J M Egan

Author PubWeight™ 51.42‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Glucagon-like peptide-1 increases cAMP but fails to augment contraction in adult rat cardiac myocytes. Circ Res 2001 2.56
2 Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas. Diabetes 2000 2.50
3 Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats. Endocrinology 2000 1.81
4 The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women. Int J Obes (Lond) 2010 1.61
5 Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats. Endocrinology 2000 1.56
6 Events surrounding the early development of Euglena chloroplasts: cellular origins of chloroplast enzymes in euglena. J Gen Microbiol 1974 1.48
7 Modulation of CCAAT/enhancer-binding protein-alpha gene expression by metabolic signals in rodent adipocytes. Endocrinology 1999 1.39
8 Once daily injection of exendin-4 to diabetic mice achieves long-term beneficial effects on blood glucose concentrations. Diabetologia 1999 1.34
9 Glucagon-like peptide 1 and exendin-4 convert pancreatic AR42J cells into glucagon- and insulin-producing cells. Diabetes 1999 1.31
10 Glucagon-like peptide-1 can reverse the age-related decline in glucose tolerance in rats. J Clin Invest 1997 1.20
11 Glucagon-like peptide-1 causes pancreatic duodenal homeobox-1 protein translocation from the cytoplasm to the nucleus of pancreatic beta-cells by a cyclic adenosine monophosphate/protein kinase A-dependent mechanism. Endocrinology 2001 1.12
12 Evidence for a pathogenetic role of xanthine oxidase in the "stunned" myocardium. Am J Physiol 1987 1.11
13 Impaired insulin secretion and increased insulin sensitivity in familial maturity-onset diabetes of the young 4 (insulin promoter factor 1 gene). Diabetes 2000 1.09
14 GLP-1 action in L6 myotubes is via a receptor different from the pancreatic GLP-1 receptor. Am J Physiol 1998 1.08
15 Protective function of von Hippel-Lindau protein against impaired protein processing in renal carcinoma cells. Mol Cell Biol 1999 0.98
16 Studies on chloroplast development and replication in Euglena. II. Identification of two different deoxyribonucleases. Arch Biochem Biophys 1970 0.98
17 Glucagon-like peptide-1. Recent Prog Horm Res 2001 0.98
18 Glucagon-like peptide-1 regulates the beta cell transcription factor, PDX-1, in insulinoma cells. Endocrinology 1999 0.98
19 Insulinotropic hormone glucagon-like peptide-1-(7-37) appears not to augment insulin-mediated glucose uptake in young men during euglycemia. J Clin Endocrinol Metab 1998 0.96
20 Age-dependent reduction in insulin secretion and insulin mRNA in isolated islets from rats. Am J Physiol 1995 0.95
21 Glucagon-like peptide-1 affects gene transcription and messenger ribonucleic acid stability of components of the insulin secretory system in RIN 1046-38 cells. Endocrinology 1995 0.94
22 Insertion of an N-terminal 6-aminohexanoic acid after the 7 amino acid position of glucagon-like peptide-1 produces a long-acting hypoglycemic agent. Endocrinology 2001 0.92
23 Effect of aging and diabetes on the enteroinsular axis. J Gerontol A Biol Sci Med Sci 2001 0.89
24 Effect of glucagon-like peptide 1 on non-insulin-mediated glucose uptake in the elderly patient with diabetes. Diabetes Care 2001 0.87
25 Glucagon-like peptide-1 does not mediate amylase release from AR42J cells. J Cell Physiol 1999 0.87
26 Incretin hormones regulate glucose-dependent insulin secretion in RIN 1046-38 cells: mechanisms of action. Endocrinology 1994 0.87
27 Differential expression of reg-I and reg-II genes during aging in the normal mouse. J Gerontol A Biol Sci Med Sci 1996 0.86
28 Molecular investigation of age-related changes in mouse endocrine pancreas. J Gerontol A Biol Sci Med Sci 1996 0.86
