Published in Nucleic Acids Res on August 25, 1995
Informational complexity and functional activity of RNA structures. J Am Chem Soc (2004) 2.19
Selection of an improved RNA polymerase ribozyme with superior extension and fidelity. RNA (2007) 2.05
Design and optimization of effector-activated ribozyme ligases. Nucleic Acids Res (2000) 1.43
Selection in vitro of novel ribozymes from a partially randomized U2 and U6 snRNA library. EMBO J (1998) 1.43
A complex ligase ribozyme evolved in vitro from a group I ribozyme domain. Proc Natl Acad Sci U S A (1999) 1.33
Crystal structure of the catalytic core of an RNA-polymerase ribozyme. Science (2009) 1.27
De novo synthesis and development of an RNA enzyme. Proc Natl Acad Sci U S A (2004) 1.24
The three-dimensional architecture of the class I ligase ribozyme. RNA (2004) 1.17
Improved polymerase ribozyme efficiency on hydrophobic assemblies. RNA (2008) 1.14
Optimization and optimality of a short ribozyme ligase that joins non-Watson-Crick base pairings. RNA (2001) 1.05
Consistent global structures of complex RNA states through multidimensional chemical mapping. Elife (2015) 1.01
Direct selection of trans-acting ligase ribozymes by in vitro compartmentalization. RNA (2005) 0.99
A ribozyme selected from variants of U6 snRNA promotes 2',5'-branch formation. RNA (2001) 0.98
Combinatorial minimization and secondary structure determination of a nucleotide synthase ribozyme. RNA (2003) 0.97
Structure-guided engineering of the regioselectivity of RNA ligase ribozymes. J Am Chem Soc (2009) 0.96
Closing the circle: replicating RNA with RNA. Cold Spring Harb Perspect Biol (2010) 0.96
Zeptomole detection of a viral nucleic acid using a target-activated ribozyme. RNA (2003) 0.91
A class I ligase ribozyme with reduced Mg2+ dependence: Selection, sequence analysis, and identification of functional tertiary interactions. RNA (2009) 0.90
Enhanced functional potential of nucleic acid aptamer libraries patterned to increase secondary structure. J Am Chem Soc (2010) 0.90
Polymerase ribozyme efficiency increased by G/T-rich DNA oligonucleotides. RNA (2011) 0.85
RNA-directed construction of structurally complex and active ligase ribozymes through recombination. RNA (2005) 0.85
Characterization of long RNA-cleaving deoxyribozymes with short catalytic cores: the effect of excess sequence elements on the outcome of in vitro selection. Nucleic Acids Res (2006) 0.82
Synthetic shuffling and in vitro selection reveal the rugged adaptive fitness landscape of a kinase ribozyme. RNA (2013) 0.81
Sequence analysis of an artificial family of RNA-binding peptides. Protein Sci (2002) 0.75
Development of a Functionally Minimized Mutant of the R3C Ligase Ribozyme Offers Insight into the Plausibility of the RNA World Hypothesis. Biology (Basel) (2014) 0.75
Evolution of an inhibitory RNA aptamer against T7 RNA polymerase. FEBS Open Bio (2012) 0.75
Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science (1990) 35.96
Detailed analysis of the higher-order structure of 16S-like ribosomal ribonucleic acids. Microbiol Rev (1983) 23.08
Modelling of the three-dimensional architecture of group I catalytic introns based on comparative sequence analysis. J Mol Biol (1990) 10.85
Isolation of new ribozymes from a large pool of random sequences [see comment]. Science (1993) 6.08
CUUCGG hairpins: extraordinarily stable RNA secondary structures associated with various biochemical processes. Proc Natl Acad Sci U S A (1988) 5.50
HIV-1 Rev regulation involves recognition of non-Watson-Crick base pairs in viral RNA. Cell (1991) 4.43
Detailed molecular model for transfer ribonucleic acid. Nature (1969) 3.81
RNA pseudoknots that inhibit human immunodeficiency virus type 1 reverse transcriptase. Proc Natl Acad Sci U S A (1992) 3.46
