Published in Arthritis Res on October 26, 1999
Classification of rheumatoid arthritis status with candidate gene and genome-wide single-nucleotide polymorphisms using random forests. BMC Proc (2007) 1.24
The polymorphisms of Tim-1 promoter region are associated with rheumatoid arthritis in a Korean population. Immunogenetics (2004) 1.03
What precedes development of rheumatoid arthritis? Ann Rheum Dis (2004) 1.01
Proteoglycan-induced arthritis and recombinant human proteoglycan aggrecan G1 domain-induced arthritis in BALB/c mice resembling two subtypes of rheumatoid arthritis. Arthritis Rheum (2011) 0.99
Association of MHC and rheumatoid arthritis. HLA-DR4 and rheumatoid arthritis: studies in mice and men. Arthritis Res (2000) 0.92
Using twin studies to label disease as genetic or environmental is inappropriate. BMJ (2002) 0.91
Association of TBX21 polymorphisms in a Korean population with rheumatoid arthritis. Exp Mol Med (2009) 0.88
Indian herbal medicines: possible potent therapeutic agents for rheumatoid arthritis. J Clin Biochem Nutr (2007) 0.88
Polymorphisms of COTL1 gene identified by proteomic approach and their association with autoimmune disorders. Exp Mol Med (2009) 0.88
BALB/c mice genetically susceptible to proteoglycan-induced arthritis and spondylitis show colony-dependent differences in disease penetrance. Arthritis Res Ther (2009) 0.86
Identification of correlated genetic variants jointly associated with rheumatoid arthritis using ridge regression. BMC Proc (2009) 0.84
A powerful approach for association analysis incorporating imprinting effects. Bioinformatics (2011) 0.84
Genetic and molecular basis of quantitative trait loci of arthritis in rat: genes and polymorphisms. J Immunol (2008) 0.84
Toll-like receptors are potential therapeutic targets in rheumatoid arthritis. World J Biol Chem (2011) 0.78
Comparison of genome-wide single-nucleotide polymorphism linkage analyses in Caucasian and Hispanic NARAC families. BMC Proc (2007) 0.77
Distribution of candidate genes for experimentally induced arthritis in rats. BMC Genomics (2010) 0.77
Joint-specific and systemic autoreactivity in the development of inflammatory arthritis. Arthritis Res (1999) 0.75
The North Shore-Long Island Jewish Research Institute. Mol Med (2003) 0.75
The Association of the GABRP Polymorphisms with Systemic Lupus Erythematosus. J Immunol Res (2015) 0.75
The future of genetic studies of complex human diseases. Science (1996) 64.76
Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nat Genet (1999) 24.24
Linkage strategies for genetically complex traits. I. Multilocus models. Am J Hum Genet (1990) 19.91
Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis. Nat Genet (1999) 17.09
The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum (1987) 14.21
DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene. Nat Genet (1998) 11.70
Expression profiling using cDNA microarrays. Nat Genet (1999) 11.58
Association of the B-cell alloantigen DRw4 with rheumatoid arthritis. N Engl J Med (1978) 7.97
Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc Natl Acad Sci U S A (1997) 6.99
The power of association studies to detect the contribution of candidate genetic loci to variation in complex traits. Genome Res (1999) 5.03
Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes. Cell (1999) 5.01
Who's afraid of epistasis? Nat Genet (1996) 4.24
Genetic analysis of autoimmune disease. Cell (1996) 3.87
Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus. Nat Genet (1997) 3.62
The influence of HLA-DRB1 genes on disease severity in rheumatoid arthritis. Ann Intern Med (1992) 3.36
Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases. Proc Natl Acad Sci U S A (1998) 3.35
