Horizontal gene transfer and the origin of species: lessons from bacteria.

PubWeight™: 3.24‹?› | Rank: Top 1%

🔗 View Article (PMID 10707066)

Published in Trends Microbiol on March 01, 2000

Authors

F de la Cruz1, J Davies

Author Affiliations

1: Departamento de Biolog a Molecular (Unidad Asociada al C.I.B.), Universidad de Cantabria, Santander, Spain. delacruz@medi.unican.es

Articles citing this

(truncated to the top 100)

ACLAME: a CLAssification of Mobile genetic Elements. Nucleic Acids Res (2004) 5.44

The versatile bacterial type IV secretion systems. Nat Rev Microbiol (2003) 4.98

Ecological fitness, genomic islands and bacterial pathogenicity. A Darwinian view of the evolution of microbes. EMBO Rep (2001) 4.78

Integrative and conjugative elements: mosaic mobile genetic elements enabling dynamic lateral gene flow. Nat Rev Microbiol (2010) 3.59

Horizontal gene transfer: a critical view. Proc Natl Acad Sci U S A (2003) 3.27

Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models. BMC Bioinformatics (2006) 3.15

Mobility of plasmids. Microbiol Mol Biol Rev (2010) 2.63

The continuing story of class IIa bacteriocins. Microbiol Mol Biol Rev (2006) 2.39

Mining Bacillus subtilis chromosome heterogeneities using hidden Markov models. Nucleic Acids Res (2002) 2.36

Interactions among strategies associated with bacterial infection: pathogenicity, epidemicity, and antibiotic resistance. Clin Microbiol Rev (2002) 2.20

R391: a conjugative integrating mosaic comprised of phage, plasmid, and transposon elements. J Bacteriol (2002) 2.14

Gene islands integrated into tRNA(Gly) genes confer genome diversity on a Pseudomonas aeruginosa clone. J Bacteriol (2002) 2.14

Where does fission yeast sit on the tree of life? Genome Biol (2000) 2.09

Sequence analysis of the mobile genome island pKLC102 of Pseudomonas aeruginosa C. J Bacteriol (2004) 2.04

The repertoire of ICE in prokaryotes underscores the unity, diversity, and ubiquity of conjugation. PLoS Genet (2011) 2.01

Horizontal gene transfer between bacteria and animals. Trends Genet (2011) 1.96

Detection and characterization of horizontal transfers in prokaryotes using genomic signature. Nucleic Acids Res (2005) 1.86

SIGI: score-based identification of genomic islands. BMC Bioinformatics (2004) 1.61

A tale of two oxidation states: bacterial colonization of arsenic-rich environments. PLoS Genet (2007) 1.59

Enzymes of the shikimic acid pathway encoded in the genome of a basal metazoan, Nematostella vectensis, have microbial origins. Proc Natl Acad Sci U S A (2008) 1.51

Genetic differentiation between sympatric populations of Bacillus cereus and Bacillus thuringiensis. Appl Environ Microbiol (2002) 1.50

VirB7 lipoprotein is exocellular and associates with the Agrobacterium tumefaciens T pilus. J Bacteriol (2001) 1.45

A mosaic pathogenicity island made up of the locus of enterocyte effacement and a pathogenicity island of Escherichia coli O157:H7 is frequently present in attaching and effacing E. coli. Infect Immun (2003) 1.43

Novel recA-Independent Horizontal Gene Transfer in Escherichia coli K-12. PLoS One (2015) 1.43

Something for everyone. Horizontal gene transfer in evolution. EMBO Rep (2000) 1.39

Gene fragments distinguishing an epidemic-associated strain from a virulent prototype strain of Listeria monocytogenes belong to a distinct functional subset of genes and partially cross-hybridize with other Listeria species. Infect Immun (2001) 1.38

The making of a photosynthetic animal. J Exp Biol (2011) 1.37

Disrupting antibiotic resistance propagation by inhibiting the conjugative DNA relaxase. Proc Natl Acad Sci U S A (2007) 1.32

Conjugative DNA transfer induces the bacterial SOS response and promotes antibiotic resistance development through integron activation. PLoS Genet (2010) 1.28

Horizontal gene transfer in the acquisition of novel traits by metazoans. Proc Biol Sci (2014) 1.23

Antibiotic use and population ecology: how you can reduce your "resistance footprint". CMAJ (2009) 1.22

An integrative method for accurate comparative genome mapping. PLoS Comput Biol (2006) 1.22

