Published in J Biol Chem on September 22, 2000
Topology of the membrane-associated hepatitis C virus protein NS4B. J Virol (2003) 2.37
Two translocating hydrophilic segments of a nascent chain span the ER membrane during multispanning protein topogenesis. J Cell Biol (2007) 1.20
Integration of Shaker-type K+ channel, KAT1, into the endoplasmic reticulum membrane: synergistic insertion of voltage-sensing segments, S3-S4, and independent insertion of pore-forming segments, S5-P-S6. Proc Natl Acad Sci U S A (2001) 1.06
Switching the sorting mode of membrane proteins from cotranslational endoplasmic reticulum targeting to posttranslational mitochondrial import. Mol Biol Cell (2005) 0.97
Biogenesis of CFTR and other polytopic membrane proteins: new roles for the ribosome-translocon complex. J Membr Biol (2004) 0.93
Translocation of a long amino-terminal domain through ER membrane by following signal-anchor sequence. EMBO J (2005) 0.86
Topology of transmembrane segments 1-4 in the human chloride/bicarbonate anion exchanger 1 (AE1) by scanning N-glycosylation mutagenesis. Biochem J (2005) 0.84
Understanding the biogenesis of polytopic integral membrane proteins. J Membr Biol (2003) 0.81
Viroporins, Examples of the Two-Stage Membrane Protein Folding Model. Viruses (2015) 0.75
Effect of the Southeast Asian Ovalocytosis Deletion on the Conformational Dynamics of the Signal-Anchor Transmembrane Segment 1 of the Red Cell Anion Exchanger 1 (AE1, Band 3, SLC4A1). Biochemistry (2017) 0.75
Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia. Leukemia (2004) 3.59
Characterization of paired tumor and non-tumor cell lines established from patients with breast cancer. Int J Cancer (1998) 3.12
Three-year follow-up after implantation of metallic coronary-artery stents. N Engl J Med (1996) 2.95
Structural basis of presequence recognition by the mitochondrial protein import receptor Tom20. Cell (2000) 2.84
Mitochondrial DNA damage and dysfunction associated with oxidative stress in failing hearts after myocardial infarction. Circ Res (2001) 2.62
Characterization of the signal that directs Tom20 to the mitochondrial outer membrane. J Cell Biol (2000) 2.16
Ile50Val variant of IL4R alpha upregulates IgE synthesis and associates with atopic asthma. Nat Genet (1998) 2.12
Genetic variants of IL-13 signalling and human asthma and atopy. Hum Mol Genet (2000) 2.08
p32 protein, a splicing factor 2-associated protein, is localized in mitochondrial matrix and is functionally important in maintaining oxidative phosphorylation. J Biol Chem (1997) 2.03
Restenosis after percutaneous transluminal coronary angioplasty: pathologic observations in 20 patients. J Am Coll Cardiol (1991) 2.03
Positive and negative regulation of myogenic differentiation of C2C12 cells by isoforms of the multiple homeodomain zinc finger transcription factor ATBF1. J Biol Chem (2001) 1.95
Topological rules for membrane protein assembly in eukaryotic cells. J Biol Chem (1997) 1.83
Intraoperative monitoring of pressure-volume loops of the left ventricle in pericardectomy for constrictive pericarditis. J Thorac Cardiovasc Surg (1996) 1.83
Functions of signal and signal-anchor sequences are determined by the balance between the hydrophobic segment and the N-terminal charge. Proc Natl Acad Sci U S A (1992) 1.72
Molecular cloning and sequencing of cDNA for yeast porin, an outer mitochondrial membrane protein: a search for targeting signal in the primary structure. EMBO J (1985) 1.67
Prevention of acute liver failure in rats with reversibly immortalized human hepatocytes. Science (2000) 1.64
Molten globule of cytochrome c studied by small angle X-ray scattering. J Mol Biol (1993) 1.63
In vitro synthesis and integration into mitochondria of porin, a major protein of the outer mitochondrial membrane of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1982) 1.62
A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines. Biochem Biophys Res Commun (2000) 1.62
A short amino-terminal segment of microsomal cytochrome P-450 functions both as an insertion signal and as a stop-transfer sequence. EMBO J (1987) 1.61
Chymase-dependent angiotensin II formation in human vascular tissue. Circulation (1999) 1.60