Twin concordance rates for rheumatoid arthritis: results from a nationwide study. Br J Rheumatol (1993) 3.33
The genetic basis for the association of the 8.1 ancestral haplotype (A1, B8, DR3) with multiple immunopathological diseases. Immunol Rev (1999) 3.21
New susceptibility locus for rheumatoid arthritis suggested by a genome-wide linkage study. Proc Natl Acad Sci U S A (1998) 3.14
The genetics revolution and the assault on rheumatoid arthritis. Arthritis Rheum (1999) 2.92
Blood transfusion, smoking, and obesity as risk factors for the development of rheumatoid arthritis: results from a primary care-based incident case-control study in Norfolk, England. Arthritis Rheum (1997) 2.90
Monoallelic expression of the interleukin-2 locus. Science (1998) 2.58
Polymorphic haplotypes of the interleukin-10 5' flanking region determine variable interleukin-10 transcription and are associated with particular phenotypes of juvenile rheumatoid arthritis. Arthritis Rheum (1999) 2.39
The female X-inactivation mosaic in systemic lupus erythematosus. Immunol Today (1998) 2.33
It's raining SNPs, hallelujah? Nat Genet (1998) 2.30
Dominant-negative p53 mutations in rheumatoid arthritis. Arthritis Rheum (1999) 2.18
RNA and the epigenetic regulation of X chromosome inactivation. Cell (1998) 2.10
HLA heterozygosity contributes to susceptibility to rheumatoid arthritis. Am J Hum Genet (1992) 2.03
Familial clustering of rheumatoid arthritis with other autoimmune diseases. Hum Genet (1998) 1.99
Regulation of IL-4 expression by activation of individual alleles. Immunity (1998) 1.84
CTLA4 alanine-17 confers genetic susceptibility to Graves' disease and to type 1 diabetes mellitus. J Clin Endocrinol Metab (1997) 1.78
Monoallelic expression: 'there can only be one'. Trends Genet (1998) 1.72
Quantifying the exact role of HLA-DRB1 alleles in susceptibility to inflammatory polyarthritis: results from a large, population-based study. Arthritis Rheum (1999) 1.61
Commitment to X inactivation precedes the twinning event in monochorionic MZ twins. Am J Hum Genet (1998) 1.61
Haplotype associated with low interleukin-10 production in patients with severe asthma. Lancet (1998) 1.59
Epistatic modifiers of autoimmunity in a murine model of lupus nephritis. Immunity (1999) 1.59
HLA-DR4 and HLA-DR10 motifs that carry susceptibility to rheumatoid arthritis bind 70-kD heat shock proteins. Nat Med (1996) 1.54
Major histocompatibility complex-directed susceptibility to rheumatoid arthritis. Adv Immunol (1998) 1.52
A male-female bias in type 1 diabetes and linkage to chromosome Xp in MHC HLA-DR3-positive patients. Nat Genet (1998) 1.50
Interleukin-1beta, interleukin-1 receptor antagonist, interleukin-4, and interleukin-10 gene polymorphisms: relationship to occurrence and severity of rheumatoid arthritis. Arthritis Rheum (1999) 1.50
Could HLA-DRB1 be the protective locus in rheumatoid arthritis? Immunol Today (1995) 1.38
Specific HLA-DR4-associated histocompatibility molecules characterize patients with seropositive juvenile rheumatoid arthritis. J Clin Invest (1984) 1.37
Direct genetic analysis by matrix-assisted laser desorption/ionization mass spectrometry. Proc Natl Acad Sci U S A (1999) 1.30
The hereditary periodic fever syndromes: molecular analysis of a new family of inflammatory diseases. Hum Mol Genet (1998) 1.30
Genetic interrelationship between insulin-dependent diabetes mellitus, the autoimmune thyroid diseases, and rheumatoid arthritis. Am J Hum Genet (1986) 1.28
Genetic variability in the tumor necrosis factor-lymphotoxin region influences susceptibility to rheumatoid arthritis. Am J Hum Genet (1996) 1.23
