Published in Antimicrob Agents Chemother on October 01, 2000
Versatility of aminoglycosides and prospects for their future. Clin Microbiol Rev (2003) 3.72
Vancomycin-resistant Staphylococcus aureus isolate from a patient in Pennsylvania. Antimicrob Agents Chemother (2004) 3.44
Aminoglycoside modifying enzymes. Drug Resist Updat (2010) 3.19
High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. Antimicrob Agents Chemother (2006) 1.77
Emergence of resistance among USA300 methicillin-resistant Staphylococcus aureus isolates causing invasive disease in the United States. Antimicrob Agents Chemother (2010) 1.70
Multiplex PCR for detection of aminoglycoside resistance genes in enterococci. Antimicrob Agents Chemother (2003) 1.51
Molecular characterization of gentamicin-resistant Enterococci in the United States: evidence of spread from animals to humans through food. J Clin Microbiol (2003) 1.43
The crystal structures of substrate and nucleotide complexes of Enterococcus faecium aminoglycoside-2''-phosphotransferase-IIa [APH(2'')-IIa] provide insights into substrate selectivity in the APH(2'') subfamily. J Bacteriol (2009) 1.27
Source of phosphate in the enzymic reaction as a point of distinction among aminoglycoside 2''-phosphotransferases. J Biol Chem (2009) 1.21
The human gut resistome. Philos Trans R Soc Lond B Biol Sci (2015) 1.10
Aminoglycoside resistance genes aph(2")-Ib and aac(6')-Im detected together in strains of both Escherichia coli and Enterococcus faecium. Antimicrob Agents Chemother (2001) 1.07
Crystal structure and kinetic mechanism of aminoglycoside phosphotransferase-2''-IVa. Protein Sci (2010) 1.07
Relationship between the level of acquired resistance to gentamicin and synergism with amoxicillin in Enterococcus faecalis. Antimicrob Agents Chemother (2005) 0.97
Nucleotide selectivity of antibiotic kinases. Antimicrob Agents Chemother (2010) 0.92
Acquired gentamicin resistance by permeability impairment in Enterococcus faecalis. Antimicrob Agents Chemother (2006) 0.90
Aquaculture can promote the presence and spread of antibiotic-resistant Enterococci in marine sediments. PLoS One (2013) 0.86
Prospects for circumventing aminoglycoside kinase mediated antibiotic resistance. Front Cell Infect Microbiol (2013) 0.85
Mutant APH(2'')-IIa enzymes with increased activity against amikacin and isepamicin. Antimicrob Agents Chemother (2010) 0.82
High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. Antimicrob Agents Chemother (2007) 0.82
Purification, crystallization and preliminary X-ray analysis of Enterococcus faecium aminoglycoside-2''-phosphotransferase-Ib [APH(2'')-Ib]. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.79
Bulky "gatekeeper" residue changes the cosubstrate specificity of aminoglycoside 2''-phosphotransferase IIa. Antimicrob Agents Chemother (2013) 0.79
Purification, crystallization and preliminary X-ray analysis of Enterococcus casseliflavus aminoglycoside-2''-phosphotransferase-IVa. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.79
Mutations in the aph(2")-Ic gene are responsible for increased levels of aminoglycoside resistance. Antimicrob Agents Chemother (2002) 0.77
Structure of the phosphotransferase domain of the bifunctional aminoglycoside-resistance enzyme AAC(6')-Ie-APH(2'')-Ia. Acta Crystallogr D Biol Crystallogr (2014) 0.77
Antimicrobial susceptibility and resistance mechanisms of methicillin resistant Staphylococcus aureus isolated from 12 Hospitals in Turkey. Ann Clin Microbiol Antimicrob (2014) 0.75
Characterization of aminoglycoside resistance and virulence genes among Enterococcus spp. isolated from a hospital in China. Int J Environ Res Public Health (2015) 0.75
Comparison of microscan broth microdilution, synergy quad plate agar dilution, and disk diffusion screening methods for detection of high-level aminoglycoside resistance in enterococcus species. J Clin Microbiol (2003) 0.75
