Published in Cancer Res on August 01, 1975
Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals. Proc Natl Acad Sci U S A (1975) 8.66
Progress report. Cancer of the pancreas. Gut (1977) 1.36
Acinar cell neoplasms of the exocrine pancreas. J Clin Pathol (1977) 1.19
Experimental evidence for the origin of ductal-type adenocarcinoma from the islets of Langerhans. Am J Pathol (1997) 1.12
Studies of pancreatic carcinogenesis in different animal models. Environ Health Perspect (1984) 1.09
Environmental factors and diseases of the pancreas. Environ Health Perspect (1977) 1.04
Origin of tubular complexes developing during induction of pancreatic adenocarcinoma by 7,12-dimethylbenz(a)anthracene. Am J Pathol (1978) 1.01
Minimal change chronic pancreatitis. Gut (1992) 1.01
Human pancreatic adenocarcinoma line Capan-1 in tissue culture and the nude mouse: morphologic, biologic, and biochemical characteristics. Am J Pathol (1982) 0.97
Cholecystokinin and pancreatic cancer: the chicken or the egg? Am J Physiol Gastrointest Liver Physiol (2013) 0.96
Histogenesis of pancreatic carcinogenesis in the hamster: ultrastructural evidence. Environ Health Perspect (1984) 0.95
Chemical synthesis of oligodeoxyribonucleotides containing N3- and O4-carboxymethylthymidine and their formation in DNA. Nucleic Acids Res (2008) 0.93
Enhancing effect of partial gastrectomy on pancreatic carcinogenesis. Br J Cancer (1992) 0.92
Treatment of nitrosamine-induced pancreatic tumors in hamsters with analogs of somatostatin and luteinizing hormone-releasing hormone. Proc Natl Acad Sci U S A (1987) 0.91
Synthesis and characterization of oligodeoxyribonucleotides containing a site-specifically incorporated N6-carboxymethyl-2'-deoxyadenosine or N4-carboxymethyl-2'-deoxycytidine. Nucleic Acids Res (2010) 0.91
An in vitro model of pancreatic carcinoma. Morphology and in vivo growth. Am J Pathol (1976) 0.90
Experimental animal models of pancreatic carcinogenesis for prevention studies and their relevance to human disease. Cancers (Basel) (2011) 0.84
An ultrastructural study of acinic cell carcinomas of the canine pancreas. Am J Pathol (1978) 0.84
Effects of dimethylnitrosamine on organ-cultured adult human pancreas. Am J Pathol (1981) 0.84
An in vitro model of pancreas carcinogenesis: two-stage MNU--TPA effect. Am J Pathol (1980) 0.83
Retinoic acid receptor alpha mediates growth inhibition by retinoids in rat pancreatic carcinoma DSL-6A/C1 cells. Br J Cancer (1998) 0.83
Transplantable acinar cell carcinoma of the rat pancreas. Am J Pathol (1979) 0.83
Challenges and advances in mouse modeling for human pancreatic tumorigenesis and metastasis. Cancer Metastasis Rev (2013) 0.82
Animal model of human disease. Carcinoma of the pancreas in azaserine-treated rats. Am J Pathol (1981) 0.81
A Synthetic Lethal Interaction between Glutathione Synthesis and Mitochondrial Reactive Oxygen Species Provides a Tumor-Specific Vulnerability Dependent on STAT3. Mol Cell Biol (2015) 0.80
Effects of dietary fatty acids on the early stages of neoplastic induction in the rat pancreas. Changes in fatty acid composition and development of atypical acinar cell nodules. Int J Exp Pathol (1991) 0.79
Oligonucleotide microarray identifies genes differentially expressed during tumorigenesis of DMBA-induced pancreatic cancer in rats. PLoS One (2013) 0.78
Effect of experimental pancreatic growth on the content of xenobiotic-metabolising enzymes in the pancreas. Gut (1987) 0.77
The growth pattern and microvasculature of pancreatic tumours induced with cultured carcinoma cells. Br J Cancer (2000) 0.76
Effects of N-nitrosobis(2-oxopropyl)amine in newborn and suckling hamsters. Br J Cancer (1980) 0.75
