Published in Clin Pharmacol Ther on November 01, 2000
Pharmacodynamics of PEG-IFN-alpha-2a in HIV/HCV co-infected patients: implications for treatment outcomes. J Hepatol (2010) 1.78
A perspective on modelling hepatitis C virus infection. J Viral Hepat (2010) 1.67
Modeling HCV kinetics under therapy using PK and PD information. Expert Opin Drug Metab Toxicol (2009) 1.22
Critical issues in the treatment of hepatitis C virus infection in methadone maintenance patients. Addiction (2008) 1.20
Racial differences in the evaluation and treatment of hepatitis C among veterans: a retrospective cohort study. Am J Public Health (2008) 1.19
Cyclic changes in gene expression induced by Peg-interferon alfa-2b plus ribavirin in peripheral blood monocytes (PBMC) of hepatitis C patients during the first 10 weeks of treatment. J Transl Med (2008) 1.11
Emerging synthetic approaches for protein-polymer conjugations. Chem Commun (Camb) (2011) 1.10
Pegylated interferons alpha2a and alpha2b in the treatment of chronic hepatitis C. Nat Rev Gastroenterol Hepatol (2010) 1.08
Treatment of hepatitis C virus infection with interferon and small molecule direct antivirals: viral kinetics and modeling. Crit Rev Immunol (2010) 1.02
Protein-polymer conjugates: synthetic approaches by controlled radical polymerizations and interesting applications. Curr Opin Chem Biol (2010) 0.99
Stable high volumetric production of glycosylated human recombinant IFNalpha2b in HEK293 cells. BMC Biotechnol (2008) 0.97
Hepatitis C virus infection and mixed cryoglobulinemia. Clin Dev Immunol (2012) 0.94
Cell-based hepatitis C virus infection fluorescence resonance energy transfer (FRET) assay for antiviral compound screening. Curr Protoc Microbiol (2010) 0.94
Pegylated interferon-alpha plus taurine in treatment of rat liver fibrosis. World J Gastroenterol (2007) 0.93
Effect of peginterferon beta-1a on MRI measures and achieving no evidence of disease activity: results from a randomized controlled trial in relapsing-remitting multiple sclerosis. BMC Neurol (2014) 0.91
Pharmacokinetic/pharmacodynamic analysis of adjuvant pegylated interferon α-2b in patients with resected high-risk melanoma. Cancer Chemother Pharmacol (2010) 0.91
Managing pediatric hepatitis C: current and emerging treatment options. Ther Clin Risk Manag (2009) 0.90
Severe interstitial pneumonitis secondary to pegylated interferon alpha-2b and ribavirin treatment of hepatitis C infection. Dig Dis Sci (2005) 0.90
Nanomedicines in the treatment of hepatitis C virus infection in Asian patients: optimizing use of peginterferon alfa. Int J Nanomedicine (2014) 0.89
PEGylated Adenoviruses: From Mice to Monkeys. Viruses (2010) 0.89
Effects of a 24-week course of interferon-alpha therapy after curative treatment of hepatitis C virus-associated hepatocellular carcinoma. World J Gastroenterol (2007) 0.87
Hepatitis C virus experimental model systems and antiviral drug research. Virol Sin (2010) 0.87
Managing chronic hepatitis C in the difficult-to-treat patient. Liver Int (2007) 0.84
Saturable human neopterin response to interferon-α assessed by a pharmacokinetic-pharmacodynamic model. J Transl Med (2013) 0.84
Pharmacokinetic and pharmacodynamic comparison of two "pegylated" interferon alpha-2 formulations in healthy male volunteers: a randomized, crossover, double-blind study. BMC Pharmacol (2010) 0.83
New developments in the treatment of hepatitis C. Gut (2003) 0.82
Combination therapy of intra-arterial 5-fluorouracil and systemic pegylated interferon α-2b for advanced hepatocellular carcinoma. Int J Clin Oncol (2010) 0.82
Single-dose pharmacokinetics and tolerability of pegylated interferon-alpha2b in young and elderly healthy subjects. Br J Clin Pharmacol (2003) 0.81
Identification of hepatitis C virus inhibitors targeting different aspects of infection using a cell-based assay. Antimicrob Agents Chemother (2012) 0.81
