Formation and intracellular localization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia and Sindbis viruses.

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Published in J Virol on October 01, 1994

Authors

J Dubuisson1, H H Hsu, R C Cheung, H B Greenberg, D G Russell, C M Rice

Author Affiliations

1: Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri 63110-1093.

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Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites. J Virol (1993) 6.36

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The isolation of simian virus 40 variants with specifically altered genomes. Proc Natl Acad Sci U S A (1974) 4.35

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Sindbis virus expression vectors: packaging of RNA replicons by using defective helper RNAs. J Virol (1993) 4.19

Non-A, non-B hepatitis in chimpanzees and marmosets. J Infect Dis (1981) 4.15

Vaccination of chimpanzees against infection by the hepatitis C virus. Proc Natl Acad Sci U S A (1994) 3.76

Proteolytic processing and membrane association of putative nonstructural proteins of hepatitis C virus. Proc Natl Acad Sci U S A (1993) 3.68

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Expression, identification and subcellular localization of the proteins encoded by the hepatitis C viral genome. J Gen Virol (1993) 3.18

Vaccinia virus replication. I. Requirement for the host-cell nucleus. J Virol (1979) 3.10

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A new method for simultaneous purification of cytochrome b5 and NADPH-cytochrome c reductase from rat liver microsomes. J Biochem (1970) 2.54

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Primary structure of the Streptomyces enzyme endo-beta-N-acetylglucosaminidase H. J Biol Chem (1984) 2.40

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Cross-linking of the components of lactose synthetase with dimethylpimelimidate. J Biol Chem (1975) 1.98

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Infectious Sindbis virus transient expression vectors for studying antigen processing and presentation. Proc Natl Acad Sci U S A (1992) 2.86

Three-dimensional structure of rhesus rotavirus by cryoelectron microscopy and image reconstruction. J Cell Biol (1990) 2.83

Effect of human leukocyte interferon on hepatitis B virus infection in patients with chronic active hepatitis. N Engl J Med (1976) 2.80

Detection of Norwalk virus in stool specimens by reverse transcriptase-polymerase chain reaction and nonradioactive oligoprobes. J Clin Microbiol (1992) 2.77

Sequence studies of several alphavirus genomic RNAs in the region containing the start of the subgenomic RNA. Proc Natl Acad Sci U S A (1982) 2.77

Infectious rotavirus enters cells by direct cell membrane penetration, not by endocytosis. J Virol (1988) 2.72

Microtiter solid-phase radioimmunoassay for detection of Escherichia coli heat-labile enterotoxin. Infect Immun (1977) 2.72

HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C virus. Identification of multiple epitopes and characterization of patterns of cytokine release. J Clin Invest (1995) 2.66

Trafficking and release of mycobacterial lipids from infected macrophages. Traffic (2000) 2.65

Association of the Sindbis virus RNA methyltransferase activity with the nonstructural protein nsP1. Virology (1989) 2.64

Hepatitis C virus NS3 serine proteinase: trans-cleavage requirements and processing kinetics. J Virol (1994) 2.64

Multiple-challenge study of host susceptibility to Norwalk gastroenteritis in US adults. J Infect Dis (1990) 2.63

Mutagenesis of the in-frame opal termination codon preceding nsP4 of Sindbis virus: studies of translational readthrough and its effect on virus replication. J Virol (1989) 2.59

The green prescription study: a randomized controlled trial of written exercise advice provided by general practitioners. Am J Public Health (1998) 2.59

Proteins of Norwalk virus. J Virol (1981) 2.59

Viral gastroenteritis. N Engl J Med (1991) 2.58

Cleavage at a novel site in the NS4A region by the yellow fever virus NS2B-3 proteinase is a prerequisite for processing at the downstream 4A/4B signalase site. J Virol (1993) 2.56

Hepatitis C virus glycoprotein folding: disulfide bond formation and association with calnexin. J Virol (1996) 2.53

Mycobacterium-containing phagosomes are accessible to early endosomes and reflect a transitional state in normal phagosome biogenesis. EMBO J (1996) 2.52

Complement receptor-mediated uptake and tumor necrosis factor-alpha-mediated growth inhibition of Mycobacterium tuberculosis by human alveolar macrophages. J Immunol (1994) 2.52

Production of yellow fever virus proteins in infected cells: identification of discrete polyprotein species and analysis of cleavage kinetics using region-specific polyclonal antisera. Virology (1990) 2.50

Selection of RNA replicons capable of persistent noncytopathic replication in mammalian cells. J Virol (1999) 2.49

Differential cytotoxic T-lymphocyte responsiveness to the hepatitis B and C viruses in chronically infected patients. J Virol (1996) 2.47

Determinants for membrane association of the hepatitis C virus RNA-dependent RNA polymerase. J Biol Chem (2001) 2.45

Noncytopathic Sindbis virus RNA vectors for heterologous gene expression. Proc Natl Acad Sci U S A (1998) 2.44

Genetic interaction of flavivirus nonstructural proteins NS1 and NS4A as a determinant of replicase function. J Virol (1999) 2.44

CCR7 expression and memory T cell diversity in humans. J Immunol (2001) 2.42

The isolation and characterization of a Norwalk virus-specific cDNA. J Clin Invest (1991) 2.42