Published in Immunology on August 01, 2000
Global influenza seasonality: reconciling patterns across temperate and tropical regions. Environ Health Perspect (2010) 3.09
Anti-inflammatory properties of alpha- and gamma-tocopherol. Mol Aspects Med (2007) 1.31
Age-associated changes in immune and inflammatory responses: impact of vitamin E intervention. J Leukoc Biol (2008) 1.19
The role of nutrition in enhancing immunity in aging. Aging Dis (2011) 0.99
An aged host promotes the evolution of avirulent coxsackievirus into a virulent strain. Proc Natl Acad Sci U S A (2006) 0.91
Effect of age on susceptibility to Salmonella Typhimurium infection in C57BL/6 mice. J Med Microbiol (2009) 0.88
Effects of ageing on the immunoregulation of parasitic infection. Infect Immun (2002) 0.87
Prostaglandin E2-dependent IL-23 production in aged murine dendritic cells. Exp Gerontol (2010) 0.83
Genome-wide screening of alpha-tocopherol sensitive genes in heart tissue from alpha-tocopherol transfer protein null mice (ATTP(-/-)). FEBS Lett (2007) 0.82
Polymorphisms at cytokine genes may determine the effect of vitamin E on cytokine production in the elderly. J Nutr (2009) 0.79
Cytokine response to vitamin E supplementation is dependent on pre-supplementation cytokine levels. Biofactors (2008) 0.78
IL-2 and IL-10 gene polymorphisms are associated with respiratory tract infection and may modulate the effect of vitamin E on lower respiratory tract infections in elderly nursing home residents. Am J Clin Nutr (2010) 0.78
The immune response to herpes simplex virus encephalitis in mice is modulated by dietary vitamin E. J Nutr (2008) 0.77
Intracellular redox state as target for anti-influenza therapy: are antioxidants always effective? Curr Top Med Chem (2014) 0.77
Possible potentiation by certain antioxidants of the anti-inflammatory effects of diclofenac in rats. ScientificWorldJournal (2014) 0.75
Cellular responses to interferon-gamma. Annu Rev Immunol (1997) 13.23
Interleukin-6: an overview. Annu Rev Immunol (1990) 7.48
Trends in infectious diseases mortality in the United States. JAMA (1996) 5.79
Vitamin E supplementation and in vivo immune response in healthy elderly subjects. A randomized controlled trial. JAMA (1997) 3.68
Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines. J Immunol (1991) 3.66
Transgenic mice lacking class I major histocompatibility complex-restricted T cells have delayed viral clearance and increased mortality after influenza virus challenge. J Exp Med (1992) 3.63
Pretreatment of plastic Petri dishes with fetal calf serum. A simple method for macrophage isolation. J Immunol Methods (1979) 3.33
Prostaglandin-E2 is a potent inhibitor of human interleukin 12 production. J Exp Med (1995) 2.98
Mice can recover from pulmonary influenza virus infection in the absence of class I-restricted cytotoxic T cells. J Immunol (1992) 2.60
Patterns of cytokine gene expression by CD4+ T cells from young and old mice. J Immunol (1993) 2.56
Influenza virus-specific CD4+ T helper type 2 T lymphocytes do not promote recovery from experimental virus infection. J Exp Med (1994) 2.53
Protective CD4+ and CD8+ T cells against influenza virus induced by vaccination with nucleoprotein DNA. J Virol (1998) 1.82
Altered cytokine production in the elderly. Mech Ageing Dev (1998) 1.47
Influenza in senescent mice: impaired cytotoxic T-lymphocyte activity is correlated with prolonged infection. Immunology (1991) 1.44
Acceleration of influenza virus clearance by Th1 cells in the nasal site of mice immunized intranasally with adjuvant-combined recombinant nucleoprotein. J Immunol (1996) 1.37
Interleukin-4 causes delayed virus clearance in influenza virus-infected mice. J Virol (1996) 1.37
Prostaglandin E2 and dexamethasone inhibit IL-12 receptor expression and IL-12 responsiveness. J Immunol (1998) 1.26
The immune response of aged mice to influenza: diminished T-cell proliferation, interleukin 2 production and cytotoxicity. Cell Immunol (1983) 1.12
Age-associated increase in PGE2 synthesis and COX activity in murine macrophages is reversed by vitamin E. Am J Physiol (1998) 1.11
Pulmonary immune response of young and aged mice after influenza challenge. J Lab Clin Med (1995) 1.08