Convenient biological assay for polyethylene glycol-interferons in patients with hepatitis C. Antimicrob Agents Chemother (2004) 0.81
A single N-acetylgalactosamine residue at threonine 106 modifies the dynamics and structure of interferon α2a around the glycosylation site. J Biol Chem (2012) 0.80
SASLT practice guidelines: management of hepatitis C virus infection. Saudi J Gastroenterol (2012) 0.80
Mutations in the interferon sensitivity determining region and virological response to combination therapy with pegylated-interferon alpha 2b plus ribavirin in patients with chronic hepatitis C-1b infection. J Gastroenterol (2010) 0.80
Pharmacokinetics and pharmacodynamics of peginterferon and ribavirin: implications for clinical efficacy in the treatment of chronic hepatitis C. Gastroenterol Clin North Am (2010) 0.79
Relevance of the Core 70 and IL-28B polymorphism and response-guided therapy of peginterferon alfa-2a ± ribavirin for chronic hepatitis C of Genotype 1b: a multicenter randomized trial, ReGIT-J study. J Gastroenterol (2013) 0.79
Influence of IL28B polymorphisms on response to a lower-than-standard dose peg-IFN-α 2a for genotype 3 chronic hepatitis C in HIV-coinfected patients. PLoS One (2012) 0.79
Population pharmacokinetics of peginterferon alfa-2b in pediatric patients with chronic hepatitis C. Eur J Clin Pharmacol (2013) 0.79
PEGylated interferon beta-1a in the treatment of multiple sclerosis - an update. Biologics (2013) 0.78
Cost-effectiveness analysis of adding low dose ribavirin to peginterferon alfa-2a for treatment of chronic hepatitis C infected thalassemia major patients in iran. Hepat Mon (2013) 0.78
Chronic Hepatitis C. Curr Treat Options Gastroenterol (2001) 0.78
Viral hepatitis in hemodialysis: An update. J Transl Int Med (2015) 0.78
Nanomedicines in the treatment of patients with hepatitis C co-infected with HIV--focus on pegylated interferon-alpha. Int J Nanomedicine (2006) 0.77
Dose selection and population pharmacokinetics of PEG-Intron in patients with chronic myelogenous leukaemia. Br J Clin Pharmacol (2006) 0.77
Bioimaging of Hyaluronate-Interferon α Conjugates Using a Non-Interfering Zwitterionic Fluorophore. Biomacromolecules (2015) 0.76
Chronic Hepatitis B and C--current treatment and future therapeutic prospects. Wien Med Wochenschr (2006) 0.76
HBV and HCV therapy. Viruses (2009) 0.76
The treatment response of chronically hepatitis C virus-infected patients depends on interferon concentration but not on interferon gene expression in peripheral blood mononuclear cells. Antimicrob Agents Chemother (2011) 0.75
Combination immunotherapy for high-risk resected and metastatic melanoma patients. Ochsner J (2014) 0.75
Feasibility of Pegylated Interferon in Children and Young Adults With Resected High-Risk Melanoma. Pediatr Blood Cancer (2016) 0.75
Kinetic and dynamic computational model-based characterization of new proteins in mice: application to interferon alpha linked to apolipoprotein A-I. PLoS One (2012) 0.75
A pharmacokinetic and pharmacodynamic comparison of a novel pegylated recombinant consensus interferon-α variant with peginterferon-α-2a in healthy subjects. Br J Clin Pharmacol (2015) 0.75
Adjuvant pegylated interferon α-2b therapy for melanoma. Oncol Lett (2010) 0.75
Pegylated interferon alpha-2b as adjuvant treatment of Stage III malignant melanoma: an evidence-based review. Core Evid (2010) 0.75
Lack of Efficacy of Pegylated Interferon Monotherapy for Hepatitis C in Patients With End-Stage Renal Disease on Dialysis. Gastroenterol Hepatol (N Y) (2006) 0.75
Anti-hepatitis C virus drugs and kidney. World J Hepatol (2016) 0.75
Pharmacokinetics of PEGylated recombinant human endostatin (M2ES) in rats. Acta Pharmacol Sin (2015) 0.75
Update of research and management of hepatitis B. J Gastroenterol (2006) 0.75
Avoiding recomputation in linkage analysis. Hum Hered (1994) 8.39
A receptor in pituitary and hypothalamus that functions in growth hormone release. Science (1996) 5.45
Current estimates of blindness in India. Br J Ophthalmol (2005) 3.49
