Published in Proc Natl Acad Sci U S A on September 01, 1972
Replication of colicin E1 plasmid DNA in cell extracts. Proc Natl Acad Sci U S A (1974) 7.41
Structure and transcription of the nopaline synthase gene region of T-DNA. Nucleic Acids Res (1983) 6.55
Nature of R-factor replication in the presence of chloramphenicol. Proc Natl Acad Sci U S A (1975) 5.64
Origin of replication of colicin E1 plasmid DNA. Proc Natl Acad Sci U S A (1977) 5.38
Characterization of hybrid plasmids carrying individual ribosomal ribonucleic acid transcription units of Escherichia coli. J Bacteriol (1977) 5.37
Reconstitution of an Escherichia coli repair endonuclease activity from the separated uvrA+ and uvrB+/uvrC+ gene products. Proc Natl Acad Sci U S A (1978) 3.71
Replication of colicin E1 plasmid DNA added to cell extracts. Proc Natl Acad Sci U S A (1975) 3.66
Degradation of DNA RNA hybrids by ribonuclease H and DNA polymerases of cellular and viral origin. Proc Natl Acad Sci U S A (1972) 3.58
Regulation of plasmid replication. Microbiol Rev (1984) 3.55
Replication of colicin E1 plasmid DNA in cell extracts. II. Selective synthesis of early replicative intermediates. Proc Natl Acad Sci U S A (1974) 3.55
Colicinogeny and related phenomena. Bacteriol Rev (1975) 3.51
Studies on reverse transcriptase of RNA tumor viruses III. Properties of purified Moloney murine leukemia virus DNA polymerase and associated RNase H. J Virol (1975) 3.31
Cloning and expression of the Bacillus thuringiensis crystal protein gene in Escherichia coli. Proc Natl Acad Sci U S A (1981) 3.19
Isolation and function of the gene A initiator of bacteriophage phi-chi 174, a highly specific DNA endonuclease. Proc Natl Acad Sci U S A (1974) 2.97
Recombination between higher plant DNA and the Ti plasmid of Agrobacterium tumefaciens. Proc Natl Acad Sci U S A (1980) 2.33
Physical characterization of ten R plasmids obtained from an outbreak of nosocomial Klebsiella pneumoniae infections. Antimicrob Agents Chemother (1979) 2.21
Proteins encoded by Agrobacterium tumefaciens Ti plasmid DNA (T-DNA) in crown gall tumors. Proc Natl Acad Sci U S A (1980) 2.07
The presence of ribonucleotides in mature closed-circular mitochondrial DNA. Proc Natl Acad Sci U S A (1973) 2.05
Tumor induction by Agrobacterium rhizogenes involves the transfer of plasmid DNA to the plant genome. Proc Natl Acad Sci U S A (1982) 1.96
Human transferrin: cDNA characterization and chromosomal localization. Proc Natl Acad Sci U S A (1984) 1.85
DNA double-strand breaks and alkali-labile bonds produced by bleomycin. Nucleic Acids Res (1977) 1.68
Replication of colicin E1 plasmid DNA in vivo requires no plasmid-encoded proteins. J Bacteriol (1978) 1.63
Transposon Mutagenesis of Azospirillum brasilense and Azospirillum lipoferum: Physical Analysis of Tn5 and Tn5-Mob Insertion Mutants. Appl Environ Microbiol (1987) 1.55
Chromosomal replication origins (oriC) of Enterobacter aerogenes and Klebsiella pneumoniae are functional in Escherichia coli. J Bacteriol (1982) 1.54
Influence of protein and ribonucleic acid synthesis on the replication of the bacteriocinogenic factor Clo DF13 in Escherichia coli cells and minicells. J Bacteriol (1974) 1.52
Reinitiation of deoxyribonucleic acid synthesis by deoxyribonucleic acid initiation mutants of Escherichia coli: role of ribonucleic acid synthesis, protein synthesis, and cell division. J Bacteriol (1975) 1.45
Succinamopine: a new crown gall opine. J Bacteriol (1984) 1.39
Identification and characterization of human haptoglobin cDNA. Proc Natl Acad Sci U S A (1983) 1.35
