Published in Biochemistry on November 28, 2000
Peptide antimicrobial agents. Clin Microbiol Rev (2006) 6.04
Designing antimicrobial peptides: form follows function. Nat Rev Drug Discov (2011) 4.16
Swarming of Pseudomonas aeruginosa is a complex adaptation leading to increased production of virulence factors and antibiotic resistance. J Bacteriol (2008) 1.98
Adaptive resistance to the "last hope" antibiotics polymyxin B and colistin in Pseudomonas aeruginosa is mediated by the novel two-component regulatory system ParR-ParS. Antimicrob Agents Chemother (2010) 1.74
Synergistic interactions between mammalian antimicrobial defense peptides. Antimicrob Agents Chemother (2001) 1.56
Antimicrobial peptide therapeutics for cystic fibrosis. Antimicrob Agents Chemother (2005) 1.44
A two-component regulatory system interconnects resistance to polymyxins, aminoglycosides, fluoroquinolones, and β-lactams in Pseudomonas aeruginosa. Antimicrob Agents Chemother (2010) 1.28
Peptide design for antimicrobial and immunomodulatory applications. Biopolymers (2013) 0.99
Antibacterial studies of cationic polymers with alternating, random, and uniform backbones. ACS Chem Biol (2011) 0.97
Solution structure and interaction of the antimicrobial polyphemusins with lipid membranes. Biochemistry (2005) 0.95
Designed beta-boomerang antiendotoxic and antimicrobial peptides: structures and activities in lipopolysaccharide. J Biol Chem (2009) 0.94
Structures of β-hairpin antimicrobial protegrin peptides in lipopolysaccharide membranes: mechanism of gram selectivity obtained from solid-state nuclear magnetic resonance. Biochemistry (2011) 0.88
Using near-infrared spectroscopy to resolve the species, gender, age, and the presence of Wolbachia infection in laboratory-reared Drosophila. G3 (Bethesda) (2012) 0.86
Interaction of antimicrobial peptide temporin L with lipopolysaccharide in vitro and in experimental rat models of septic shock caused by gram-negative bacteria. Antimicrob Agents Chemother (2006) 0.86
The antimicrobial peptide polyphemusin localizes to the cytoplasm of Escherichia coli following treatment. Antimicrob Agents Chemother (2006) 0.86
Peptides and Peptidomimetics for Antimicrobial Drug Design. Pharmaceuticals (Basel) (2015) 0.85
Synergistic effect of membrane-active peptides polymyxin B and gramicidin S on multidrug-resistant strains and biofilms of Pseudomonas aeruginosa. Antimicrob Agents Chemother (2015) 0.82
A lipoprotein/β-barrel complex monitors lipopolysaccharide integrity transducing information across the outer membrane. Elife (2016) 0.81
Implicit Membrane Investigation of the Stability of Antimicrobial Peptide β-Barrels and Arcs. J Membr Biol (2014) 0.79
Comparison between the behavior of different hydrophobic peptides allowing membrane anchoring of proteins. Adv Colloid Interface Sci (2014) 0.75
Antibacterial activity and mechanism of Ag/ZnO nanocomposite against anaerobic oral pathogen Streptococcus mutans. J Mater Sci Mater Med (2017) 0.75
Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen. Nature (2000) 32.30
Room-temperature ultraviolet nanowire nanolasers. Science (2001) 9.79
Outer membrane of Pseudomonas aeruginosa: heat- 2-mercaptoethanol-modifiable proteins. J Bacteriol (1979) 9.28
Procedure for isolation of bacterial lipopolysaccharides from both smooth and rough Pseudomonas aeruginosa and Salmonella typhimurium strains. J Bacteriol (1983) 8.19
Outer membranes of gram-negative bacteria. XIX. Isolation from Pseudomonas aeruginosa PAO1 and use in reconstitution and definition of the permeability barrier. J Bacteriol (1978) 7.66
Vesicles of variable sizes produced by a rapid extrusion procedure. Biochim Biophys Acta (1986) 7.07
Pseudomonas aeruginosa isolates from patients with cystic fibrosis: a class of serum-sensitive, nontypable strains deficient in lipopolysaccharide O side chains. Infect Immun (1983) 6.24
