Published in Trends Genet on September 01, 2000
The PANTHER database of protein families, subfamilies, functions and pathways. Nucleic Acids Res (2005) 13.37
Large-scale gene function analysis with the PANTHER classification system. Nat Protoc (2013) 6.41
Applications for protein sequence-function evolution data: mRNA/protein expression analysis and coding SNP scoring tools. Nucleic Acids Res (2006) 5.02
Genomic islands of differentiation between house mouse subspecies. Genome Res (2006) 3.20
Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms. BMC Genomics (2006) 2.86
Potential role of miR-9 and miR-223 in recurrent ovarian cancer. Mol Cancer (2008) 2.53
Cell type-specific DNA methylation at intragenic CpG islands in the immune system. Genome Res (2011) 2.51
Transcriptome analysis of Crp-dependent catabolite control of gene expression in Escherichia coli. J Bacteriol (2004) 2.20
Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells. Cell Death Dis (2011) 1.51
The quantitative proteomes of human-induced pluripotent stem cells and embryonic stem cells. Mol Syst Biol (2011) 1.44
Gene expression patterns in the hippocampus and amygdala of endogenous depression and chronic stress models. Mol Psychiatry (2010) 1.28
Linking Notch signaling to ischemic stroke. Proc Natl Acad Sci U S A (2008) 1.28
Contrasting evolution of expression differences in the testis between species and subspecies of the house mouse. Genome Res (2006) 1.19
Transcriptome analysis describing new immunity and defense genes in peripheral blood mononuclear cells of rheumatoid arthritis patients. PLoS One (2009) 1.15
Identification of brain transcriptional variation reproduced in peripheral blood: an approach for mapping brain expression traits. Hum Mol Genet (2009) 1.15
Gene expression signature in peripheral blood detects thoracic aortic aneurysm. PLoS One (2007) 1.15
Performance comparison of two microarray platforms to assess differential gene expression in human monocyte and macrophage cells. BMC Genomics (2008) 1.14
Differential gene expression in a coculture model of angiogenesis reveals modulation of select pathways and a role for Notch signaling. Physiol Genomics (2008) 1.05
Comparative analysis of testis protein evolution in rodents. Genetics (2008) 1.02
The landscape of human genes involved in the immune response to parasitic worms. BMC Evol Biol (2010) 0.99
Genome-wide identification of susceptibility alleles for viral infections through a population genetics approach. PLoS Genet (2010) 0.94
Accumulation of stress and inducer-dependent plant-cell-wall-degrading enzymes during asexual development in Aspergillus nidulans. Genetics (2001) 0.93
Pharmacogenomics of 17-alpha hydroxyprogesterone caproate for recurrent preterm birth prevention. Am J Obstet Gynecol (2014) 0.91
PTRF/cavin-1 and MIF proteins are identified as non-small cell lung cancer biomarkers by label-free proteomics. PLoS One (2012) 0.91
Astrocyte-specific genes are generally demethylated in neural precursor cells prior to astrocytic differentiation. PLoS One (2008) 0.90
Genomic analysis of expressed sequence tags in American black bear Ursus americanus. BMC Genomics (2010) 0.89
Geographical mapping of a multifocal thyroid tumour using genetic alteration analysis & miRNA profiling. Mol Cancer (2008) 0.88
Development of a porcine (Sus scofa) embryo-specific microarray: array annotation and validation. BMC Genomics (2012) 0.87
Anti-proliferative action of vitamin D in MCF7 is still active after siRNA-VDR knock-down. BMC Genomics (2009) 0.87
Structure-based comparative analysis and prediction of N-linked glycosylation sites in evolutionarily distant eukaryotes. Genomics Proteomics Bioinformatics (2013) 0.86
The plasticizer butyl benzyl phthalate induces genomic changes in rat mammary gland after neonatal/prepubertal exposure. BMC Genomics (2007) 0.85
Role of aldo-keto reductases and other doxorubicin pharmacokinetic genes in doxorubicin resistance, DNA binding, and subcellular localization. BMC Cancer (2012) 0.85
Microarray analysis identifies a common set of cellular genes modulated by different HCV replicon clones. BMC Genomics (2008) 0.85
Comparison of transcriptional responses in liver tissue and primary hepatocyte cell cultures after exposure to hexahydro-1, 3, 5-trinitro-1, 3, 5-triazine. BMC Bioinformatics (2006) 0.83