Macrophage prostaglandin production contributes to the age-associated decrease in T cell function which is reversed by the dietary antioxidant vitamin E. Mech Ageing Dev (1997) 1.02
Reversal of age-related deficient influenza virus-specific CTL responses and IFN-gamma production by monophosphoryl lipid A. Cell Immunol (1996) 0.98
Age-related decline of human interferon alpha and interferon gamma production. Blut (1984) 0.96
Influenza A virus replication is inhibited by tumor necrosis factor-alpha in vitro. Arch Virol (1994) 0.94
Prostaglandin E2 inhibits human T-cell proliferation after crosslinking of the CD3-Ti complex by directly affecting T cells at an early step of the activation process. Cell Immunol (1987) 0.93
Investigations of the lymphokine system in elderly individuals. Mech Ageing Dev (1993) 0.92
Vitamin E supplementation decreases lung virus titers in mice infected with influenza. J Infect Dis (1997) 0.92
Age differences in eicosanoid production of mouse splenocytes: effects on mitogen-induced T-cell proliferation. J Gerontol (1994) 0.90
Vitamin E supplementation suppresses prostaglandin E1(2) synthesis and enhances the immune response of aged mice. Mech Ageing Dev (1986) 0.89
Effect of zinc deficiency on prostaglandin synthesis in different organs of the rat. J Nutr (1982) 0.87
Cytokines and impaired CD8+ CTL activity among elderly persons and the enhancing effect of IL-12. Mech Ageing Dev (1997) 0.87
Influenza infection of beta 2-microglobulin-deficient (beta 2m-/-) mice reveals a loss of CD4+ T cell functions with aging. J Immunol (1997) 0.84
Decreased capacity of aged mice to produce interferon-gamma in Legionella pneumophila infection. Mech Ageing Dev (1995) 0.77
The sequence of the human genome. Science (2001) 101.55
The genome sequence of Drosophila melanogaster. Science (2000) 74.32
THE EFFECT OF COMBINATION WITH DIAZO COMPOUNDS ON THE IMMUNOLOGICAL REACTIVITY OF ANTIBODIES. J Exp Med (1936) 7.43
Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature (2001) 5.95
Effect of Gibberellin on Germination of Lettuce Seed. Science (1957) 5.27
Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol Cell (2001) 5.19
Localization of neuronal and glial glutamate transporters. Neuron (1994) 5.14
Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction. Science (2000) 4.61
Weight gain continues in the 1990s: 10-year trends in weight and overweight from the CARDIA study. Coronary Artery Risk Development in Young Adults. Am J Epidemiol (2000) 4.49
Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation. Nat Immunol (2001) 3.97
Genome of Geobacter sulfurreducens: metal reduction in subsurface environments. Science (2003) 3.68
CD4-Induced conformational changes in the human immunodeficiency virus type 1 gp120 glycoprotein: consequences for virus entry and neutralization. J Virol (1998) 3.60
Relaxation of a single DNA molecule observed by optical microscopy. Science (1994) 3.58
Stretching of a single tethered polymer in a uniform flow. Science (1995) 3.48
Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1. EMBO J (1999) 3.18
Arrhythmias documented by 24 hour continuous electrocardiographic monitoring in 50 male medical students without apparent heart disease. Am J Cardiol (1977) 2.99
Prognostic significance of anaplastic lymphoma kinase (ALK) protein expression in adults with anaplastic large cell lymphoma. Blood (1999) 2.95
Single polymer dynamics in an elongational flow. Science (1997) 2.92
Cardiac T2* magnetic resonance for prediction of cardiac complications in thalassemia major. Circulation (2009) 2.85
Support vector machines for spam categorization. IEEE Trans Neural Netw (1999) 2.83
Superconductivity at 41 K and its competition with spin-density-wave instability in layered CeO1-xFxFeAs. Phys Rev Lett (2008) 2.72
Dishevelled proteins lead to two signaling pathways. Regulation of LEF-1 and c-Jun N-terminal kinase in mammalian cells. J Biol Chem (1999) 2.67
Direct observation of tube-like motion of a single polymer chain. Science (1994) 2.60
A new nomenclature for IL-1-family genes. Trends Immunol (2001) 2.57
Cysteine Protection against X Irradiation. Science (1949) 2.52
