Published in J Neurochem on January 01, 2001
Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum. Proc Natl Acad Sci U S A (2004) 3.87
Neuroplasticity in the mesolimbic dopamine system and cocaine addiction. Br J Pharmacol (2008) 2.83
From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning. Learn Mem (2002) 2.79
Epigenetic mechanisms in cognition. Neuron (2011) 2.31
ERK/MAPK regulates hippocampal histone phosphorylation following contextual fear conditioning. Learn Mem (2006) 2.08
RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice. EMBO J (2004) 2.08
Regionally specific regulation of ERK MAP kinase in a model of antidepressant-sensitive chronic depression. Biol Psychiatry (2007) 2.01
Deletion of ERK2 mitogen-activated protein kinase identifies its key roles in cortical neurogenesis and cognitive function. J Neurosci (2008) 1.84
Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior. Neuron (2008) 1.80
Histone acetylation: molecular mnemonics on the chromatin. Nat Rev Neurosci (2013) 1.77
Sources and targets of reactive oxygen species in synaptic plasticity and memory. Antioxid Redox Signal (2007) 1.69
Mechanisms of chronic central neuropathic pain after spinal cord injury. Brain Res Rev (2008) 1.69
Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: advantages and limitations. Biochem Pharmacol (2011) 1.68
Genomic analysis of sleep deprivation reveals translational regulation in the hippocampus. Physiol Genomics (2012) 1.64
Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndrome. Nat Neurosci (2014) 1.63
Synaptic plasticity and phosphorylation. Pharmacol Ther (2006) 1.58
MAPK, CREB and zif268 are all required for the consolidation of recognition memory. Philos Trans R Soc Lond B Biol Sci (2003) 1.56
"Silent" metaplasticity of the late phase of long-term potentiation requires protein phosphatases. Learn Mem (2002) 1.52
Networks of neurons, networks of genes: an integrated view of memory consolidation. Neurobiol Learn Mem (2007) 1.51
Role of ventral tegmental area glial cell line-derived neurotrophic factor in incubation of cocaine craving. Biol Psychiatry (2009) 1.48
Hippocampal alpha4beta2 nicotinic acetylcholine receptor involvement in the enhancing effect of acute nicotine on contextual fear conditioning. J Neurosci (2007) 1.48
New technologies for examining the role of neuronal ensembles in drug addiction and fear. Nat Rev Neurosci (2013) 1.45
Microelectrode array recordings of cultured hippocampal networks reveal a simple model for transcription and protein synthesis-dependent plasticity. J Physiol (2004) 1.41
Central amygdala extracellular signal-regulated kinase signaling pathway is critical to incubation of opiate craving. J Neurosci (2008) 1.39
The role of protein synthesis in memory consolidation: progress amid decades of debate. Neurobiol Learn Mem (2007) 1.39
Reactive oxygen species in the regulation of synaptic plasticity and memory. Antioxid Redox Signal (2010) 1.37
Cyclic changes in estradiol regulate synaptic plasticity through the MAP kinase pathway. Proc Natl Acad Sci U S A (2001) 1.36
GDNF is a fast-acting potent inhibitor of alcohol consumption and relapse. Proc Natl Acad Sci U S A (2008) 1.35
Synaptic plasticity deficits and mild memory impairments in mouse models of chronic granulomatous disease. Mol Cell Biol (2006) 1.35
The influences of diet and exercise on mental health through hormesis. Ageing Res Rev (2007) 1.34
Insulin in central nervous system: more than just a peripheral hormone. J Aging Res (2012) 1.33
Modelling the molecular mechanisms of synaptic plasticity using systems biology approaches. Nat Rev Neurosci (2010) 1.32
Altered phosphorylation and localization of the A-type channel, Kv4.2 in status epilepticus. J Neurochem (2008) 1.32
Synergistic interaction between adenosine A2A and glutamate mGlu5 receptors: implications for striatal neuronal function. Proc Natl Acad Sci U S A (2002) 1.30
Nicotinic acetylcholine receptor-mediated calcium signaling in the nervous system. Acta Pharmacol Sin (2009) 1.30
Hippocampal Mek/Erk signaling mediates extinction of contextual freezing behavior. Neurobiol Learn Mem (2006) 1.29
MAPK pathway activation in pilocytic astrocytoma. Cell Mol Life Sci (2011) 1.28