Heat shock protein 60 sequence comparisons: duplications, lateral transfer, and mitochondrial evolution. Proc Natl Acad Sci U S A (2000) 1.17

Molecular genetic analysis of ICEF, an integrative conjugal element that is present as a repetitive sequence in the chromosome of Mycoplasma fermentans PG18. J Bacteriol (2002) 1.16

The 2010 cholera outbreak in Haiti: how science solved a controversy. PLoS Pathog (2014) 1.15

CRISPR inhibition of prophage acquisition in Streptococcus pyogenes. PLoS One (2011) 1.14

Evolution of conjugation and type IV secretion systems. Mol Biol Evol (2012) 1.14

A degenerate primer MOB typing (DPMT) method to classify gamma-proteobacterial plasmids in clinical and environmental settings. PLoS One (2012) 1.12

Integrating conjugative elements as vectors of antibiotic, mercury, and quaternary ammonium compound resistance in marine aquaculture environments. Antimicrob Agents Chemother (2012) 1.08

Synonymous genes explore different evolutionary landscapes. PLoS Genet (2008) 1.05

Use of long-range repetitive element polymorphism-PCR to differentiate Bacillus anthracis strains. Appl Environ Microbiol (2001) 1.04

Multiple genome alignment for identifying the core structure among moderately related microbial genomes. BMC Genomics (2008) 1.02

Recombination-based in vivo expression technology identifies Helicobacter pylori genes important for host colonization. Infect Immun (2008) 1.00

In planta horizontal transfer of a major pathogenicity effector gene. Appl Environ Microbiol (2007) 1.00

Genetic and functional characterization of the type IV secretion system in Wolbachia. J Bacteriol (2008) 0.99

Relaxase DNA binding and cleavage are two distinguishable steps in conjugative DNA processing that involve different sequence elements of the nic site. J Biol Chem (2010) 0.99

Genetic and structural organization of the aminophenol catabolic operon and its implication for evolutionary process. J Bacteriol (2001) 0.97

Key components of the eight classes of type IV secretion systems involved in bacterial conjugation or protein secretion. Nucleic Acids Res (2014) 0.97

Distant horizontal gene transfer is rare for multiple families of prokaryotic insertion sequences. Mol Genet Genomics (2008) 0.97

Public health evolutionary biology of antimicrobial resistance: priorities for intervention. Evol Appl (2014) 0.97

The mechanism and control of DNA transfer by the conjugative relaxase of resistance plasmid pCU1. Nucleic Acids Res (2010) 0.96

Effect of subinhibitory concentrations of antibiotics on intrachromosomal homologous recombination in Escherichia coli. Antimicrob Agents Chemother (2009) 0.95

OI-57, a genomic island of Escherichia coli O157, is present in other seropathotypes of Shiga toxin-producing E. coli associated with severe human disease. Infect Immun (2010) 0.94

Why bacteriophage encode exotoxins and other virulence factors. Evol Bioinform Online (2007) 0.94

Phylogeny vs genome reshuffling: horizontal gene transfer. Indian J Microbiol (2008) 0.93

Genic incompatibilities in two hybrid bacteriophages. Mol Biol Evol (2009) 0.93

The genome sequence of Propionibacterium acidipropionici provides insights into its biotechnological and industrial potential. BMC Genomics (2012) 0.93

Characterization of a new CAMP factor carried by an integrative and conjugative element in Streptococcus agalactiae and spreading in Streptococci. PLoS One (2012) 0.92

The stb operon balances the requirements for vegetative stability and conjugative transfer of plasmid R388. PLoS Genet (2011) 0.92

Different pathways to acquiring resistance genes illustrated by the recent evolution of IncW plasmids. Antimicrob Agents Chemother (2008) 0.91

Genome evolution and the emergence of fruiting body development in Myxococcus xanthus. PLoS One (2007) 0.91

TnpPred: A Web Service for the Robust Prediction of Prokaryotic Transposases. Comp Funct Genomics (2012) 0.91

An activation domain of plasmid R1 TraI protein delineates stages of gene transfer initiation. Mol Microbiol (2011) 0.90

Presence of pRI1: a small cryptic mobilizable plasmid isolated from Enterococcus faecium of human and animal origin. Curr Microbiol (2008) 0.88

Origins, structures, and functions of circulating DNA in oncology. Cancer Metastasis Rev (2016) 0.87

