Published in PLoS One on September 11, 2008
CRNDE: A Long Non-Coding RNA Involved in CanceR, Neurobiology, and DEvelopment. Front Genet (2012) 1.45
Epigenetic silencing of miR-335 and its host gene MEST in hepatocellular carcinoma. Int J Oncol (2012) 1.04
DNA methylation functions as a critical regulator of Kir4.1 expression during CNS development. Glia (2014) 0.87
Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells. Cell (2016) 0.85
The emerging role of epigenetics in stroke: III. Neural stem cell biology and regenerative medicine. Arch Neurol (2011) 0.85
The Role of Astrocytes in Multiple Sclerosis Progression. Front Neurol (2015) 0.84
Epigenetic setting and reprogramming for neural cell fate determination and differentiation. Philos Trans R Soc Lond B Biol Sci (2014) 0.82
DNA methylation profile dynamics of tissue-dependent and differentially methylated regions during mouse brain development. BMC Genomics (2013) 0.80
Neural stem/progenitor cells derived from the embryonic dorsal telencephalon of D6/GFP mice differentiate primarily into neurons after transplantation into a cortical lesion. Cell Mol Neurobiol (2009) 0.79
Advancements in the Underlying Pathogenesis of Schizophrenia: Implications of DNA Methylation in Glial Cells. Front Cell Neurosci (2015) 0.77
CpG methylation differences between neurons and glia are highly conserved from mouse to human. Hum Mol Genet (2015) 0.77
Protein content and methyl donors in maternal diet interact to influence the proliferation rate and cell fate of neural stem cells in rat hippocampus. Nutrients (2014) 0.76
Human Stem Cell-Derived Astrocytes: Specification and Relevance for Neurological Disorders. Curr Stem Cell Rep (2016) 0.75
DNA methylation: an epigenetic mark of cellular memory. Exp Mol Med (2017) 0.75
Identification of genes associated with the astrocyte-specific gene Gfap during astrocyte differentiation. Sci Rep (2016) 0.75
Induced pluripotent stem cell lines derived from human somatic cells. Science (2007) 71.50
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature (2007) 65.18
A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell (2006) 48.80
DNA methylation patterns and epigenetic memory. Genes Dev (2002) 33.83
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell (1992) 27.80
Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet (2000) 21.52
Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell (2003) 20.16
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell (2003) 17.72
A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function. J Neurosci (2008) 17.27
Histone methyltransferase activity of a Drosophila Polycomb group repressor complex. Cell (2002) 13.05
Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell (2002) 12.28
Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. Mol Cell (2008) 7.68
Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300. Science (1999) 4.69
Association of tissue-specific differentially methylated regions (TDMs) with differential gene expression. Proc Natl Acad Sci U S A (2005) 4.59
Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway. Science (1997) 4.26
Timing of CNS cell generation: a programmed sequence of neuron and glial cell production from isolated murine cortical stem cells. Neuron (2000) 3.99
DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain. Dev Cell (2001) 2.90
Transcription, genomes, function. Trends Genet (2000) 2.86
Epigenetic control of mouse Oct-4 gene expression in embryonic stem cells and trophoblast stem cells. J Biol Chem (2004) 2.63
Bone morphogenetic proteins promote astroglial lineage commitment by mammalian subventricular zone progenitor cells. Neuron (1996) 2.52
Epigenetic regulation of Nanog gene in embryonic stem and trophoblast stem cells. Genes Cells (2007) 2.51
Notch1 and Notch3 instructively restrict bFGF-responsive multipotent neural progenitor cells to an astroglial fate. Neuron (2001) 2.06
Multiple routes to astrocytic differentiation in the CNS. J Neurosci (1998) 1.97
Variations in DNA methylation during mouse cell differentiation in vivo and in vitro. Proc Natl Acad Sci U S A (1984) 1.59
Lack of the Kir4.1 channel subunit abolishes K+ buffering properties of astrocytes in the ventral respiratory group: impact on extracellular K+ regulation. J Neurophysiol (2005) 1.57
Genome-wide profiling of promoter methylation in human. Oncogene (2006) 1.55
Association between variation in the human KCNJ10 potassium ion channel gene and seizure susceptibility. Epilepsy Res (2004) 1.42
Cystathionine beta-synthase, a key enzyme for homocysteine metabolism, is preferentially expressed in the radial glia/astrocyte lineage of developing mouse CNS. FASEB J (2005) 1.36
Supportive evidence for an allelic association of the human KCNJ10 potassium channel gene with idiopathic generalized epilepsy. Epilepsy Res (2005) 1.10