Subunits beta gamma of heterotrimeric G protein activate beta 2 isoform of phospholipase C. Nature (1992) 2.47
The association of pre-operative STOP-BANG scores with postoperative critical care admission. Anaesthesia (2013) 2.39
Hydrogen mapping of the lunar south pole using the LRO neutron detector experiment LEND. Science (2010) 2.38
Characterization of monoclonal antibody to DNA.RNA and its application to immunodetection of hybrids. J Immunol Methods (1986) 2.31
Dissection of functional domains of the pituitary-specific transcription factor GHF-1. Nature (1990) 2.23
Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Nature (2000) 2.17
Gamma-hydroxybutyrate: an emerging drug of abuse that causes physical dependence. Addiction (1997) 2.12
Retinoid signaling and activator protein-1 expression in ferrets given beta-carotene supplements and exposed to tobacco smoke. J Natl Cancer Inst (1999) 2.11
alpha-Latrotoxin stimulates exocytosis by the interaction with a neuronal G-protein-coupled receptor. Neuron (1997) 2.08
Crystalloid vs. colloid resuscitation: is one better? A randomized clinical study. Surgery (1979) 2.06
Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation. Proc Natl Acad Sci U S A (1998) 2.04
Seven-year trends in body weight and associations with lifestyle and behavioral characteristics in black and white young adults: the CARDIA study. Am J Public Health (1997) 2.01
Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development. Development (1992) 1.99
Human fibronectin binding to staphylococcal surface protein and its relative inefficiency in promoting phagocytosis by human polymorphonuclear leukocytes, monocytes, and alveolar macrophages. Infect Immun (1981) 1.97
Pharmacological profile of BIBN4096BS, the first selective small molecule CGRP antagonist. Br J Pharmacol (2000) 1.95
An ethics core curriculum for Australasian medical Schools. Med J Aust (2001) 1.95
Brain drug delivery of small molecules using immunoliposomes. Proc Natl Acad Sci U S A (1996) 1.91
Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras. J Biol Chem (2000) 1.88
Is Clostridium difficile endemic in chronic-care facilities? Lancet (1986) 1.88
Demonstration of dual A-V nodal pathways in patients with paroxysmal supraventricular tachycardia. Circulation (1973) 1.87
Structural basis of the recognition of the dishevelled DEP domain in the Wnt signaling pathway. Nat Struct Biol (2000) 1.85
Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Nature (2000) 1.85
Hematologic abnormalities in the acquired immune deficiency syndrome. Am J Med (1984) 1.85
Physiological transport forces govern drug distribution for stent-based delivery. Circulation (2001) 1.83
Reproductive potential predicts longevity of female Mediterranean fruitflies. Proc Biol Sci (2001) 1.78
Dawn at Vesta: testing the protoplanetary paradigm. Science (2012) 1.76
Tick anticoagulant peptide (TAP) is a novel inhibitor of blood coagulation factor Xa. Science (1990) 1.75
The effects of cycle length on cardiac refractory periods in man. Circulation (1974) 1.73
The Calyptogena magnifica chemoautotrophic symbiont genome. Science (2007) 1.73
Internal structure and early thermal evolution of Mars from Mars Global Surveyor topography and gravity. Science (2000) 1.71
Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells. J Exp Med (1999) 1.71
Clinical, electrocardiographic and electrophysiologic observations in patients with paroxysmal supraventricular tachycardia. Am J Cardiol (1978) 1.70
Renal transplantation using belatacept without maintenance steroids or calcineurin inhibitors. Am J Transplant (2014) 1.70
Tunneling electroresistance effect in ferroelectric tunnel junctions at the nanoscale. Nano Lett (2009) 1.69
Population pharmacokinetics of fluconazole in young infants. Antimicrob Agents Chemother (2008) 1.68
Lactococcus garvieae infections in humans: possible association with aquaculture outbreaks. Int J Clin Pract (2006) 1.67
Inhibition of the visual cycle in vivo by 13-cis retinoic acid protects from light damage and provides a mechanism for night blindness in isotretinoin therapy. Proc Natl Acad Sci U S A (2001) 1.67
Alternative bioassays of kinship between loci. Am J Hum Genet (1988) 1.66
