Published in Cell on March 01, 1975
Analysis of chromosomal integration and deletions of yeast plasmids. Nucleic Acids Res (1977) 16.66
Construction, replication, and chromatin structure of TRP1 RI circle, a multiple-copy synthetic plasmid derived from Saccharomyces cerevisiae chromosomal DNA. Mol Cell Biol (1982) 2.85
The presence of a defective LEU2 gene on 2 mu DNA recombinant plasmids of Saccharomyces cerevisiae is responsible for curing and high copy number. J Bacteriol (1983) 2.55
Characterization of 2-mum DNA of Saccharomyces cerevisiae by restriction fragment analysis and integration in an Escherichia coli plasmid. Proc Natl Acad Sci U S A (1976) 2.47
Yeast gene CDC8 encodes thymidylate kinase and is complemented by herpes thymidine kinase gene TK. Proc Natl Acad Sci U S A (1984) 2.36
Isolation of a condensed, intracellular form of the 2-micrometer DNA plasmid of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1979) 1.81
Occurrence of crossed strand-exchange forms in yeast DNA during meiosis. Proc Natl Acad Sci U S A (1979) 1.78
Yeast 2-micrometer plasmid DNA replication in vitro: origin and direction. Proc Natl Acad Sci U S A (1981) 1.36
Properties of REP3: a cis-acting locus required for stable propagation of the Saccharomyces cerevisiae plasmid 2 microns circle. Mol Cell Biol (1985) 1.36
Replication in vitro of the 2-micrometer DNA plasmid of yeast. Proc Natl Acad Sci U S A (1979) 1.33
Yeast 2-microns plasmid DNA replication in vitro: purification of the CDC8 gene product by complementation assay. Proc Natl Acad Sci U S A (1983) 1.30
2-micrometers DNA-like plasmids in the osmophilic haploid yeast Saccharomyces rouxii. J Bacteriol (1982) 1.29
Functional analysis of the yeast plasmid partition locus STB. EMBO J (1986) 1.28
Association of the 2-micron DNA plasmid with yeast folded chromosomes. Proc Natl Acad Sci U S A (1980) 1.19
A stable plasmid carrying the yeast Leu2 gene and containing only yeast deoxyribonucleic acid. J Bacteriol (1980) 1.15
Sensitivity to the Yeast Plasmid 2mu DNA is conferred by the nuclear allele nibl. Mol Cell Biol (1982) 1.12
Deoxyribonucleic acid plasmids in yeasts. Microbiol Rev (1989) 1.09
Saccharomyces cerevisiae plasmid, Scp or 2 mum: intracellular distribution, stability and nucleosomal-like packaging. Nucleic Acids Res (1980) 1.00
Curing of the 2 mu DNA plasmid from Saccharomyces cerevisiae. J Bacteriol (1981) 0.95
Protein complexes from active replicative fractions associate in vitro with the replication origins of yeast 2-micrometers DNA plasmid. Proc Natl Acad Sci U S A (1982) 0.87
Reconstruction of the yeast 2 micron plasmid partitioning mechanism. Nucleic Acids Res (1988) 0.84
Killer double-stranded ribonucleic acid synthesis in cell division cycle mutants of Saccharomyces cerevisiae. J Bacteriol (1977) 0.77
Extrachromosomal elements cause a reduced division potential in nib 1 strains of Saccharomyces cerevisiae. Genetics (1989) 0.75
The 2-μm plasmid encoded protein Raf1 regulates both stability and copy number of the plasmid by blocking the formation of the Rep1-Rep2 repressor complex. Nucleic Acids Res (2017) 0.75
The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver. Biochem J (1967) 12.40
Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair. Nature (1993) 10.95
A simple cytochemical technique for demonstration of DNA in cells infected with mycoplasmas and viruses. Nature (1975) 6.70
The use of fluorescent DNA-binding agent for detecting and separating yeast mitochondrial DNA. Methods Cell Biol (1975) 6.58
Global mapping of meiotic recombination hotspots and coldspots in the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2000) 5.57
Unequal meiotic recombination within tandem arrays of yeast ribosomal DNA genes. Cell (1980) 5.48
Simple Mendelian inheritance of the reiterated ribosomal DNA of yeast. Proc Natl Acad Sci U S A (1977) 4.86
Instability of simple sequence DNA in Saccharomyces cerevisiae. Mol Cell Biol (1992) 4.46
Intrachromosomal gene conversion in yeast. Nature (1981) 4.27
TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene. Cell (1995) 4.20
Integration of DNA fragments by illegitimate recombination in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1991) 4.18
Characterization of two types of yeast ribosomal DNA genes. J Bacteriol (1978) 3.87
Intrachromosomal gene conversion and the maintenance of sequence homogeneity among repeated genes. Genetics (1982) 3.70
The timing of deoxyribonucleic acid synthesis in the cell cycle of Saccharomyces cerevisiae. J Cell Biol (1965) 3.65
Yeast ribosomal DNA genes are located on chromosome XII. Proc Natl Acad Sci U S A (1979) 3.54
Unusual DNA sequences associated with the ends of yeast chromosomes. Nature (1984) 3.54