Evolutionary analysis and lateral gene transfer of two-component regulatory systems associated with heavy-metal tolerance in bacteria. J Mol Evol (2013) 0.87

Horizontal Transfer of the Salmonella enterica Serovar Infantis Resistance and Virulence Plasmid pESI to the Gut Microbiota of Warm-Blooded Hosts. MBio (2016) 0.86

A new evaluation of our life-support system. EMBO Rep (2003) 0.86

CRISPR-Cas systems preferentially target the leading regions of MOBF conjugative plasmids. RNA Biol (2013) 0.86

Silencing by H-NS potentiated the evolution of Salmonella. PLoS Pathog (2014) 0.86

Genomic islands in the Corynebacterium efficiens genome. Appl Environ Microbiol (2005) 0.85

The conjugative DNA translocase TrwB is a structure-specific DNA-binding protein. J Biol Chem (2010) 0.85

Evolution and distribution of saxitoxin biosynthesis in dinoflagellates. Mar Drugs (2013) 0.85

Negative feedback and transcriptional overshooting in a regulatory network for horizontal gene transfer. PLoS Genet (2014) 0.85

Transfer of antibiotic resistance marker genes between lactic acid bacteria in model rumen and plant environments. Appl Environ Microbiol (2009) 0.85

A comparative categorization of protein function encoded in bacterial or archeal genomic islands. J Mol Evol (2005) 0.84

Plasmid R6K replication control. Plasmid (2013) 0.84

Horizontal transfer of erythromycin resistance from Clostridium difficile to Butyrivibrio fibrisolvens. Antimicrob Agents Chemother (2005) 0.83

Monitoring the dissemination of the broad-host-range plasmid pB10 in sediment microcosms by quantitative PCR. Appl Environ Microbiol (2009) 0.83

Accurate localization of the integration sites of two genomic islands at single-nucleotide resolution in the genome of Bacillus cereus ATCC 10987. Comp Funct Genomics (2008) 0.82

The logic layout of the TOL network of Pseudomonas putida pWW0 plasmid stems from a metabolic amplifier motif (MAM) that optimizes biodegradation of m-xylene. BMC Syst Biol (2011) 0.82

Phylogeny rather than ecology or lifestyle biases the construction of Escherichia coli-Shigella genetic exchange communities. Open Biol (2012) 0.82

A novel fold in the TraI relaxase-helicase c-terminal domain is essential for conjugative DNA transfer. J Mol Biol (2008) 0.82

Pathogens protection against the action of disinfectants in multispecies biofilms. Front Microbiol (2015) 0.82

New quantitative methods for measuring plasmid loss rates reveal unexpected stability. Plasmid (2013) 0.82

Identification of a metagenomic gene cluster containing a new class A beta-lactamase and toxin-antitoxin systems. Microbiologyopen (2013) 0.82

A high security double lock and key mechanism in HUH relaxases controls oriT-processing for plasmid conjugation. Nucleic Acids Res (2014) 0.80

Investigating the impact of bisphosphonates and structurally related compounds on bacteria containing conjugative plasmids. Biochem Biophys Res Commun (2012) 0.80

The Dynamics of Genetic Interactions between Vibrio metoecus and Vibrio cholerae, Two Close Relatives Co-Occurring in the Environment. Genome Biol Evol (2015) 0.79

Across genus plasmid transformation between Bacillus subtilis and Escherichia coli and the effect of Escherichia coli on the transforming ability of free plasmid DNA. Curr Microbiol (2007) 0.79

Microbiome Selection Could Spur Next-Generation Plant Breeding Strategies. Front Microbiol (2016) 0.79

Comparative genomic and phylogenetic analyses of Gammaproteobacterial glg genes traced the origin of the Escherichia coli glycogen glgBXCAP operon to the last common ancestor of the sister orders Enterobacteriales and Pasteurellales. PLoS One (2015) 0.78

Functions and origin of plasmids in Erwinia species that are pathogenic to or epiphytically associated with pome fruit trees. Trees (Berl West) (2011) 0.78

Enhanced production of recombinant proteins with Corynebacterium glutamicum by deletion of insertion sequences (IS elements). Microb Cell Fact (2015) 0.78

The ecology of bacterial genes and the survival of the new. Int J Evol Biol (2012) 0.78

Plasmid conjugation from proteobacteria as evidence for the origin of xenologous genes in cyanobacteria. J Bacteriol (2014) 0.78