Chemoresistance acquisition induces a global shift of expression of aniogenesis-associated genes and increased pro-angogenic activity in neuroblastoma cells. Mol Cancer (2009) 0.82
An integrated approach identifies IFN-regulated microRNAs and targeted mRNAs modulated by different HCV replicon clones. BMC Genomics (2011) 0.82
Mesenchymal Stem Cells Exhibit Regulated Exocytosis in Response to Chemerin and IGF. PLoS One (2015) 0.81
Novel polysome messages and changes in translational activity appear after induction of adipogenesis in 3T3-L1 cells. BMC Mol Biol (2012) 0.80
Lexical mediation of phonotactic frequency effects on spoken word recognition: A Granger causality analysis of MRI-constrained MEG/EEG data. J Mem Lang (2015) 0.80
Selection of a highly invasive neuroblastoma cell population through long-term human cytomegalovirus infection. Oncogenesis (2012) 0.80
How to Make a Dolphin: Molecular Signature of Positive Selection in Cetacean Genome. PLoS One (2013) 0.79
Prioritisation and network analysis of Crohn's disease susceptibility genes. PLoS One (2014) 0.78
Sentential influences on acoustic-phonetic processing: A Granger causality analysis of multimodal imaging data. Lang Cogn Neurosci (2015) 0.77
Gene variants associated with antisocial behaviour: a latent variable approach. J Child Psychol Psychiatry (2013) 0.77
The Evolution of Bony Vertebrate Enhancers at Odds with Their Coding Sequence Landscape. Genome Biol Evol (2015) 0.76
Nitric Oxide Mediated Transcriptome Profiling Reveals Activation of Multiple Regulatory Pathways in Arabidopsis thaliana. Front Plant Sci (2016) 0.76
Label-free LC-MS/MS shotgun proteomics to investigate the anti-inflammatory effect of rCC16. Mol Med Rep (2016) 0.75
The sequence of the human genome. Science (2001) 101.55
Systematic determination of genetic network architecture. Nat Genet (1999) 25.45
A genome-wide transcriptional analysis of the mitotic cell cycle. Mol Cell (1998) 19.67
Analysis of serial measurements in medical research. BMJ (1990) 16.69
Use of check lists in assessing the statistical content of medical studies. Br Med J (Clin Res Ed) (1986) 7.42
Transcriptional regulation and function during the human cell cycle. Nat Genet (2001) 5.89
Electrophysiological estimation of the number of motor units within a human muscle. J Neurol Neurosurg Psychiatry (1971) 4.70
Red blood cell magnesium and chronic fatigue syndrome. Lancet (1991) 4.48
Public knowledge of AIDS and the DHSS advertisement campaign. Br Med J (Clin Res Ed) (1986) 3.92
Laminar and regional distributions of neurofibrillary tangles and neuritic plaques in Alzheimer's disease: a quantitative study of visual and auditory cortices. J Neurosci (1987) 3.39
The relationship between upper respiratory infections and hospital admissions for asthma: a time-trend analysis. Am J Respir Crit Care Med (1996) 3.10
Physiological changes in ageing muscles. J Neurol Neurosurg Psychiatry (1973) 2.84
Induction of immune responses in patients with B-cell lymphoma against the surface-immunoglobulin idiotype expressed by their tumors. N Engl J Med (1992) 2.73
Randomised controlled trial of a short course of traditional acupuncture compared with usual care for persistent non-specific low back pain. BMJ (2006) 2.63
Recurrent brachial plexus neuropathy. Brain (1975) 2.63
Diabetes care from diagnosis: effects of training in patient-centred care on beliefs, attitudes and behaviour of primary care professionals. Patient Educ Couns (1999) 2.57
Can general practitioners influence exercise habits? Controlled trial. Br Med J (Clin Res Ed) (1985) 2.29
Electrophysiological study of dystrophia myotonica. J Neurol Neurosurg Psychiatry (1971) 2.20
Posture, blood velocity in common femoral vein, and prophylaxis of venous thromboembolism. Lancet (1995) 2.01
Assessment of the psychological impact of a breast screening programme. Br J Radiol (1991) 2.00
Twenty years' screening for cancer of the uterine cervix in Great Britain, 1964-84: further evidence for its ineffectiveness. J Epidemiol Community Health (1988) 1.91
"Sick" motoneurones. A unifying concept of muscle disease. Lancet (1971) 1.89
The development and validation of a clinical prediction model to determine the probability of MODY in patients with young-onset diabetes. Diabetologia (2012) 1.89
Clinical significance not statistical significance: a simple Bayesian alternative to p values. J Epidemiol Community Health (1998) 1.89