Outer membrane permeability in Pseudomonas aeruginosa: comparison of a wild-type with an antibiotic-supersusceptible mutant. Antimicrob Agents Chemother (1982) 4.98
Outer membrane protein H1 of Pseudomonas aeruginosa: involvement in adaptive and mutational resistance to ethylenediaminetetraacetate, polymyxin B, and gentamicin. J Bacteriol (1980) 4.93
Con--mutants: class of mutants in Escherichia coli K-12 lacking a major cell wall protein and defective in conjugation and adsorption of a bacteriophage. J Bacteriol (1974) 4.63
Iron transport of Escherichia coli K-12: involvement of the colicin B receptor and of a citrate-inducible protein. J Bacteriol (1976) 4.35
Alterations in outer membrane permeability. Annu Rev Microbiol (1984) 4.22
Involvement of the outer membrane in gentamicin and streptomycin uptake and killing in Pseudomonas aeruginosa. Antimicrob Agents Chemother (1981) 3.95
Mechanism of interaction of different classes of cationic antimicrobial peptides with planar bilayers and with the cytoplasmic membrane of Escherichia coli. Biochemistry (1999) 3.88
Identification of the protein producing transmembrane diffusion pores in the outer membrane of Pseudomonas aeruginosa PA01. Biochim Biophys Acta (1979) 3.70
Properties of the large ion-permeable pores formed from protein F of Pseudomonas aeruginosa in lipid bilayer membranes. Biochim Biophys Acta (1981) 3.65
Functional organization of the outer membrane of escherichia coli: phage and colicin receptors as components of iron uptake systems. J Supramol Struct (1976) 3.53
The role of antimicrobial peptides in animal defenses. Proc Natl Acad Sci U S A (2000) 3.52
Use of the fluorescent probe 1-N-phenylnaphthylamine to study the interactions of aminoglycoside antibiotics with the outer membrane of Pseudomonas aeruginosa. Antimicrob Agents Chemother (1984) 3.19
Comparative genomics of Helicobacter pylori: analysis of the outer membrane protein families. Infect Immun (2000) 3.13
Interaction of the cyclic antimicrobial cationic peptide bactenecin with the outer and cytoplasmic membrane. J Biol Chem (1999) 3.07
Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria. Antimicrob Agents Chemother (2000) 3.06
Pseudomonas aeruginosa outer membrane permeability: isolation of a porin protein F-deficient mutant. J Bacteriol (1983) 2.98
Bacteriophage resistance in Escherichia coli K-12: general pattern of resistance. J Bacteriol (1975) 2.94
Ion selectivity of gram-negative bacterial porins. J Bacteriol (1985) 2.87
Multidrug resistance (MDR) in cancer. Mechanisms, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs. Eur J Pharm Sci (2000) 2.81
Aminoglycoside uptake and mode of action--with special reference to streptomycin and gentamicin. I. Antagonists and mutants. J Antimicrob Chemother (1981) 2.78
Interaction of polycationic antibiotics with Pseudomonas aeruginosa lipopolysaccharide and lipid A studied by using dansyl-polymyxin. Antimicrob Agents Chemother (1986) 2.74
Outer membrane protein P of Pseudomonas aeruginosa: regulation by phosphate deficiency and formation of small anion-specific channels in lipid bilayer membranes. J Bacteriol (1982) 2.73
Chemical and chromatographic analysis of lipopolysaccharide from an antibiotic-supersusceptible mutant of Pseudomonas aeruginosa. Antimicrob Agents Chemother (1982) 2.64
Iron transport in Escherichia coli K-12. 2,3-Dihydroxybenzoate-promoted iron uptake. Arch Microbiol (1977) 2.62
Monoclonal antibodies against Pseudomonas aeruginosa outer membrane antigens: isolation and characterization. Infect Immun (1982) 2.61
Impact of point-of-care testing on patients' length of stay in a large emergency department. Clin Chem (1996) 2.59
Mode of action of the antimicrobial peptide indolicidin. J Biol Chem (1996) 2.57
