PubRank

C M Rice

Author PubWeight™ 405.24‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms. Nature 2001 42.18
2 Efficient initiation of HCV RNA replication in cell culture. Science 2000 15.12
3 Flavivirus genome organization, expression, and replication. Annu Rev Microbiol 1990 14.20
4 Nucleotide sequence of yellow fever virus: implications for flavivirus gene expression and evolution. Science 1985 8.54
5 Expression and identification of hepatitis C virus polyprotein cleavage products. J Virol 1993 8.47
6 Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA. Science 1997 7.53
7 The DNA sequence and comparative analysis of human chromosome 20. Nature 2002 7.40
8 Complete nucleotide sequence of the genomic RNA of Sindbis virus. Virology 1984 6.60
9 Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites. J Virol 1993 6.36
10 Nucleotide sequence of the 26S mRNA of Sindbis virus and deduced sequence of the encoded virus structural proteins. Proc Natl Acad Sci U S A 1981 6.08
11 Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3' nontranslated region are essential for virus replication in vivo. J Virol 2000 5.26
12 Overview of hepatitis C virus genome structure, polyprotein processing, and protein properties. Curr Top Microbiol Immunol 2000 5.17
13 Sindbis virus: an efficient, broad host range vector for gene expression in animal cells. Science 1989 4.84
14 The DNA sequence and analysis of human chromosome 6. Nature 2003 4.75
15 Identification of a highly conserved sequence element at the 3' terminus of hepatitis C virus genome RNA. J Virol 1996 4.59
16 A second hepatitis C virus-encoded proteinase. Proc Natl Acad Sci U S A 1993 4.30
17 Formation and intracellular localization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia and Sindbis viruses. J Virol 1994 4.21
18 Sindbis virus expression vectors: packaging of RNA replicons by using defective helper RNAs. J Virol 1993 4.19
19 trans-Complementation of yellow fever virus NS1 reveals a role in early RNA replication. J Virol 1997 4.17
20 Evidence that the N-terminal domain of nonstructural protein NS3 from yellow fever virus is a serine protease responsible for site-specific cleavages in the viral polyprotein. Proc Natl Acad Sci U S A 1990 4.12
21 Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide. Cell 1996 4.12
22 Processing in the hepatitis C virus E2-NS2 region: identification of p7 and two distinct E2-specific products with different C termini. J Virol 1994 3.61
23 Neutralizing antibody response during acute and chronic hepatitis C virus infection. Proc Natl Acad Sci U S A 2004 3.57
24 Sindbis virus proteins nsP1 and nsP2 contain homology to nonstructural proteins from several RNA plant viruses. J Virol 1985 3.51
25 Processing of the yellow fever virus nonstructural polyprotein: a catalytically active NS3 proteinase domain and NS2B are required for cleavages at dibasic sites. J Virol 1991 3.41
26 Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and flavivirus enzymes. J Virol 1993 3.37
27 Conserved elements in the 3' untranslated region of flavivirus RNAs and potential cyclization sequences. J Mol Biol 1987 3.30
28 The hepatitis C virus nonstructural protein 4B is an integral endoplasmic reticulum membrane protein. Virology 2001 3.25
29 Polypeptide requirements for assembly of functional Sindbis virus replication complexes: a model for the temporal regulation of minus- and plus-strand RNA synthesis. EMBO J 1994 3.00
30 An SNP map of human chromosome 22. Nature 2000 2.99
31 Association of sindbis virion glycoproteins and their precursors. J Mol Biol 1982 2.95
32 Mapping of RNA- temperature-sensitive mutants of Sindbis virus: complementation group F mutants have lesions in nsP4. J Virol 1989 2.94
33 Sequence coding for the alphavirus nonstructural proteins is interrupted by an opal termination codon. Proc Natl Acad Sci U S A 1983 2.94
34 Subcellular localization, stability, and trans-cleavage competence of the hepatitis C virus NS3-NS4A complex expressed in tetracycline-regulated cell lines. J Virol 2000 2.89
35 Yellow fever virus proteins NS2A, NS2B, and NS4B: identification and partial N-terminal amino acid sequence analysis. Virology 1989 2.87