Cellular receptor for 125I-labeled tumor necrosis factor: specific binding, affinity labeling, and relationship to sensitivity. Proc Natl Acad Sci U S A (1985) 2.92
Traumatic grief as a risk factor for mental and physical morbidity. Am J Psychiatry (1997) 2.80
Surgical complication outcome (SCOUT) score: a new method to evaluate quality of care in vascular surgery. J Vasc Surg (1997) 2.67
Emissions of gaseous and particulate pollutants in a port and harbour region in India. Environ Monit Assess (2002) 2.63
Antibodies to purified insulin receptor have insulin-like activity. Science (1978) 2.58
Somatomedin-C stimulates the phosphorylation of the beta-subunit of its own receptor. J Biol Chem (1983) 2.55
Monoclonal antibodies to receptors for insulin and somatomedin-C. J Biol Chem (1983) 2.53
Statistical analyses of coastal water quality for a port and harbour region in India. Environ Monit Assess (2005) 2.46
Comparison of open and laparoscopic live donor nephrectomy. Ann Surg (1997) 2.43
Six-year prospective multicenter randomized comparison of autologous saphenous vein and expanded polytetrafluoroethylene grafts in infrainguinal arterial reconstructions. J Vasc Surg (1986) 2.41
Computer-enhanced "robotic" cardiac surgery: experience in 148 patients. J Thorac Cardiovasc Surg (2001) 2.40
Characterization of soluble hepatitis C virus RNA-dependent RNA polymerase expressed in Escherichia coli. J Virol (1999) 2.37
Phorbol esters stimulate the phosphorylation of receptors for insulin and somatomedin C. Proc Natl Acad Sci U S A (1983) 2.30
Insulin receptor: covalent labeling and identification of subunits. Proc Natl Acad Sci U S A (1979) 2.24
Optimization of desflurane administration in morbidly obese patients: a comparison with sevoflurane using an 'inhalation bolus' technique. Br J Anaesth (2003) 2.17
Synergistic action of metolazone with "loop" diuretics. Br Med J (Clin Res Ed) (1981) 2.16
Association of phorbol ester-induced hyperphosphorylation and reversible regulation of transferrin membrane receptors in HL60 cells. Proc Natl Acad Sci U S A (1984) 2.14
Biosynthesis of aflatoxins. Bacteriol Rev (1977) 2.11
Fluorescent labeling of hormone receptors in viable cells: preparation and properties of highly fluorescent derivatives of epidermal growth factor and insulin. Proc Natl Acad Sci U S A (1978) 2.03
Ice-shelf melting around Antarctica. Science (2013) 1.98
Unique clinical characteristics of primary hyperparathyroidism in India. Br J Surg (2001) 1.88
A comparison of recipient renal outcomes with laparoscopic versus open live donor nephrectomy. Transplantation (1999) 1.88
NH3 gas sensing properties of nanocrystalline ZnO based thick films. Anal Chim Acta (2006) 1.86
Recombinant human monoclonal antibody IgG1b12 neutralizes diverse human immunodeficiency virus type 1 primary isolates. AIDS Res Hum Retroviruses (1997) 1.84
Causes and temporal trends of blindness and severe visual impairment in children in schools for the blind in North India. Br J Ophthalmol (2003) 1.83
Complicated grief as a disorder distinct from bereavement-related depression and anxiety: a replication study. Am J Psychiatry (1996) 1.81
Regulation of pri-microRNA BIC transcription and processing in Burkitt lymphoma. Oncogene (2006) 1.69
Protein-polysaccharides of pig laryngeal cartilage. Biochem J (1967) 1.68
Cloning and relative expression analysis of rat stromal cell derived factor-1 (SDF-1)1: SDF-1 alpha mRNA is selectively induced in rat model of myocardial infarction. Inflammation (2001) 1.67
The function of the soluble interleukin 6 (IL-6) receptor in vivo: sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6. J Exp Med (1996) 1.65
Remifentanil pharmacokinetics in obese versus lean patients. Anesthesiology (1998) 1.62
Surgery for adolescent hallux valgus. Acta Orthop Scand (1974) 1.61
The mobile receptor hypothesis and "cooperativity" of hormone binding. Application to insulin. Biochim Biophys Acta (1976) 1.60