Role of Kir4.1 channels in growth control of glia. Glia (2007) 1.09
Developmental stage dependent regulation of DNA methylation and chromatin modification in a immature astrocyte specific gene promoter. FEBS Lett (2004) 1.07
A microarray-based method for detecting methylated loci. J Hum Genet (2002) 1.07
Analysis of CpG islands of trophoblast giant cells by restriction landmark genomic scanning. Dev Genet (1998) 1.04
SC1: a marker for astrocytes in the adult rodent brain is upregulated during reactive astrocytosis. Brain Res (1996) 0.94
Genome-wide demethylation during neural differentiation of P19 embryonal carcinoma cells. J Hum Genet (2008) 0.93
Genomic sequences of aldolase C (Zebrin II) direct lacZ expression exclusively in non-neuronal cells of transgenic mice. Proc Natl Acad Sci U S A (1998) 0.88
Candidate gene analysis of SPARCL1 gene in patients with multiple sclerosis. Neurosci Lett (2007) 0.79
Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells. Proc Natl Acad Sci U S A (2004) 3.60
Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis. Nat Neurosci (2009) 3.47
Expression and function of orphan nuclear receptor TLX in adult neural stem cells. Nature (2004) 3.25
L1 retrotransposition in neurons is modulated by MeCP2. Nature (2010) 3.25
A small modulatory dsRNA specifies the fate of adult neural stem cells. Cell (2004) 2.95
Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus. Cell Stem Cell (2010) 2.75
Cell fusion-independent differentiation of neural stem cells to the endothelial lineage. Nature (2004) 2.54
Committed neuronal precursors confer astrocytic potential on residual neural precursor cells. Dev Cell (2009) 2.45
Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function. Proc Natl Acad Sci U S A (2003) 2.44
Development of functional human embryonic stem cell-derived neurons in mouse brain. Proc Natl Acad Sci U S A (2005) 2.21
Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells. Proc Natl Acad Sci U S A (2006) 2.10
The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells. Nat Genet (2007) 2.10
IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes. J Cell Biol (2004) 2.02
Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation. Stem Cells Dev (2006) 1.88
Treatment of spinal cord injury by transplantation of fetal neural precursor cells engineered to express BMP inhibitor. Exp Neurol (2004) 1.82
Epigenetic modulation of seizure-induced neurogenesis and cognitive decline. J Neurosci (2007) 1.77
Neurons derived from transplanted neural stem cells restore disrupted neuronal circuitry in a mouse model of spinal cord injury. J Clin Invest (2010) 1.62
Involvement of Oct3/4 in the enhancement of neuronal differentiation of ES cells in neurogenesis-inducing cultures. Development (2003) 1.62
Dicer is required for maintaining adult pancreas. PLoS One (2009) 1.59
One Argonaute family member, Eif2c2 (Ago2), is essential for development and appears not to be involved in DNA methylation. Genomics (2007) 1.56
Nuclear receptor TLX regulates cell cycle progression in neural stem cells of the developing brain. Mol Endocrinol (2007) 1.43
Potentiation of astrogliogenesis by STAT3-mediated activation of bone morphogenetic protein-Smad signaling in neural stem cells. Mol Cell Biol (2007) 1.41
Generation of an ICF syndrome model by efficient genome editing of human induced pluripotent stem cells using the CRISPR system. Int J Mol Sci (2013) 1.34
Treatment of a mouse model of spinal cord injury by transplantation of human induced pluripotent stem cell-derived long-term self-renewing neuroepithelial-like stem cells. Stem Cells (2012) 1.33
MeCP2-dependent repression of an imprinted miR-184 released by depolarization. Hum Mol Genet (2008) 1.29
Enhanced gene activation by Notch and BMP signaling cross-talk. Nucleic Acids Res (2003) 1.20
Mammalian twisted gastrulation is essential for skeleto-lymphogenesis. Mol Cell Biol (2003) 1.17
Maintenance of embryonic stem cell pluripotency by Nanog-mediated reversal of mesoderm specification. Nat Clin Pract Cardiovasc Med (2006) 1.15
Periventricular notch activation and asymmetric Ngn2 and Tbr2 expression in pair-generated neocortical daughter cells. Mol Cell Neurosci (2008) 1.14
Epigenetic mechanisms regulating fate specification of neural stem cells. Philos Trans R Soc Lond B Biol Sci (2008) 1.13
Epigenetic regulation in neural stem cell differentiation. Dev Growth Differ (2010) 1.10
Microarray analysis of promoter methylation in lung cancers. J Hum Genet (2006) 1.09
Developmental stage dependent regulation of DNA methylation and chromatin modification in a immature astrocyte specific gene promoter. FEBS Lett (2004) 1.07
A microarray-based method for detecting methylated loci. J Hum Genet (2002) 1.07
Epigenetic regulation of neural cell differentiation plasticity in the adult mammalian brain. Proc Natl Acad Sci U S A (2008) 1.06
