Published in Nucleic Acids Res on November 28, 2008
High-throughput analysis of the mutagenic and cytotoxic properties of DNA lesions by next-generation sequencing. Nucleic Acids Res (2011) 1.43
Synthesis and characterization of oligodeoxyribonucleotides containing a site-specifically incorporated N6-carboxymethyl-2'-deoxyadenosine or N4-carboxymethyl-2'-deoxycytidine. Nucleic Acids Res (2010) 0.91
In vitro replication studies of carboxymethylated DNA lesions with Saccharomyces cerevisiae polymerase η. Biochemistry (2011) 0.90
Replication across regioisomeric ethylated thymidine lesions by purified DNA polymerases. Chem Res Toxicol (2013) 0.89
Transcriptional inhibition and mutagenesis induced by N-nitroso compound-derived carboxymethylated thymidine adducts in DNA. Nucleic Acids Res (2015) 0.86
Quantitative measurement of transcriptional inhibition and mutagenesis induced by site-specifically incorporated DNA lesions in vitro and in vivo. Nat Protoc (2015) 0.80
Roles of Aag, Alkbh2, and Alkbh3 in the Repair of Carboxymethylated and Ethylated Thymidine Lesions. ACS Chem Biol (2016) 0.75
Replication studies of carboxymethylated DNA lesions in human cells. Nucleic Acids Res (2017) 0.75
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Adenocarcinoma of the pancreas in azaserine-treated rats. Cancer Res (1975) 1.83
Assays for determining lesion bypass efficiency and mutagenicity of site-specific DNA lesions in vivo. Methods Enzymol (2006) 1.70
Efficient and accurate bypass of N2-(1-carboxyethyl)-2'-deoxyguanosine by DinB DNA polymerase in vitro and in vivo. Proc Natl Acad Sci U S A (2008) 1.70
Does increased endogenous formation of N-nitroso compounds in the human colon explain the association between red meat and colon cancer? Carcinogenesis (1996) 1.65
Endogenous versus exogenous exposure to N-nitroso compounds and gastric cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST) study. Carcinogenesis (2006) 1.43
Red meat enhances the colonic formation of the DNA adduct O6-carboxymethyl guanine: implications for colorectal cancer risk. Cancer Res (2006) 1.32
Nitrosated glycine derivatives as a potential source of O6-methylguanine in DNA. Cancer Res (1997) 1.07
Recognition and incision of oxidative intrastrand cross-link lesions by UvrABC nuclease. Biochemistry (2006) 1.07
A simple method for the solid phase synthesis of oligodeoxynucleotides containing O4-alkylthymine. Nucleic Acids Res (1990) 1.05
Carcinogenicity in rats of the nitrosated bile acid conjugates N-nitrosoglycocholic acid and N-nitrosotaurocholic acid. Cancer Res (1985) 1.00
Structure and fragmentation mechanisms of isomeric T-rich oligodeoxynucleotides: a comparison of four tandem mass spectrometric methods. J Am Soc Mass Spectrom (1998) 0.97
Potassium diazoacetate-induced p53 mutations in vitro in relation to formation of O6-carboxymethyl- and O6-methyl-2'-deoxyguanosine DNA adducts: relevance for gastrointestinal cancer. Carcinogenesis (2006) 0.96
Detection of concomitant formation of O6-carboxymethyl- and O6-methyl-2'-deoxyguanosine in DNA exposed to nitrosated glycine derivatives using a combined immunoaffinity/HPLC method. Chem Res Toxicol (1999) 0.94
Identification of 7-carboxymethylguanine in DNA from pancreatic acinar cells exposed to azaserine. Cancer Res (1982) 0.93
Detection of O6-carboxymethyl-2'-deoxyguanosine in DNA following reaction of nitric oxide with glycine and in human blood DNA using a quantitative immunoslot blot assay. Chem Res Toxicol (2004) 0.92
Synthesis, characterization, and immunochemical detection of O6-(carboxymethyl)-2'-deoxyguanosine: a DNA adduct formed by nitrosated glycine derivatives. Chem Res Toxicol (1997) 0.91
