Published in Genes Dev on November 01, 2000
Regulation of TORC1 by Rag GTPases in nutrient response. Nat Cell Biol (2008) 8.92
Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E. Genes Dev (2002) 8.31
Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress. Mol Cell (2010) 7.59
The immunosuppressant rapamycin mimics a starvation-like signal distinct from amino acid and glucose deprivation. Mol Cell Biol (2002) 7.44
Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR. Proc Natl Acad Sci U S A (2001) 6.99
mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E. Mol Cell Biol (2004) 5.46
Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling. Proc Natl Acad Sci U S A (2002) 4.93
TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth. Genes Dev (2001) 4.68
An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice. Proc Natl Acad Sci U S A (2001) 4.62
Effects on survival of BAP1 and PBRM1 mutations in sporadic clear-cell renal-cell carcinoma: a retrospective analysis with independent validation. Lancet Oncol (2013) 4.24
4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila. Cell (2009) 4.20
With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging. Cell Metab (2010) 4.11
mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells. Mol Cell Biol (2004) 3.72
The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila. Genes Dev (2004) 3.59
Nutrient control of gene expression in Drosophila: microarray analysis of starvation and sugar-dependent response. EMBO J (2002) 3.58
The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila. J Cell Biol (2008) 3.37
Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases. EMBO J (2004) 3.29
Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks. Mol Cell Biol (2011) 3.28
Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development. Mol Cell Biol (2004) 3.20
The target of rapamycin (TOR) proteins. Proc Natl Acad Sci U S A (2001) 3.16
Amino acid regulation of TOR complex 1. Am J Physiol Endocrinol Metab (2008) 3.03
Sfp1 is a stress- and nutrient-sensitive regulator of ribosomal protein gene expression. Proc Natl Acad Sci U S A (2004) 2.99
mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability. Genes Dev (2004) 2.96
Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. J Clin Invest (2011) 2.90
Drosophila Brain Tumor is a translational repressor. Genes Dev (2001) 2.90
Lethality of Drosophila lacking TSC tumor suppressor function rescued by reducing dS6K signaling. Genes Dev (2002) 2.87
GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer. Nature (2009) 2.77
Elucidating TOR signaling and rapamycin action: lessons from Saccharomyces cerevisiae. Microbiol Mol Biol Rev (2002) 2.69
mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo. Proc Natl Acad Sci U S A (2003) 2.68
Expression and disruption of the Arabidopsis TOR (target of rapamycin) gene. Proc Natl Acad Sci U S A (2002) 2.62
HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans. PLoS Genet (2009) 2.60
Signaling by target of rapamycin proteins in cell growth control. Microbiol Mol Biol Rev (2005) 2.56
A protein kinase B-dependent and rapamycin-sensitive pathway controls skeletal muscle growth but not fiber type specification. Proc Natl Acad Sci U S A (2002) 2.53
TOR coordinates bulk and targeted endocytosis in the Drosophila melanogaster fat body to regulate cell growth. J Cell Biol (2006) 2.24
The Arabidopsis TOR kinase links plant growth, yield, stress resistance and mRNA translation. EMBO Rep (2007) 2.15
RNA-polymerase-I-directed rDNA transcription, life and works. Trends Biochem Sci (2005) 2.13
Growth and aging: a common molecular mechanism. Aging (Albany NY) (2009) 2.13
PRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis. PLoS One (2007) 2.07
Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin. Proc Natl Acad Sci U S A (2002) 2.06
ATG1, an autophagy regulator, inhibits cell growth by negatively regulating S6 kinase. EMBO Rep (2007) 1.99
Phosphorylation of eukaryotic translation initiation factor 4E is critical for growth. Mol Cell Biol (2002) 1.92
The cell biology of autophagy in metazoans: a developing story. Development (2008) 1.76
Myocardial AKT: the omnipresent nexus. Physiol Rev (2011) 1.76
Effect of insulin and 20-hydroxyecdysone in the fat body of the yellow fever mosquito, Aedes aegypti. Insect Biochem Mol Biol (2007) 1.75