Expansions and contractions of the genetic map relative to the physical map of yeast chromosome III. Mol Cell Biol (1988) 3.53
Microsatellite instability in yeast: dependence on the length of the microsatellite. Genetics (1997) 3.51
Microsatellite instability in yeast: dependence on repeat unit size and DNA mismatch repair genes. Mol Cell Biol (1997) 3.49
Activities of enzymes involved in acetoacetate utilization in adult mammalian tissues. Biochem J (1971) 3.48
Palindromic sequences in heteroduplex DNA inhibit mismatch repair in yeast. Nature (1989) 3.45
Complete gene map of the plastid-like DNA of the malaria parasite Plasmodium falciparum. J Mol Biol (1996) 3.41
Effect of mutations in genes affecting homologous recombination on restriction enzyme-mediated and illegitimate recombination in Saccharomyces cerevisiae. Mol Cell Biol (1994) 3.41
Chromosomal translocations generated by high-frequency meiotic recombination between repeated yeast genes. Genetics (1986) 3.37
Ketone-body utilization by adult and suckling rat brain in vivo. Biochem J (1971) 3.32
Saccharomyces cerevisiae RAD5-encoded DNA repair protein contains DNA helicase and zinc-binding sequence motifs and affects the stability of simple repetitive sequences in the genome. Mol Cell Biol (1992) 3.12
Severe hypoglycemia and hyperinsulinemia in falciparum malaria. N Engl J Med (1983) 3.07
Cell-cycle-specific repair of DNA double strand breaks in Saccharomyces cerevisiae. Radiat Res (1980) 3.07
Concentrations of free glucogenic amino acids in livers of rats subjected to various metabolic stresses. Biochem J (1967) 3.07
Activity and intracellular distribution of enzymes of ketone-body metabolism in rat liver. Biochem J (1968) 3.06
Identification of yeast mutants with altered telomere structure. Proc Natl Acad Sci U S A (1986) 3.05
Physiological roles of ketone bodies as substrates and signals in mammalian tissues. Physiol Rev (1980) 2.94
High-frequency meiotic gene conversion between repeated genes on nonhomologous chromosomes in yeast. Proc Natl Acad Sci U S A (1985) 2.93
The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae. Nucleic Acids Res (1996) 2.90
Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae. Mol Cell Biol (1999) 2.88
Sedimentation properties of yeast chromosomal DNA. Proc Natl Acad Sci U S A (1972) 2.82
Analysis of a gene conversion gradient at the HIS4 locus in Saccharomyces cerevisiae. Genetics (1992) 2.60
The timing of the S phase and other nuclear events in yeast meiosis. Exp Cell Res (1983) 2.54
Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase delta (pol3-t). Mol Cell Biol (1998) 2.51
Is there left-handed DNA at the ends of yeast chromosomes? Nature (1983) 2.49
Meiosis-specific double-strand DNA breaks at the HIS4 recombination hot spot in the yeast Saccharomyces cerevisiae: control in cis and trans. Mol Cell Biol (1995) 2.49
Activities of enzymes of ketone-body utilization in brain and other tissues of suckling rats. Biochem J (1971) 2.44
Destabilization of simple repetitive DNA sequences by transcription in yeast. Genetics (1996) 2.39
Allelic and ectopic recombination between Ty elements in yeast. Genetics (1988) 2.38
DNA-binding protein RAP1 stimulates meiotic recombination at the HIS4 locus in yeast. Proc Natl Acad Sci U S A (1991) 2.38
Physical lengths of meiotic and mitotic gene conversion tracts in Saccharomyces cerevisiae. Genetics (1988) 2.36
Comparison of glucose metabolism in the lactating mammary gland of the rat in vivo and in vitro. Effects of starvation, prolactin or insulin deficiency. Biochem J (1977) 2.36
Purification and properties of crystalline 3-hydroxybutyrate dehydrogenase from Rhodopseudomonas spheroides. Biochem J (1967) 2.31
Genetic control of chromosome length in yeast. Proc Natl Acad Sci U S A (1985) 2.30
Physical detection of heteroduplexes during meiotic recombination in the yeast Saccharomyces cerevisiae. Mol Cell Biol (1993) 2.30
Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1995) 2.29
Transcription factors are required for the meiotic recombination hotspot at the HIS4 locus in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1993) 2.27
Initial effect of injury on ketone bodies and other blood metabolites. Lancet (1975) 2.27
Repair of specific base pair mismatches formed during meiotic recombination in the yeast Saccharomyces cerevisiae. Mol Cell Biol (1991) 2.23
Most of the yeast genomic sequences are not essential for cell growth and division. Cell (1986) 2.14
A promoter deletion reduces the rate of mitotic, but not meiotic, recombination at the HIS4 locus in yeast. Curr Genet (1992) 2.13
The Tn3 beta-lactamase gene acts as a hotspot for meiotic recombination in yeast. Genetics (1991) 2.12
Transformation of Saccharomyces cerevisiae with nonhomologous DNA: illegitimate integration of transforming DNA into yeast chromosomes and in vivo ligation of transforming DNA to mitochondrial DNA sequences. Mol Cell Biol (1993) 2.12
