Published in Circulation on February 20, 2001
Use of ramipril in preventing stroke: double blind randomised trial. BMJ (2002) 4.91
Effect of lower targets for blood pressure and LDL cholesterol on atherosclerosis in diabetes: the SANDS randomized trial. JAMA (2008) 3.16
Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy. Proc Natl Acad Sci U S A (2002) 2.96
Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice. Cardiovasc Diabetol (2005) 2.88
The relationship between dose of vitamin E and suppression of oxidative stress in humans. Free Radic Biol Med (2007) 2.62
Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities. Antioxid Redox Signal (2010) 2.11
Peripheral artery disease: current insight into the disease and its diagnosis and management. Mayo Clin Proc (2010) 1.58
Mineralocorticoid receptors in vascular function and disease. Mol Cell Endocrinol (2011) 1.38
Arterial remodeling associates with CKD progression. J Am Soc Nephrol (2011) 1.32
Carotid vascular abnormalities in primary hyperparathyroidism. J Clin Endocrinol Metab (2009) 1.26
Placental growth factor mediates aldosterone-dependent vascular injury in mice. J Clin Invest (2010) 1.17
Effect of high-dose alpha-tocopherol supplementation on biomarkers of oxidative stress and inflammation and carotid atherosclerosis in patients with coronary artery disease. Am J Clin Nutr (2007) 1.14
Hyperglycemia and endothelial dysfunction in atherosclerosis: lessons from type 1 diabetes. Int J Vasc Med (2012) 1.12
Modulating an oxidative-inflammatory cascade: potential new treatment strategy for improving glucose metabolism, insulin resistance, and vascular function. Int J Clin Pract (2008) 1.10
The renin-angiotensin system modulates inflammatory processes in atherosclerosis: evidence from basic research and clinical studies. Mediators Inflamm (2009) 1.05
F2-isoprostanes as an indicator and risk factor for coronary heart disease. Free Radic Biol Med (2010) 1.04
Mechanisms of oxidative stress and vascular dysfunction. Postgrad Med J (2003) 0.98
A single-center, open, comparative study of the effect of using self-monitoring of blood glucose to guide therapy on preclinical atherosclerotic markers in type 2 diabetic subjects. J Diabetes Sci Technol (2010) 0.98
Carotid bruit for detection of hemodynamically significant carotid stenosis: the Northern Manhattan Study. Neurol Res (2009) 0.95
Comparison of inhibitors of superoxide generation in vascular smooth muscle cells. Br J Pharmacol (2009) 0.93
Risk factor management to prevent first stroke. Neurol Clin (2008) 0.92
Peripheral arterial occlusive disease: magnetic resonance imaging and the role of aggressive medical management. World J Surg (2007) 0.90
Angiotensin AT(1) receptor signalling modulates reparative angiogenesis induced by limb ischaemia. Br J Pharmacol (2002) 0.90
Angiotensin-converting enzyme inhibition down-regulates the pro-atherogenic chemokine receptor 9 (CCR9)-chemokine ligand 25 (CCL25) axis. J Biol Chem (2010) 0.86
Milk casein-derived tripeptides, VPP and IPP induced NO production in cultured endothelial cells and endothelium-dependent relaxation of isolated aortic rings. Heart Vessels (2011) 0.86
Oxidative stress in cardiovascular inflammation: its involvement in autoimmune responses. Int J Inflam (2011) 0.85
Effect of insulin glargine and n-3FA on carotid intima-media thickness in people with dysglycemia at high risk for cardiovascular events: the glucose reduction and atherosclerosis continuing evaluation study (ORIGIN-GRACE). Diabetes Care (2013) 0.85
Effects of candesartan cilexetil on carotid remodeling in hypertensive diabetic patients: the MITEC study. Vasc Health Risk Manag (2009) 0.85
Albumin thiol oxidation and serum protein carbonyl formation are progressively enhanced with advancing stages of chronic kidney disease. Clin Exp Nephrol (2009) 0.85
Cilostazol reduces the progression of carotid intima-media thickness without increasing the risk of bleeding in patients with acute coronary syndrome during a 2-year follow-up. Heart Vessels (2010) 0.84
Gender differences in utilization of effective cardiovascular secondary prevention: a Cleveland clinic prevention database study. J Womens Health (Larchmt) (2008) 0.84
Emerging roles of mitochondria ROS in atherosclerotic lesions: causation or association? J Atheroscler Thromb (2014) 0.84
Optimal therapeutic strategy for treating patients with hypertension and atherosclerosis: focus on olmesartan medoxomil. Vasc Health Risk Manag (2011) 0.84
Impact of ezetimibe on atherosclerosis: is the jury still out? Mayo Clin Proc (2009) 0.83