Schizosaccharomyces pombe AGC family kinase Gad8p forms a conserved signaling module with TOR and PDK1-like kinases. EMBO J (2003) 1.71
Transformed Drosophila cells evade diet-mediated insulin resistance through wingless signaling. Cell (2013) 1.69
Amino acid transceptors: gate keepers of nutrient exchange and regulators of nutrient signaling. Am J Physiol Endocrinol Metab (2009) 1.68
The bantam gene regulates Drosophila growth. Genetics (2002) 1.62
Tsc2 is not a critical target of Akt during normal Drosophila development. Genes Dev (2004) 1.57
TOR pathway: linking nutrient sensing to life span. Sci Aging Knowledge Environ (2004) 1.55
Drosophila target of rapamycin kinase functions as a multimer. Genetics (2005) 1.50
DAF-16 and TCER-1 Facilitate Adaptation to Germline Loss by Restoring Lipid Homeostasis and Repressing Reproductive Physiology in C. elegans. PLoS Genet (2016) 1.47
Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation. J Exp Med (2001) 1.47
Differential requirement of mTOR in postmitotic tissues and tumorigenesis. Sci Signal (2009) 1.47
REPTOR and REPTOR-BP Regulate Organismal Metabolism and Transcription Downstream of TORC1. Dev Cell (2015) 1.46
Organ size control by Hippo and TOR pathways. Curr Biol (2012) 1.45
Transcriptional control of cellular metabolism by mTOR signaling. Cancer Res (2011) 1.44
Deletion of ribosomal S6 kinases does not attenuate pathological, physiological, or insulin-like growth factor 1 receptor-phosphoinositide 3-kinase-induced cardiac hypertrophy. Mol Cell Biol (2004) 1.43
Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope. EMBO J (2002) 1.42
Nutrient regulation of the mTOR complex 1 signaling pathway. Mol Cells (2013) 1.42
Selective pharmacogenetic inhibition of mammalian target of Rapamycin complex I (mTORC1) blocks long-term synaptic plasticity and memory storage. Proc Natl Acad Sci U S A (2011) 1.41
WAC Regulates mTOR Activity by Acting as an Adaptor for the TTT and Pontin/Reptin Complexes. Dev Cell (2016) 1.40
Coordinating growth and maturation - insights from Drosophila. Curr Biol (2011) 1.38
Specific roles of Target of rapamycin in the control of stem cells and their progeny in the Drosophila ovary. Development (2010) 1.37
Intramyocellular fatty-acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster. Cell Metab (2012) 1.34
Interplay between pVHL and mTORC1 pathways in clear-cell renal cell carcinoma. Mol Cancer Res (2011) 1.33
Growing knowledge of the mTOR signaling network. Semin Cell Dev Biol (2014) 1.33
The developmental control of size in insects. Wiley Interdiscip Rev Dev Biol (2013) 1.32
d4eBP acts downstream of both dTOR and dFoxo to modulate cardiac functional aging in Drosophila. Aging Cell (2009) 1.31
Rapamycin inhibits trypanosome cell growth by preventing TOR complex 2 formation. Proc Natl Acad Sci U S A (2008) 1.31
Nutrient-sensing mechanisms across evolution. Cell (2015) 1.30
Partial ablation of adult Drosophila insulin-producing neurons modulates glucose homeostasis and extends life span without insulin resistance. Cell Cycle (2010) 1.29
Target of rapamycin (TOR) signaling controls epithelial morphogenesis in the vertebrate intestine. Dev Biol (2006) 1.29
Opposite effects of tor1 and tor2 on nitrogen starvation responses in fission yeast. Genetics (2006) 1.28
Staying alive: metabolic adaptations to quiescence. Cell Cycle (2012) 1.28
An emerging role for TOR signaling in mammalian tissue and stem cell physiology. Development (2011) 1.27
The target of rapamycin signaling pathway regulates mRNA turnover in the yeast Saccharomyces cerevisiae. Mol Biol Cell (2001) 1.27
Mechanisms of TSC-mediated control of synapse assembly and axon guidance. PLoS One (2007) 1.23
Receptor internalization in yeast requires the Tor2-Rho1 signaling pathway. Mol Biol Cell (2003) 1.23
The C terminus of initiation factor 4E-binding protein 1 contains multiple regulatory features that influence its function and phosphorylation. Mol Cell Biol (2003) 1.22
Role of TOR signaling in aging and related biological processes in Drosophila melanogaster. Exp Gerontol (2010) 1.21
Insulin-induced Drosophila S6 kinase activation requires phosphoinositide 3-kinase and protein kinase B. Biochem J (2003) 1.21
Drosophila TIF-IA is required for ribosome synthesis and cell growth and is regulated by the TOR pathway. J Cell Biol (2007) 1.20