Mortality of men in the Rhondda Fach 1950-80. Br J Ind Med (1985) 1.70
Management of feverish children at home. BMJ (1992) 1.69
Intraclass correlation coefficient and outcome prevalence are associated in clustered binary data. J Clin Epidemiol (2005) 1.68
Randomized controlled trial of physiotherapy in 56 children with cerebral palsy followed for 18 months. Dev Med Child Neurol (2001) 1.66
Sudden infant death syndrome and environmental temperature: an analysis using vital statistics. J Epidemiol Community Health (1987) 1.60
Relationship between type of simple coalworkers' pneumoconiosis and lung function. A nine-year follow-up study of subjects with small rounded opacities. Br J Ind Med (1981) 1.58
Functional compensation in partially denervated muscles. J Neurol Neurosurg Psychiatry (1971) 1.57
Hospital outpatient clinics: an efficient specialist service? A neurology audit. J Neurol Neurosurg Psychiatry (1991) 1.53
Asthma at the interface: bridging the gap between general practice and a district general hospital. Arch Dis Child (1994) 1.51
How common is repeat sudden infant death syndrome? Arch Dis Child (2007) 1.51
Contamination in trials of educational interventions. Health Technol Assess (2007) 1.50
Effect of transdermal glyceryl trinitrate on the survival of peripheral intravenous infusions: a double-blind prospective clinical study. Br J Surg (1988) 1.49
Candidate regulatory sequence elements for cell cycle-dependent transcription in Saccharomyces cerevisiae. Genome Res (1999) 1.49
Two cases of cryptococcal meningitis, one treated with 5-fluorocytosine. Br Med J (1969) 1.43
Trials in primary care: statistical issues in the design, conduct and evaluation of complex interventions. Stat Methods Med Res (2010) 1.42
Mortality indicators used to rank hospital performance. BMJ (2013) 1.41
Trends in asthma mortality. Data on seasonality of deaths due to asthma were omitted from paper but editorial's author did not know. BMJ (1997) 1.41
Circaseptennial rhythm is an artefact. BMJ (1997) 1.40
Importance of antibody isotype in monoclonal anti-idiotype therapy of a murine B cell lymphoma. A study of hybridoma class switch variants. J Immunol (1986) 1.40
Trigeminal neuralgia and multiple sclerosis. A complex diagnosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (1995) 1.39
Orthopaedic geriatric care--is it effective? A prospective population-based comparison of outcome in fractured neck of femur. J R Coll Physicians Lond (1990) 1.38
A review of ordinal regression models applied on health-related quality of life assessments. Stat Methods Med Res (2002) 1.37
Public knowledge about AIDS increasing. Br Med J (Clin Res Ed) (1987) 1.35
Design and analysis of trials with quality of life as an outcome: a practical guide. J Biopharm Stat (2001) 1.33
The distribution of tyrosine hydroxylase-immunoreactive fibers in primate neocortex is widespread but regionally specific. J Neurosci (1987) 1.29
Assessing patient outcomes in acute exacerbations of chronic bronchitis: the measure your medical outcome profile (MYMOP), medical outcomes study 6-item general health survey (MOS-6A) and EuroQol (EQ-5D). Qual Life Res (2000) 1.28
Aetiological factors in rickets of prematurity. Arch Dis Child (1980) 1.25
Randomised controlled trial of breast shells and Hoffman's exercises for inverted and non-protractile nipples. BMJ (1992) 1.24
Computed tomography in the investigation of dementia. Br Med J (Clin Res Ed) (1983) 1.23
Irregular opacities in coalworkers' pneumoconiosis--correlation with pulmonary function and pathology. Ann Occup Hyg (1982) 1.23
Respiratory disability in ex-flax workers. Br J Ind Med (1986) 1.23
The Wessex Head Injury Matrix (WHIM) main scale: a preliminary report on a scale to assess and monitor patient recovery after severe head injury. Clin Rehabil (2000) 1.22
Neurological manifestations of xeroderma pigmentosum in two siblings. J Neurol Sci (1974) 1.20
The effect of postoperative nonsteroidal anti-inflammatory drug administration on spinal fusion. Spine (Phila Pa 1976) (1998) 1.19
Chest pain in women: a study of prevalence and mortality follow up in south Wales. J Epidemiol Community Health (1984) 1.19
Sample sizes for studies using the short form 36 (SF-36) J Epidemiol Community Health (1995) 1.17
Sequential immunological studies on an asbestos-exposed population. I. Factors affecting peripheral blood leucocytes and T lymphocytes. Clin Exp Immunol (1979) 1.16