36 Formation of native hepatitis C virus glycoprotein complexes. J Virol 1997 2.87
37 Infectious Sindbis virus transient expression vectors for studying antigen processing and presentation. Proc Natl Acad Sci U S A 1992 2.86
38 Sequence studies of several alphavirus genomic RNAs in the region containing the start of the subgenomic RNA. Proc Natl Acad Sci U S A 1982 2.77
39 HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C virus. Identification of multiple epitopes and characterization of patterns of cytokine release. J Clin Invest 1995 2.66
40 Association of the Sindbis virus RNA methyltransferase activity with the nonstructural protein nsP1. Virology 1989 2.64
41 Hepatitis C virus NS3 serine proteinase: trans-cleavage requirements and processing kinetics. J Virol 1994 2.64
42 Mutagenesis of the in-frame opal termination codon preceding nsP4 of Sindbis virus: studies of translational readthrough and its effect on virus replication. J Virol 1989 2.59
43 Cleavage at a novel site in the NS4A region by the yellow fever virus NS2B-3 proteinase is a prerequisite for processing at the downstream 4A/4B signalase site. J Virol 1993 2.56
44 Hepatitis C virus glycoprotein folding: disulfide bond formation and association with calnexin. J Virol 1996 2.53
45 Production of yellow fever virus proteins in infected cells: identification of discrete polyprotein species and analysis of cleavage kinetics using region-specific polyclonal antisera. Virology 1990 2.50
46 Selection of RNA replicons capable of persistent noncytopathic replication in mammalian cells. J Virol 1999 2.49
47 Differential cytotoxic T-lymphocyte responsiveness to the hepatitis B and C viruses in chronically infected patients. J Virol 1996 2.47
48 Determinants for membrane association of the hepatitis C virus RNA-dependent RNA polymerase. J Biol Chem 2001 2.45
49 Genetic interaction of flavivirus nonstructural proteins NS1 and NS4A as a determinant of replicase function. J Virol 1999 2.44
50 Noncytopathic Sindbis virus RNA vectors for heterologous gene expression. Proc Natl Acad Sci U S A 1998 2.44
51 Phosphorylation of the hepatitis C virus NS5A protein in vitro and in vivo: properties of the NS5A-associated kinase. J Virol 1997 2.39
52 Ross River virus 26 s RNA: complete nucleotide sequence and deduced sequence of the encoded structural proteins. Virology 1983 2.38
53 Synthesis, cleavage and sequence analysis of DNA complementary to the 26 S messenger RNA of Sindbis virus. J Mol Biol 1981 2.38
54 Patients with chronic hepatitis C have circulating cytotoxic T cells which recognize hepatitis C virus-encoded peptides binding to HLA-A2.1 molecules. J Virol 1995 2.34
55 Secondary structure determination of the conserved 98-base sequence at the 3' terminus of hepatitis C virus genome RNA. J Virol 1997 2.30
56 Roles of nonstructural polyproteins and cleavage products in regulating Sindbis virus RNA replication and transcription. J Virol 1993 2.28
57 Mutations which alter the level or structure of nsP4 can affect the efficiency of Sindbis virus replication in a host-dependent manner. J Virol 1990 2.28
58 Comparison of the virulent Asibi strain of yellow fever virus with the 17D vaccine strain derived from it. Proc Natl Acad Sci U S A 1987 2.26
59 Diverse hepatitis C virus glycoproteins mediate viral infection in a CD81-dependent manner. J Virol 2004 2.26
60 A central region in the hepatitis C virus NS4A protein allows formation of an active NS3-NS4A serine proteinase complex in vivo and in vitro. J Virol 1995 2.26
61 Mutagenesis of the yellow fever virus NS2B protein: effects on proteolytic processing, NS2B-NS3 complex formation, and viral replication. J Virol 1993 2.25
62 Neomycin resistance as a dominant selectable marker for selection and isolation of vaccinia virus recombinants. Mol Cell Biol 1985 2.19
63 West Nile virus envelope proteins: nucleotide sequence analysis of strains differing in mouse neuroinvasiveness. J Gen Virol 1998 2.18
64 Alphavirus-based expression vectors: strategies and applications. Proc Natl Acad Sci U S A 1996 2.18
65 NS2B-3 proteinase-mediated processing in the yellow fever virus structural region: in vitro and in vivo studies. J Virol 1994 2.11