Synthesis and thermodynamic studies of oligodeoxyribonucleotides containing tandem lesions of thymidine glycol and 8-oxo-2'-deoxyguanosine. Chem Res Toxicol (2006) 0.89
The cytotoxicity of DNA carboxymethylation and methylation by the model carboxymethylating agent azaserine in human cells. Carcinogenesis (1999) 0.89
Mutagenicity of N-nitroso bile acid conjugates in Salmonella typhimurium and diploid human lymphoblasts. Cancer Res (1982) 0.86
The effect of potassium diazoacetate on human peripheral lymphocytes, human adenocarcinoma Colon caco-2 cells, and rat primary colon cells in the comet assay. Teratog Carcinog Mutagen (1999) 0.83
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity (2012) 5.08
Thirdhand tobacco smoke: emerging evidence and arguments for a multidisciplinary research agenda. Environ Health Perspect (2011) 3.69
5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations. Cancer Res (2011) 2.36
An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background. Nature (2012) 2.35
NF-κB inhibition delays DNA damage-induced senescence and aging in mice. J Clin Invest (2012) 1.91
Efficient and accurate bypass of N2-(1-carboxyethyl)-2'-deoxyguanosine by DinB DNA polymerase in vitro and in vivo. Proc Natl Acad Sci U S A (2008) 1.70
Statins activate AMP-activated protein kinase in vitro and in vivo. Circulation (2006) 1.55
Identification and quantification of a guanine-thymine intrastrand cross-link lesion induced by Cu(II)/H2O2/ascorbate. Chem Res Toxicol (2006) 1.52
Mass spectrometric analysis of high-mobility group proteins and their post-translational modifications in normal and cancerous human breast tissues. J Proteome Res (2007) 1.48
High-throughput analysis of the mutagenic and cytotoxic properties of DNA lesions by next-generation sequencing. Nucleic Acids Res (2011) 1.43
Formation and genotoxicity of a guanine-cytosine intrastrand cross-link lesion in vivo. Nucleic Acids Res (2007) 1.38
The DNA translocase FANCM/MHF promotes replication traverse of DNA interstrand crosslinks. Mol Cell (2013) 1.32
The oxidative DNA lesions 8,5'-cyclopurines accumulate with aging in a tissue-specific manner. Aging Cell (2012) 1.30
Independent generation of the 5-hydroxy-5,6-dihydrothymidin-6-yl radical and its reactivity in dinucleoside monophosphates. J Am Chem Soc (2004) 1.24
Independent generation of 5-(2'-deoxycytidinyl)methyl radical and the formation of a novel cross-link lesion between 5-methylcytosine and guanine. J Am Chem Soc (2003) 1.20
LC-MS/MS identification and yeast polymerase eta bypass of a novel gamma-irradiation-induced intrastrand cross-link lesion G[8-5]C. Biochemistry (2004) 1.18
Generation of 5-(2'-deoxycytidyl)methyl radical and the formation of intrastrand cross-link lesions in oligodeoxyribonucleotides. Nucleic Acids Res (2005) 1.17
On the formation and properties of interstrand DNA-DNA cross-links forged by reaction of an abasic site with the opposing guanine residue of 5'-CAp sequences in duplex DNA. J Am Chem Soc (2013) 1.17
Quantitative assessment of Tet-induced oxidation products of 5-methylcytosine in cellular and tissue DNA. Nucleic Acids Res (2013) 1.16
A quantitative assay for assessing the effects of DNA lesions on transcription. Nat Chem Biol (2012) 1.16
Tet-mediated formation of 5-hydroxymethylcytosine in RNA. J Am Chem Soc (2014) 1.14
In vivo formation and in vitro replication of a guanine-thymine intrastrand cross-link lesion. Biochemistry (2007) 1.13
Chronic epithelial NF-κB activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation. Proc Natl Acad Sci U S A (2012) 1.13