Predicting outcome among intensive care unit patients using computerised trend analysis of daily Apache II scores corrected for organ system failure. Intensive Care Med (1988) 1.60
Status of pediatric eye care in India. Indian J Ophthalmol (2008) 1.59
The subunit structure of rat liver insulin receptor. Antibodies directed against the insulin-binding subunit. J Biol Chem (1980) 1.57
Purification and properties of the human placental insulin receptor. J Biol Chem (1981) 1.57
Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice. J Clin Invest (1989) 1.56
Efficacy of sutureless and glue free limbal conjunctival autograft for primary pterygium surgery. Nepal J Ophthalmol (2012) 1.56
Purification and properties of insulin receptors from rat liver membranes. Biochem Biophys Res Commun (1977) 1.54
Vitamin A deprivation results in reversible loss of hippocampal long-term synaptic plasticity. Proc Natl Acad Sci U S A (2001) 1.53
A potential complication associated with percutaneous tracheostomy with an endotracheal tube with a Murphy eye in situ. Anesthesiology (1998) 1.53
Nebulized magnesium for prevention of postoperative sore throat. Br J Anaesth (2012) 1.52
Differential concentration and time dependent effects of progesterone on kinase activity, hyperactivation and acrosome reaction in human spermatozoa. Int J Androl (2012) 1.52
Influence of intraoperative opioid on postoperative pain and pulmonary function after laparoscopic gastric banding: remifentanil TCI vs sufentanil TCI in morbid obesity. Br J Anaesth (2007) 1.51
Resting gated pool ejection fraction: a poor predictor of perioperative myocardial infarction in patients undergoing vascular surgery for infrainguinal bypass grafting. J Vasc Surg (1989) 1.50
Evidence from monoclonal antibody studies that insulin stimulates deoxyribonucleic acid synthesis through the type I somatomedin receptor. J Clin Endocrinol Metab (1985) 1.49
The significance of baseline serum alanine aminotransferase on pretreatment disease characteristics and response to antiviral therapy in chronic hepatitis C. Hepatology (2000) 1.49
Charcot's arthropathy of the shoulder following intraarticular corticosteroid injections. J Rheumatol (1993) 1.47
Insulin-like growth factor I receptor beta-subunit heterogeneity. Evidence for hybrid tetramers composed of insulin-like growth factor I and insulin receptor heterodimers. J Biol Chem (1989) 1.47
Culture and characterization of normal epithelium from cystoscopic biopsies of human bladder. In Vitro Cell Dev Biol Anim (1993) 1.47
A comparison of the effects on saliva output of oxybutynin chloride and tolterodine tartrate. Clin Ther (2001) 1.45
Work capacity and surgical output for cataract in the national capital region of Delhi and neighbouring districts of north India. Indian J Public Health (2009) 1.45
Part I. Analysis of data gaps pertaining to Salmonella enterica serotype Typhi infections in low and medium human development index countries, 1984-2005. Epidemiol Infect (2007) 1.44
Activation of tumor necrosis factor-alpha system in chronic hepatitis C virus infection. Dig Dis Sci (1997) 1.44
Interruption of critical aortoiliac collateral circulation during nonvascular operations: a cause of acute limb-threatening ischemia. J Vasc Surg (1990) 1.44
A dose-ranging study of pegylated interferon alfa-2b and ribavirin in chronic hepatitis C. The Hepatitis C Intervention Therapy Group. Hepatology (2000) 1.44
Quantitative aspects of hormone-receptor interactions of high affinity. Effect of receptor concentration and measurement of dissociation constants of labeled and unlabeled hormones. Biochim Biophys Acta (1975) 1.42
Safety of peripheral vascular surgery after recent acute myocardial infarction. J Vasc Surg (1990) 1.41
Monensin blocks the maturation of receptors for insulin and somatomedin C: identification of receptor precursors. Proc Natl Acad Sci U S A (1983) 1.40