Pancreatic intraepithelial neoplasia: a new nomenclature and classification system for pancreatic duct lesions. Am J Surg Pathol (2001) 6.30
Acute hemorrhagic pancreatitis (massive necrosis) with fat necrosis induced in mice by DL-ethionine fed with a choline-deficient diet. Am J Pathol (1975) 2.23
K-ras mutations in pancreatic ductal proliferative lesions. Am J Pathol (1994) 1.73
Isolation and growth characteristics of continuous cell lines from small-cell carcinoma of the lung. Cancer (1980) 1.73
Role of the forensic pathologist in the medicolegal certification of modes of death. J Forensic Sci (1968) 1.69
Ductal metaplasia of human exocrine pancreas and its association with carcinoma. Cancer Res (1985) 1.57
Development of cancer chemopreventive agents: oltipraz as a paradigm. Chem Res Toxicol (1999) 1.52
Pancreatic carcinoma in azaserine-treated rats: induction, classification and dietary modulation of incidence. Cancer (1981) 1.47
Transplantation of azaserine-induced carcinomas of pancreas in rats. Cancer Lett (1979) 1.40
Pancreatic tumors with cystic dilatation of the ducts: intraductal papillary mucinous neoplasms and intraductal oncocytic papillary neoplasms. Semin Diagn Pathol (2000) 1.35
Chemoprotection by organosulfur inducers of phase 2 enzymes: dithiolethiones and dithiins. Drug Metabol Drug Interact (2000) 1.34
Formation of immunochemical advanced glycosylation end products precedes and correlates with early manifestations of renal and retinal disease in diabetes. Diabetes (1995) 1.25
The relation of islet amyloid to the clinical type of diabetes. Hum Pathol (1981) 1.22
Focal acinar cell dysplasia in human pancreas. Cancer (1980) 1.18
K-ras mutation in focal proliferative lesions of human pancreas. Cancer Epidemiol Biomarkers Prev (1998) 1.16
Deoxyribonuclease IIalpha is required during the phagocytic phase of apoptosis and its loss causes perinatal lethality. Cell Death Differ (2002) 1.15
Experimental carcinogenesis in the pancreas. Int Rev Exp Pathol (1984) 1.11
Increased collagen-linked pentosidine levels and advanced glycosylation end products in early diabetic nephropathy. J Clin Invest (1993) 1.10
Regulation of phase 2 enzyme induction by oltipraz and other dithiolethiones. Carcinogenesis (1994) 1.09
Promotion by unsaturated fat of azaserine-induced pancreatic carcinogenesis in the rat. Cancer Res (1981) 1.08
Dietary modulation of azaserine-induced pancreatic carcinogenesis in the rat. Cancer Res (1981) 1.08
Carcinogen-induced lesions in the rat pancreas: effects of varying levels of essential fatty acid. Cancer Res (1985) 1.05
Only wild-type c-Ki-ras codons 12, 13, and 61 in human pancreatic acinar cell carcinomas. Mol Carcinog (1994) 1.05
Environmental factors and diseases of the pancreas. Environ Health Perspect (1977) 1.04
Molecular pathology of in-vivo inhibition of protein synthesis. Electron microscopy of rat pancreatic acinar cells in puromycin-induced necrosis. Am J Pathol (1968) 1.02
Characterization of the ELSV transgenic mouse model of pancreatic carcinoma. Histologic type of large and small tumors. Am J Pathol (1992) 1.01
Role of the basic helix-loop-helix transcription factor p48 in the differentiation phenotype of exocrine pancreas cancer cells. Cell Growth Differ (2000) 1.00
Acute and chronic cisplatin nephropathy in rats. Lab Invest (1981) 0.99
Carboxyhemoglobin in relation to smoking. Natl Cancer Inst Monogr (1968) 0.97
Pathology and pathogenesis of diseases of the pancreas. Am J Pathol (1982) 0.96
Derivation of ductlike cell lines from a transplantable acinar cell carcinoma of the rat pancreas. Am J Pathol (1993) 0.96
AGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia. Oncogene (2012) 0.95