66 Characterization of truncated forms of hepatitis C virus glycoproteins. J Gen Virol 1997 2.06
67 Continuous human cell lines inducibly expressing hepatitis C virus structural and nonstructural proteins. Hepatology 1998 2.05
68 Bovine viral diarrhea virus NS3 serine proteinase: polyprotein cleavage sites, cofactor requirements, and molecular model of an enzyme essential for pestivirus replication. J Virol 1997 2.00
69 Nonstructural proteins nsP3 and nsP4 of Ross River and O'Nyong-nyong viruses: sequence and comparison with those of other alphaviruses. Virology 1988 1.99
70 Molecular analysis of Sindbis virus pathogenesis in neonatal mice by using virus recombinants constructed in vitro. J Virol 1988 1.96
71 Partial nucleotide sequence of the Murray Valley encephalitis virus genome. Comparison of the encoded polypeptides with yellow fever virus structural and non-structural proteins. J Mol Biol 1986 1.96
72 Cis-acting RNA elements at the 5' end of Sindbis virus genome RNA regulate minus- and plus-strand RNA synthesis. RNA 2001 1.95
73 Yellow fever/Japanese encephalitis chimeric viruses: construction and biological properties. J Virol 1999 1.94
74 Long-term follow-up of chimpanzees inoculated with the first infectious clone for hepatitis C virus. J Virol 1999 1.93
75 Liver-derived CTL in hepatitis C virus infection: breadth and specificity of responses in a cohort of persons with chronic infection. J Immunol 1998 1.92
76 A cis-acting mutation in the Sindbis virus junction region which affects subgenomic RNA synthesis. J Virol 1989 1.92
77 Mutagenesis of the N-linked glycosylation sites of the yellow fever virus NS1 protein: effects on virus replication and mouse neurovirulence. Virology 1996 1.87
78 The efficient intracellular sequestration of the insulin-regulatable glucose transporter (GLUT-4) is conferred by the NH2 terminus. J Cell Biol 1992 1.86
79 Specificity of the hepatitis C virus NS3 serine protease: effects of substitutions at the 3/4A, 4A/4B, 4B/5A, and 5A/5B cleavage sites on polyprotein processing. J Virol 1994 1.85
80 Assembly of functional Sindbis virus RNA replication complexes: requirement for coexpression of P123 and P34. J Virol 1993 1.83
81 The NS5A/NS5 proteins of viruses from three genera of the family flaviviridae are phosphorylated by associated serine/threonine kinases. J Virol 1998 1.83
82 Infectious bovine viral diarrhea virus (strain NADL) RNA from stable cDNA clones: a cellular insert determines NS3 production and viral cytopathogenicity. J Virol 1998 1.82
83 Recombinant vaccinia virus producing the prM and E proteins of yellow fever virus protects mice from lethal yellow fever encephalitis. Virology 1992 1.76
84 Expression of Sindbis virus structural proteins via recombinant vaccinia virus: synthesis, processing, and incorporation into mature Sindbis virions. J Virol 1985 1.75
85 Genome sequences of a mouse-avirulent and a mouse-virulent strain of Ross River virus. Virology 1988 1.74
86 Isolation and characterization of noncytopathic pestivirus mutants reveals a role for nonstructural protein NS4B in viral cytopathogenicity. J Virol 2001 1.73
87 Mutagenesis of conserved residues at the yellow fever virus 3/4A and 4B/5 dibasic cleavage sites: effects on cleavage efficiency and polyprotein processing. Virology 1993 1.70
88 Genetic analysis of the yellow fever virus NS1 protein: identification of a temperature-sensitive mutation which blocks RNA accumulation. J Virol 1997 1.65
89 Identification of the major phosphorylation site of the hepatitis C virus H strain NS5A protein as serine 2321. J Biol Chem 1999 1.64
90 The physical maps for sequencing human chromosomes 1, 6, 9, 10, 13, 20 and X. Nature 2001 1.63
91 Sindbis virus mutant ts20 of complementation group E contains a lesion in glycoprotein E2. Virology 1986 1.63
92 The role of hepatitis C virus-specific cytotoxic T lymphocytes in chronic hepatitis C. J Immunol 1997 1.63
93 Mutagenesis of the yellow fever virus NS2A/2B cleavage site: effects on proteolytic processing, viral replication, and evidence for alternative processing of the NS2A protein. Virology 1994 1.63
