Published in Arch Biochem Biophys on September 20, 1968
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Acute hemorrhagic pancreatic necrosis in mice. Influence of the age and sex of the animals and of dietary ethionine, choline, methionine, and adenine sulfate. Am J Pathol (1975) 1.04
Influence of dietary factors on the pancreatotoxicity of ethionine. Am J Pathol (1976) 0.87
Pancreas acinar cell regeneration. IX. Effect of actinomycin D on microstructure. Am J Pathol (1971) 0.78
DL-ethionine treatment of adult pancreatic donors. Amelioration of diabetes in multiple recipients withe tissue from a single donor. Ann Surg (1979) 0.75
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Rapid emergence of carcinogen-induced hyperplastic lesions in a new model for the sequential analysis of liver carcinogenesis. Am J Pathol (1977) 2.45
The sequential analysis of cancer development. Adv Cancer Res (1980) 2.28
Acute hemorrhagic pancreatitis (massive necrosis) with fat necrosis induced in mice by DL-ethionine fed with a choline-deficient diet. Am J Pathol (1975) 2.23
Cell proliferation is not a major risk factor for cancer. Mod Pathol (1996) 2.05
The multistep nature of cancer development. Cancer Res (1984) 1.93
Adenocarcinoma of the pancreas in azaserine-treated rats. Cancer Res (1975) 1.83
Hepatocarcinogenesis: a dynamic cellular perspective. Lab Invest (1987) 1.82
K-ras mutations in pancreatic ductal proliferative lesions. Am J Pathol (1994) 1.73
Cellular biochemistry of the stepwise development of cancer with chemicals: G. H. A. Clowes memorial lecture. Cancer Res (1984) 1.70
The resistance of putative premalignant liver cell populations, hyperplastic nodules, to the acute cytotoxic effects of some hepatocarcinogens. Cancer Res (1976) 1.58
Ductal metaplasia of human exocrine pancreas and its association with carcinoma. Cancer Res (1985) 1.57
Studies on the proliferation and fate of oval cells in the liver of rats treated with 2-acetylaminofluorene and partial hepatectomy. Am J Pathol (1984) 1.48
Pancreatic carcinoma in azaserine-treated rats: induction, classification and dietary modulation of incidence. Cancer (1981) 1.47
The sequential analysis of liver cancer induction. Biochim Biophys Acta (1980) 1.46
Studies on DNA repair in human lymphocytes treated with proximate carcinogens and alkylating agents. Cancer Res (1971) 1.44
Induction of resistant hepatocytes as a new principle for a possible short-term in vivo test for carcinogens. Cancer Res (1980) 1.42
Chemical carcinogenesis. N Engl J Med (1981) 1.41
Transplantation of azaserine-induced carcinomas of pancreas in rats. Cancer Lett (1979) 1.40
Pancreatic tumors with cystic dilatation of the ducts: intraductal papillary mucinous neoplasms and intraductal oncocytic papillary neoplasms. Semin Diagn Pathol (2000) 1.35
Carcinogenesis--cellular evolution as a unifying thread: Presidential address. Cancer Res (1973) 1.30
The inhibition of liver ribonucleic acid synthesis by ethionine. J Biol Chem (1966) 1.30
Patterns of transfer RNA in normal rat liver and during hepatic carcinogenesis. Proc Natl Acad Sci U S A (1967) 1.27
Chemical carcinogenesis: a biologic perspective. Am J Pathol (1982) 1.26
A relative deficiency of cytochrome P-450 and aryl hydrocarbon [benzo(a)pyrene] hydroxylase in hyperplastic nodules induced by 2-acetylaminofluorene in rat liver. Cancer Res (1976) 1.26
Ethionine fatty liver. Adv Lipid Res (1967) 1.26
Initiation of chemical carcinogenesis requires cell proliferation. Nature (1978) 1.25
Gamma-glutamyltransferase in putative premalignant liver cell populations during hepatocarcinogenesis. Cancer Res (1978) 1.24
The relation of islet amyloid to the clinical type of diabetes. Hum Pathol (1981) 1.22
The rapid acceleration of hepatic nuclear ribonucleic acid breakdown by actinomycin but not by ethionine. J Biol Chem (1968) 1.21
Carcinogen-induced mdr overexpression is associated with xenobiotic resistance in rat preneoplastic liver nodules and hepatocellular carcinomas. Proc Natl Acad Sci U S A (1987) 1.21