Direct sensing of systemic and nutritional signals by haematopoietic progenitors in Drosophila. Nat Cell Biol (2012) 1.19
Drosophila RNA polymerase III repressor Maf1 controls body size and developmental timing by modulating tRNAiMet synthesis and systemic insulin signaling. Proc Natl Acad Sci U S A (2012) 1.19
Cracking open cell death in the Drosophila ovary. Apoptosis (2009) 1.18
TOR complex 2 is needed for cell cycle progression and anchorage-independent growth of MCF7 and PC3 tumor cells. BMC Cancer (2008) 1.18
TOR signaling is required for amino acid stimulation of early trypsin protein synthesis in the midgut of Aedes aegypti mosquitoes. Insect Biochem Mol Biol (2008) 1.17
Deconvoluting mTOR biology. Cell Cycle (2012) 1.16
A nucleostemin family GTPase, NS3, acts in serotonergic neurons to regulate insulin signaling and control body size. Genes Dev (2008) 1.14
Target of rapamycin regulates development and ribosomal RNA expression through kinase domain in Arabidopsis. Plant Physiol (2011) 1.14
The Drosophila PGC-1 homologue Spargel coordinates mitochondrial activity to insulin signalling. EMBO J (2009) 1.14
Intertissue control of the nucleolus via a myokine-dependent longevity pathway. Cell Rep (2014) 1.13
The Sex Determination Gene transformer Regulates Male-Female Differences in Drosophila Body Size. PLoS Genet (2015) 1.11
The Drosophila deoxyhypusine hydroxylase homologue nero and its target eIF5A are required for cell growth and the regulation of autophagy. J Cell Biol (2009) 1.11
Nutritional control of gene expression in Drosophila larvae via TOR, Myc and a novel cis-regulatory element. BMC Cell Biol (2010) 1.09
Nutrient/TOR-dependent regulation of RNA polymerase III controls tissue and organismal growth in Drosophila. EMBO J (2012) 1.08
A genetic screen for dominant modifiers of a cyclin E hypomorphic mutation identifies novel regulators of S-phase entry in Drosophila. Genetics (2004) 1.07
TOR signaling never gets old: aging, longevity and TORC1 activity. Ageing Res Rev (2010) 1.07
The immunophilin-interacting protein AtFIP37 from Arabidopsis is essential for plant development and is involved in trichome endoreduplication. Plant Physiol (2004) 1.07
The genome sequence of Drosophila melanogaster. Science (2000) 74.32
Analysis of genetic mosaics in developing and adult Drosophila tissues. Development (1993) 13.43
Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast. J Biol Chem (1998) 10.77
Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast. Science (1991) 10.16
Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism. J Biol Chem (1998) 9.37
The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors. Nature (1999) 9.29
Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases. Cell (1992) 8.51
RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1. Proc Natl Acad Sci U S A (1998) 8.03
TOR controls translation initiation and early G1 progression in yeast. Mol Biol Cell (1996) 8.03
Drosophila S6 kinase: a regulator of cell size. Science (1999) 6.76
Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression. Cell (1993) 6.44
Size control in animal development. Cell (1999) 6.39
Coordination of growth and cell division in the Drosophila wing. Cell (1998) 5.93
Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins. Proc Natl Acad Sci U S A (1999) 5.89
The TOR signaling cascade regulates gene expression in response to nutrients. Genes Dev (1999) 5.80
Minutes: mutants of drosophila autonomously affecting cell division rate. Dev Biol (1975) 5.76
Drosophila myc regulates cellular growth during development. Cell (1999) 5.66
Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4. Cell (1999) 5.38
Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB. Nat Cell Biol (1999) 5.00
Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation. Biochem J (1999) 4.80
A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells. Cancer Res (2000) 4.62
PIK-related kinases: DNA repair, recombination, and cell cycle checkpoints. Science (1995) 4.51
Identification and characterization of a yeast nucleolar protein that is similar to a rat liver nucleolar protein. J Cell Biol (1988) 4.42
Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae. Mol Biol Cell (1999) 4.34
Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway. Proc Natl Acad Sci U S A (1998) 3.66
The conserved phosphoinositide 3-kinase pathway determines heart size in mice. EMBO J (2000) 3.64
TOR kinase domains are required for two distinct functions, only one of which is inhibited by rapamycin. Cell (1995) 3.56
Coupling of cell division to cell growth by translational control of the G1 cyclin CLN3 in yeast. Genes Dev (1997) 3.31
A signaling pathway to translational control. Cell (1996) 3.29
Induction of Drosophila eye development by decapentaplegic. Development (1997) 3.12
Rapamycin induces the G0 program of transcriptional repression in yeast by interfering with the TOR signaling pathway. Mol Cell Biol (1998) 2.91
The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene. Cell (1995) 2.88
Environmental control of the cell cycle in Drosophila: nutrition activates mitotic and endoreplicative cells by distinct mechanisms. Development (1998) 2.79
Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor. Curr Biol (1999) 2.76
FKBP12-rapamycin-associated protein (FRAP) autophosphorylates at serine 2481 under translationally repressive conditions. J Biol Chem (2000) 2.72
TOR2 is required for organization of the actin cytoskeleton in yeast. Proc Natl Acad Sci U S A (1996) 2.72
Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR. Curr Biol (2000) 2.70
Amino acid availability regulates p70 S6 kinase and multiple translation factors. Biochem J (1998) 2.65
Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways. Dev Biol (2000) 2.59
Target of rapamycin (TOR): balancing the opposing forces of protein synthesis and degradation. Curr Opin Genet Dev (1999) 2.48
Ectopic cyclin E expression induces premature entry into S phase and disrupts pattern formation in the Drosophila eye imaginal disc. Development (1995) 2.43
Ras1 promotes cellular growth in the Drosophila wing. Cell (2000) 2.42
Multiple independent inputs are required for activation of the p70 S6 kinase. Mol Cell Biol (1995) 2.39
The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling. Curr Opin Cell Biol (1995) 2.09
Connections between growth and the cell cycle. Curr Opin Cell Biol (1998) 2.08
Amino acid-dependent control of p70(s6k). Involvement of tRNA aminoacylation in the regulation. J Biol Chem (1999) 2.08
A Drosophila G1-specific cyclin E homolog exhibits different modes of expression during embryogenesis. Development (1993) 1.91
Mammalian TOR controls one of two kinase pathways acting upon nPKCdelta and nPKCepsilon. J Biol Chem (1999) 1.90
Structural and functional analysis of pp70S6k. Proc Natl Acad Sci U S A (1995) 1.84
E2F-induced S phase requires cyclin E. Genes Dev (1996) 1.71
Nucleolar function and size in cancer cells. Am J Pathol (1998) 1.66
Protein kinases as mediators of phosphoinositide 3-kinase signaling. Mol Pharmacol (2000) 1.59
The FKBP12-rapamycin-binding domain is required for FKBP12-rapamycin-associated protein kinase activity and G1 progression. J Biol Chem (1999) 1.57
Suppression of food intake and growth by amino acids in Drosophila: the role of pumpless, a fat body expressed gene with homology to vertebrate glycine cleavage system. Development (1999) 1.57
ADIPOSE TISSUE OF DROSOPHILA MELANOGASTER. I. AN EXPERIMENTAL STUDY OF LARVAL FAT BODY. J Exp Zool (1965) 1.45
Interaction of RAFT1 with gephyrin required for rapamycin-sensitive signaling. Science (1999) 1.42
The Drosophila p70s6k homolog exhibits conserved regulatory elements and rapamycin sensitivity. Proc Natl Acad Sci U S A (1996) 1.33
Modulation of transcription of rRNA genes by rapamycin. Int J Immunopharmacol (1994) 1.29
Amino acids stimulate phosphorylation of p70S6k and organization of rat adipocytes into multicellular clusters. Am J Physiol (1998) 1.17
Functional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translation. EMBO J (2000) 1.16
Insulin mediates glucose-stimulated phosphorylation of PHAS-I by pancreatic beta cells. An insulin-receptor mechanism for autoregulation of protein synthesis by translation. J Biol Chem (1998) 1.15
TOR signaling regulates microtubule structure and function. Curr Biol (2000) 1.14
Do growth and cell division rates determine cell size in multicellular organisms? J Cell Sci (2000) 1.08
Regulation of the rapamycin and FKBP-target 1/mammalian target of rapamycin and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinase. J Biol Chem (2000) 1.02
