Published in Nucleic Acids Res on February 15, 1996
Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. EMBO J (1998) 5.79
Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance. Nucleic Acids Res (1996) 4.37
The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance. Mol Cell Biol (1999) 4.32
RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase. Genetics (1999) 3.55
Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break repair. EMBO J (1997) 3.29
DNA end resection: many nucleases make light work. DNA Repair (Amst) (2009) 3.28
Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends. Genes Dev (2003) 3.21
Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids. Nucleic Acids Res (1998) 3.11
EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants. Genes Dev (2002) 3.05
DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes. Proc Natl Acad Sci U S A (1999) 2.97
Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae. Mol Cell Biol (1999) 2.88
Limitations of silencing at native yeast telomeres. EMBO J (1999) 2.73
Exo1 roles for repair of DNA double-strand breaks and meiotic crossing over in Saccharomyces cerevisiae. Mol Biol Cell (2000) 2.44
Ku acts in a unique way at the mammalian telomere to prevent end joining. Genes Dev (2000) 2.38
Progressive cis-inhibition of telomerase upon telomere elongation. EMBO J (1999) 2.37
Ku is associated with the telomere in mammals. Proc Natl Acad Sci U S A (1999) 2.36
Biochemical evidence for Ku-independent backup pathways of NHEJ. Nucleic Acids Res (2003) 2.05
Saccharomyces cerevisiae LIF1: a function involved in DNA double-strand break repair related to mammalian XRCC4. EMBO J (1998) 2.03
DNA double-strand-break sensitivity, DNA replication, and cell cycle arrest phenotypes of Ku-deficient Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1997) 2.00
Sir proteins, Rif proteins, and Cdc13p bind Saccharomyces telomeres in vivo. Mol Cell Biol (1998) 2.00
Protection of telomeres by the Ku protein in fission yeast. Mol Biol Cell (2000) 1.94
Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2. EMBO J (2010) 1.92
The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeast. Genetics (2000) 1.89
The function of DNA polymerase alpha at telomeric G tails is important for telomere homeostasis. Mol Cell Biol (2000) 1.65
A 'higher order' of telomere regulation: telomere heterochromatin and telomeric RNAs. EMBO J (2009) 1.56
Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end. Genetics (2012) 1.56
Differential suppression of DNA repair deficiencies of Yeast rad50, mre11 and xrs2 mutants by EXO1 and TLC1 (the RNA component of telomerase). Genetics (2002) 1.51
A quantitative assay for telomere protection in Saccharomyces cerevisiae. Genetics (2002) 1.49
Cdc13 cooperates with the yeast Ku proteins and Stn1 to regulate telomerase recruitment. Mol Cell Biol (2000) 1.48
The yeast telomere length counting machinery is sensitive to sequences at the telomere-nontelomere junction. Mol Cell Biol (1999) 1.45
Cdc13 prevents telomere uncapping and Rad50-dependent homologous recombination. EMBO J (2001) 1.41
Dependence of the regulation of telomere length on the type of subtelomeric repeat in the yeast Saccharomyces cerevisiae. Genetics (1999) 1.40
mRNAs encoding telomerase components and regulators are controlled by UPF genes in Saccharomyces cerevisiae. Eukaryot Cell (2003) 1.40
DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse. Mol Cell Biol (2006) 1.39
Intrachromatid excision of telomeric DNA as a mechanism for telomere size control in Saccharomyces cerevisiae. Mol Cell Biol (2001) 1.38
Involvement of DNA end-binding protein Ku in Ty element retrotransposition. Mol Cell Biol (1999) 1.33
RAD50 function is essential for telomere maintenance in Arabidopsis. Proc Natl Acad Sci U S A (2001) 1.32
ELG1, a regulator of genome stability, has a role in telomere length regulation and in silencing. Proc Natl Acad Sci U S A (2004) 1.31
The Ku heterodimer performs separable activities at double-strand breaks and chromosome termini. Mol Cell Biol (2003) 1.28
Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions. EMBO J (1997) 1.28
Non-homologous end-joining proteins are required for Agrobacterium T-DNA integration. EMBO J (2001) 1.28
Regulation of telomere length by checkpoint genes in Schizosaccharomyces pombe. Mol Biol Cell (1998) 1.27
Analysis of variable (diversity) joining recombination in DNAdependent protein kinase (DNA-PK)-deficient mice reveals DNA-PK-independent pathways for both signal and coding joint formation. Proc Natl Acad Sci U S A (1998) 1.26
TLC1 RNA nucleo-cytoplasmic trafficking links telomerase biogenesis to its recruitment to telomeres. EMBO J (2008) 1.24
Severe developmental defects, hypersensitivity to DNA-damaging agents, and lengthened telomeres in Arabidopsis MRE11 mutants. Plant Cell (2002) 1.24
trt-1 is the Caenorhabditis elegans catalytic subunit of telomerase. PLoS Genet (2006) 1.23
Repair of endonuclease-induced double-strand breaks in Saccharomyces cerevisiae: essential role for genes associated with nonhomologous end-joining. Genetics (1999) 1.21
Requirement for end-joining and checkpoint functions, but not RAD52-mediated recombination, after EcoRI endonuclease cleavage of Saccharomyces cerevisiae DNA. Mol Cell Biol (1998) 1.21
DOT4 links silencing and cell growth in Saccharomyces cerevisiae. Mol Cell Biol (1999) 1.18