94 Temperature sensitive shut-off of alphavirus minus strand RNA synthesis maps to a nonstructural protein, nsP4. Virology 1990 1.60
95 Phosphorylation of Sindbis virus nsP3 in vivo and in vitro. Virology 1990 1.59
96 Sequence analysis of cDNA's derived from the RNA of Sindbis virions and of defective interfering particles. J Virol 1982 1.59
97 Mutagenesis of the NS2B-NS3-mediated cleavage site in the flavivirus capsid protein demonstrates a requirement for coordinated processing. J Virol 1999 1.54
98 Pharmacologic treatment of noncognitive behavioral disturbances in elderly demented patients. Am J Psychiatry 1990 1.51
99 The signal for translational readthrough of a UGA codon in Sindbis virus RNA involves a single cytidine residue immediately downstream of the termination codon. J Virol 1993 1.50
100 Hepatitis C virus-encoded NS2-3 protease: cleavage-site mutagenesis and requirements for bimolecular cleavage. J Virol 1995 1.49
101 Biochemical studies of the maturation of the small Sindbis virus glycoprotein E3. Virology 1984 1.44
102 Template-dependent initiation of Sindbis virus RNA replication in vitro. J Virol 1998 1.43
103 Isolation and characterization of the hydrophobic COOH-terminal domains of the sindbis virion glycoproteins. J Mol Biol 1982 1.42
104 Genetic analysis of the nsP3 region of Sindbis virus: evidence for roles in minus-strand and subgenomic RNA synthesis. J Virol 1994 1.40
105 cis-acting RNA elements required for replication of bovine viral diarrhea virus-hepatitis C virus 5' nontranslated region chimeras. RNA 1998 1.40
106 ECD--a totally integrated database of Escherichia coli K12. Nucleic Acids Res 1994 1.39
107 Mutagenesis of the signal sequence of yellow fever virus prM protein: enhancement of signalase cleavage In vitro is lethal for virus production. J Virol 2000 1.35
108 Deletion and duplication mutations in the C-terminal nonconserved region of Sindbis virus nsP3: effects on phosphorylation and on virus replication in vertebrate and invertebrate cells. Virology 1994 1.35
109 Partial nucleotide sequence of St. Louis encephalitis virus RNA: structural proteins, NS1, ns2a, and ns2b. Virology 1987 1.34
110 Mutagenesis of the yellow fever virus NS2B/3 cleavage site: determinants of cleavage site specificity and effects on polyprotein processing and viral replication. J Virol 1995 1.33
111 The DNA sequence and analysis of human chromosome 13. Nature 2004 1.33
112 Partial N-terminal amino acid sequences of three nonstructural proteins of two flaviviruses. Virology 1986 1.31
113 The hepatitis C virus NS3 serine proteinase and NS4A cofactor: establishment of a cell-free trans-processing assay. Proc Natl Acad Sci U S A 1995 1.30
114 Efficient translation initiation is required for replication of bovine viral diarrhea virus subgenomic replicons. J Virol 2001 1.29
115 Functional cDNA clones of the Flaviviridae: strategies and applications. Adv Virus Res 1999 1.26
116 Sindbis virus attachment: isolation and characterization of mutants with impaired binding to vertebrate cells. J Virol 1993 1.25
117 Sindbis virus ts103 has a mutation in glycoprotein E2 that leads to defective assembly of virions. J Virol 1989 1.25
118 Neural progenitor cells from postmortem adult human retina. Br J Ophthalmol 2005 1.22
119 Mechanism of action of a pestivirus antiviral compound. Proc Natl Acad Sci U S A 2000 1.21
120 CD8+ T cell recognition of an endogenously processed epitope is regulated primarily by residues within the epitope. J Exp Med 1992 1.17
121 Infectious enveloped RNA virus antigenic chimeras. Proc Natl Acad Sci U S A 1992 1.16
122 Replication of yellow fever virus in the mouse central nervous system: comparison of neuroadapted and non-neuroadapted virus and partial sequence analysis of the neuroadapted strain. J Gen Virol 1996 1.15
123 The DNA sequence and comparative analysis of human chromosome 10. Nature 2004 1.14
124 A single nucleotide change in the 5' noncoding region of Sindbis virus confers neurovirulence in rats. J Virol 1999 1.11
125 The expression of chloramphenicol acetyltransferase in Aedes albopictus (C6/36) cells and Aedes triseriatus mosquitoes using a double subgenomic recombinant Sindbis virus. Insect Biochem Mol Biol 1994 1.07