Postprandial stimulation of muscle protein synthesis is independent of changes in insulin. Am J Physiol (1997) 1.00
Glucose and amino acids modulate translation factor activation by growth factors in PC12 cells. Biochem J (2000) 0.91
14-3-3tau associates with a translational control factor FKBP12-rapamycin-associated protein in T-cells after stimulation by pervanadate. FEBS Lett (2000) 0.85
Variation of nucleolar area in fat tissue of Drosophila mulleri during development. Cytobios (1995) 0.82
Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k. EMBO J (1997) 5.57
Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis. Science (1997) 4.19
Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family. Proc Natl Acad Sci U S A (1994) 4.16
Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways. Mol Cell Biol (1996) 3.82
Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors. Proc Natl Acad Sci U S A (2001) 2.77
Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor. Curr Biol (1999) 2.76
PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling. Nat Cell Biol (2001) 2.69
Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways. Dev Biol (2000) 2.59
PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism. Cell (1997) 2.50
Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd. Proc Natl Acad Sci U S A (2001) 2.22
Early activation of c-Jun N-terminal kinase and p38 kinase regulate cell survival in response to tumor necrosis factor alpha. J Biol Chem (1998) 2.01
Immunosuppressant PG490 (triptolide) inhibits T-cell interleukin-2 expression at the level of purine-box/nuclear factor of activated T-cells and NF-kappaB transcriptional activation. J Biol Chem (1999) 1.72
Gene expression profiling identifies FKBP39 as an inhibitor of autophagy in larval Drosophila fat body. Cell Death Differ (2007) 1.58
Activation of hPAK65 by caspase cleavage induces some of the morphological and biochemical changes of apoptosis. Proc Natl Acad Sci U S A (1997) 1.48
Environmental bias? Effects of housing conditions, laboratory environment and experimenter on behavioral tests. Genes Brain Behav (2006) 1.35
The nifH gene product is required for the synthesis or stability of the iron-molybdenum cofactor of nitrogenase from Klebsiella pneumoniae. Eur J Biochem (1986) 1.35
Transcriptional regulation of cytoskeletal functions and segmentation by a novel maternal pair-rule gene, lilliputian. Development (2001) 1.32
Recruitment to Golgi membranes of ADP-ribosylation factor 1 is mediated by the cytoplasmic domain of p23. EMBO J (2001) 1.25
The intracerebral distribution of BCNU delivered by surgically implanted biodegradable polymers. J Neurosurg (1992) 1.13
Identification of genes that interact with the sina gene in Drosophila eye development. Proc Natl Acad Sci U S A (1994) 1.03
The secretory pathway from history to the state of the art. Subcell Biochem (2000) 0.99
Inhalation of ultrafine carbon particles triggers biphasic pro-inflammatory response in the mouse lung. Eur Respir J (2006) 0.94
Large-scale analysis of 73 329 physcomitrella plants transformed with different gene disruption libraries: production parameters and mutant phenotypes. Plant Biol (Stuttg) (2005) 0.87
Modulation of human cytomegalovirus immediate-early gene enhancer by mitogen-activated protein kinase kinase kinase-1. J Cell Biochem (2001) 0.86
Isolation of a compound from Eupatorium adenophorum (Spreng.) [Ageratina adenophora (Spreng.)] causing hepatotoxicity in mice. Nat Toxins (1995) 0.85
Active baculovirus recombinant p70s6k and p85s6k produced as a function of the infectious response. J Biol Chem (1993) 0.84
Isolation and identification of a compound from avocado (Persea americana) leaves which causes necrosis of the acinar epithelium of the lactating mammary gland and the myocardium. Nat Toxins (1995) 0.83
A field study conducted at Kidston Gold Mine, to evaluate the impact of arsenic and zinc from mine tailing to grazing cattle. Toxicol Lett (2003) 0.81
Specific activation of glucuronide prodrugs by antibody-targeted enzyme conjugates for cancer therapy. Cancer Res (1992) 0.81
Acute phase response in horses: changes in plasma cation concentrations after localised tissue injury. Vet Rec (1989) 0.80