Immunologic effects of yogurt. Am J Clin Nutr (2000) 1.64
Steady-state pharmacokinetics of delavirdine in HIV-positive patients: effect on erythromycin breath test. Clin Pharmacol Ther (1997) 1.64
Suppression of glycogen synthase kinase activity is not sufficient for leukemia enhancer factor-1 activation. J Biol Chem (1999) 1.61
Ancient geodynamics and global-scale hydrology on Mars. Science (2001) 1.61
Interleukin-1-induced anorexia in the rat. Influence of prostaglandins. J Clin Invest (1989) 1.61
Localization of PEPT1 and PEPT2 proton-coupled oligopeptide transporter mRNA and protein in rat kidney. Am J Physiol (1999) 1.59
Drosophila nuclear lamin precursor Dm0 is translated from either of two developmentally regulated mRNA species apparently encoded by a single gene. J Cell Biol (1988) 1.59
Osteoarthritis-like changes and decreased mechanical function of articular cartilage in the joints of mice with the chondrodysplasia gene (cho). Arthritis Rheum (2003) 1.58
Effects of IL-12 on the generation of cytotoxic activity in human CD8+ T lymphocytes. J Immunol (1993) 1.53
Immunological identification of two sulfhydryl-containing fragments of human plasma fibronectin. J Biol Chem (1982) 1.52
Lymphogranuloma venereum. I. Comparison of the Frei test, complement fixation test, and isolation of the agent. J Infect Dis (1969) 1.52
Adjuvant arthritis as a model of inflammatory cachexia. Arthritis Rheum (1997) 1.51
Mutagenesis of specificity and toxicity regions of a Bacillus thuringiensis protoxin gene. J Bacteriol (1995) 1.49
Midgut-specific immune molecules are produced by the blood-sucking insect Stomoxys calcitrans. Proc Natl Acad Sci U S A (1997) 1.49
The management of flail chest. A comparison of ventilatory and nonventilatory treatment. Am J Surg (1976) 1.48
Members of the Gq alpha subunit gene family activate phospholipase C beta isozymes. J Biol Chem (1992) 1.48
Selective G protein coupling by C-C chemokine receptors. J Biol Chem (1996) 1.46
Nitrate-enhanced thallium 201 single-photon emission computed tomography imaging in hibernating myocardium. Am Heart J (1999) 1.45
CYP2E1-dependent toxicity and oxidative stress in HepG2 cells. Free Radic Biol Med (2001) 1.44
Regional analysis of divorce in China since 1980. Demography (2000) 1.44
Benzodiazepine dependence and withdrawal: identification and medical management. J Am Board Fam Pract (1992) 1.43
Roles of phospholipase C beta2 in chemoattractant-elicited responses. Proc Natl Acad Sci U S A (1997) 1.43
Radiofrequency ablation therapy in idiopathic left ventricular tachycardia with no obvious structural heart disease. Circulation (1994) 1.42
A reappraisal of appendicitis in the elderly. Am J Surg (1990) 1.41
String-plucking as a mechanism of chordal rupture during balloon mitral valvuloplasty using inoue balloon catheter. Catheter Cardiovasc Interv (1999) 1.39
Video-assisted thoracoscopic operation for interruption of patent ductus arteriosus in adults. Ann Thorac Surg (1997) 1.39
Genetic alteration of phospholipase C beta3 expression modulates behavioral and cellular responses to mu opioids. Proc Natl Acad Sci U S A (1999) 1.39
Low-lying quasiparticle states and hidden collective charge instabilities in parent cobaltate superconductors. Phys Rev Lett (2006) 1.38
Nutrition, infection, and morbidity in leukemia. Pediatr Hematol Oncol (1989) 1.38
Section of the cricopharyngeus muscle for dysphagia. Arch Surg (1968) 1.35
Influenza virus. Curr Protoc Immunol (2001) 1.35
Extrogen control of uterine glucose metabolism. An analysis based on the transport and phosphorylation of 2-deoxyglucose. J Biol Chem (1968) 1.34
Specific involvement of G proteins in regulation of serum response factor-mediated gene transcription by different receptors. J Biol Chem (1998) 1.34
Increase in fasting insulin and glucose over seven years with increasing weight and inactivity of young adults. The CARDIA Study. Coronary Artery Risk Development in Young Adults. Am J Epidemiol (1996) 1.34
Boundary element method-based cortical potential imaging of somatosensory evoked potentials using subjects' magnetic resonance images. Neuroimage (2002) 1.32
Superhydrophobic films from raspberry-like particles. Nano Lett (2005) 1.31