Published in Biochemistry on March 21, 2000
Informational complexity and functional activity of RNA structures. J Am Chem Soc (2004) 2.19
Selection of an improved RNA polymerase ribozyme with superior extension and fidelity. RNA (2007) 2.05
In vitro selection, characterization, and application of deoxyribozymes that cleave RNA. Nucleic Acids Res (2005) 1.51
De novo synthesis and development of an RNA enzyme. Proc Natl Acad Sci U S A (2004) 1.24
The three-dimensional architecture of the class I ligase ribozyme. RNA (2004) 1.17
New ligase-derived RNA polymerase ribozymes. RNA (2005) 1.16
Solution structure of an informationally complex high-affinity RNA aptamer to GTP. RNA (2006) 1.06
The promise and peril of continuous in vitro evolution. J Mol Evol (2005) 1.00
Direct selection of trans-acting ligase ribozymes by in vitro compartmentalization. RNA (2005) 0.99
An RNA toolbox for single-molecule force spectroscopy studies. Nucleic Acids Res (2007) 0.96
Accumulation of deleterious mutations in small abiotic populations of RNA. Genetics (2006) 0.95
Zeptomole detection of a viral nucleic acid using a target-activated ribozyme. RNA (2003) 0.91
Continuous in vitro evolution of ribozymes that operate under conditions of extreme pH. J Mol Evol (2003) 0.91
A class I ligase ribozyme with reduced Mg2+ dependence: Selection, sequence analysis, and identification of functional tertiary interactions. RNA (2009) 0.90
Two independently selected capping ribozymes share similar substrate requirements. RNA (2006) 0.86
Recombination during in vitro evolution. J Mol Evol (2005) 0.85
RNA-directed construction of structurally complex and active ligase ribozymes through recombination. RNA (2005) 0.85
Characterization of the B6.61 polymerase ribozyme accessory domain. RNA (2011) 0.81
Partitioning the fitness components of RNA populations evolving in vitro. PLoS One (2013) 0.75
Ribozymes: analytical solution of the one-substrate, two-intermediate reversible scheme for enzyme reactions. J Biol Phys (2007) 0.75
An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science (2001) 44.16
RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell (2000) 20.32
Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev (1999) 8.21
Synthesizing life. Nature (2001) 6.55
RNA-catalyzed RNA polymerization: accurate and general RNA-templated primer extension. Science (2001) 4.53
The guanosine binding site of the Tetrahymena ribozyme. Nature (1989) 4.43
Phylogenetic analysis of tmRNA secondary structure. RNA (1996) 2.95
RNA-catalysed nucleotide synthesis. Nature (1998) 2.80
Structurally complex and highly active RNA ligases derived from random RNA sequences. Science (1995) 2.53
One sequence, two ribozymes: implications for the emergence of new ribozyme folds. Science (2000) 2.53
Resuming translation on tmRNA: a unique mode of determining a reading frame. EMBO J (1999) 2.14
RNA-catalysed RNA polymerization using nucleoside triphosphates. Nature (1996) 1.84
PCR product with strands of unequal length. Nucleic Acids Res (1995) 1.65
The PUMILIO-RNA interaction: a single RNA-binding domain monomer recognizes a bipartite target sequence. Biochemistry (1999) 1.63
Accessing rare activities from random RNA sequences: the importance of the length of molecules in the starting pool. Chem Biol (1997) 1.58
Reverse transcriptase reads through a 2'-5'linkage and a 2'-thiophosphate in a template. Nucleic Acids Res (1995) 1.57
The secondary structure and sequence optimization of an RNA ligase ribozyme. Nucleic Acids Res (1995) 1.45
The hammerhead cleavage reaction in monovalent cations. RNA (2001) 1.44
Selection in vitro of novel ribozymes from a partially randomized U2 and U6 snRNA library. EMBO J (1998) 1.43
Kinetic and mechanistic analysis of nonenzymatic, template-directed oligoribonucleotide ligation. J Am Chem Soc (1996) 1.41
Bioactive and nuclease-resistant L-DNA ligand of vasopressin. Proc Natl Acad Sci U S A (1997) 1.40
The tmRNA Website. Nucleic Acids Res (1998) 1.37
Nonenzymatic, template-directed ligation of oligoribonucleotides is highly regioselective for the formation of 3'-5' phosphodiester bonds. J Am Chem Soc (1996) 1.30
1H NMR studies of the high-affinity Rev binding site of the Rev responsive element of HIV-1 mRNA: base pairing in the core binding element. Biochemistry (1994) 1.18
A ribozyme selected from variants of U6 snRNA promotes 2',5'-branch formation. RNA (2001) 0.98
Selection and design of high-affinity RNA ligands for HIV-1 Rev. Gene (1993) 0.95
Transluminal angioplasty of complete iliac obstructions. AJR Am J Roentgenol (1986) 0.93
Recognition of nucleoside triphosphates during RNA-catalyzed primer extension. Biochemistry (2000) 0.89
Oxidant-increased endothelial permeability: prevention with phosphodiesterase inhibition vs. cAMP production. J Appl Physiol (1985) (2000) 0.75
RNA-catalysed RNA polymerization using nucleoside triphosphates. Nature (1996) 0.75