Role of diuretics, hormonal derangements, and clinical setting of hyponatremia in medical patients. Klin Wochenschr (1988) 0.80
The magical and medicinal usage of Stangeria eriopus in South Africa. J Ethnopharmacol (1994) 0.80
Porphyrins as early biomarkers for arsenic exposure in animals and humans. Cell Mol Biol (Noisy-le-grand) (2002) 0.79
Copper salicylate and copper phenylbutazone as topically applied anti-inflammatory agents in the rat and horse. J Vet Pharmacol Ther (1990) 0.79
Assessment of copper and zinc status of farm horses and training thoroughbreds in south-east Queensland. Aust Vet J (1988) 0.79
Unique toxic peptides isolated from sawfly larvae in three continents. Toxicon (1999) 0.79
Exercise-induced connective tissue turnover and lipid peroxidation in horses. Br Vet J (1994) 0.79
Oligomerization of peptides analogous to the cytoplasmic domains of coatomer receptors revealed by mass spectrometry. Biochemistry (2000) 0.79
The elimination of injected superoxide dismutase from synovial fluid of the horse. Aust Vet J (1989) 0.78
Concentration of ptaquiloside, a major carcinogen in bracken fern (Pteridium spp.), from eastern Australia and from a cultivated worldwide collection held in Sydney, Australia. Nat Toxins (1994) 0.77
Stress response to chronic inflammation in the horse. Equine Vet J (1997) 0.77
Some effects of chronic mercuric chloride intoxication on renal function in a horse. Vet Hum Toxicol (1982) 0.77
Structure of the cytoplasmic domain of p23 in solution: implications for the formation of COPI vesicles. Biochem Biophys Res Commun (2000) 0.77
Vasa praevia--antepartum haemorrhage with sinusoidal fetal heart pattern. Aust N Z J Obstet Gynaecol (1987) 0.76
Effect of palosein (superoxide dismutase) and catalase upon oxygen derived free radical induced degradation of equine synovial fluid. Equine Vet J (1990) 0.75
Phenylbutazone in racing greyhounds: plasma and urinary residues 24 and 48 hours after a single intravenous administration. Aust Vet J (1995) 0.75
Anti-inflammatory drugs inhibit degradation of equine synovial fluid induced by free radicals. Aust Vet J (1991) 0.75
A suspected case of acute copper toxicity in a horse. Aust Vet J (1989) 0.75
Assessment of histamine, bradykinin, prostaglandins E1 and E2 and carrageenin as vascular permeability agents in the horse. J Vet Pharmacol Ther (1991) 0.75
Chronic phenylmercuric acetate toxicity in a horse. Vet Hum Toxicol (1979) 0.75
Kinetics, dose response, tachyphylaxis and cross-tachyphylaxis of vascular leakage induced by endotoxin, zymosan-activated plasma and platelet-activating factor in the horse. J Vet Pharmacol Ther (1995) 0.75
Environmental poisoning: presentation and management. Ther Drug Monit (1998) 0.75
Disposition and urinary excretion of phenylbutazone in normal and febrile greyhounds. Res Vet Sci (1995) 0.75
A nonsurgical method of drainage of pyometra. Aust N Z J Obstet Gynaecol (1988) 0.75
Free radical oxidation products in plasma and synovial fluid of horses with synovial inflammation. Aust Vet J (1993) 0.75
The effect of the acute-phase response on in vitro drug metabolism and plasma protein binding in the horse. Vet Res Commun (1997) 0.75
Superoxide production by stimulated equine polymorphonuclear leukocytes--inhibition by anti-inflammatory drugs. J Vet Pharmacol Ther (1990) 0.75
Prediction in road safety studies: an empirical inquiry. Accid Anal Prev (1991) 0.75
"Madame A is a 30-year-old housewife, gravida X, para Y ...". Obstet Gynecol (1989) 0.75
Kinetics of endotoxin, complement and platelet-activating factor (PAF) induced vascular permeability in greyhounds. J Vet Pharmacol Ther (1994) 0.75
Isolation and characterisation of urushiol components from the Australian native cashew (Semecarpus australiensis). Nat Toxins (1997) 0.75
Effects of inflammation-associated acute-phase response on hepatic and renal indices in the horse. Aust Vet J (1998) 0.75
Lithium treatment reduces the renal kallikrein excretion rate. Kidney Int (1990) 0.75
The effect of inflammation on the disposition of phenylbutazone in thoroughbred horses. J Vet Pharmacol Ther (1996) 0.75
Vascular leakage induced by histamine, bradykinin, serotonin and prostaglandin E2 in greyhounds. Aust Vet J (1993) 0.75
Monthly variation in the plasma copper and zinc concentration of pregnant and non-pregnant mares. Aust Vet J (1988) 0.75