RNA-linked DNA fragments in vitro. Proc Natl Acad Sci U S A (1973) 1.34
Methylation of the T-DNA in Agrobacterium tumefaciens and in several crown gall tumors. Nucleic Acids Res (1983) 1.30
Antagonism of the B subunit of DNA gyrase eliminates plasmids pBR322 and pMG110 from Escherichia coli. J Bacteriol (1982) 1.29
Plasmid for tetracycline resistance in Staphylococcus epidermidis. Antimicrob Agents Chemother (1973) 1.21
Nucleotide sequence of an insertion sequence (IS) element identified in the T-DNA region of a spontaneous variant of the Ti-plasmid pTiT37. Nucleic Acids Res (1986) 1.21
Size and base composition of RNA in supercoiled plasmid DNA. Proc Natl Acad Sci U S A (1973) 1.19
Identification and characterization of a DNA primase activity present in herpes simplex virus type 1-infected HeLa cells. J Virol (1988) 1.16
Escherichia coli mutants suppressing replication-defective mutations of the ColE1 plasmid. Proc Natl Acad Sci U S A (1984) 1.16
Enhanced transformation of human cells by UV-irradiated pSV2 plasmids. Mol Cell Biol (1984) 1.15
Purification of the alpha subunit of avian myeloblastosis virus DNA polymerase by polyuridylic acid-sepharose. J Virol (1976) 1.12
Review: ethidium fluorescence assay. Part II. Enzymatic studies and DNA-protein interactions. Nucleic Acids Res (1979) 1.09
New mini-ColE1 as a molecular cloning vehicle. J Bacteriol (1977) 1.05
HindII and HindIII restriction maps of the attphi80-tonB-trp region of the Escherichia coli genome, and location of the tonB gene. J Bacteriol (1978) 0.99
Conjugal deoxyribonucleic acid replication by Excherichia coli K-12: effect of chloramphenicol and rifampin. J Bacteriol (1973) 0.97
Purification of ribonuclease H as a factor required for initiation of in vitro Co1E1 DNA replication. Nucleic Acids Res (1982) 0.97
Replicative intermediates of colicin E1 plasmid DNA in minicells. Proc Natl Acad Sci U S A (1975) 0.95
Double-strand breaks from single photochemical events in DNA containing 5-bromouracil. Biophys J (1978) 0.94
Replication of thermosensitive Rts1 plasmid deoxyribonucleic acid at the nonpermissive temperature. J Bacteriol (1977) 0.93
Tales of conjugation and sex pheromones: A plasmid and enterococcal odyssey. Mob Genet Elements (2011) 0.88
Short deoxyribonucleic acid repair patch length in Escherichia coli is determined by the processive mechanism of deoxyribonucleic acid polymerase I. J Bacteriol (1981) 0.86
Replication of colicinogenic factor E 1 DNA: evidence for a discontinuous replication mechanism. Nucleic Acids Res (1974) 0.83
Strand breakage in solutions of DNA and ethidium bromide exposed to visible light. Nucleic Acids Res (1977) 0.80
Effect of inhibitors of ribonucleic acid and protein synthesis on the cyclic adenosine monophosphate stimulation of plasmid ColE1 replication. J Bacteriol (1974) 0.79
Isolation of behavioral mutants of Azospirillum brasilense by using Tn5 lacZ. Appl Environ Microbiol (1990) 0.79
Cloning and expression in Escherichia coli of the Azospirillum brasilense Sp7 gene encoding ampicillin resistance. Appl Environ Microbiol (1989) 0.77
Ribonuclease-sensitivity of covalently closed rat liver mitochondrial deoxyribonucleic acid. Biochem J (1974) 0.76
Supercoiled circular DNA-protein complex in Escherichia coli: purification and induced conversion to an opern circular DNA form. Proc Natl Acad Sci U S A (1969) 71.62
A dye-buoyant-density method for the detection and isolation of closed circular duplex DNA: the closed circular DNA in HeLa cells. Proc Natl Acad Sci U S A (1967) 48.10