Basic local alignment search tool. J Mol Biol (1990) 659.07
A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res (1984) 181.98
Identification of Enterococcus species isolated from human infections by a conventional test scheme. J Clin Microbiol (1989) 13.84
Mapping of Streptococcus faecalis plasmids pAD1 and pAD2 and studies relating to transposition of Tn917. J Bacteriol (1982) 7.03
Highly efficient protoplast transformation system for Streptococcus faecalis and a new Escherichia coli-S. faecalis shuttle vector. J Bacteriol (1986) 5.35
DNA hybridization and contour-clamped homogeneous electric field electrophoresis for identification of enterococci to the species level. J Clin Microbiol (1995) 2.69
High-level resistance to gentamicin in clinical isolates of Streptococcus (Enterococcus) faecium. Antimicrob Agents Chemother (1988) 2.59
The aacA-aphD gentamicin and kanamycin resistance determinant of Tn4001 from Staphylococcus aureus: expression and nucleotide sequence analysis. J Gen Microbiol (1987) 2.58
Diversity among multidrug-resistant enterococci. Emerg Infect Dis (1998) 1.83
A novel gentamicin resistance gene in Enterococcus. Antimicrob Agents Chemother (1997) 1.63
A new high-level gentamicin resistance gene, aph(2'')-Id, in Enterococcus spp. Antimicrob Agents Chemother (1998) 1.60
Amikacin resistance associated with a plasmid-borne aminoglycoside phosphotransferase in Escherichia coli. Antimicrob Agents Chemother (1979) 1.51
In-vitro activity of arbekacin alone and in combination with vancomycin against gentamicin- and methicillin-resistant Staphylococcus aureus. Diagn Microbiol Infect Dis (2000) 1.18
Enzymatic 2'-N-acetylation of arbekacin and antibiotic activity of its product. J Antibiot (Tokyo) (1996) 1.05
Structures of enzymatically modified products of arbekacin by methicillin-resistant. Staphylococcus aureus. J Antibiot (Tokyo) (1993) 0.94
In vitro susceptibility and molecular analysis of gentamicin-resistant enterococci. Diagn Microbiol Infect Dis (1998) 0.89
Supercoiled circular DNA-protein complex in Escherichia coli: purification and induced conversion to an opern circular DNA form. Proc Natl Acad Sci U S A (1969) 71.62
Nature of Col E 1 plasmid replication in Escherichia coli in the presence of the chloramphenicol. J Bacteriol (1972) 46.61
Properties of a supercoiled deoxyribonucleic acid-protein relaxation complex and strand specificity of the relaxation event. Biochemistry (1970) 26.22
Characterization of three plasmid deoxyribonucleic acid molecules in a strain of Streptococcus faecalis: identification of a plasmid determining erythromycin resistance. J Bacteriol (1974) 12.44
Evidence for a chromosome-borne resistance transposon (Tn916) in Streptococcus faecalis that is capable of "conjugal" transfer in the absence of a conjugative plasmid. J Bacteriol (1981) 11.15
Emergence of vancomycin resistance in Staphylococcus aureus. Glycopeptide-Intermediate Staphylococcus aureus Working Group. N Engl J Med (1999) 10.21
Circular DNA. Annu Rev Biochem (1971) 9.75
Induced cell aggregation and mating in Streptococcus faecalis: evidence for a bacterial sex pheromone. Proc Natl Acad Sci U S A (1978) 9.67
Effect of growth conditions on the formation of the relaxation complex of supercoiled ColE1 deoxyribonucleic acid and protein in Escherichia coli. J Bacteriol (1972) 9.50
Transmissible toxin (hemolysin) plasmid in Streptococcus faecalis and its mobilization of a noninfectious drug resistance plasmid. J Bacteriol (1975) 8.65
Plasmids, drug resistance, and gene transfer in the genus Streptococcus. Microbiol Rev (1981) 7.86
Plasmid transfer in Streptococcus faecalis: production of multiple sex pheromones by recipients. Plasmid (1979) 7.20