Does dietary intake of vitamins C and E influence lung function in older people? Am J Respir Crit Care Med (1996) 1.15
Increased anti-influenza A virus cytotoxic T cell activity following vaccination of the chronically ill elderly with live attenuated or inactivated influenza virus vaccine. J Infect Dis (1995) 1.14
Management of motor neurone disease. J Neurol Sci (1984) 1.14
Myotubular, centronuclear or Peri-Centronuclear myopathy? J Neurol Sci (1969) 1.12
Combination of APACHE-II score and an obesity score (APACHE-O) for the prediction of severe acute pancreatitis. Pancreatology (2004) 1.12
Sequential immunological studies in an asbestos-exposed population. II. Factors affecting lymphocyte function. Clin Exp Immunol (1980) 1.11
The Wessex Recent In-Patient Suicide Study, 2. Case-control study of 59 in-patient suicides. Br J Psychiatry (2001) 1.10
Problems with the performance of the SF-36 among people with type 2 diabetes in general practice. Qual Life Res (2001) 1.09
Pathological findings in a case of hypothyroidism with ataxia. J Neurol Neurosurg Psychiatry (1971) 1.06
A monoclonal antibody to non-phosphorylated neurofilament protein marks the vulnerable cortical neurons in Alzheimer's disease. Brain Res (1987) 1.06
Tetracycline levels in bronchial secretions. J Clin Pathol (1970) 1.06
Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A. Oncogene (2001) 1.05
Functional immunoglobulin light chain genes are replaced by ongoing rearrangements of germline V kappa genes to downstream J kappa segment in a murine B cell line. J Exp Med (1989) 1.04
Evaluating the efficacy of acupuncture in defined aspects of stroke recovery: a randomised, placebo controlled single blind study. J Neurol (2008) 1.03
Double blind placebo controlled trial of nebulised budesonide for croup. Arch Dis Child (1997) 1.03
Comparison of audible sound transmission with ultrasound in screening for congenital dislocation of the hip. Lancet (1990) 1.02
An immunohistochemical characterization of somatostatin-28 and somatostatin-281-12 in monkey prefrontal cortex. J Comp Neurol (1986) 1.02
A comparison of primidone, propranolol, and placebo in essential tremor, using quantitative analysis. J Neurol Neurosurg Psychiatry (1986) 1.02
Substantial reductions in the number of diabetic ketoacidosis and severe hypoglycaemia episodes requiring emergency treatment lead to reduced costs after structured education in adults with Type 1 diabetes. Diabet Med (2014) 1.02
Alterations of the p15, p16,and p18 genes in osteosarcoma. Cancer Genet Cytogenet (1996) 1.01
Randomized, controlled trial of acetazolamide and furosemide in posthemorrhagic ventricular dilation in infancy: follow-up at 1 year. Pediatrics (2001) 1.01
Activation of the nickel-deficient carbon monoxide dehydrogenase from Rhodospirillum rubrum: kinetic characterization and reductant requirement. Biochemistry (1990) 1.01
The analysis using GENSTAT of anaemia, sugar intake and quetelet's index as prognostic indicators in women. Stat Med (1984) 1.00
The Wessex Recent In-Patient Suicide Study, 1. Case-control study of 234 recently discharged psychiatric patient suicides. Br J Psychiatry (2001) 1.00
Half-life of intracameral gentamicin after phacoemulsification. J Cataract Refract Surg (1997) 0.98
Distribution of choline acetyltransferase-, serotonin-, dopamine-beta-hydroxylase-, tyrosine hydroxylase-immunoreactive fibers in monkey primary auditory cortex. J Comp Neurol (1987) 0.97
Specific causes of death in miners and ex-miners of the Rhondda Fach 1950-80. Br J Ind Med (1986) 0.97
Ig VH gene expression among human follicular lymphomas. Blood (1991) 0.97
In vitro isoflavone supplementation reduces hydrogen peroxide-induced DNA damage in sperm. Teratog Carcinog Mutagen (2002) 0.96
Management of patients with motor neurone disease. Int Rehabil Med (1980) 0.96
Estimating sample sizes for continuous, binary, and ordinal outcomes in paired comparisons: practical hints. J Biopharm Stat (1999) 0.96
Predicting running speed from a simple questionnaire. Br J Sports Med (1985) 0.95
Transcription of the blk gene in human B lymphocytes is controlled by two promoters. J Biol Chem (1995) 0.94
Epidemiology of scabies prevalence in the U.K. from general practice records. Br J Dermatol (2011) 0.94
Hearing loss as a false localising sign in raised intracranial pressure. J Neurol Neurosurg Psychiatry (1995) 0.93