Surface localization of Pseudomonas aeruginosa outer membrane porin protein F by using monoclonal antibodies. Infect Immun (1983) 2.51
Compounds which increase the permeability of the Pseudomonas aeruginosa outer membrane. Antimicrob Agents Chemother (1984) 2.37
Heterogeneity of lipopolysaccharides from Pseudomonas aeruginosa: analysis of lipopolysaccharide chain length. J Bacteriol (1988) 2.35
Outer membrane proteins of Pseudomonas aeruginosa serotype strains. J Infect Dis (1982) 2.32
Aminoglycoside uptake and mode of action-with special reference to streptomycin and gentamicin. II. Effects of aminoglycosides on cells. J Antimicrob Chemother (1981) 2.29
An IgM lambda antibody to Escherichia coli produces false-positive results in multiple immunometric assays. Clin Chem (2000) 2.28
Role of Pseudomonas aeruginosa PhoP-phoQ in resistance to antimicrobial cationic peptides and aminoglycosides. Microbiology (2000) 2.21
PhoP-PhoQ homologues in Pseudomonas aeruginosa regulate expression of the outer-membrane protein OprH and polymyxin B resistance. Mol Microbiol (1999) 2.19
Interaction of cationic antimicrobial peptides with model membranes. J Biol Chem (2001) 2.16
Expression in Escherichia coli and function of Pseudomonas aeruginosa outer membrane porin protein F. J Bacteriol (1986) 2.15
Antiendotoxin activity of cationic peptide antimicrobial agents. Infect Immun (1996) 2.13
Combinatorial signaling in the specification of unique cell fates. Cell (2000) 2.13
Clinical utility of biochemical analysis of cerebrospinal fluid. Clin Chem (1995) 2.11
A role for Cdk2 kinase in negatively regulating DNA replication during S phase of the cell cycle. J Cell Biol (1997) 2.09
Pseudomonas aeruginosa outer membrane: peptidoglycan-associated proteins. J Bacteriol (1981) 2.06
Role of porins in outer membrane permeability. J Bacteriol (1987) 2.06
Solute distributions and trapping efficiencies observed in freeze-thawed multilamellar vesicles. Biochim Biophys Acta (1985) 2.05
The rare outer membrane protein, OmpL1, of pathogenic Leptospira species is a heat-modifiable porin. Infect Immun (1995) 2.03
Stat recruitment by tyrosine-phosphorylated cytokine receptors: an ordered reversible affinity-driven process. Immunity (1995) 2.00
Interactions of bacterial cationic peptide antibiotics with outer and cytoplasmic membranes of Pseudomonas aeruginosa. Antimicrob Agents Chemother (2000) 1.99
Salmonella typhimurium infection and lipopolysaccharide stimulation induce similar changes in macrophage gene expression. J Immunol (2000) 1.93
Cationic antimicrobial peptides and their multifunctional role in the immune system. Crit Rev Immunol (2000) 1.93
Interaction of macrophage cationic proteins with the outer membrane of Pseudomonas aeruginosa. Infect Immun (1988) 1.92
Binding of polycationic antibiotics and polyamines to lipopolysaccharides of Pseudomonas aeruginosa. J Bacteriol (1985) 1.90
PhyloBLAST: facilitating phylogenetic analysis of BLAST results. Bioinformatics (2001) 1.89
Involvement of outer membrane of Pseudomonas cepacia in aminoglycoside and polymyxin resistance. Antimicrob Agents Chemother (1986) 1.87
Lipopolysaccharide-deficient, bacteriophage-resistant mutants of Escherichia coli K-12. J Bacteriol (1976) 1.86
Evidence for two distinct mechanisms of resistance to polymyxin B in Pseudomonas aeruginosa. Antimicrob Agents Chemother (1984) 1.81
Pseudomonas aeruginosa outer membrane protein F: structural role and relationship to the Escherichia coli OmpA protein. J Bacteriol (1989) 1.81
Salt-resistant alpha-helical cationic antimicrobial peptides. Antimicrob Agents Chemother (1999) 1.78
Monoclonal antibodies specific for Escherichia coli J5 lipopolysaccharide: cross-reaction with other gram-negative bacterial species. Infect Immun (1984) 1.77
Negative regulation of the Pseudomonas aeruginosa outer membrane porin OprD selective for imipenem and basic amino acids. Antimicrob Agents Chemother (1999) 1.76