Redox reactions of copper complexes formed with different beta-amyloid peptides and their neuropathological [correction of neuropathalogical] relevance. Biochemistry (2007) 1.12
Formation of intrastrand cross-link products between cytosine and adenine from UV irradiation of d((Br)CA) and duplex DNA containing a 5-bromocytosine. J Am Chem Soc (2005) 1.11
Mutagenic and cytotoxic properties of 6-thioguanine, S6-methylthioguanine, and guanine-S6-sulfonic acid. J Biol Chem (2008) 1.11
Quantification of oxidative single-base and intrastrand cross-link lesions in unmethylated and CpG-methylated DNA induced by Fenton-type reagents. Nucleic Acids Res (2007) 1.10
The roles of DNA polymerases κ and ι in the error-free bypass of N2-carboxyalkyl-2'-deoxyguanosine lesions in mammalian cells. J Biol Chem (2011) 1.09
High mobility group proteins and their post-translational modifications. Biochim Biophys Acta (2008) 1.09
Recognition and incision of oxidative intrastrand cross-link lesions by UvrABC nuclease. Biochemistry (2006) 1.07
Interstrand DNA-DNA cross-link formation between adenine residues and abasic sites in duplex DNA. J Am Chem Soc (2014) 1.04
Efficient formation of the tandem thymine glycol/8-oxo-7,8-dihydroguanine lesion in isolated DNA and the mutagenic and cytotoxic properties of the tandem lesions in Escherichia coli cells. Chem Res Toxicol (2010) 1.04
Translesion synthesis of 8,5'-cyclopurine-2'-deoxynucleosides by DNA polymerases η, ι, and ζ. J Biol Chem (2013) 1.03
6-Thioguanine and S⁶-methylthioguanine are mutagenic in human cells. ACS Chem Biol (2010) 1.01
A targeted quantitative proteomics strategy for global kinome profiling of cancer cells and tissues. Mol Cell Proteomics (2014) 1.00
Thermodynamic and in vitro replication studies of an intrastrand G[8-5]C cross-link lesion. Biochemistry (2005) 1.00
Stereospecific synthesis and characterization of oligodeoxyribonucleotides containing an N2-(1-carboxyethyl)-2'-deoxyguanosine. J Am Chem Soc (2007) 0.98
Identification of novel α-n-methylation of CENP-B that regulates its binding to the centromeric DNA. J Proteome Res (2013) 0.98
Selective cavitand-mediated endocytosis of targeted imaging agents into live cells. J Am Chem Soc (2013) 0.97
LC-MS/MS for the detection of DNA interstrand cross-links formed by 8-methoxypsoralen and UVA irradiation in human cells. Anal Chem (2008) 0.97
A mass spectrometric study on the in vitro methylation of HMGA1a and HMGA1b proteins by PRMTs: methylation specificity, the effect of binding to AT-rich duplex DNA, and the effect of C-terminal phosphorylation. Biochemistry (2007) 0.97
Facile formation of an intrastrand cross-link lesion between cytosine and guanine upon pyrex-filtered UV light irradiation of d((Br)CG) and duplex DNA containing 5-bromocytosine. J Am Chem Soc (2004) 0.97
Quantitative analysis of DNA interstrand cross-links and monoadducts formed in human cells induced by psoralens and UVA irradiation. Anal Chem (2008) 0.97
Repair of mitomycin C mono- and interstrand cross-linked DNA adducts by UvrABC: a new model. Nucleic Acids Res (2010) 0.96
Mass spectrometric studies on epigenetic interaction networks in cell differentiation. J Biol Chem (2011) 0.96
Graphene as a novel matrix for the analysis of small molecules by MALDI-TOF MS. Anal Chem (2010) 0.96
The reactivity of the 5-hydroxy-5,6-dihydrothymidin-6-yl radical in oligodeoxyribonucleotides. Chem Res Toxicol (2005) 0.96
Ternary complexes of iron, amyloid-beta, and nitrilotriacetic acid: binding affinities, redox properties, and relevance to iron-induced oxidative stress in Alzheimer's disease. Biochemistry (2009) 0.96
