiae. J Biol Chem (1994) 1.87
A dominant negative mutant of sar1 GTPase inhibits protein transport from the endoplasmic reticulum to the Golgi apparatus in tobacco and Arabidopsis cultured cells. Plant J (2000) 1.84
Endoplasmic reticulum localization of Sec12p is achieved by two mechanisms: Rer1p-dependent retrieval that requires the transmembrane domain and Rer1p-independent retention that involves the cytoplasmic domain. J Cell Biol (1996) 1.82
The helping hand of collagenase-3 (MMP-13): 2.7 A crystal structure of its C-terminal haemopexin-like domain. J Mol Biol (1996) 1.82
Mechanism of action of trastuzumab and scientific update. Semin Oncol (2001) 1.77
Clinical and epidemiologic features of strongyloidiasis. A prospective study in rural Tennessee. Arch Intern Med (1987) 1.74
Structural analysis and promoter characterization of the human collagenase-3 gene (MMP13). Genomics (1997) 1.73
Antimicrobial resistance and spread of class 1 integrons among Salmonella serotypes. Antimicrob Agents Chemother (2000) 1.71
The plasma membrane of Saccharomyces cerevisiae: structure, function, and biogenesis. Microbiol Rev (1995) 1.69
Resistance training reduces the acute exercise-induced increase in muscle protein turnover. Am J Physiol (1999) 1.68
Rer1p, a retrieval receptor for endoplasmic reticulum membrane proteins, is dynamically localized to the Golgi apparatus by coatomer. J Cell Biol (2001) 1.67
Clinical comparison of the isolator and BacT/Alert aerobic blood culture systems. J Clin Microbiol (1995) 1.67
Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity. J Biol Chem (1999) 1.67
Anabolic effects of oxandrolone after severe burn. Ann Surg (2001) 1.65
Structural and functional dissection of a membrane glycoprotein required for vesicle budding from the endoplasmic reticulum. Mol Cell Biol (1991) 1.62
Cleavage of the HER2 ectodomain is a pervanadate-activable process that is inhibited by the tissue inhibitor of metalloproteases-1 in breast cancer cells. Cancer Res (1999) 1.59
Inhibition of endoplasmic reticulum (ER)-to-Golgi transport induces relocalization of binding protein (BiP) within the ER to form the BiP bodies. Mol Biol Cell (1994) 1.59
Matrix metalloproteinase 13 (collagenase 3) in human rheumatoid synovium. Arthritis Rheum (1997) 1.58
Autophagy: molecular mechanisms, physiological functions and relevance in human pathology. Cell Mol Life Sci (2004) 1.57
Metalloprotease-dependent protransforming growth factor-alpha ectodomain shedding in the absence of tumor necrosis factor-alpha-converting enzyme. J Biol Chem (2001) 1.54
Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma. Cancer Res (1996) 1.53
In vitro susceptibilities and beta-lactamase production of 53 clinical isolates of Branhamella catarrhalis. Antimicrob Agents Chemother (1985) 1.53
Reconstitution of GTP-binding Sar1 protein function in ER to Golgi transport. J Cell Biol (1991) 1.53
Muscle protein catabolism after severe burn: effects of IGF-1/IGFBP-3 treatment. Ann Surg (1999) 1.50
Expression of collagenase-3 (MMP-13) and collagenase-1 (MMP-1) by transformed keratinocytes is dependent on the activity of p38 mitogen-activated protein kinase. J Cell Sci (2000) 1.50
Identification of a gene required for membrane protein retention in the early secretory pathway. Proc Natl Acad Sci U S A (1993) 1.48
Inhibitors of HSP90 block p95-HER2 signaling in Trastuzumab-resistant tumors and suppress their growth. Oncogene (2009) 1.48
Effect of perorally administered lactobacilli on macrophage activation in mice. Infect Immun (1986) 1.48
Comparison of growth hormone responses to growth hormone-releasing factor and clonidine in women with normal or poor ovarian response to gonadotropin stimulation. Fertil Steril (1993) 1.45
Immune system stimulation by probiotics. J Dairy Sci (1995) 1.44
Rer1p as common machinery for the endoplasmic reticulum localization of membrane proteins. Proc Natl Acad Sci U S A (1997) 1.43
The yeast RER2 gene, identified by endoplasmic reticulum protein localization mutations, encodes cis-prenyltransferase, a key enzyme in dolichol synthesis. Mol Cell Biol (1999) 1.42
NOTCH1 mutations identify a genetic subgroup of chronic lymphocytic leukemia patients with high risk of transformation and poor outcome. Leukemia (2012) 1.41
DNA profiling by arrayCGH in acute myeloid leukemia and myelodysplastic syndromes. Cytogenet Genome Res (2007) 1.41
Collagenase-3 expression in breast myofibroblasts as a molecular marker of transition of ductal carcinoma in situ lesions to invasive ductal carcinomas. Cancer Res (2001) 1.40
Inhibition of GTP hydrolysis by Sar1p causes accumulation of vesicles that are a functional intermediate of the ER-to-Golgi transport in yeast. J Cell Biol (1994) 1.40
[Is the IVF/ICSI sequence with fresh transfer soon to be obsolete? Innovation in MAP: freezing of all embryos]. Gynecol Obstet Fertil (2013) 1.39
A role for a PDZ protein in the early secretory pathway for the targeting of proTGF-alpha to the cell surface. Mol Cell (1999) 1.39
Collagenase-3 (MMP-13) is expressed during human fetal ossification and re-expressed in postnatal bone remodeling and in rheumatoid arthritis. Lab Invest (1997) 1.38
Problems in pharmacological evaluation of patients with paroxysmal atrial fibrillation: clinical analysis of more than 100 consecutive patients. Intern Med (1998) 1.38
Induction of collagenase-3 (MMP-13) expression in human skin fibroblasts by three-dimensional collagen is mediated by p38 mitogen-activated protein kinase. J Biol Chem (1999) 1.37