Differences in growth of transplants of liver, liver hyperplastic nodules, and hepatocellular carcinomas in the mammary fat pad. Am J Pathol (1977) 1.20
On the mechanism of induction of hepatic adenosine triphosphate deficiency by ethionine. J Biol Chem (1966) 1.19
Reversal by adenine of the ethionine-induced lipid accumulation in the endoplasmic reticulum of the rat liver. A preliminary report. J Cell Biol (1965) 1.19
On the molecular pathology of ischemic renal cell death. Reversible and irreversible cellular and mitochondrial metabolic alterations. Am J Pathol (1968) 1.19
Focal acinar cell dysplasia in human pancreas. Cancer (1980) 1.18
Role of acute hepatic necrosis in the induction of early steps in liver carcinogenesis by diethylnitrosamine. Cancer Res (1981) 1.17
Cycloheximide, an inhibitor of peptide chain termination or release in liver in vivo and in vitro. Biochem Biophys Res Commun (1971) 1.17
Pre-cancerous steps in carcinogenesis. Their physiological adaptive nature. Biochim Biophys Acta (1984) 1.16
K-ras mutation in focal proliferative lesions of human pancreas. Cancer Epidemiol Biomarkers Prev (1998) 1.16
Biochemistry of carcinogenesis. Cancer Res (1968) 1.15
Deoxyribonuclease IIalpha is required during the phagocytic phase of apoptosis and its loss causes perinatal lethality. Cell Death Differ (2002) 1.15
Experimental carcinogenesis in the pancreas. Int Rev Exp Pathol (1984) 1.11
Intestinal metaplasia as a common option of oval cells in relation to cholangiofibrosis in liver of rats exposed to 2-acetylaminofluorene. Lab Invest (1985) 1.10
Promotion by unsaturated fat of azaserine-induced pancreatic carcinogenesis in the rat. Cancer Res (1981) 1.08
The induction of liver cancer by dietary deficiency of choline and methionine without added carcinogens. Carcinogenesis (1984) 1.08
Dietary modulation of azaserine-induced pancreatic carcinogenesis in the rat. Cancer Res (1981) 1.08
Phenotypic diversity as an early property of putative preneoplastic hepatocyte populations in liver carcinogenesis. Cancer Res (1980) 1.08
ATP and cell integrity. Fed Proc (1973) 1.07
Chemicals, evolution, and cancer development: Rous-Whipple Award Lecture. Am J Pathol (1982) 1.07
The biochemistry of preneoplastic liver: a common metabolic pattern in hepatocyte nodules. Can J Biochem Cell Biol (1984) 1.06
Nonrandom nature of in vivo methylation of dimethylnitrosamine and the subsequent removal of methylated products from rat liver chromatin DNA. Cancer Res (1976) 1.06
Effect of cycloheximide on the cell cycle of the crypts of the small intestine of the rat. J Cell Biol (1967) 1.06
Carcinogen-induced lesions in the rat pancreas: effects of varying levels of essential fatty acid. Cancer Res (1985) 1.05
Only wild-type c-Ki-ras codons 12, 13, and 61 in human pancreatic acinar cell carcinomas. Mol Carcinog (1994) 1.05
Newer insights into the pathogenesis of liver cancer. Am J Pathol (1977) 1.04
Environmental factors and diseases of the pancreas. Environ Health Perspect (1977) 1.04
Cellular analysis of liver carcinogenesis: the induction of large hyperplastic nodules in the liver with 2-fluorenylacetamide or ethionine and some aspects of their morphology and glycogen metabolism. Cancer Res (1967) 1.04
Hyperplastic areas, hyperplastic nodules, and hyperbasophilic areas as putative precursor lesions. Cancer Res (1976) 1.03
A common biochemical pattern in preneoplastic hepatocyte nodules generated in four different models in the rat. Cancer Res (1985) 1.02
Molecular pathology of in-vivo inhibition of protein synthesis. Electron microscopy of rat pancreatic acinar cells in puromycin-induced necrosis. Am J Pathol (1968) 1.02
Characterization of the ELSV transgenic mouse model of pancreatic carcinoma. Histologic type of large and small tumors. Am J Pathol (1992) 1.01
Role of the basic helix-loop-helix transcription factor p48 in the differentiation phenotype of exocrine pancreas cancer cells. Cell Growth Differ (2000) 1.00