Effects of subminimum inhibitory concentrations of antibiotics on the Pasteurella multocida proteome: a systems approach. Comp Funct Genomics (2008) 0.78

Diversity of Culturable Thermophilic Actinobacteria in Hot Springs in Tengchong, China and Studies of their Biosynthetic Gene Profiles. Microb Ecol (2016) 0.77

Prevalence of antibiotic-resistant bacteria in three different aquatic environments over three seasons. Environ Monit Assess (2014) 0.77

Repression/depression of conjugative plasmids and their influence on the mutation-selection balance in static environments. PLoS One (2014) 0.77

Articles by these authors

(truncated to the top 100)

Transposition of R factor genes to bacteriophage lambda. Proc Natl Acad Sci U S A (1975) 9.28

Plasmid-encoded hygromycin B resistance: the sequence of hygromycin B phosphotransferase gene and its expression in Escherichia coli and Saccharomyces cerevisiae. Gene (1983) 8.79

Plasmid-determined resistance to antimicrobial agents. Annu Rev Microbiol (1978) 8.35

Mechanisms of antibiotic resistance in bacteria. Annu Rev Biochem (1973) 7.08

Insulin-IGF2 region on chromosome 11p encodes a gene implicated in HLA-DR4-dependent diabetes susceptibility. Nature (1991) 6.17

The problems of drug-resistant pathogenic bacteria. R factors: biochemical mechanisms of resistance to aminoglycoside antibiotics. Ann N Y Acad Sci (1971) 5.52

Aminoglycoside antibiotic-inactivating enzymes in actinomycetes similar to those present in clinical isolates of antibiotic-resistant bacteria. Proc Natl Acad Sci U S A (1973) 5.20

Enzymatic acetylation of aminoglycoside antibiotics by Escherichia coli carrying an R factor. Biochemistry (1971) 5.01

"Infectious" transplantation tolerance. Science (1993) 4.98

Transposition of an antibiotic resistance element in mycobacteria. Nature (1990) 4.85

The DNA sequence and analysis of human chromosome 6. Nature (2003) 4.75

Expression of a transposable antibiotic resistance element in Saccharomyces. Nature (1980) 4.66

Antibiotic inhibitors of the bacterial ribosome. Bacteriol Rev (1968) 4.56

Misreading of RNA codewords induced by aminoglycoside antibiotics. Mol Pharmacol (1965) 4.45

Detection of an unstable fragment of DNA specific to individuals with myotonic dystrophy. Nature (1992) 4.44

Single vs weekly courses of antenatal corticosteroids for women at risk of preterm delivery: A randomized controlled trial. JAMA (2001) 4.30

Distribution of thiols in microorganisms: mycothiol is a major thiol in most actinomycetes. J Bacteriol (1996) 3.98

A distinctive class of integron in the Vibrio cholerae genome. Science (1998) 3.86

Gentamicin resistance in strains of Pseudomonas aeruginosa mediated by enzymatic N-acetylation of the deoxystreptamine moiety. Biochemistry (1972) 3.56

Aminoglycoside antibiotics: inactivation by phosphorylation in Escherichia coli carrying R factors. J Bacteriol (1969) 3.52

On the evolution of Tn21-like multiresistance transposons: sequence analysis of the gene (aacC1) for gentamicin acetyltransferase-3-I(AAC(3)-I), another member of the Tn21-based expression cassette. Mol Gen Genet (1989) 3.46

The isolation and partial characterization of a new restriction endonuclease from Providencia stuartii. Nucleic Acids Res (1976) 3.30

R-factor mediated gentamicin resistance: A new enzyme which modifies aminoglycoside antibiotics. FEBS Lett (1971) 3.28

Genetic mapping of the regulator and operator genes of the lac operon. J Mol Biol (1968) 3.19

Enzymatic Adenylylation of Streptomycin and Spectinomycin by R-Factor-Resistant Escherichia coli. Infect Immun (1970) 3.02

Phenotypic suppression and misreading Saccharomyces cerevisiae. Nature (1979) 3.01

An SNP map of human chromosome 22. Nature (2000) 2.99

Resistance of Haemophilus influenzae to trimethoprim. Br Med J (1972) 2.89

Gene transfer between distantly related bacteria. Annu Rev Genet (1991) 2.88

A placental clock controlling the length of human pregnancy. Nat Med (1995) 2.86

Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae. Genetics (1997) 2.81

The evolutionary history of chromosomal super-integrons provides an ancestry for multiresistant integrons. Proc Natl Acad Sci U S A (2001) 2.77