29 Insulin release and insulin mRNA levels in rat islets of Langerhans cultured on extracellular matrix. Pancreas 1996 0.85
30 Continuous epidural anesthesia in abdominal vascular surgery. A review of 100 consecutive cases. Am J Surg 1980 0.85
31 Diltiazem treatment impairs hepatic drug oxidation: studies of antipyrine. Clin Pharmacol Ther 1986 0.84
32 Overexpression of glucagon-like peptide-1 receptor in an insulin-secreting cell line enhances glucose responsiveness. Mol Cell Endocrinol 1997 0.84
33 GIP regulates glucose transporters, hexokinases, and glucose-induced insulin secretion in RIN 1046-38 cells. Mol Cell Endocrinol 1996 0.84
34 Relationship of a dominant advanced glycation end product, serum carboxymethyl-lysine, and abnormal glucose metabolism in adults: the Baltimore Longitudinal Study of Aging. J Nutr Health Aging 2010 0.83
35 Expression of the regenerating gene in the pancreas of aging mice. Transplant Proc 1994 0.81
36 Substrate-selective inhibition by verapamil and diltiazem: differential disposition of antipyrine and theophylline in humans. J Pharmacol Exp Ther 1988 0.80
37 Regulation of glucose transporters and hexose uptake in 3T3-L1 adipocytes: glucagon-like peptide-1 and insulin interactions. J Mol Endocrinol 1997 0.80
38 Novel therapeutic strategies for the treatment of type 2 diabetes. Diabetes Metab Rev 1998 0.80
39 The effects of GLP-1 on insulin release in young and old rats in the fasting state and during an intravenous glucose tolerance test. J Gerontol A Biol Sci Med Sci 1997 0.79
40 The effect of propylene glycol on antipyrine clearance in humans. Clin Pharmacol Ther 1987 0.78
41 Glucagon-like peptide-1 (7-37) augments insulin-mediated glucose uptake in elderly patients with diabetes. J Gerontol A Biol Sci Med Sci 2001 0.78
42 Development and preliminary validation of a plate-based CB1/CB2 receptor functional assay. Anal Biochem 2013 0.78
43 Amyloid precursor protein requires the insulin signaling pathway for neurotrophic activity. Brain Res Mol Brain Res 1997 0.78
44 Regenerating (reg) and insulin genes are expressed in prepancreatic mouse embryos. J Mol Endocrinol 1996 0.78
45 Assignment of the human pancreatic regenerating (REG) gene to chromosome 2p12. Genomics 1994 0.77
46 SNAP-25 is phosphorylated by glucose and GLP-1 in RIN 1046-38 cells. Biochem Biophys Res Commun 1997 0.77
47 Differential expression of a novel seven transmembrane domain protein in epididymal fat from aged and diabetic mice. Endocrinology 1999 0.77
48 Sex-specific differences in progressive glucose intolerance and hip geometry: the Baltimore Longitudinal Study of Aging. Osteoporos Int 2015 0.76
49 Comparison in young and elderly patients of pharmacodynamics and disposition of labetalol in systemic hypertension. Am J Cardiol 1987 0.75
50 Hyperglycemia is associated with relatively lower lean body mass in older adults. J Nutr Health Aging 2014 0.75
51 Catching up the orthopods. BMJ 1988 0.75
52 The contrary position to the nonresective treatment for abdominal aortic aneurysm. J Vasc Surg 1985 0.75
53 Glucagon-like peptide-1 (7-37) augments insulin release in elderly patients with diabetes. Diabetes Care 2001 0.75
54 Characterization of cultured human nesidioblasts and their associated macromolecules: cross-reactivity with a cloned rat pancreatic beta-cell line. Pancreas 1992 0.75
55 Blunt trauma to the chest. Am Surg 1976 0.75
56 Effects of nifedipine on hepatic drug oxidation. Pharmacology 1988 0.75
57 Lorazepam analysis using liquid chromatography: improved sensitivity for single-dose pharmacokinetic studies. J Chromatogr 1986 0.75