Acute and chronic cisplatin nephropathy in rats. Lab Invest (1981) 0.99
Evidence for ethylation of rat liver deoxyribonucleic acid after administration of ethionine. Biochem J (1971) 0.98
The cancer-initiating potential of the fumonisin B mycotoxins. Carcinogenesis (1992) 0.97
Promotion of liver cancer development by brief exposure to dietary 2-acetylaminofluorene plus partial hepatectomy or carbon tetrachloride. Cancer Res (1983) 0.97
Biochemical pathology. Annu Rev Pharmacol (1971) 0.97
The biochemical pathology of inhibition of protein synthesis in vivo. The effects of cycloheximide on hepatic parenchymal cell ultrastructure. Lab Invest (1969) 0.97
Pathology and pathogenesis of diseases of the pancreas. Am J Pathol (1982) 0.96
Choline deficiency, lipotrope deficiency and the development of liver disease including liver cancer: a new perspective. Lab Invest (1993) 0.96
The disorganization of hepatic cell nucleoli induced by ethionine and its reversal by adenine. J Cell Biol (1968) 0.96
Derivation of ductlike cell lines from a transplantable acinar cell carcinoma of the rat pancreas. Am J Pathol (1993) 0.96
Kinetics of phenotypic maturation of remodeling of hyperplastic nodules during liver carcinogenesis. Cancer Res (1982) 0.96
AGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia. Oncogene (2012) 0.95
In vitro measurement of carcinogen-resistant liver cells during hepatocarcinogenesis. Int J Cancer (1978) 0.95
Acute pancreatic necrosis induced by puromycin. Lab Invest (1967) 0.95
The effect of cycloheximide on the interaction between mitochondrial respiration and gluconeogenesis in guinea pig and rat liver. J Biol Chem (1973) 0.95
Redifferentiation as a basis for remodeling of carcinogen-induced hepatocyte nodules to normal appearing liver. Cancer Res (1983) 0.95
Alternative methods of selecting rat hepatocellular nodules resistant to 2-acetylaminofluorene. Int J Cancer (1987) 0.95
Sequential analysis of hepatic carcinogenesis: a comparative study of the ultrastructure of preneoplastic, malignant, prenatal, postnatal, and regenerating liver. Lab Invest (1979) 0.94
Cell cycle kinetics of rat hepatocytes in early putative preneoplastic lesions in hepatocarcinogenesis. Cancer Res (1984) 0.94
Induction of pancreatic carcinomas in rats with N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine: histopathology. J Natl Cancer Inst (1985) 0.94
Inhibition of protein synthesis in rat liver by D-galactosamine. Res Commun Chem Pathol Pharmacol (1973) 0.94
Experimental induction of pancreatic carcinomas in the hamster with N delta-(N-methyl-N-nitrosocarbamoyl)-L-ornithine. J Natl Cancer Inst (1983) 0.94
Distinctive biochemical pattern associated with resistance of hepatocytes in hepatocyte nodules during liver carcinogenesis. Environ Health Perspect (1983) 0.94
Inhibitory effects of estrogen and castration on the early stage of pancreatic carcinogenesis in Fischer rats treated with azaserine. Cancer Res (1989) 0.94
Nature of early appearing, carcinogen-induced liver lesions to iron accumulation. J Natl Cancer Inst (1976) 0.93
Deoxyribonucleoside incorporation and the role of hydroxyurea in a model lymphocyte system for studying DNA repair in carcinogenesis. Cancer Res (1971) 0.93
Identification of 7-carboxymethylguanine in DNA from pancreatic acinar cells exposed to azaserine. Cancer Res (1982) 0.93
A probable role for protein synthesis in intestinal epithelial cell damage induced in vivo by cytosine arabinoside, nitrogen mustard, or X-irradiation. Cancer Res (1970) 0.93
Sequential alterations in growth control and cell dynamics of rat hepatocytes in early precancerous steps in hepatocarcinogenesis. Cancer Res (1986) 0.93
Vascular structure and microcirculation of experimental pancreatic carcinoma in rats. Eur J Surg (2000) 0.92
Effect of age on nodule induction by azaserine and DNA synthesis in rat pancreas. J Natl Cancer Inst (1977) 0.92
The binding of 2-acetylaminofluorene to rat liver ribonucleic acid in vivo. Cancer Res (1965) 0.92
Chordoma: a case report. Surg Neurol (1997) 0.91