Properties of a supercoiled deoxyribonucleic acid-protein relaxation complex and strand specificity of the relaxation event. Biochemistry (1970) 26.22
Circular DNA forms of colicinogenic factors E1, E2 and E3 from Escherichia coli. J Mol Biol (1968) 23.73
Effect of growth conditions on the formation of the relaxation complex of supercoiled ColE1 deoxyribonucleic acid and protein in Escherichia coli. J Bacteriol (1972) 9.50
DNA polymerase as a requirement for the maintenance of the bacterial plasmid colicinogenic factor E1. Biochem Biophys Res Commun (1970) 8.73
RNA synthesis initiates in vitro conversion of M13 DNA to its replicative form. Proc Natl Acad Sci U S A (1972) 8.09
Mode of action of rafamycin on the RNA polymerase reaction. Biochim Biophys Acta (1968) 8.01
Structure of replicating simian virus 40 deoxyribonucleic acid molecules. J Virol (1971) 6.74
A possible role for RNA polymerase in the initiation of M13 DNA synthesis. Proc Natl Acad Sci U S A (1971) 6.71
Evidence for the direct involvement of RNA in the initiation of DNA replication in Escherichia coli 15T. J Mol Biol (1972) 5.73
Strand-specific supercoiled DNA-protein relaxation complexes: comparison of the complexes of bacterial plasmids ColE1 and ColE2. Proc Natl Acad Sci U S A (1971) 4.76
Direct inhibition of Col E 1 plasmid DNA replication in Escherichia coli by rifampicin. Nat New Biol (1972) 3.05
Ribonuclease H. An enzyme degrading the RNA moiety of DNA-RNA hybrids. Eur J Biochem (1970) 2.81
Transcription: role in the initiation and replication of DNA synthesis in Escherichia coli and phiX174. Biochim Biophys Acta (1971) 2.35
Initiation of the replication of single-stranded DNA by Escherichia coli DNA polymerase. Cold Spring Harb Symp Quant Biol (1968) 2.04
Deoxyribonucleic acid polymerase II of Escherichia coli. II. Studies of the requirements and the structure of the deoxyribonucleic acid product. J Biol Chem (1972) 1.32
Inhibition of plasmid DNA replication by rifampin in Salmonella pullorum. Biochem Biophys Res Commun (1972) 1.28
Requirement for ribonucleic acid synthesis for deoxyribonucleic acid replication in bacteria. Nature (1966) 1.11
Supercoiled circular DNA-protein complex in Escherichia coli: purification and induced conversion to an opern circular DNA form. Proc Natl Acad Sci U S A (1969) 71.62
Nature of Col E 1 plasmid replication in Escherichia coli in the presence of the chloramphenicol. J Bacteriol (1972) 46.61
Broad host range DNA cloning system for gram-negative bacteria: construction of a gene bank of Rhizobium meliloti. Proc Natl Acad Sci U S A (1980) 45.02
Replication of an origin-containing derivative of plasmid RK2 dependent on a plasmid function provided in trans. Proc Natl Acad Sci U S A (1979) 44.75
Plasmid ColEl as a molecular vehicle for cloning and amplification of DNA. Proc Natl Acad Sci U S A (1974) 32.46
Stimulation by cyclic adenosine monophosphate of plasmid deoxyribonucleic acid replication and catabolite repression of the plasmid deoxyribonucleic acid-protein relaxation complex. J Bacteriol (1973) 30.43
Firefly luciferase gene: structure and expression in mammalian cells. Mol Cell Biol (1987) 26.70
Properties of a supercoiled deoxyribonucleic acid-protein relaxation complex and strand specificity of the relaxation event. Biochemistry (1970) 26.22
Circular DNA forms of colicinogenic factors E1, E2 and E3 from Escherichia coli. J Mol Biol (1968) 23.73
Characterization of multiple circular DNA forms of colicinogenic factor E-1 from Proteus mirabilis. Biochemistry (1968) 14.82