Structural conventions for group I introns. Nucleic Acids Res (1987) 3.12
In vitro selection of RNAs that undergo autolytic cleavage with Pb2+. Biochemistry (1992) 2.60
Structurally complex and highly active RNA ligases derived from random RNA sequences. Science (1995) 2.53
U1-snRNP-A protein selects a ten nucleotide consensus sequence from a degenerate RNA pool presented in various structural contexts. Nucleic Acids Res (1991) 2.49
Essential nucleotide sequences and secondary structure elements of the hairpin ribozyme. EMBO J (1993) 1.69
In vitro genetic analysis of the Tetrahymena self-splicing intron. Nature (1990) 1.62
In vitro selection of active hairpin ribozymes by sequential RNA-catalyzed cleavage and ligation reactions. Genes Dev (1992) 1.42
In vitro evolution of nucleic acids. Curr Opin Struct Biol (1994) 1.22
In vitro selection and evolution of RNA: applications for catalytic RNA, molecular recognition, and drug discovery. FASEB J (1993) 1.11
In vitro genetic analysis of the hinge region between helical elements P5-P4-P6 and P7-P3-P8 in the sunY group I self-splicing intron. J Mol Biol (1994) 1.07
An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science (2001) 44.16
RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell (2000) 20.32
Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev (1999) 8.21
Synthesizing life. Nature (2001) 6.55
RNA-catalyzed RNA polymerization: accurate and general RNA-templated primer extension. Science (2001) 4.53
The guanosine binding site of the Tetrahymena ribozyme. Nature (1989) 4.43
Phylogenetic analysis of tmRNA secondary structure. RNA (1996) 2.95
RNA-catalysed nucleotide synthesis. Nature (1998) 2.80
Structurally complex and highly active RNA ligases derived from random RNA sequences. Science (1995) 2.53
One sequence, two ribozymes: implications for the emergence of new ribozyme folds. Science (2000) 2.53
Resuming translation on tmRNA: a unique mode of determining a reading frame. EMBO J (1999) 2.14
RNA-catalysed RNA polymerization using nucleoside triphosphates. Nature (1996) 1.84
PCR product with strands of unequal length. Nucleic Acids Res (1995) 1.65
The PUMILIO-RNA interaction: a single RNA-binding domain monomer recognizes a bipartite target sequence. Biochemistry (1999) 1.63
Accessing rare activities from random RNA sequences: the importance of the length of molecules in the starting pool. Chem Biol (1997) 1.58
Reverse transcriptase reads through a 2'-5'linkage and a 2'-thiophosphate in a template. Nucleic Acids Res (1995) 1.57
The hammerhead cleavage reaction in monovalent cations. RNA (2001) 1.44
Selection in vitro of novel ribozymes from a partially randomized U2 and U6 snRNA library. EMBO J (1998) 1.43
Kinetic and mechanistic analysis of nonenzymatic, template-directed oligoribonucleotide ligation. J Am Chem Soc (1996) 1.41
Bioactive and nuclease-resistant L-DNA ligand of vasopressin. Proc Natl Acad Sci U S A (1997) 1.40
The tmRNA Website. Nucleic Acids Res (1998) 1.37
Nonenzymatic, template-directed ligation of oligoribonucleotides is highly regioselective for the formation of 3'-5' phosphodiester bonds. J Am Chem Soc (1996) 1.30
Kinetic framework for ligation by an efficient RNA ligase ribozyme. Biochemistry (2000) 1.23
1H NMR studies of the high-affinity Rev binding site of the Rev responsive element of HIV-1 mRNA: base pairing in the core binding element. Biochemistry (1994) 1.18
A ribozyme selected from variants of U6 snRNA promotes 2',5'-branch formation. RNA (2001) 0.98
Selection and design of high-affinity RNA ligands for HIV-1 Rev. Gene (1993) 0.95
Recognition of nucleoside triphosphates during RNA-catalyzed primer extension. Biochemistry (2000) 0.89
RNA-catalysed RNA polymerization using nucleoside triphosphates. Nature (1996) 0.75