Effect of rosiglitazone/ramipril on preclinical vasculopathy in newly diagnosed, untreated diabetes and IGT patients: 1-year randomised, double-blind, placebo-controlled study. Eur J Clin Pharmacol (2007) 0.83
Augmentation of the renin-angiotensin system by hypercholesterolemia promotes vascular diseases. Future Lipidol (2008) 0.83
Peripheral artery disease: potential role of ACE-inhibitor therapy. Vasc Health Risk Manag (2008) 0.83
[Cardiovascular secondary prevention]. Clin Res Cardiol (2006) 0.82
ACE inhibition in secondary prevention: are the results controversial? Clin Res Cardiol (2006) 0.82
Effects of combination tocopherols and alpha lipoic acid therapy on oxidative stress and inflammatory biomarkers in chronic kidney disease. J Ren Nutr (2010) 0.82
Effect of rosiglitazone on progression of atherosclerosis: insights using 3D carotid cardiovascular magnetic resonance. J Cardiovasc Magn Reson (2009) 0.82
Management of carotid artery stenosis. Update for family physicians. Can Fam Physician (2005) 0.81
Oxidative inhibition of the vascular Na+-K+ pump via NADPH oxidase-dependent β1-subunit glutathionylation: implications for angiotensin II-induced vascular dysfunction. Free Radic Biol Med (2013) 0.81
Effects of cilostazol against the progression of carotid IMT in symptomatic ischemic stroke patients. J Neurol (2012) 0.81
Imaging outcomes in cardiovascular clinical trials. Nat Rev Cardiol (2009) 0.80
Local Augmented Angiotensinogen Secreted from Apoptotic Vascular Endothelial Cells Is a Vital Mediator of Vascular Remodelling. PLoS One (2015) 0.79
No HOPE without proof: do ARBs meet the standard for cardiovascular protection? Medscape J Med (2008) 0.79
The role of glucosamine-induced ER stress in diabetic atherogenesis. Exp Diabetes Res (2012) 0.79
Influence of the angiotensin converting enzyme inhibitor ramipril on high-sensitivity C-reactive protein (hs-CRP) in patients with documented atherosclerosis. Z Kardiol (2005) 0.79
Establishment and ultrasound characteristics of atherosclerosis in rhesus monkey. Biomed Eng Online (2015) 0.79
Reconvene and reconnect the antioxidant hypothesis in human health and disease. Indian J Clin Biochem (2010) 0.78
Effects of antihypertensive drugs on carotid intima-media thickness: Focus on angiotensin II receptor blockers. A review of randomized, controlled trials. Integr Blood Press Control (2009) 0.78
Differential impacts of blood pressure and lipid lowering on regression of ventricular and arterial mass: the Stop Atherosclerosis in Native Diabetics Trial. Hypertension (2011) 0.77
Differing Relations to Early Atherosclerosis between Vitamin C from Supplements vs. Food in the Los Angeles Atherosclerosis Study: A Prospective Cohort Study. Open Cardiovasc Med J (2012) 0.77
Treatment of diabetic vasculopathy with rosiglitazone and ramipril: Hype or hope? Int J Diabetes Dev Ctries (2009) 0.77
Effects of ramipril on serum monocyte chemoattractant protein 1, interleukin-18, and interleukin-10 in elderly patients with acute coronary syndrome. Heart Vessels (2010) 0.77
Antioxidant effects of curcuminoids in patients with type 2 diabetes mellitus: a randomized controlled trial. Inflammopharmacology (2016) 0.77
Antioxidants and cardiovascular disease: Still a topic of interest. Environ Health Prev Med (2004) 0.76
Low-glycaemic index diet to improve glycaemic control and cardiovascular disease in type 2 diabetes: design and methods for a randomised, controlled, clinical trial. BMJ Open (2016) 0.76
Vitamin E does not slow the progression of hypercholesterolemic atherosclerosis. Int J Angiol (2009) 0.76
Carotid Intima-media Thickness Measurements: Relations with Atherosclerosis, Risk of Cardiovascular Disease and Application in Randomized Controlled Trials. Chin Med J (Engl) (2016) 0.76
Cardiac and vascular protection: the potential of ONTARGET. Medscape J Med (2008) 0.75
Impact of medical therapy on atheroma volume measured by different cardiovascular imaging modalities. Cardiol Res Pract (2010) 0.75
Effect of angiotensin-converting enzyme inhibition on C-reactive protein levels: the ramipril C-reactive pRotein randomized evaluation (4R) trial results. Can J Cardiol (2009) 0.75
Effect of rosiglitazone and ramipril on macrovasculopathy in patients with type 2 diabetes: needs longer treatment and/or higher doses? Clin Pharmacol (2010) 0.75
Dose response of ACE inhibitors: implications of the SECURE trial. Curr Control Trials Cardiovasc Med (2001) 0.75
Association of depression with common carotid artery intima media thickness and augmentation index in a large Urban South Indian population- The Chennai Urban Rural Epidemiology Study (CURES - 138). Indian J Endocrinol Metab (2015) 0.75