Inhibitory effects of antioxidants on neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-alpha and angiotensin II. Circulation (1998) 1.57
Restenosis after successful percutaneous transluminal coronary angioplasty: serial angiographic follow-up of 229 patients. J Am Coll Cardiol (1988) 1.55
A reverse-sandwich ELISA for IgG antibody to a pollen allergen. J Allergy Clin Immunol (1988) 1.52
Evidence in support of a four transmembrane-pore-transmembrane topology model for the Arabidopsis thaliana Na+/K+ translocating AtHKT1 protein, a member of the superfamily of K+ transporters. Proc Natl Acad Sci U S A (2001) 1.50
Systematic analysis of stop-transfer sequence for microsomal membrane. J Biol Chem (1991) 1.50
TOM22, a core component of the mitochondria outer membrane protein translocation pore, is a mitochondrial receptor for the proapoptotic protein Bax. Cell Death Differ (2006) 1.47
The four cytoplasmically made subunits of yeast mitochondrial cytochrome c oxidase are synthesized individually and not as a polyprotein. Proc Natl Acad Sci U S A (1980) 1.46
Association between carotid stenosis or lacunar infarction and incident dementia in patients with vascular risk factors. Eur J Neurol (2014) 1.44
Reconstitution of the initial steps of mitochondrial protein import. Nature (1995) 1.44
A mitochondrial import factor purified from rat liver cytosol is an ATP-dependent conformational modulator for precursor proteins. EMBO J (1993) 1.42
Cloning and characterization of the Hakata antigen, a member of the ficolin/opsonin p35 lectin family. J Biol Chem (1998) 1.40
Hepatocyte growth factor induces differentiation of adult rat bone marrow cells into a hepatocyte lineage in vitro. Biochem Biophys Res Commun (2000) 1.40
Active and passive mechanical characteristics of bovine mesenteric lymphatics. Am J Physiol (1980) 1.39
Initial and follow-up results of the ACS multi-link stent: a single center experience. Cathet Cardiovasc Diagn (1998) 1.39
Reconstitution of hepatic microsomal stearoyl-coenzyme A desaturase system from solubilized components. J Biochem (1972) 1.37
Clinical and angiographic follow-up after single long GFX coronary stent implantation. Catheter Cardiovasc Interv (2000) 1.37
Treatment of pyogenic granuloma with a sclerosing agent. Dermatol Surg (2001) 1.37
Differentiation of early plasma cells on bone marrow stromal cells requires interleukin-6 for escaping from apoptosis. Blood (1995) 1.36
Metaxin is a component of a preprotein import complex in the outer membrane of the mammalian mitochondrion. J Biol Chem (1997) 1.32
Structure and calcium-binding properties of Frq1, a novel calcium sensor in the yeast Saccharomyces cerevisiae. Biochemistry (2000) 1.32
Growth of measles virus in epithelial and lymphoid tissues of cynomolgus monkeys. Microbiol Immunol (1986) 1.31
Trehalose levels and survival ratio of freeze-tolerant versus freeze-sensitive yeasts. Appl Environ Microbiol (1990) 1.30
Interaction of mitochondrial targeting signals with acidic receptor domains along the protein import pathway: evidence for the 'acid chain' hypothesis. EMBO J (1998) 1.30
REIC/Dkk-3 overexpression downregulates P-glycoprotein in multidrug-resistant MCF7/ADR cells and induces apoptosis in breast cancer. Cancer Gene Ther (2008) 1.28
Characterization of rat TOM40, a central component of the preprotein translocase of the mitochondrial outer membrane. J Biol Chem (2000) 1.27
Antiproliferative activity of REIC/Dkk-3 and its significant down-regulation in non-small-cell lung carcinomas. Biochem Biophys Res Commun (2001) 1.27
Importance of the proline-rich region following signal-anchor sequence in the formation of correct conformation of microsomal cytochrome P-450s. J Biochem (1993) 1.25
Forced transmembrane orientation of hydrophilic polypeptide segments in multispanning membrane proteins. Mol Cell (1998) 1.25
Signal recognition particle is required for co-translational insertion of cytochrome P-450 into microsomal membranes. Proc Natl Acad Sci U S A (1984) 1.22
Cutting edge: dominant effect of Ile50Val variant of the human IL-4 receptor alpha-chain in IgE synthesis. J Immunol (1999) 1.20
Increase in resistance of methicillin-resistant Staphylococcus aureus to beta-lactams caused by mutations conferring resistance to benzalkonium chloride, a disinfectant widely used in hospitals. Antimicrob Agents Chemother (1999) 1.19