Collisionally activated dissociation of protonated 2'-deoxycytidine, 2'-deoxyuridine, and their oxidatively damaged derivatives. J Am Soc Mass Spectrom (2006) 0.95
Derivatization with Girard reagent T combined with LC-MS/MS for the sensitive detection of 5-formyl-2'-deoxyuridine in cellular DNA. Anal Chem (2007) 0.95
Beta-elimination coupled with tandem mass spectrometry for the identification of in vivo and in vitro phosphorylation sites in maize dehydrin DHN1 protein. Biochemistry (2004) 0.95
5-Aza-2'-deoxycytidine induced growth inhibition of leukemia cells through modulating endogenous cholesterol biosynthesis. Mol Cell Proteomics (2012) 0.94
In vitro replication and repair studies of tandem lesions containing neighboring thymidine glycol and 8-oxo-7,8-dihydro-2'-deoxyguanosine. Chem Res Toxicol (2009) 0.94
Quantitative proteomic analysis reveals the perturbation of multiple cellular pathways in HL-60 cells induced by arsenite treatment. J Proteome Res (2010) 0.93
6-Thioguanine reactivates epigenetically silenced genes in acute lymphoblastic leukemia cells by facilitating proteasome-mediated degradation of DNMT1. Cancer Res (2011) 0.93
6-Thioguanine perturbs cytosine methylation at the CpG dinucleotide site by DNA methyltransferases in vitro and acts as a DNA demethylating agent in vivo. Biochemistry (2009) 0.93
JBP1 and JBP2 proteins are Fe2+/2-oxoglutarate-dependent dioxygenases regulating hydroxylation of thymidine residues in trypanosome DNA. J Biol Chem (2012) 0.93
In vitro replication and thermodynamic studies of methylation and oxidation modifications of 6-thioguanine. Nucleic Acids Res (2007) 0.93
Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation. PLoS One (2012) 0.93
Structure elucidation of DNA interstrand cross-link by a combination of nuclease P1 digestion with mass spectrometry. Anal Chem (2003) 0.92
Acetylation and phosphorylation of high-mobility group A1 proteins in PC-3 human tumor cells. Biochemistry (2006) 0.91
Further studies on the fragmentation of protonated ions of peptides containing aspartic acid, glutamic acid, cysteine sulfinic acid, and cysteine sulfonic acid. Rapid Commun Mass Spectrom (2005) 0.91
Methyl group migration during the fragmentation of singly charged ions of trimethyllysine-containing peptides: precaution of using MS/MS of singly charged ions for interrogating peptide methylation. J Am Soc Mass Spectrom (2009) 0.91
Endogenous formation and repair of oxidatively induced G[8-5 m]T intrastrand cross-link lesion. Nucleic Acids Res (2012) 0.91
Synthesis and characterization of oligodeoxyribonucleotides containing a site-specifically incorporated N6-carboxymethyl-2'-deoxyadenosine or N4-carboxymethyl-2'-deoxycytidine. Nucleic Acids Res (2010) 0.91
Probing adenosine nucleotide-binding proteins with an affinity-labeled nucleotide probe and mass spectrometry. Anal Chem (2007) 0.91
Proteome-wide discovery and characterizations of nucleotide-binding proteins with affinity-labeled chemical probes. Anal Chem (2013) 0.90
In-vitro replication studies on O(2)-methylthymidine and O(4)-methylthymidine. Chem Res Toxicol (2012) 0.90
Widespread existence of cytosine methylation in yeast DNA measured by gas chromatography/mass spectrometry. Anal Chem (2012) 0.90
Tandem mass spectrometry for the examination of the posttranslational modifications of high-mobility group A1 proteins: symmetric and asymmetric dimethylation of Arg25 in HMGA1a protein. Biochemistry (2005) 0.90
Identification and characterization of a novel cross-link lesion in d(CpC) upon 365-nm irradiation in the presence of 2-methyl-1,4-naphthoquinone. Nucleic Acids Res (2003) 0.90