126 Molecular virology of hepatitis C virus: an update with respect to potential antiviral targets. Antivir Ther 1998 1.05
127 Genetic determinants of Sindbis virus neuroinvasiveness. J Virol 1997 1.01
128 Rescue of Sindbis virus-specific RNA replication and transcription by using a vaccinia virus recombinant. J Virol 1991 1.01
129 Molecular characterization of hepatitis C virus. Curr Stud Hematol Blood Transfus 1998 1.00
130 RNA viruses as gene expression vectors. Virus Genes 1989 0.99
131 Enhancement of Sindbis virus self-replicating RNA vaccine potency by linkage of Mycobacterium tuberculosis heat shock protein 70 gene to an antigen gene. J Immunol 2001 0.97
132 Complete nucleotide sequence of yellow fever virus vaccine strains 17DD and 17D-213. Virus Res 1995 0.97
133 Seronegative limbic encephalitis: case report, literature review and proposed treatment algorithm. Pract Neurol 2011 0.97
134 Multiple tachykinins are produced and secreted upon post-translational processing of the three substance P precursor proteins, alpha-, beta-, and gamma-preprotachykinin. Expression of the preprotachykinins in AtT-20 cells infected with vaccinia virus recombinants. J Biol Chem 1989 0.95
135 Heterogeneity in envelope protein sequence and N-linked glycosylation among yellow fever virus vaccine strains. Virology 1992 0.95
136 In vitro human Th-cell responses to a recombinant hepatitis C virus antigen: failure in IL-2 production despite proliferation. Hum Immunol 1999 0.94
137 Rubella virus-specific cytotoxic T-lymphocyte responses: identification of the capsid as a target of major histocompatibility complex class I-restricted lysis and definition of two epitopes. J Virol 1993 0.93
138 From long range mapping to sequence-ready contigs on human chromosome 6. DNA Seq 1997 0.93
139 Transcriptional activation of the interleukin-2 promoter by hepatitis C virus core protein. J Virol 2001 0.92
140 Bad time for Bonzo? Experimental models of hepatitis C virus infection, replication, and pathogenesis. Hepatology 2001 0.91
141 Sequence of the 3' half of the Murray Valley encephalitis virus genome and mapping of the nonstructural proteins NS1, NS3, and NS5. Virus Genes 1990 0.91
142 Hepatitis C virus cell culture replication systems: their potential use for the development of antiviral therapies. Curr Opin Infect Dis 2001 0.88
143 Genetic variation in CLDN1 and susceptibility to hepatitis C virus infection. J Viral Hepat 2009 0.88
144 Immunization with nonstructural proteins promotes functional recovery of alphavirus-infected neurons. J Virol 1997 0.83
145 Expression of the structural proteins of dengue 2 virus and yellow fever virus by recombinant vaccinia viruses. Arch Virol 1990 0.82
146 The role of host immunocompetence in neuroinvasion of Sindbis virus. Arch Virol 1999 0.81
147 Functionally distinct T-cell epitopes within the hepatitis C virus non-structural 3 protein. Hum Immunol 1999 0.81
148 Induction of hepatitis C virus-specific cytotoxic T lymphocytes in mice by immunization with dendritic cells treated with an anthrax toxin fusion protein. Vaccine 2001 0.80
149 Class I MHC molecule-mediated inhibition of Sindbis virus replication. J Immunol 1999 0.79
150 Cloning and assembly of complex libraries of full-length HCV cDNA clones. Methods Mol Med 1999 0.79
151 Use of enzyme immunoassay and nucleic acid hybridization for detecting Sindbis virus in infected mosquitoes. J Virol Methods 1987 0.77
152 Use of the vaccinia virus/t7 expression system for studying HCV protein processing. Methods Mol Med 1999 0.77
153 Expression and Characterization of the HCV NS2 Protease. Methods Mol Med 1999 0.77
154 The N-terminus of PE2 in Sindbis virus-infected cells. Virology 1982 0.76
155 Molecular biology of the flaviviruses. Microbiol Sci 1987 0.76
156 The Chromosome 6 database at the Sanger Centre. DNA Seq 1997 0.75
157 Brain biopsy in benign neurological disease. J Neurol 2012 0.75
158 Detection of yellow fever virus nucleic acid in infected mosquitoes by RNA:RNA in situ hybridization. Mol Cell Probes 1988 0.75
159 Construction of recombinant sindbis-based expression vectors for the study of HCV genes and their products. Methods Mol Med 1999 0.75