Mapping of Streptococcus faecalis plasmids pAD1 and pAD2 and studies relating to transposition of Tn917. J Bacteriol (1982) 7.03
Complete nucleotide sequence of macrolide-lincosamide-streptogramin B-resistance transposon Tn917 in Streptococcus faecalis. J Bacteriol (1985) 7.00
Regeneration of insertionally inactivated streptococcal DNA fragments after excision of transposon Tn916 in Escherichia coli: strategy for targeting and cloning of genes from gram-positive bacteria. J Bacteriol (1984) 6.82
Properties of erythromycin-inducible transposon Tn917 in Streptococcus faecalis. J Bacteriol (1980) 6.06
Nosocomial infection by gentamicin-resistant Streptococcus faecalis. An epidemiologic study. Ann Intern Med (1987) 5.74
A transposon in Streptococcus faecalis with fertility properties. Nature (1982) 5.65
Escherichia coli K-12 auxotrophs induced by insertion of the transposable element Tn5. Genetics (1979) 5.49
Highly efficient protoplast transformation system for Streptococcus faecalis and a new Escherichia coli-S. faecalis shuttle vector. J Bacteriol (1986) 5.35
Novel shuttle plasmid vehicles for Escherichia-Streptococcus transgeneric cloning. Gene (1983) 5.30
Plasmid-related transmissibility and multiple drug resistance in Streptococcus faecalis subsp. zymogenes strain DS16. Antimicrob Agents Chemother (1979) 5.28
Modification of Streptococcus faecalis sex pheromones after acquisition of plasmid DNA. Proc Natl Acad Sci U S A (1983) 5.27
A cloning vector able to replicate in Escherichia coli and Streptococcus sanguis. Gene (1982) 5.13
Conjugative transposons and the dissemination of antibiotic resistance in streptococci. Annu Rev Microbiol (1986) 5.08
Evidence for clonal spread of a single strain of beta-lactamase-producing Enterococcus (Streptococcus) faecalis to six hospitals in five states. J Infect Dis (1991) 4.82
Strand-specific supercoiled DNA-protein relaxation complexes: comparison of the complexes of bacterial plasmids ColE1 and ColE2. Proc Natl Acad Sci U S A (1971) 4.76
Recombination-deficient mutant of Streptococcus faecalis. J Bacteriol (1980) 4.60
Isolation and characterization of plasmid deoxyribonucleic acid from Streptococcus mutans. J Bacteriol (1973) 4.59
Characterization of a plasmid determining resistance to erythromycin, lincomycin, and vernamycin Balpha in a strain Streptococcus pyogenes. Antimicrob Agents Chemother (1974) 4.47
Isolation of supercoiled colicinogenic factor E 1 DNA sensitive to ribonuclease and alkali. Proc Natl Acad Sci U S A (1972) 4.46
Plasmid-determined tetracycline resistance in Streptococcus faecalis: evidence for gene amplification during growth in presence of tetracycline. Proc Natl Acad Sci U S A (1975) 4.21
Is pneumonia really the old man's friend? Two-year prognosis after community-acquired pneumonia. Lancet (1993) 3.89
Antibiotic susceptibility profiles of Escherichia coli strains lacking multidrug efflux pump genes. Antimicrob Agents Chemother (2001) 3.87
Streptococcus faecalis sex pheromone (cAM373) also produced by Staphylococcus aureus and identification of a conjugative transposon (Tn918). J Bacteriol (1985) 3.84
Hemolysin of Streptococcus faecalis subspecies zymogenes contributes to virulence in mice. Infect Immun (1984) 3.83
Plasmid content of Streptococcus faecalis strain 39-5 and identification of a pheromone (cPD1)-induced surface antigen. J Gen Microbiol (1983) 3.80
Genetic analysis of the pAD1 pheromone response in Streptococcus faecalis, using transposon Tn917 as an insertional mutagen. J Bacteriol (1984) 3.69
Outbreak of multidrug-resistant Enterococcus faecium with transferable vanB class vancomycin resistance. J Clin Microbiol (1994) 3.61
Plasmid-associated hemolysin and aggregation substance production contribute to virulence in experimental enterococcal endocarditis. Antimicrob Agents Chemother (1993) 3.35