The amino-terminal structures that determine topological orientation of cytochrome P-450 in microsomal membrane. EMBO J (1990) 1.19
Phospholipids from the free-living nematode Caenorhabditis elegans. Lipids (1993) 1.18
Urinary oligosaccharides of mannosidosis. J Biol Chem (1980) 1.18
MSF, a novel cytoplasmic chaperone which functions in precursor targeting to mitochondria. EMBO J (1994) 1.18
A new human chondrosarcoma cell line (OUMS-27) that maintains chondrocytic differentiation. Int J Cancer (1998) 1.18
Red blood cell band 3. Lysine 539 and lysine 851 react with the same H2DIDS (4,4'-diisothiocyanodihydrostilbene-2,2'-disulfonic acid) molecule. J Biol Chem (1994) 1.18
Mitochondrial porin can be translocated across both endoplasmic reticulum and mitochondrial membranes. J Biochem (1992) 1.17
Vascular endothelial growth factor inhibits apoptotic death in hematopoietic cells after exposure to chemotherapeutic drugs by inducing MCL1 acting as an antiapoptotic factor. Cancer Res (1998) 1.17
Binding of mitochondrial precursor proteins to the cytoplasmic domains of the import receptors Tom70 and Tom20 is determined by cytoplasmic chaperones. EMBO J (1997) 1.17
Identification of early plasma cells in peripheral blood and their clinical significance. Br J Haematol (1996) 1.16
Assessment of topogenic functions of anticipated transmembrane segments of human band 3. J Biol Chem (1998) 1.15
Binding of human mitochondrial transcription factor A, an HMG box protein, to a four-way DNA junction. Biochem Biophys Res Commun (2000) 1.15
Glucocorticoid-induced diabetes mellitus: prevalence and risk factors in primary renal diseases. Nephron Clin Pract (2006) 1.15
Biased signalling and proteinase-activated receptors (PARs): targeting inflammatory disease. Br J Pharmacol (2014) 1.13
cDNA cloning and characterization of mitochondrial import stimulation factor (MSF) purified from rat liver cytosol. J Biochem (1994) 1.13
Vibration-induced hyperresponsiveness of arterial smooth muscle to noradrenaline with special reference to Raynaud's phenomenon in vibration disease. Cardiovasc Res (1978) 1.12
Membrane topogenesis of a type I signal-anchor protein, mouse synaptotagmin II, on the endoplasmic reticulum. J Cell Biol (2000) 1.12
Sensitivity to two major allergens (Cry j I and Cry j II) in patients with Japanese cedar (Cryptomeria japonica) pollinosis. Clin Exp Allergy (1995) 1.12
Cytoplasmic chaperones determine the targeting pathway of precursor proteins to mitochondria. EMBO J (1996) 1.11
Production of cytokines by peripheral blood monocytes/macrophages infected with human immunodeficiency virus type 1 (HIV-1). J Infect Dis (1990) 1.11
Antagonistic effects of an alternative splice variant of human IL-4, IL-4delta2, on IL-4 activities in human monocytes and B cells. Cell Immunol (1999) 1.10
Progression of coronary atherosclerosis: is coronary spasm related to progression? J Am Coll Cardiol (1991) 1.09
Expression of Polycomb-group (PcG) protein BMI-1 predicts prognosis in patients with acute myeloid leukemia. Leukemia (2007) 1.08
Adenovirus-mediated REIC/Dkk-3 gene transfer inhibits tumor growth and metastasis in an orthotopic prostate cancer model. Cancer Gene Ther (2007) 1.07
a4, a unique kidney-specific isoform of mouse vacuolar H+-ATPase subunit a. J Biol Chem (2001) 1.07
Splenectomy-reduced hepatic injury induced by ischemia/reperfusion in the rat. Liver (1996) 1.07
Effect of dietary eicosapentaenoic acid on azoxymethane-induced colon carcinogenesis in rats. Cancer Res (1988) 1.06
Carcinoma of the colon in children: report of a case and review of the literature. Jpn J Surg (1988) 1.06
Localization of the pyridoxal phosphate binding site at the COOH-terminal region of erythrocyte band 3 protein. J Biol Chem (1988) 1.06
Indications, complications, and short-term clinical outcome of percutaneous transvenous mitral commissurotomy. Circulation (1989) 1.06
Identification of the protein import components of the rat mitochondrial inner membrane, rTIM17, rTIM23, and rTIM44. J Biochem (1998) 1.05
Hakata antigen, a new member of the ficolin/opsonin p35 family, is a novel human lectin secreted into bronchus/alveolus and bile. J Histochem Cytochem (1999) 1.05