Acute pancreatic necrosis induced by puromycin. Lab Invest (1967) 0.95
Induction of pancreatic carcinomas in rats with N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine: histopathology. J Natl Cancer Inst (1985) 0.94
Experimental induction of pancreatic carcinomas in the hamster with N delta-(N-methyl-N-nitrosocarbamoyl)-L-ornithine. J Natl Cancer Inst (1983) 0.94
Inhibitory effects of estrogen and castration on the early stage of pancreatic carcinogenesis in Fischer rats treated with azaserine. Cancer Res (1989) 0.94
Relationship between glycemic control and collagen-linked advanced glycosylation end products in type I diabetes. Diabetes Care (1993) 0.93
Identification of 7-carboxymethylguanine in DNA from pancreatic acinar cells exposed to azaserine. Cancer Res (1982) 0.93
Protection against aflatoxin B1-induced hepatic toxicity as short-term screen of cancer chemopreventive dithiolethiones. Fundam Appl Toxicol (1996) 0.92
Effect of age on nodule induction by azaserine and DNA synthesis in rat pancreas. J Natl Cancer Inst (1977) 0.92
The biochemical pathology of ethionine-induced pancreatic damage: ethionine incorporation into proteins, and ATP levels in pancreas of rats. Arch Biochem Biophys (1968) 0.92
Vascular structure and microcirculation of experimental pancreatic carcinoma in rats. Eur J Surg (2000) 0.92
Inhibition of a transplantable pancreatic carcinoma by castration and estradiol administration in rats. Cancer Res (1989) 0.91
Potent inhibition of aflatoxin-induced hepatic tumorigenesis by the monofunctional enzyme inducer 1,2-dithiole-3-thione. Carcinogenesis (1992) 0.91
Size and number of nuclei differ in normal and neoplastic acinar cells from rat pancreas. Pancreas (1986) 0.90
Carcinogenesis in the pancreas. Arch Pathol Lab Med (1983) 0.90
Hyperplasia and tumors of the islets of Langerhans in mice bearing an elastase I-SV40 T-antigen fusion gene. Carcinogenesis (1990) 0.90
Species and rat strain variation in pancreatic nodule induction by azaserine. J Natl Cancer Inst (1977) 0.90
What is the true rate of K-ras mutation in carcinoma of the pancreas? Pancreas (1998) 0.88
Activation of c-Ki-ras not detectable in adenomas or adenocarcinomas arising in rat pancreas. Mol Carcinog (1990) 0.87
Overexpression of cholecystokinin receptors in azaserine-induced neoplasms of the rat pancreas. Cancer Res (1992) 0.87
Effect of bombesin and caerulein on early stages of carcinogenesis induced by azaserine in the rat pancreas. Cancer Res (1987) 0.86
Pathologic and biochemical effects of azaserine in inbred Wistar/Lewis rats and noninbred CD-1 mice. J Natl Cancer Inst (1980) 0.86
Hyperplastic nodules and adenomas of exocrine pancreas in azaserine-treated rats. J Natl Cancer Inst (1974) 0.85
Enhanced cytotoxicity of mitomycin C in human tumour cells with inducers of DT-diaphorase. Br J Cancer (1999) 0.85
Intraductal papillary-mucinous tumors of the pancreas. Arch Pathol Lab Med (1995) 0.84
Identification of dithiolethiones with better chemopreventive properties than oltipraz. Carcinogenesis (1998) 0.84
Induction of DT-diaphorase in cancer chemoprevention and chemotherapy. Oncol Res (1997) 0.84
Pancreatoblastoma in an older adult. Arch Pathol Lab Med (1995) 0.83
Oxidative and conjugative metabolism of xenobiotics by isolated rat and hamster acinar cells. Drug Metab Dispos (1984) 0.83
Stimulation of in vivo pancreatic growth in the rat is mediated specifically by way of cholecystokinin-A receptors. Gastroenterology (1994) 0.83
Prophylactic use of radioactive gold in the treatment of primary ovarian cancer. Am J Obstet Gynecol (1966) 0.83
Induction of DT-diaphorase by 1,2-dithiole-3-thiones in human tumour and normal cells and effect on anti-tumour activity of bioreductive agents. Br J Cancer (1998) 0.83