Plasmid cloning vehicles derived from plasmids ColE1, F, R6K, and RK2. Methods Enzymol (1979) 13.61
Characterization of three plasmid deoxyribonucleic acid molecules in a strain of Streptococcus faecalis: identification of a plasmid determining erythromycin resistance. J Bacteriol (1974) 12.44
Plasmids related to the broad host range vector, pRK290, useful for gene cloning and for monitoring gene expression. Plasmid (1985) 11.74
Evidence for a chromosome-borne resistance transposon (Tn916) in Streptococcus faecalis that is capable of "conjugal" transfer in the absence of a conjugative plasmid. J Bacteriol (1981) 11.15
Evidence for circular DNA forms of a bacterial plasmid. Proc Natl Acad Sci U S A (1967) 10.45
Circular DNA. Annu Rev Biochem (1971) 9.75
Induced cell aggregation and mating in Streptococcus faecalis: evidence for a bacterial sex pheromone. Proc Natl Acad Sci U S A (1978) 9.67
Effect of growth conditions on the formation of the relaxation complex of supercoiled ColE1 deoxyribonucleic acid and protein in Escherichia coli. J Bacteriol (1972) 9.50
DNA polymerase as a requirement for the maintenance of the bacterial plasmid colicinogenic factor E1. Biochem Biophys Res Commun (1970) 8.73
Transmissible toxin (hemolysin) plasmid in Streptococcus faecalis and its mobilization of a noninfectious drug resistance plasmid. J Bacteriol (1975) 8.65
Circular DNA forms of a bacterial sex factor. Proc Natl Acad Sci U S A (1967) 8.55
Trans-complementation-dependent replication of a low molecular weight origin fragment from plasmid R6K. Cell (1978) 8.28
The importance of repairing stalled replication forks. Nature (2000) 7.93
Plasmids, drug resistance, and gene transfer in the genus Streptococcus. Microbiol Rev (1981) 7.86
Plasmid transfer in Streptococcus faecalis: production of multiple sex pheromones by recipients. Plasmid (1979) 7.20
Characterization of a mini-ColC1 plasmid. J Bacteriol (1976) 7.20
Effect of Rec mutations on the activity of colicinogenic factors. J Bacteriol (1967) 7.19
Replication of a bacterial plasmid and an episome in Escherichia coli. Biochemistry (1970) 7.19
Mapping of Streptococcus faecalis plasmids pAD1 and pAD2 and studies relating to transposition of Tn917. J Bacteriol (1982) 7.03
Complete nucleotide sequence of macrolide-lincosamide-streptogramin B-resistance transposon Tn917 in Streptococcus faecalis. J Bacteriol (1985) 7.00
Regeneration of insertionally inactivated streptococcal DNA fragments after excision of transposon Tn916 in Escherichia coli: strategy for targeting and cloning of genes from gram-positive bacteria. J Bacteriol (1984) 6.82
Unidirectional replication of the P-group plasmid RK2. Biochim Biophys Acta (1977) 6.17
Properties of erythromycin-inducible transposon Tn917 in Streptococcus faecalis. J Bacteriol (1980) 6.06
Transient and stable expression of the firefly luciferase gene in plant cells and transgenic plants. Science (1986) 5.97
Molecular cloning of a new transforming gene from a chemically transformed human cell line. Nature (1984) 5.85
Heme biosynthesis in Rhizobium. Identification of a cloned gene coding for delta-aminolevulinic acid synthetase from Rhizobium meliloti. J Biol Chem (1982) 5.80
Method for the isolation of the replication region of a bacterial replicon: construction of a mini-F'kn plasmid. J Bacteriol (1976) 5.75
Purification and characterization of colicin E2 and colicin E3. J Biol Chem (1967) 5.74
A transposon in Streptococcus faecalis with fertility properties. Nature (1982) 5.65