"White coat" versus "sustained" borderline hypertension in Tecumseh, Michigan. Hypertension (1990) 3.30
Genetic organization of the bacterial conjugative transposon Tn916. J Bacteriol (1988) 3.18
Direct inhibition of Col E 1 plasmid DNA replication in Escherichia coli by rifampicin. Nat New Biol (1972) 3.05
Nucleotide sequence of the 18-kb conjugative transposon Tn916 from Enterococcus faecalis. Plasmid (1994) 3.01
Plasmid-determined resistance to erythromycin: comparison of strains of streptococcus faecalis and streptococcus pyogenes with regard to plasmid hmology and resistance inducibility. Antimicrob Agents Chemother (1975) 2.91
Transfer functions of the Streptococcus faecalis plasmid pAD1: organization of plasmid DNA encoding response to sex pheromone. J Bacteriol (1987) 2.87
Conjugative transfer of R-plasmids from Streptococcus faecalis to Staphylococcus aureus. Antimicrob Agents Chemother (1982) 2.85
Evidence for conjugal transfer of a Streptococcus faecalis transposon (Tn916) from a chromosomal site in the absence of plasmid DNA. Cold Spring Harb Symp Quant Biol (1981) 2.80
Plasmid-determined tetracycline resistance in Streptococcus faecalis: tandemly repeated resistance determinants in amplified forms of pAMalpha1 DNA. J Mol Biol (1976) 2.79
DNA hybridization and contour-clamped homogeneous electric field electrophoresis for identification of enterococci to the species level. J Clin Microbiol (1995) 2.69
A transposon (Tn917) in Streptococcus faecalis that exhibits enhanced transposition during induction of drug resistance. Cold Spring Harb Symp Quant Biol (1979) 2.64
Simple and reliable multiplex PCR assay for surveillance isolates of vancomycin-resistant enterococci. J Clin Microbiol (2000) 2.62
Clonal spread of vancomycin-resistant Enterococcus faecium between patients in three hospitals in two states. J Clin Microbiol (1993) 2.59
High incidence of hemolysin production by Enterococcus (Streptococcus) faecalis strains associated with human parenteral infections. J Clin Microbiol (1987) 2.42
A conjugative transposon (Tn919) in Streptococcus sanguis. Infect Immun (1985) 2.41
Nucleotide sequence of the gelatinase gene (gelE) from Enterococcus faecalis subsp. liquefaciens. Infect Immun (1991) 2.41
Sex pheromone cAD1 in Streptococcus faecalis: induction of a function related to plasmid transfer. J Bacteriol (1980) 2.37
Effects of altered 5'-flanking sequences on the in vivo expression of a Saccharomyces cerevisiae tRNATyr gene. Mol Cell Biol (1984) 2.35
Plasmids and pheromone response of the beta-lactamase producer Streptococcus (Enterococcus) faecalis HH22. Antimicrob Agents Chemother (1988) 2.27
Antibiotic susceptibility of multiply resistant Pseudomonas aeruginosa isolated from patients with cystic fibrosis, including candidates for transplantation. Clin Infect Dis (1996) 2.23
Existence of the colicinogenic factor-sex factor ColI-b-P9 as a supercoiled circular DNA-protein relaxation complex. Biochem Biophys Res Commun (1970) 2.22
Genetic analysis of the pAD1 hemolysin/bacteriocin determinant in Enterococcus faecalis: Tn917 insertional mutagenesis and cloning. J Bacteriol (1990) 2.20
Characterization of plasmids determining hemolysin and bacteriocin production in Streptococcus faecalis 5952. J Bacteriol (1977) 2.16
Identification and characterization of a small sequence located at two sites on the amplifiable tetracycline resistance plasmid pAMalpha1 in Streptococcus faecalis. J Bacteriol (1977) 2.16
High-level resistance to gentamicin in Streptococcus faecalis: risk factors and evidence for exogenous acquisition of infection. J Infect Dis (1986) 2.15
Characterization and comparison of two penicillinase-producing strains of Streptococcus (Enterococcus) faecalis. Antimicrob Agents Chemother (1988) 2.15