Mechanism of inhibition of eukaryotic protein synthesis by trichothecene fungal toxins. Proc Natl Acad Sci U S A (1974) 2.67

Inhibition of protein synthesis by spectinomycin. Science (1965) 2.54

Enzymatic modification of aminoglycoside antibiotics: 3-N-acetyltransferase with broad specificity that determines resistance to the novel aminoglycoside apramycin. Antimicrob Agents Chemother (1978) 2.53

Nasal acquisition of Staphylococcus aureus in a subdivided and mechanically ventilated ward: endemic prevalence of a single staphylococcal strain. J Hyg (Lond) (1970) 2.48

Enzymatic inactivation of streptomycin by R factor-resistant Escherichia coli. Nature (1968) 2.45

Antibiotic inhibition of group I ribozyme function. Nature (1991) 2.44

The DNA sequence and biological annotation of human chromosome 1. Nature (2006) 2.42

The genetics of bacterial ribosomes. Annu Rev Genet (1972) 2.41

Misreading of ribonucleic acid code words induced by aminoglycoside antibiotics. The effect of drug concentration. J Biol Chem (1968) 2.38

Enzymatic acetylation as a means of determining serum aminoglycoside concentrations. Antimicrob Agents Chemother (1973) 2.37

Increased rates of illness and death from asthma in Canada. CMAJ (1987) 2.31

A new selective agent for eukaryotic cloning vectors. Am J Trop Med Hyg (1980) 2.28

Synthetic D(-)penicillamine in rheumatoid arthritis. Double-blind controlled study of a high and low dosage regimen. Ann Rheum Dis (1975) 2.27

Effective dose from cone beam CT examinations in dentistry. Br J Radiol (2008) 2.25

Plasmid-medicated aminoglycoside phosphotransferase of broad substrate range that phosphorylates amikacin. Antimicrob Agents Chemother (1977) 2.22

CFTR biomarkers: time for promotion to surrogate end-point. Eur Respir J (2012) 2.11

Enzymatic modification of aminoglycoside antibiotics: a new 3-N-acetylating enzyme from a Pseudomonas aeruginosa isolate. Antimicrob Agents Chemother (1976) 2.10

Antibiotic resistance in the ECOR collection: integrons and identification of a novel aad gene. Antimicrob Agents Chemother (2000) 2.09

Spinal interneurone excitation by conformationally restricted analogues of L-glutamic acid. Nature (1974) 2.09

2-Amino-5-phosphonovalerate (2APV), a potent and selective antagonist of amino acid-induced and synaptic excitation. Neurosci Lett (1981) 2.08

Microcloning reveals a high frequency of repetitive sequences characteristic of chromosome 4 and the beta-heterochromatin of Drosophila melanogaster. Proc Natl Acad Sci U S A (1988) 2.06

Glial-cell-line-derived neurotrophic factor is required for bud initiation from ureteric epithelium. Development (1997) 2.05

Detection of antigen-antibody binding events with the atomic force microscope. Biochemistry (1997) 2.05

Mode of action of thiolutin, an inhibitor of macromolecular synthesis in Saccharomyces cerevisiae. Antimicrob Agents Chemother (1973) 2.04

Cytokine gene expression in Helicobacter pylori associated antral gastritis. Gut (1994) 1.97

Clinical features of fifteen patients with the hypereosinophilic syndrome. Q J Med (1983) 1.96

Interaction of antibiotics with A- and P-site-specific bases in 16S ribosomal RNA. EMBO J (1991) 1.96

A study of iterative type II polyketide synthases, using bacterial genes cloned from soil DNA: a means to access and use genes from uncultured microorganisms. J Bacteriol (1997) 1.95

Effect of spectinomycin on polypeptide synthesis in extracts of Escherichia coli. J Mol Biol (1967) 1.93

Trichodermin resistance--mutation affecting eukaryotic ribosomes. Nature (1974) 1.90

Comparison of azathioprine, cyclophosphamide, and gold in treatment of rheumatoid arthritis. Br Med J (1974) 1.87

Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord. Brain Res (1982) 1.86

Enzymatic modification of aminoglycoside antibiotics: a new 6'-N-acetylating enzyme from a Pseudomonas aeruginosa isolate. Antimicrob Agents Chemother (1976) 1.81