A catenated DNA molecule as an intermediate in the replication of the resistance transfer factor R6K in Escherichia coli. Biochem Biophys Res Commun (1973) 5.47
Regions of broad-host-range plasmid RK2 which are essential for replication and maintenance. J Bacteriol (1980) 5.45
Highly efficient protoplast transformation system for Streptococcus faecalis and a new Escherichia coli-S. faecalis shuttle vector. J Bacteriol (1986) 5.35
Novel shuttle plasmid vehicles for Escherichia-Streptococcus transgeneric cloning. Gene (1983) 5.30
Properties of a normal mouse cell DNA sequence (sarc) homologous to the src sequence of Moloney sarcoma virus. Science (1980) 5.30
Plasmid-related transmissibility and multiple drug resistance in Streptococcus faecalis subsp. zymogenes strain DS16. Antimicrob Agents Chemother (1979) 5.28
Modification of Streptococcus faecalis sex pheromones after acquisition of plasmid DNA. Proc Natl Acad Sci U S A (1983) 5.27
Temperature-sensitive mutants for the replication of plasmids in Escherichia coli: requirement for deoxyribonucleic acid polymerase I in the replication of the plasmid ColE 1 . J Bacteriol (1973) 5.24
Gene cloning and containment properties of plasmid Col E1 and its derivatives. Science (1977) 5.21
Comparative study of the events associated with colicin induction. J Bacteriol (1967) 5.14
A cloning vector able to replicate in Escherichia coli and Streptococcus sanguis. Gene (1982) 5.13
Conjugative transposons and the dissemination of antibiotic resistance in streptococci. Annu Rev Microbiol (1986) 5.08
Strand-specific supercoiled DNA-protein relaxation complexes: comparison of the complexes of bacterial plasmids ColE1 and ColE2. Proc Natl Acad Sci U S A (1971) 4.76
Suppression of Co1E1 replication properties by the Inc P-1 plasmid RK2 in hybrid plasmids constructed in vitro. J Mol Biol (1979) 4.69
Recombination-deficient mutant of Streptococcus faecalis. J Bacteriol (1980) 4.60
Isolation and characterization of plasmid deoxyribonucleic acid from Streptococcus mutans. J Bacteriol (1973) 4.59
Characterization of a human gene conferring sensitivity to infection by gibbon ape leukemia virus. Cell Growth Differ (1990) 4.50
The DNA-protein relaxation complex of the plasmid RK2: location of the site-specific nick in the region of the proposed origin of transfer. Mol Gen Genet (1979) 4.48
Characterization of a plasmid determining resistance to erythromycin, lincomycin, and vernamycin Balpha in a strain Streptococcus pyogenes. Antimicrob Agents Chemother (1974) 4.47
A haemoprotein with kinase activity encoded by the oxygen sensor of Rhizobium meliloti. Nature (1991) 4.45
Generation in vitro of deletions in the broad host range plasmid RK2 using phage Mu insertions and a restriction endonuclease. Gene (1976) 4.35
Physical and genetic studies with restriction endonucleases on the broad host-range plasmid RK2. Mol Gen Genet (1977) 4.28
Purification and characterization of colicin E1. J Biol Chem (1971) 4.27
Activation of the transforming potential of a normal cell sequence: a molecular model for oncogenesis. Science (1981) 4.27
Unidirectional replication of plasmid ColE1 DNA. Nature (1974) 4.27
Complete nucleotide sequence of Birmingham IncP alpha plasmids. Compilation and comparative analysis. J Mol Biol (1994) 4.23
Plasmid-determined tetracycline resistance in Streptococcus faecalis: evidence for gene amplification during growth in presence of tetracycline. Proc Natl Acad Sci U S A (1975) 4.21
Mechanism of met oncogene activation. Cell (1986) 4.20