Purification, gene cloning, and gene disruption of the transcription elongation factor S-II in Saccharomyces cerevisiae. J Biol Chem (1992) 1.37
Endovascular treatment of ruptured dissecting aneurysms aimed at occlusion of the dissected site by using Guglielmi detachable coils. J Neurosurg (1999) 1.37
Collagenase-3 binds to a specific receptor and requires the low density lipoprotein receptor-related protein for internalization. J Biol Chem (1999) 1.36
Mechanism and cleavage specificity of the H-N-H endonuclease colicin E9. J Mol Biol (2001) 1.36
Identification and structural and functional characterization of human enamelysin (MMP-20). Biochemistry (1997) 1.35
Prospective, randomized, controlled study of in vitro fertilization-embryo transfer with a single dose of a luteinizing hormone-releasing hormone (LH-RH) antagonist (cetrorelix) or a depot formula of an LH-RH agonist (triptorelin). Fertil Steril (2000) 1.35
Membrane protein retrieval from the Golgi apparatus to the endoplasmic reticulum (ER): characterization of the RER1 gene product as a component involved in ER localization of Sec12p. Mol Biol Cell (1995) 1.34
Artificial gravity maintains skeletal muscle protein synthesis during 21 days of simulated microgravity. J Appl Physiol (1985) (2009) 1.31
Structure and expression in breast tumors of human TIMP-3, a new member of the metalloproteinase inhibitor family. Cancer Res (1994) 1.30
The GTP-binding Sar1 protein is localized to the early compartment of the yeast secretory pathway. Biochim Biophys Acta (1991) 1.29
Identification and characterization of human MT5-MMP, a new membrane-bound activator of progelatinase a overexpressed in brain tumors. Cancer Res (1999) 1.29
Dm1-MMP, a matrix metalloproteinase from Drosophila with a potential role in extracellular matrix remodeling during neural development. J Biol Chem (2000) 1.29
Induction of matrix metalloproteinase activation cascades based on membrane-type 1 matrix metalloproteinase: associated activation of gelatinase A, gelatinase B and collagenase 3. Biochem J (1998) 1.29
Distinct genomic aberration patterns are found in familial breast cancer associated with different immunohistochemical subtypes. Oncogene (2007) 1.28
The role of lymph node dissection in the treatment of gallbladder carcinoma. Cancer (1997) 1.27
NOTCH inhibition and glucocorticoid therapy in T-cell acute lymphoblastic leukemia. Leukemia (2009) 1.27
Collagenase 2 (MMP-8) expression in murine tissue-remodeling processes. Analysis of its potential role in postpartum involution of the uterus. J Biol Chem (1998) 1.26
Cathepsin Z, a novel human cysteine proteinase with a short propeptide domain and a unique chromosomal location. J Biol Chem (1998) 1.25
Regulation of collagenase-3 expression in human breast carcinomas is mediated by stromal-epithelial cell interactions. Cancer Res (1997) 1.25
Collagenase-3 (MMP-13) expression in chondrosarcoma cells and its regulation by basic fibroblast growth factor. Am J Pathol (1998) 1.24
A genomic view of the complexity of mammalian proteolytic systems. Biochem Soc Trans (2005) 1.24
Multiple roles of Arf1 GTPase in the yeast exocytic and endocytic pathways. Mol Biol Cell (2001) 1.21
Retinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state. Nat Commun (2011) 1.20
Short-term oxandrolone administration stimulates net muscle protein synthesis in young men. J Clin Endocrinol Metab (1999) 1.20
Biogenesis of vacuolar membrane glycoproteins of yeast Saccharomyces cerevisiae. J Biol Chem (1990) 1.20
Rma1, a novel type of RING finger protein conserved from Arabidopsis to human, is a membrane-bound ubiquitin ligase. J Cell Sci (2001) 1.20
Activating mutations in NOTCH1 in acute myeloid leukemia and lineage switch leukemias. Leukemia (2006) 1.19
Human progeroid syndromes, aging and cancer: new genetic and epigenetic insights into old questions. Cell Mol Life Sci (2007) 1.19
An overview of collagenase-3 expression in malignant tumors and analysis of its potential value as a target in antitumor therapies. Clin Chim Acta (2000) 1.19
Identification of ABCC6 pseudogenes on human chromosome 16p: implications for mutation detection in pseudoxanthoma elasticum. Hum Genet (2001) 1.19
Identification and characterization of a novel human matrix metalloproteinase with unique structural characteristics, chromosomal location, and tissue distribution. J Biol Chem (1997) 1.17
The inactive form of a yeast casein kinase I suppresses the secretory defect of the sec12 mutant. Implication of negative regulation by the Hrr25 kinase in the vesicle budding from the endoplasmic reticulum. J Biol Chem (1999) 1.17
Cloning and characterization of human MMP-23, a new matrix metalloproteinase predominantly expressed in reproductive tissues and lacking conserved domains in other family members. J Biol Chem (1999) 1.17
Evaluation of some newer matrix metalloproteinases. Ann N Y Acad Sci (1999) 1.17
Anabolic effects of insulin-like growth factor in combination with insulin-like growth factor binding protein-3 in severely burned adults. J Trauma (1999) 1.16
Genetic interactions among genes involved in the STT4-PKC1 pathway of Saccharomyces cerevisiae. Mol Gen Genet (1994) 1.16
Microsatellite instability due to hMLH1 deficiency is associated with increased cytotoxicity to irinotecan in human colorectal cancer cell lines. Br J Cancer (2008) 1.16