Morbid obesity in the medical ICU. Chest (2001) 1.79

Antibiotic resistance in microbes. Cell Mol Life Sci (1999) 1.77

Selective antagonism of amino acid-induced and synaptic excitation in the cat spinal cord. J Physiol (1979) 1.76

Plasmid-determined fusidic acid resistance in the Enterobacteriaceae. J Gen Microbiol (1974) 1.74

Ribosomal Protein Conferring Sensitivity to the Antibiotic Spectinomycin in Escherichia coli. Science (1969) 1.73

The geographic variation of cancer incidence in Ontario. Am J Public Health (1994) 1.72

CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]D-AP5 binding sites on brain membranes and anticonvulsant activity. Brain Res (1986) 1.70

Cationic lipid-mediated CFTR gene transfer to the lungs and nose of patients with cystic fibrosis: a double-blind placebo-controlled trial. Lancet (1999) 1.69

Audit of mortality in upper gastrointestinal bleeding. Postgrad Med J (1989) 1.68

Delayed diagnosis in non-insulin dependent diabetes mellitus. BMJ (1992) 1.68

A further study of misreading of codons induced by streptomycin and neomycin using ribopolynucleotides containing two nucleotides in alternating sequence as templates. J Mol Biol (1966) 1.65

Mechanisms of resistance to aminoglycosides. Am J Med (1977) 1.65

Public awareness of the symptoms of diabetes mellitus. Diabet Med (1991) 1.64

A comparative study on the inhibitory actions of chloramphenicol, thiamphenicol and some fluorinated derivatives. J Antimicrob Chemother (1990) 1.63

Nosocomial infections with gentamicin-resistant Staphylococcus aureus: plamid analysis as an epidemiologic tool. J Infect Dis (1979) 1.63

Cardiovascular features of 11 patients with eosinophilic endomyocardial disease. Q J Med (1983) 1.62

Ethics committees and health services research. J Public Health Med (1990) 1.60

In a map for human life, count the microbes, too. Science (2001) 1.60

The structure of U17 isolated from Streptomyces clavuligerus and its properties as an antioxidant thiol. Eur J Biochem (1995) 1.59

A genetic and biochemical study of streptomycin- and spectinomycin-resistance in Salmonella typhimurium. Mol Gen Genet (1971) 1.58

Unstable DNA may be responsible for the incomplete penetrance of the myotonic dystrophy phenotype. Hum Mol Genet (1992) 1.57

Nasal acquisition of Staphylococcus aureus in partly divided wards. J Hyg (Lond) (1971) 1.57

Aminoglycoside-modifying enzyme of an antibiotic-producing bacterium acts as a determinant of antibiotic resistance in Escherichia coli. Proc Natl Acad Sci U S A (1977) 1.57

Anderson-Fabry disease: clinical manifestations of disease in female heterozygotes. J Inherit Metab Dis (2001) 1.56

Genetic basis for colonial variation in Neisseria gonorrhoeae. J Bacteriol (1979) 1.55

Endomyocardial complications of the Churg-Strauss syndrome. Postgrad Med J (1985) 1.54

Predicting risk of preterm delivery by second-trimester measurement of maternal plasma corticotropin-releasing hormone and alpha-fetoprotein concentrations. Am J Obstet Gynecol (1999) 1.53

Intramedullary pressure and bone marrow fat extravasation in reamed and unreamed femoral nailing. J Orthop Res (1999) 1.53

Novel natural products from soil DNA libraries in a streptomycete host. Org Lett (2000) 1.52

Aminoglycoside resistance in bacteria medicated by gentamicin acetyltransferase II, an enzyme modifying the 2'-amino group of aminoglycoside antibiotics. Biochemistry (1974) 1.52

Use of antibiotic prophylaxis in elective inguinal hernia repair in adults in London and south-east England: a cross-sectional survey. Hernia (2013) 1.50

An assessment of clinically optimal gold marker length and diameter for pelvic radiotherapy verification using an amorphous silicon flat panel electronic portal imaging device. Br J Radiol (2005) 1.50

Transfer of plasmid RSF1010 by conjugation from Escherichia coli to Streptomyces lividans and Mycobacterium smegmatis. J Bacteriol (1991) 1.49

Structure-activity relationships among the aminoglycoside antibiotics: role of hydroxyl and amino groups. Antimicrob Agents Chemother (1973) 1.46

Anti-L-selectin antibody treatment of hemorrhagic-traumatic shock in baboons. Crit Care Med (1999) 1.45