Mitogen-activated protein kinase activation resulting from selective oncogene expression in NIH 3T3 and rat 1a cells. Proc Natl Acad Sci U S A (1992) 1.40
Pseudomonas aeruginosa outbreak associated with a contaminated blood-gas analyser in a neonatal intensive care unit. J Hosp Infect (1996) 1.40
Increased rates of donation with laparoscopic donor nephrectomy. Ann Surg (2000) 1.40
Modification in sucrose tolerance test with acarbose, guargum and their combination in patients with non-insulin dependent diabetes. J Assoc Physicians India (1993) 1.39
Cranial cystic epidermoid: report of two cases and review of the literature. Australas Radiol (1996) 1.39
Acute transient sialadenopathy associated with laryngeal mask airway. Anesth Analg (1998) 1.39
[Highly elevated alphafetoprotein and hepatic cirrhosis. It is not always hepatocarcinoma]. Presse Med (2001) 1.39
A phase II study of gemcitabine and cisplatin in chemotherapy-naive, unresectable gall bladder cancer. Br J Cancer (2004) 1.39
Laparoscopic versus open donor nephrectomy: comparing ureteral complications in the recipients and improving the laparoscopic technique. Transplantation (1999) 1.38
Cysticercosis of the oral cavity: report of five cases and a review of literature. Int J Paediatr Dent (1998) 1.38
Cerebral SPECT imaging: effect on clinical management. J Nucl Med (1996) 1.38
The role of routine angioscopy in vascular access surgery. J Endovasc Surg (1995) 1.38
Tubewell water quality and predictors of contamination in three flood-prone areas in Bangladesh. J Appl Microbiol (2008) 1.37
Hypoglycaemic hemiplegia due to insulinoma. J Assoc Physicians India (1993) 1.37
Genomic organization and partial duplication of the human alpha7 neuronal nicotinic acetylcholine receptor gene (CHRNA7). Genomics (1998) 1.36
Classification of hepatocellular carcinoma according to hepatocellular and biliary differentiation markers. Clinical and biological implications. Am J Pathol (1996) 1.35
Mutation and selection during the secondary response to 2-phenyloxazolone. Proc Natl Acad Sci U S A (1991) 1.35
Amino acid sequence of the alpha subunit of human leukocyte adhesion receptor Mo1 (complement receptor type 3). J Cell Biol (1988) 1.35
Partitioning of trace metals in selective chemical fractions of nearshore sediments. Environ Lett (1975) 1.35
A monoclonal antibody to human insulin receptor. Biochem Biophys Res Commun (1982) 1.33
T cell maturation: thymocyte and thymus migrant subpopulations defined with monoclonal antibodies to MHC region antigens. J Immunol (1980) 1.33
Predicting deaths among intensive care unit patients. Crit Care Med (1988) 1.32
Accelerating progress in achieving the millennium development goal for children through community-based approaches. Glob Public Health (2011) 1.32
Modulation of binding and bioactivity of insulin by anti-insulin antibody: relation to possible role of receptor self-aggregation in hormone action. Proc Natl Acad Sci U S A (1979) 1.31
Gender differences in the effects of bereavement-related psychological distress in health outcomes. Psychol Med (1999) 1.29
Burkitt-type lymphoma. Diagnosis by fine needle aspiration cytology. Acta Cytol (1987) 1.29
Part II. Analysis of data gaps pertaining to Shigella infections in low and medium human development index countries, 1984-2005. Epidemiol Infect (2007) 1.29
Differentiation of absorption and first-pass gut and hepatic metabolism in humans: studies with cyclosporine. Clin Pharmacol Ther (1995) 1.28
Role of fine needle aspiration cytology in the diagnosis of soft tissue tumours and tumour-like lesions. Cytopathology (2004) 1.28
Functional heterogeneity within Broca's area during verbal working memory. Physiol Behav (2002) 1.28
Hunger in legal immigrants in California, Texas, and Illinois. Am J Public Health (2000) 1.28
A critical appraisal of six modern classifications of ductal carcinoma in situ of the breast (DCIS): correlation with grade of associated invasive carcinoma. Histopathology (1996) 1.27