Calcium signaling in neurodegeneration. Mol Neurodegener (2009) 1.27
Interleukin-1 beta impairs brain derived neurotrophic factor-induced signal transduction. Neurobiol Aging (2007) 1.26
Hormonal regulation of hippocampal dendritic morphology and synaptic plasticity. Cell Adh Migr (2008) 1.24
Neurotransmitters drive combinatorial multistate postsynaptic density networks. Sci Signal (2009) 1.24
Hippocampal function in cognition. Psychopharmacology (Berl) (2004) 1.24
Maladaptive striatal plasticity in L-DOPA-induced dyskinesia. Prog Brain Res (2010) 1.23
Amyloid-β as a modulator of synaptic plasticity. J Alzheimers Dis (2010) 1.22
Activation of Erk and JNK MAPK pathways by acute swim stress in rat brain regions. BMC Neurosci (2004) 1.22
NADPH oxidase is required for NMDA receptor-dependent activation of ERK in hippocampal area CA1. J Neurochem (2005) 1.21
Biological mechanisms of physical activity in preventing cognitive decline. Cell Mol Neurobiol (2009) 1.20
Lactate promotes plasticity gene expression by potentiating NMDA signaling in neurons. Proc Natl Acad Sci U S A (2014) 1.18
Activation of extracellular signal-regulated kinase in the anterior cingulate cortex contributes to the induction and expression of affective pain. J Neurosci (2009) 1.13
L-type Ca2+ channels mediate adaptation of extracellular signal-regulated kinase 1/2 phosphorylation in the ventral tegmental area after chronic amphetamine treatment. J Neurosci (2004) 1.12
Nicotinic receptor agonists as neuroprotective/neurotrophic drugs. Progress in molecular mechanisms. J Neural Transm (Vienna) (2006) 1.11
Signaling mechanisms mediating BDNF modulation of memory formation in vivo in the hippocampus. Cell Mol Neurobiol (2002) 1.11
Formation of chimeric genes by copy-number variation as a mutational mechanism in schizophrenia. Am J Hum Genet (2013) 1.10
Estradiol-dependent modulation of auditory processing and selectivity in songbirds. Front Neuroendocrinol (2010) 1.09
Insulin receptor signaling in long-term memory consolidation following spatial learning. Learn Mem (2005) 1.08
Estradiol-induced enhancement of object memory consolidation involves NMDA receptors and protein kinase A in the dorsal hippocampus of female C57BL/6 mice. Behav Neurosci (2008) 1.07
GDNF--a potential target to treat addiction. Pharmacol Ther (2008) 1.07
Acute or chronic stress induce cell compartment-specific phosphorylation of glucocorticoid receptor and alter its transcriptional activity in Wistar rat brain. J Endocrinol (2009) 1.06
Altered proliferation and networks in neural cells derived from idiopathic autistic individuals. Mol Psychiatry (2016) 1.05
Physiology and pathology of calcium signaling in the brain. Front Pharmacol (2012) 1.05
Inhibition of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) signaling in the striatum reverts motor symptoms associated with L-dopa-induced dyskinesia. Proc Natl Acad Sci U S A (2010) 1.05
Abnormal activity of the MAPK- and cAMP-associated signaling pathways in frontal cortical areas in postmortem brain in schizophrenia. Neuropsychopharmacology (2011) 1.05
Importance of ERK activation in behavioral and biochemical effects induced by MDMA in mice. Br J Pharmacol (2003) 1.05
Opposing synaptic regulation of amyloid-β metabolism by NMDA receptors in vivo. J Neurosci (2011) 1.04
Loss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease. J Neurosci (2010) 1.04
Evidence for the presence of a novel Kv4-mediated A-type K(+) channel-modifying factor. J Physiol (2001) 1.03
Molecular mechanisms underlying memory consolidation of taste information in the cortex. Front Behav Neurosci (2012) 1.02
Phrenic long-term facilitation after acute intermittent hypoxia requires spinal ERK activation but not TrkB synthesis. J Appl Physiol (1985) (2012) 1.02
Serotonergic mechanisms in addiction-related memories. Behav Brain Res (2008) 1.01
Brevetoxin activation of voltage-gated sodium channels regulates Ca dynamics and ERK1/2 phosphorylation in murine neocortical neurons. J Neurochem (2004) 0.99
The impact of flavonoids on spatial memory in rodents: from behaviour to underlying hippocampal mechanisms. Genes Nutr (2009) 0.99