Familial autoimmunity in pedigrees of idiopathic inflammatory myopathy patients suggests common genetic risk factors for many autoimmune diseases. Arthritis Rheum (1998) 1.20
The joint alignment and motion scale: a simple measure of joint deformity in patients with rheumatoid arthritis. J Rheumatol (1987) 1.14
Mechanisms underlying the formation of the T cell receptor repertoire in rheumatoid arthritis. Immunity (1995) 1.10
Investigation of the HLA component involved in rheumatoid arthritis (RA) by using the marker association-segregation chi-square (MASC) method: rejection of the unifying-shared-epitope hypothesis. Am J Hum Genet (1993) 1.07
IL-10 gene promoter polymorphisms in rheumatoid arthritis. Scand J Rheumatol (1998) 1.05
Discordance for autoimmunity in monozygotic twins. Are "identical" twins really identical? Arthritis Rheum (1993) 1.04
Twin studies in rheumatic diseases. Semin Arthritis Rheum (1994) 1.02
Association of polymorphism in glutathione S-transferase loci with susceptibility and outcome in rheumatoid arthritis: comparison with the shared epitope. Ann Rheum Dis (1999) 1.01
CTLA4 polymorphisms in Spanish patients with rheumatoid arthritis. Tissue Antigens (1999) 1.00
Genetic bias in immune responses to a cassette shared by different microorganisms in patients with rheumatoid arthritis. J Clin Invest (1997) 0.99
CTLA4 codon 17 dimorphism in patients with rheumatoid arthritis. Tissue Antigens (1998) 0.98
The North American Rheumatoid Arthritis Consortium--bringing genetic analysis to bear on disease susceptibility, severity, and outcome. Arthritis Care Res (1998) 0.98
Genomic imprinting: mechanism and role in human pathology. Am J Pathol (1994) 0.97
Sex influences on the penetrance of HLA shared-epitope genotypes for rheumatoid arthritis. Am J Hum Genet (1996) 0.97
Binding energetics of T-cell receptors: correlation with immunological consequences. Immunol Today (1999) 0.96
CTLA-4 gene polymorphism confers susceptibility to insulin-dependent diabetes mellitus (IDDM) independently from age and from other genetic or immune disease markers. The Belgian Diabetes Registry. Clin Exp Immunol (1997) 0.94
Tumor necrosis factor a microsatellite polymorphism is associated with rheumatoid arthritis severity through an interaction with the HLA-DRB1 shared epitope. Arthritis Rheum (1999) 0.94
The Arthritis and Rheumatism Council's national family material repository. Br J Rheumatol (1993) 0.92
The role of T cell receptor beta chain genes in susceptibility to rheumatoid arthritis. Arthritis Rheum (1995) 0.90
Linkage and association studies of the natural resistance associated macrophage protein 1 (NRAMP1) locus in rheumatoid arthritis. J Rheumatol (1997) 0.86
Molecular epidemiology of autoimmune thyroid disease. Gac Med Mex (1997) 0.84
Association of rheumatoid arthritis with an amino acid allelic variation of the T cell receptor. Arthritis Rheum (1997) 0.79
Synergy between T cell receptor beta gene polymorphism and HLA-DR4 in susceptibility to rheumatoid arthritis. Arthritis Rheum (1996) 0.79
Snipping "SNPs": a new tool for mining gene variations. J Natl Cancer Inst (1999) 0.78
Corticotropin releasing hormone promoter region polymorphisms in rheumatoid arthritis. J Rheumatol (1997) 0.78
Investigation of candidate disease susceptibility genes in rheumatoid arthritis: principles and strategies. J Rheumatol (1997) 0.77
Analysis of T cell receptor V alpha polymorphisms in rheumatoid arthritis. Ann Rheum Dis (1998) 0.77
Increased X-inactivation skewing in SLE? Immunol Today (1999) 0.77
Inheritance of the shared epitope and long-term outcomes of rheumatoid arthritis among community-based Caucasian females. Genet Epidemiol (1998) 0.77