The most frequent aminoglycoside resistance mechanisms--changes with time and geographic area: a reflection of aminoglycoside usage patterns? Aminoglycoside Resistance Study Groups. Clin Infect Dis (1997) 2.14
Comparison of restriction enzyme analysis and pulsed-field gradient gel electrophoresis as typing systems for Candida albicans. J Clin Microbiol (1991) 2.12
Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy. Proc Natl Acad Sci U S A (1995) 2.11
Colitis causes bone loss in rats through suppression of bone formation. Gastroenterology (1996) 2.09
Emergence and nosocomial transmission of ampicillin-resistant enterococci. Antimicrob Agents Chemother (1992) 2.07
Physiological characterization of polar Tn5-induced isoleucine-valine auxotrophs in Escherichia coli K.12: evidence for an internal promoter in the ilvOGEDA operon. Genetics (1979) 2.07
Molecular epidemiology of beta-lactamase-producing enterococci. Antimicrob Agents Chemother (1990) 2.06
Analysis of plasmid deoxyribonucleic acid in a cariogenic strain of Streptococcus faecalis: an approach to identifying genetic determinants on cryptic plasmids. J Bacteriol (1977) 2.06
Characterization of antimicrobial resistance in enterococci of animal origin. Antimicrob Agents Chemother (1995) 2.05
Serious infection due to beta-lactamase-producing Streptococcus faecalis with high-level resistance to gentamicin. J Infect Dis (1988) 2.03
Broad geographical distribution of a cytotoxin gene mediating beta-hemolysis and bacteriocin activity among Streptococcus faecalis strains. Infect Immun (1983) 2.02
Regulation of the pAD1 sex pheromone response in Enterococcus faecalis: construction and characterization of lacZ transcriptional fusions in a key control region of the plasmid. J Bacteriol (1988) 1.94
Determinants of vancomycin resistance and mortality rates in enterococcal bacteremia. a prospective multicenter study. Ann Intern Med (2001) 1.94
Reversible peripartum liver failure: a new perspective on the diagnosis, treatment, and cause of acute fatty liver of pregnancy, based on 28 consecutive cases. Am J Obstet Gynecol (1999) 1.92
Isolation and structure of bacterial sex pheromone, cPD1. Science (1984) 1.92
Identification of pheromone-induced surface proteins in Streptococcus faecalis and evidence of a role for lipoteichoic acid in formation of mating aggregates. J Bacteriol (1986) 1.90
Characterization of the tet(M) determinant of Tn916: evidence for regulation by transcription attenuation. Antimicrob Agents Chemother (1992) 1.89
Identification of a gene, rgg, which regulates expression of glucosyltransferase and influences the Spp phenotype of Streptococcus gordonii Challis. J Bacteriol (1992) 1.89
Characterization of a small plasmid determining resistance to erythromycin, lincomycin, and vernamycin Balpha in a strain of Streptococcus sanguis isolated from dental plaque. Antimicrob Agents Chemother (1978) 1.89
Genetic structure of the Enterococcus faecalis plasmid pAD1-encoded cytolytic toxin system and its relationship to lantibiotic determinants. J Bacteriol (1994) 1.87
Salmonella typhimurium mutants defective in acetohydroxy acid synthases I and II. J Bacteriol (1980) 1.87
Antimicrobial resistance in enterococci isolated from Turkey flocks fed virginiamycin. Antimicrob Agents Chemother (1998) 1.87
Cardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complex. J Biol Chem (1995) 1.83
Bacteremia in narcotic addicts at the Detroit Medical Center. II. Infectious endocarditis: a prospective comparative study. Rev Infect Dis (1986) 1.82
A nosocomial outbreak of Branhamella catarrhalis confirmed by restriction endonuclease analysis. J Infect Dis (1988) 1.81
Nosocomial acquisition of Candida albicans: an epidemiologic study. J Infect Dis (1993) 1.81