In vitro replication studies of carboxymethylated DNA lesions with Saccharomyces cerevisiae polymerase η. Biochemistry (2011) 0.90
Replication across regioisomeric ethylated thymidine lesions by purified DNA polymerases. Chem Res Toxicol (2013) 0.89
LC-MS/MS coupled with stable isotope dilution method for the quantification of 6-thioguanine and S(6)-methylthioguanine in genomic DNA of human cancer cells treated with 6-thioguanine. Anal Chem (2010) 0.89
Synthesis and thermodynamic studies of oligodeoxyribonucleotides containing tandem lesions of thymidine glycol and 8-oxo-2'-deoxyguanosine. Chem Res Toxicol (2006) 0.89
Quantitative proteomic analysis revealed lovastatin-induced perturbation of cellular pathways in HL-60 cells. J Proteome Res (2011) 0.89
HMG modifications and nuclear function. Biochim Biophys Acta (2010) 0.88
Sequence-dependent formation of intrastrand crosslink products from the UVB irradiation of duplex DNA containing a 5-bromo-2'-deoxyuridine or 5-bromo-2'-deoxycytidine. Nucleic Acids Res (2006) 0.88
A quantitative study on the in vitro and in vivo acetylation of high mobility group A1 proteins. J Am Soc Mass Spectrom (2007) 0.88
Effects of 6-thioguanine and S6-methylthioguanine on transcription in vitro and in human cells. J Biol Chem (2012) 0.88
Ca2+/calmodulin-dependent protein kinase kinase β phosphorylation of Sirtuin 1 in endothelium is atheroprotective. Proc Natl Acad Sci U S A (2013) 0.88
Redox-dependent formation of disulfide bonds in human replication protein A. Rapid Commun Mass Spectrom (2007) 0.87
A method to determine the ionization efficiency change of peptides caused by phosphorylation. J Am Soc Mass Spectrom (2007) 0.86
Isotope-coded ATP probe for quantitative affinity profiling of ATP-binding proteins. Anal Chem (2013) 0.86
Isolation and characterization of a novel cross-link lesion in d(CpC) induced by one-electron photooxidation. Photochem Photobiol (2004) 0.86
Beta-arrestin inhibits CAMKKbeta-dependent AMPK activation downstream of protease-activated-receptor-2. BMC Biochem (2010) 0.86
Transcriptional inhibition and mutagenesis induced by N-nitroso compound-derived carboxymethylated thymidine adducts in DNA. Nucleic Acids Res (2015) 0.86
A density functional theory study on the kinetics and thermodynamics of N-glycosidic bond cleavage in 5-substituted 2'-deoxycytidines. Biochemistry (2012) 0.86
Site-selective modifications of arginine residues in human hemoglobin induced by methylglyoxal. Biochemistry (2006) 0.86
Quantitative analysis of surface plasma membrane proteins of primary and metastatic melanoma cells. J Proteome Res (2008) 0.85
Arsenite binds to the RING finger domains of RNF20-RNF40 histone E3 ubiquitin ligase and inhibits DNA double-strand break repair. J Am Chem Soc (2014) 0.85
Quantitative proteomic analysis reveals the perturbation of multiple cellular pathways in jurkat-T cells induced by doxorubicin. J Proteome Res (2010) 0.85
Exploring DNA-binding proteins with in vivo chemical cross-linking and mass spectrometry. J Proteome Res (2009) 0.85
Homeodomain-interacting protein kinase-2 (HIPK2) phosphorylates HMGA1a at Ser-35, Thr-52, and Thr-77 and modulates its DNA binding affinity. J Proteome Res (2007) 0.84
Mapping of lysine methylation and acetylation in core histones of Neurospora crassa. Biochemistry (2010) 0.84
The oxidation of yeast alcohol dehydrogenase-1 by hydrogen peroxide in vitro. J Proteome Res (2007) 0.84
6-thioguanine induces mitochondrial dysfunction and oxidative DNA damage in acute lymphoblastic leukemia cells. Mol Cell Proteomics (2013) 0.84