Generation of higher multiple circular DNA forms in bacteria. Proc Natl Acad Sci U S A (1968) 3.98
Regions of broad-host-range plasmid RK2 involved in replication and stable maintenance in nine species of gram-negative bacteria. J Bacteriol (1985) 3.93
Catalysis by site-specific recombinases. Trends Genet (1992) 3.86
Streptococcus faecalis sex pheromone (cAM373) also produced by Staphylococcus aureus and identification of a conjugative transposon (Tn918). J Bacteriol (1985) 3.84
Hemolysin of Streptococcus faecalis subspecies zymogenes contributes to virulence in mice. Infect Immun (1984) 3.83
Plasmid content of Streptococcus faecalis strain 39-5 and identification of a pheromone (cPD1)-induced surface antigen. J Gen Microbiol (1983) 3.80
Genetic analysis of the pAD1 pheromone response in Streptococcus faecalis, using transposon Tn917 as an insertional mutagen. J Bacteriol (1984) 3.69
Multimerization of high copy number plasmids causes instability: CoIE1 encodes a determinant essential for plasmid monomerization and stability. Cell (1984) 3.65
The human met oncogene is related to the tyrosine kinase oncogenes. Nature (1985) 3.46
Rhizobium meliloti genes required for nodule development are related to chromosomal virulence genes in Agrobacterium tumefaciens. Proc Natl Acad Sci U S A (1986) 3.38
Cloning of firefly luciferase cDNA and the expression of active luciferase in Escherichia coli. Proc Natl Acad Sci U S A (1985) 3.35
Plasmid-associated hemolysin and aggregation substance production contribute to virulence in experimental enterococcal endocarditis. Antimicrob Agents Chemother (1993) 3.35
Biological activity of cloned Moloney sarcoma virus DNA: Terminally redundant sequences may enhance transformation efficiency. Proc Natl Acad Sci U S A (1980) 3.29
Structural relationships among Rhizobium meliloti symbiotic promoters. Cell (1983) 3.23
Genetic organization of the bacterial conjugative transposon Tn916. J Bacteriol (1988) 3.18
Direct inhibition of Col E 1 plasmid DNA replication in Escherichia coli by rifampicin. Nat New Biol (1972) 3.05
Nucleotide sequence of the 18-kb conjugative transposon Tn916 from Enterococcus faecalis. Plasmid (1994) 3.01
Construction of plasmid cloning vehicles that promote gene expression from the bacteriophage lambda pL promoter. Gene (1979) 3.00
Molecular vehicle properties of the broad host range plasmid RK2. Science (1975) 2.97
Plasmid-determined resistance to erythromycin: comparison of strains of streptococcus faecalis and streptococcus pyogenes with regard to plasmid hmology and resistance inducibility. Antimicrob Agents Chemother (1975) 2.91
Isolation and characterization of the recA gene of Rhizobium meliloti. J Bacteriol (1983) 2.89
Transfer functions of the Streptococcus faecalis plasmid pAD1: organization of plasmid DNA encoding response to sex pheromone. J Bacteriol (1987) 2.87
Conjugative transfer of R-plasmids from Streptococcus faecalis to Staphylococcus aureus. Antimicrob Agents Chemother (1982) 2.85
Strand and site specificity of the relaxation event for the relaxation complex of the antibiotic resistance plasmid R6K. Biochemistry (1974) 2.81
Evidence for conjugal transfer of a Streptococcus faecalis transposon (Tn916) from a chromosomal site in the absence of plasmid DNA. Cold Spring Harb Symp Quant Biol (1981) 2.80
ColE1 plasmid mobility and relaxation complex. Nature (1978) 2.79
Plasmid-determined tetracycline resistance in Streptococcus faecalis: tandemly repeated resistance determinants in amplified forms of pAMalpha1 DNA. J Mol Biol (1976) 2.79