Recovery of pancreas from mild puromycin-induced injury. A histologic and ultrastructure study in rats. Arch Pathol (1975) 0.83
Inhibition by retinoids of the growth of azaserine-induced foci in the rat pancreas. J Natl Cancer Inst (1984) 0.82
Response of the Syrian golden hamster to a nitrosourea amino acid carcinogen. Cancer Lett (1979) 0.82
Characterization of a 4-month protocol for the quantitation of BOP-induced lesions in hamster pancreas and its application in studying the effect of dietary fat. Carcinogenesis (1987) 0.82
Pancreatic carcinomas of acinar and mixed acinar/ductal phenotypes in Ela-1-myc transgenic mice do not contain c-K-ras mutations. Am J Pathol (1994) 0.82
On the ethionine-induced inhibition of protein synthesis in male and female rats--lack of effect on intestinal mucosa. Biochim Biophys Acta (1968) 0.82
Mutated c-K-ras in small pancreatic adenocarcinomas. Pancreas (1994) 0.82
Adenomatous hyperplasia of the liver. Arch Pathol Lab Med (1979) 0.82
Multiple atypical acinar cell nodules of the pancreas. Hum Pathol (1980) 0.82
Duct-like morphogenesis of Longnecker pancreatic acinar carcinoma cells maintained in vitro on seminiferous tubular basement membranes. Cancer Res (1986) 0.82
Relationship of age to prevalence of focal acinar cell dysplasia in the human pancreas. J Natl Cancer Inst (1980) 0.81
Species dependent pancreatic islet toxicity produced by cyproheptadine: alterations in beta cell structure and function. Toxicol Appl Pharmacol (1971) 0.81
Animal model for small cell carcinoma of the lung. Effect of immunosuppression and sex of mouse on tumor growth in nude athymic mice. Exp Cell Biol (1980) 0.81
Animal model of human disease. Carcinoma of the pancreas in azaserine-treated rats. Am J Pathol (1981) 0.81
DNA damage and repair in rat tissues following administration of azaserine. Cancer Res (1977) 0.80
Carcinogenicity in rats of the nitrosourea amino acid N delta-(N-methyl-N-nitrosocarbamoyl)-L-ornithine. J Environ Pathol Toxicol (1980) 0.80
Evaluation of p53 mutation in pancreatic acinar cell carcinomas of humans and transgenic mice. Pancreas (1998) 0.80
The quest for preneoplastic lesions in the pancreas. Arch Pathol Lab Med (1994) 0.80
Induction of DT-diaphorase by 1,2-dithiole-3-thione and increase of antitumour activity of bioreductive agents. Br J Cancer Suppl (1996) 0.80
Azaserine-induced rat pancreas tumor model with transplantable cultured cells. Pancreas (1998) 0.79
Prospective and retrospective searches for liver necrosis following halothane anesthesia. Serum enzyme study and case report. JAMA (1966) 0.79
gamma-Glutamyltransferase activity in atypical acinar cell nodules of rat pancreas. Toxicol Appl Pharmacol (1987) 0.79
Inhibition of pancreatic and liver carcinogenesis in rats by retinoid- and selenium-supplemented diets. Pancreas (1988) 0.79
Evaluation of c-K-ras in pancreatic carcinomas from Ela-1, SV40E transgenic mice. Carcinogenesis (1993) 0.79
Enhancement of hepatocarcinogenesis in female rats by ethinyl estradiol and mestranol but not estradiol. Cancer Res (1984) 0.79
Marked differences in immunocytological localization of [3H]estradiol-binding protein in rat pancreatic acinar tumor cells compared to normal acinar cells. Endocrinology (1991) 0.79
Simultaneous mucinous cystadenoma of ovary and mucinous cystadenocarcinoma of pancreas. Int J Pancreatol (2000) 0.79
Cell lines derived from pancreatic tumors of Tg(Ela-1-SV40E)Bri18 transgenic mice express somatostatin and T antigen. Carcinogenesis (1994) 0.79
Mechanisms for the pancreatic oncogenic effects of the peroxisome proliferator Wyeth-14,643. Toxicol Appl Pharmacol (1997) 0.79