Ku-deficient yeast strains exhibit alternative states of silencing competence. EMBO Rep (2001) 1.16
The perichromosomal layer. Chromosoma (2005) 1.16
Maintenance of double-stranded telomeric repeats as the critical determinant for cell viability in yeast cells lacking Ku. Mol Cell Biol (2002) 1.14
The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time. EMBO J (2006) 1.14
The Arabidopsis AtLIG4 gene is required for the repair of DNA damage, but not for the integration of Agrobacterium T-DNA. Nucleic Acids Res (2003) 1.14
Identification of two human nuclear proteins that recognise the cytosine-rich strand of human telomeres in vitro. Nucleic Acids Res (2000) 1.12
Telomerase dependence of telomere lengthening in Ku80 mutant Arabidopsis. Plant Cell (2003) 1.11
Telomerase subunit overexpression suppresses telomere-specific checkpoint activation in the yeast yku80 mutant. EMBO Rep (2001) 1.10
Mutually exclusive binding of telomerase RNA and DNA by Ku alters telomerase recruitment model. Cell (2012) 1.08
Saccharomyces cerevisiae Dap1p, a novel DNA damage response protein related to the mammalian membrane-associated progesterone receptor. Eukaryot Cell (2003) 1.07
Telomere length regulation and transcriptional silencing in KU80-deficient Trypanosoma brucei. Nucleic Acids Res (2004) 1.04
Multiple roles for Saccharomyces cerevisiae histone H2A in telomere position effect, Spt phenotypes and double-strand-break repair. Genetics (2003) 1.04
Varying the number of telomere-bound proteins does not alter telomere length in tel1Delta cells. Proc Natl Acad Sci U S A (1999) 1.03
The Ku protein complex is involved in length regulation of Drosophila telomeres. Genetics (2005) 1.02
Histone H3 lysine 56 acetylation by Rtt109 is crucial for chromosome positioning. J Cell Biol (2008) 1.00
Telomeres, histone code, and DNA damage response. Cytogenet Genome Res (2009) 0.98
Sudden telomere lengthening triggers a Rad53-dependent checkpoint in Saccharomyces cerevisiae. Mol Biol Cell (2003) 0.96
The Ku-like protein from Saccharomyces cerevisiae is required in vitro for the assembly of a stable multiprotein complex at a eukaryotic origin of replication. Proc Natl Acad Sci U S A (1996) 0.96
An alternate form of Ku80 is required for DNA end-binding activity in mammalian mitochondria. Nucleic Acids Res (2000) 0.93
Fission yeast Rhp51 is required for the maintenance of telomere structure in the absence of the Ku heterodimer. Nucleic Acids Res (2003) 0.92
The Saccharomyces cerevisiae suppressor of choline sensitivity (SCS2) gene is a multicopy Suppressor of mec1 telomeric silencing defects. Genetics (2001) 0.92
Tetrahymena mutants with short telomeres. Genetics (1998) 0.91
Regulation of telomere length by an N-terminal region of the yeast telomerase reverse transcriptase. Mol Cell Biol (2005) 0.90
DNA repair and recombination functions in Arabidopsis telomere maintenance. Chromosome Res (2005) 0.88
New function of CDC13 in positive telomere length regulation. Mol Cell Biol (2001) 0.87
The 86-kD subunit of Ku autoantigen mediates homotypic and heterotypic adhesion of multiple myeloma cells. J Clin Invest (1998) 0.86
Repressive and non-repressive chromatin at native telomeres in Saccharomyces cerevisiae. Epigenetics Chromatin (2009) 0.86
Knockout of the DNA ligase IV homolog gene in the sphingoid base producing yeast Pichia ciferrii significantly increases gene targeting efficiency. Curr Genet (2009) 0.86
Yeast telomerase appears to frequently copy the entire template in vivo. Nucleic Acids Res (2001) 0.85
The association of yKu with subtelomeric core X sequences prevents recombination involving telomeric sequences. Genetics (2009) 0.85
Sequential loading of Saccharomyces cerevisiae Ku and Cdc13p to telomeres. J Biol Chem (2009) 0.82
Regulation of Ku-DNA association by Yku70 C-terminal tail and SUMO modification. J Biol Chem (2014) 0.82
Nature vs nurture: interplay between the genetic control of telomere length and environmental factors. Cell Cycle (2013) 0.81
Dynamic regulation of single-stranded telomeres in Saccharomyces cerevisiae. Genetics (2008) 0.81
At short telomeres Tel1 directs early replication and phosphorylates Rif1. PLoS Genet (2014) 0.78
Synthetic cytotoxicity: digenic interactions with TEL1/ATM mutations reveal sensitivity to low doses of camptothecin. Genetics (2014) 0.78
Depleting components of the THO complex causes increased telomere length by reducing the expression of the telomere-associated protein Rif1p. PLoS One (2012) 0.78
Genetic and physical interactions between Tel2 and the Med15 Mediator subunit in Saccharomyces cerevisiae. PLoS One (2012) 0.77
The principal role of Ku in telomere length maintenance is promotion of Est1 association with telomeres. Genetics (2014) 0.77
The Candida albicans Ku70 modulates telomere length and structure by regulating both telomerase and recombination. PLoS One (2011) 0.76
Mec1p associates with functionally compromised telomeres. Chromosoma (2012) 0.76
Alternative arrangements of telomeric recognition sites regulate the binding mode of the DNA-binding domain of yeast Rap1. Biophys Chem (2015) 0.75
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TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene. Cell (1995) 4.20
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