Visual stimulation activates ERK in synaptic and somatic compartments of rat cortical neurons with parallel kinetics. PLoS One (2007) 0.99
Iron mediates N-methyl-D-aspartate receptor-dependent stimulation of calcium-induced pathways and hippocampal synaptic plasticity. J Biol Chem (2011) 0.97
Outcome of array CGH analysis for 255 subjects with intellectual disability and search for candidate genes using bioinformatics. Hum Genet (2010) 0.97
Plasticity within striatal direct pathway neurons after neonatal dopamine depletion is mediated through a novel functional coupling of serotonin 5-HT2 receptors to the ERK 1/2 map kinase pathway. J Comp Neurol (2006) 0.97
Sexual experience in female rodents: cellular mechanisms and functional consequences. Brain Res (2006) 0.96
Involvement of oxidative pathways in cytokine-induced secretory phospholipase A2-IIA in astrocytes. Neurochem Int (2009) 0.96
Extracellular signal-regulated kinase in the basolateral amygdala, but not the nucleus accumbens core, is critical for context-response-cocaine memory reconsolidation in rats. Neuropsychopharmacology (2012) 0.96
Subcellular location of PKA controls striatal plasticity: stochastic simulations in spiny dendrites. PLoS Comput Biol (2012) 0.94
Antipsychotic drugs elevate mRNA levels of presynaptic proteins in the frontal cortex of the rat. Biol Psychiatry (2005) 0.94
The growth compromised HSV-2 mutant DeltaRR prevents kainic acid-induced apoptosis and loss of function in organotypic hippocampal cultures. Brain Res (2006) 0.94
Sex differences in anxiety and depression: role of testosterone. Front Neuroendocrinol (2013) 0.94
BDNF-mediated regulation of ethanol consumption requires the activation of the MAP kinase pathway and protein synthesis. Eur J Neurosci (2012) 0.93
Extracellular signal-regulated kinase 1/2 involvement in the enhancement of contextual fear conditioning by nicotine. Behav Neurosci (2007) 0.93
Dopamine promotes striatal neuronal apoptotic death via ERK signaling cascades. Eur J Neurosci (2009) 0.92
17-Beta-estradiol-mediated activation of extracellular-signal regulated kinase, phosphatidylinositol 3-kinase/protein kinase B-Akt and N-methyl-D-aspartate receptor phosphorylation in cortical synaptoneurosomes. J Neurochem (2007) 0.92
Brain deletion of insulin receptor substrate 2 disrupts hippocampal synaptic plasticity and metaplasticity. PLoS One (2012) 0.92
Bioluminescence methodology for the detection of protein-protein interactions within the voltage-gated sodium channel macromolecular complex. Assay Drug Dev Technol (2012) 0.92
Neuritin activates insulin receptor pathway to up-regulate Kv4.2-mediated transient outward K+ current in rat cerebellar granule neurons. J Biol Chem (2012) 0.92
Nicotine withdrawal disrupts both foreground and background contextual fear conditioning but not pre-pulse inhibition of the acoustic startle response in C57BL/6 mice. Behav Brain Res (2008) 0.92
Pleurotus giganteus (Berk.) Karunarathna & K.D. Hyde: Nutritional value and in vitro neurite outgrowth activity in rat pheochromocytoma cells. BMC Complement Altern Med (2012) 0.92
Nicotine ameliorates NMDA receptor antagonist-induced deficits in contextual fear conditioning through high-affinity nicotinic acetylcholine receptors in the hippocampus. Neuropharmacology (2010) 0.91
Synaptic and genomic responses to JNK and AP-1 signaling in Drosophila neurons. BMC Neurosci (2005) 0.91
Psychostimulants, L-type calcium channels, kinases, and phosphatases. Neuroscientist (2005) 0.91
PhosphoregDB: the tissue and sub-cellular distribution of mammalian protein kinases and phosphatases. BMC Bioinformatics (2006) 0.91
Mechanisms of neuroprotection from hypoxia-ischemia (HI) brain injury by up-regulation of cytoglobin (CYGB) in a neonatal rat model. J Biol Chem (2013) 0.91
Regulation of cpg15 by signaling pathways that mediate synaptic plasticity. Mol Cell Neurosci (2003) 0.91
IL-6 regulation of synaptic function in the CNS. Neuropharmacology (2014) 0.91
Polygalasaponin XXXII from Polygala tenuifolia root improves hippocampal-dependent learning and memory. Acta Pharmacol Sin (2009) 0.90
Structural and functional modifications in glutamateric synapses following prolonged ethanol exposure. Alcohol Clin Exp Res (2006) 0.90