BMP-induced REST regulates the establishment and maintenance of astrocytic identity. J Cell Biol (2010) 1.05
Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiation. Nat Commun (2012) 1.03
Bidirectional promoters are the major source of gene activation-associated non-coding RNAs in mammals. BMC Genomics (2014) 1.03
Insulin biosynthesis in neuronal progenitors derived from adult hippocampus and the olfactory bulb. EMBO Mol Med (2011) 1.00
Stage- and site-specific DNA demethylation during neural cell development from embryonic stem cells. J Neurochem (2005) 1.00
miR-29 represses the activities of DNA methyltransferases and DNA demethylases. Int J Mol Sci (2013) 1.00
Role of GLI2 in the growth of human osteosarcoma. J Pathol (2011) 0.99
Physical performance and soleus muscle fiber composition in wild-derived and laboratory inbred mouse strains. J Appl Physiol (1985) (2003) 0.99
Effect of a worksite-based intervention program on metabolic parameters in middle-aged male white-collar workers: a randomized controlled trial. Prev Med (2010) 0.99
Neuronal differentiation of neural precursor cells is promoted by the methyl-CpG-binding protein MeCP2. Exp Neurol (2009) 0.98
Astrocyte differentiation of neural precursor cells is enhanced by retinoic acid through a change in epigenetic modification. Stem Cells (2009) 0.97
Methyl-CpG binding proteins are involved in restricting differentiation plasticity in neurons. J Neurosci Res (2006) 0.94
Genome-wide demethylation during neural differentiation of P19 embryonal carcinoma cells. J Hum Genet (2008) 0.93
Loss of genomic imprinting in mouse parthenogenetic embryonic stem cells. Stem Cells (2007) 0.93
Conversion of mammalian Müller glial cells into a neuronal lineage by in vitro aggregate-culture. Biochem Biophys Res Commun (2006) 0.93
Genome-wide analysis of DNA methylation and expression of microRNAs in breast cancer cells. Int J Mol Sci (2012) 0.92
Bcl-XL/Bax proteins direct the fate of embryonic cortical precursor cells. Mol Cell Biol (2007) 0.92
Chromatin remodeling in neural stem cell differentiation. Curr Opin Neurobiol (2010) 0.91
Cardiotrophin-like cytokine induces astrocyte differentiation of fetal neuroepithelial cells via activation of STAT3. Cytokine (2002) 0.91
Neurochondrin negatively regulates CaMKII phosphorylation, and nervous system-specific gene disruption results in epileptic seizure. J Biol Chem (2005) 0.90
Cloning of cDNA encoding a regeneration-associated muscle protease whose expression is attenuated in cell lines derived from Duchenne muscular dystrophy patients. Am J Pathol (2004) 0.89
Epigenetic mechanisms in sequential differentiation of neural stem cells. Epigenetics (2009) 0.89
Oxygen levels epigenetically regulate fate switching of neural precursor cells via hypoxia-inducible factor 1α-notch signal interaction in the developing brain. Stem Cells (2012) 0.89
Mechanisms of astrocytogenesis in the mammalian brain. Curr Opin Neurobiol (2013) 0.88
The Role of gp130 in cerebral cortical development: in vivo functional analysis in a mouse exo utero system. J Neurosci (2002) 0.88
Foxa2 acts as a co-activator potentiating expression of the Nurr1-induced DA phenotype via epigenetic regulation. Development (2014) 0.87
The NRSE smRNA specifies the fate of adult hippocampal neural stem cells. Nucleic Acids Symp Ser (Oxf) (2005) 0.87
Epigenetic regulation of neural stem cell fate during corticogenesis. Int J Dev Neurosci (2013) 0.84
Chromatin accessibility at a STAT3 target site is altered prior to astrocyte differentiation. Cell Struct Funct (2013) 0.84
Neuropoietin induces neuroepithelial cells to differentiate into astrocytes via activation of STAT3. Cytokine (2006) 0.83
Requirement of gp130 signaling for the AGM hematopoiesis. Exp Hematol (2003) 0.83
Epigenetic differences between embryonic stem cells generated from blastocysts developed in vitro and in vivo. Cell Reprogram (2010) 0.82
Epigenetic regulation of adipocyte differentiation by a Rho guanine nucleotide exchange factor, WGEF. PLoS One (2009) 0.82
Embryonic stem cells: staying plastic on plastic. Nat Med (2004) 0.82
Bypassing antibiotic selection: positive screening of genetically modified cells with an antigen-dependent proliferation switch. Nucleic Acids Res (2003) 0.82
Interisland evolution of Trimeresurus flavoviridis venom phospholipase A(2) isozymes. J Mol Evol (2003) 0.81
Induction of superficial cortical layer neurons from mouse embryonic stem cells by valproic acid. Neurosci Res (2011) 0.81
Mechanisms of neural stem cell fate determination: extracellular cues and intracellular programs. Curr Stem Cell Res Ther (2006) 0.81
[11C]PK11195 PET imaging of spinal glial activation after nerve injury in rats. Neuroimage (2013) 0.79
MiR-184 regulates insulin secretion through repression of Slc25a22. PeerJ (2013) 0.79