Effects of ischaemia on metabolite concentrations in rat liver. Biochem J (1970) 2.07
Recombination between genes located on nonhomologous chromosomes in Saccharomyces cerevisiae. Genetics (1983) 2.06
Changes in the concentrations of hepatic metabolites on administration of dihydroxyacetone or glycerol to starved rats and their relationship to the control of ketogenesis. Biochem J (1969) 2.04
Repair of DNA loops involves DNA-mismatch and nucleotide-excision repair proteins. Nature (1997) 2.01
Isolation and analysis of recombinant DNA molecules containing yeast DNA. Gene (1978) 1.99
Size and structure of yeast chromosomal DNA. Proc Natl Acad Sci U S A (1973) 1.98
Genetic control of microsatellite stability. Mutat Res (1997) 1.93
Alterations in the rate of lipogenesis in vivo in maternal liver and adipose tissue on premature weaning of lactating rats: a possible regulatory role of prolactin. Biochem J (1979) 1.92
The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeast. Genetics (2000) 1.89
Hypoglycaemia in African children with severe malaria. Lancet (1987) 1.88
Effects of streptozotocin on carbohydrate and lipid metabolism in the rat. Endocrinology (1971) 1.86
Genetic evidence that the meiotic recombination hotspot at the HIS4 locus of Saccharomyces cerevisiae does not represent a site for a symmetrically processed double-strand break. Genetics (1993) 1.85
Recombination associated with replication of malarial mitochondrial DNA. EMBO J (1996) 1.84
Triplet repeats form secondary structures that escape DNA repair in yeast. Proc Natl Acad Sci U S A (1999) 1.83
Induction of the cytoplasmic petite mutation in Saccharomyces cerevisiae by the antibacterial antibiotics erythromycin and chloramphenicol. Mol Gen Genet (1971) 1.77
Lipogenesis in interscapular brown adipose tissue of virgin, pregnant and lactating rats. The effects of intragastric feeding. Biochem J (1980) 1.75
Analysis of the junction between ribosomal RNA genes and single-copy chromosomal sequences in the yeast Saccharomyces cerevisiae. Cell (1982) 1.75
Seven-base-pair inverted repeats in DNA form stable hairpins in vivo in Saccharomyces cerevisiae. Genetics (1991) 1.73
Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase. Proc Natl Acad Sci U S A (2000) 1.72
Meiotic mapping of yeast ribosomal deoxyribonucleic acid on chromosome XII. J Bacteriol (1979) 1.71
Measurements of excision repair tracts formed during meiotic recombination in Saccharomyces cerevisiae. Mol Cell Biol (1992) 1.69
Relationship between nuclease-hypersensitive sites and meiotic recombination hot spot activity at the HIS4 locus of Saccharomyces cerevisiae. Mol Cell Biol (1996) 1.68
Turnover rates of ketone bodies in normal, starved and alloxan-diabetic rats. Biochem J (1968) 1.66
Interactions of glucose, acetoacetate and insulin in mammary-gland slices of lactating rats. Biochem J (1975) 1.66
The synthesis of mitochondrial DNA during the cell cycle in the yeast Saccharomyces cerevisiae. Biochem Biophys Res Commun (1971) 1.64
Role of pyruvate dehydrogenase and insulin in the regulation of lipogenesis in the lactating mammary gland of the rat during the starved-refed transition. Biochem J (1981) 1.64
Have malaria parasites three genomes? Parasitol Today (1991) 1.61
Extrachromosomal DNA in the Apicomplexa. Microbiol Mol Biol Rev (1997) 1.60
Regulation of lactating-rat mammary-gland lipogenesis by insulin and glucagon in vivo. The role and site of action of insulin in the transition to the starved state. Biochem J (1984) 1.59
Effects of lactation of ketogenesis from oleate or butyrate in rat hepatocytes. Biochem J (1977) 1.59
Replication of yeast chromosomal DNA. Nature (1974) 1.59
Simple Mendelian inheritance of the repeating yeast ribosomal DNA genes. Cold Spring Harb Symp Quant Biol (1978) 1.57
Nuclear pore absence from areas of close association between nucleus and vacuole in synchronous yeast cultures. J Ultrastruct Res (1976) 1.55
Fiber autoradiography of replicating yeast DNA. Exp Cell Res (1975) 1.54
An alkaline sucrose gradient analysis of the mechanism of nuclear DNA synthesis in the yeast Saccharomyces cerevisiae. Mol Gen Genet (1978) 1.53
Measurements of substrate uptake by mammary gland of the rat. Biochem J (1972) 1.51
The relevance of the nuclear division cycle to radiosensitivity in yeast. Mol Gen Genet (1978) 1.50
Recombination of plasmids into the Saccharomyces cerevisiae chromosome is reduced by small amounts of sequence heterogeneity. Mol Cell Biol (1983) 1.49
Origins of blood acetate in the rat. Biochem J (1977) 1.48
Involvement of the checkpoint protein Mec1p in silencing of gene expression at telomeres in Saccharomyces cerevisiae. Mol Cell Biol (2000) 1.46