The colicin I receptor of Escherichia coli K-12 has a role in enterochelin-mediated iron transport. FEBS Lett (1976) 1.68
Isolation of the outer membranes from Treponema pallidum and Treponema vincentii. J Bacteriol (1994) 1.67
Isolation of the outer membrane and characterization of the major outer membrane protein from Spirochaeta aurantia. J Bacteriol (1987) 1.67
Pore-forming properties of the major 53-kilodalton surface antigen from the outer sheath of Treponema denticola. Infect Immun (1993) 1.66
Quantitation and identification of antibodies to outer-membrane proteins of Pseudomonas aeruginosa in sera of patients with cystic fibrosis. J Infect Dis (1984) 1.62
Dissociation of antimicrobial and hemolytic activities in cyclic peptide diastereomers by systematic alterations in amphipathicity. J Biol Chem (1999) 1.61
Liposome encapsulated vincristine: preclinical toxicologic and pharmacologic comparison with free vincristine and empty liposomes in mice, rats and dogs. Anticancer Drugs (1994) 1.59
Dyspepsia and irritable bowel syndrome in China: a population-based endoscopy study of prevalence and impact. Aliment Pharmacol Ther (2010) 1.59
Characterization of two surface-localized antigenic sites on porin protein F of Pseudomonas aeruginosa. Can J Microbiol (1985) 1.58
Helicobacter pylori uptake and efflux: basis for intrinsic susceptibility to antibiotics in vitro. Antimicrob Agents Chemother (2000) 1.58
Structure of the bovine antimicrobial peptide indolicidin bound to dodecylphosphocholine and sodium dodecyl sulfate micelles. Biochemistry (2000) 1.57
Alteration of susceptibility to EDTA, polymyxin B and gentamicin in Pseudomonas aeruginosa by divalent cation regulation of outer membrane protein H1. J Gen Microbiol (1983) 1.56
Synergistic interactions between mammalian antimicrobial defense peptides. Antimicrob Agents Chemother (2001) 1.56
Controlling the physical behavior and biological performance of liposome formulations through use of surface grafted poly(ethylene glycol). Biosci Rep (2002) 1.53
Isolation and characterization of a family of porin proteins from Helicobacter pylori. Infect Immun (1995) 1.52
Uptake of adriamycin into large unilamellar vesicles in response to a pH gradient. Biochim Biophys Acta (1986) 1.52
Cutting edge: cationic antimicrobial peptides block the binding of lipopolysaccharide (LPS) to LPS binding protein. J Immunol (2000) 1.51
Improvement of outer membrane-permeabilizing and lipopolysaccharide-binding activities of an antimicrobial cationic peptide by C-terminal modification. Antimicrob Agents Chemother (1994) 1.51
Modulation of structure and antibacterial and hemolytic activity by ring size in cyclic gramicidin S analogs. J Biol Chem (1996) 1.50
Influence of proline residues on the antibacterial and synergistic activities of alpha-helical peptides. Biochemistry (1999) 1.48
Mitogenic effects of purified outer membrane proteins from Pseudomonas aeruginosa. Infect Immun (1980) 1.48
The benefits of a hospital based community services liaison pharmacist. Pharm World Sci (2000) 1.48
Sequencing solution: use volunteer annotators organized via Internet. Nature (2000) 1.46
Spontaneous secretion of IgG subclasses by intestinal mononuclear cells: differences between ulcerative colitis, Crohn's disease, and controls. Clin Exp Immunol (1986) 1.46
The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signals. EMBO J (1996) 1.45
Demonstration and chemical modification of a specific phosphate binding site in the phosphate-starvation-inducible outer membrane porin protein P of Pseudomonas aeruginosa. Biochim Biophys Acta (1986) 1.42
Improved activity of a synthetic indolicidin analog. Antimicrob Agents Chemother (1997) 1.41
Purification, characterization, and localization of linamarase in cassava. Plant Physiol (1990) 1.41