Carotid artery intima-media thickness and the renin-angiotensin system. Hosp Pract (1995) (2013) 0.75
Comparison of brachial and carotid artery ultrasound for assessing extent of subclinical atherosclerosis in HIV: a prospective cohort study. AIDS Res Ther (2009) 0.75
A novel approach to treatment of hypertension in diabetic patients - a multicenter, double-blind, randomized study comparing the efficacy of combination therapy of Eprosartan versus Ramipril with low-dose Hydrochlorothiazide and Moxonidine on blood pressure levels in patients with hypertension and associated diabetes mellitus type 2 - rationale and design [ISRCTN55725285]. Curr Control Trials Cardiovasc Med (2004) 0.75
[Nutrition]. Z Kardiol (2005) 0.75
Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med (2000) 29.25
A global optimisation method for robust affine registration of brain images. Med Image Anal (2001) 27.87
Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm. IEEE Trans Med Imaging (2001) 25.22
Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med (2001) 20.20
Beta blockade during and after myocardial infarction: an overview of the randomized trials. Prog Cardiovasc Dis (1985) 19.03
Entropic elasticity of lambda-phage DNA. Science (1994) 15.40
Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial. Lancet (2006) 15.32
A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science (1995) 15.20
Intravenous and intracoronary fibrinolytic therapy in acute myocardial infarction: overview of results on mortality, reinfarction and side-effects from 33 randomized controlled trials. Eur Heart J (1985) 9.28
Community study of role of viral infections in exacerbations of asthma in 9-11 year old children. BMJ (1995) 9.26
The relationship between glucose and incident cardiovascular events. A metaregression analysis of published data from 20 studies of 95,783 individuals followed for 12.4 years. Diabetes Care (1999) 9.16
Large-scale temporal gene expression mapping of central nervous system development. Proc Natl Acad Sci U S A (1998) 9.06
Albuminuria and risk of cardiovascular events, death, and heart failure in diabetic and nondiabetic individuals. JAMA (2001) 8.80
Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study. Lancet (2001) 8.54
Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. The SOLVD Investigattors. N Engl J Med (1992) 8.38
Differences in risk factors, atherosclerosis, and cardiovascular disease between ethnic groups in Canada: the Study of Health Assessment and Risk in Ethnic groups (SHARE) Lancet (2000) 8.01
Why do we need some large, simple randomized trials? Stat Med (1985) 7.67
An overview of randomized trials of rehabilitation with exercise after myocardial infarction. Circulation (1989) 6.87
Effects of a polypill (Polycap) on risk factors in middle-aged individuals without cardiovascular disease (TIPS): a phase II, double-blind, randomised trial. Lancet (2009) 6.83
Emerging epidemic of cardiovascular disease in developing countries. Circulation (1998) 6.41
Renal insufficiency as a predictor of cardiovascular outcomes and the impact of ramipril: the HOPE randomized trial. Ann Intern Med (2001) 6.38
Relation between portal pressure response to pharmacotherapy and risk of recurrent variceal haemorrhage in patients with cirrhosis. Lancet (1995) 6.06
Reduction in fatal pulmonary embolism and venous thrombosis by perioperative administration of subcutaneous heparin. Overview of results of randomized trials in general, orthopedic, and urologic surgery. N Engl J Med (1988) 5.81
Assessment of cardiovascular risk by use of multiple-risk-factor assessment equations: a statement for healthcare professionals from the American Heart Association and the American College of Cardiology. Circulation (1999) 5.62
Vitamin E supplementation and cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med (2000) 5.09
The DNA sequence and analysis of human chromosome 6. Nature (2003) 4.75
The relationship between dysglycaemia and cardiovascular and renal risk in diabetic and non-diabetic participants in the HOPE study: a prospective epidemiological analysis. Diabetologia (2005) 4.45
Risk factors for acute myocardial infarction in Indians: a case-control study. Lancet (1996) 4.28
Prediction of mortality and morbidity with a 6-minute walk test in patients with left ventricular dysfunction. SOLVD Investigators. JAMA (1993) 4.01
Reduction of cardiovascular risk by regression of electrocardiographic markers of left ventricular hypertrophy by the angiotensin-converting enzyme inhibitor ramipril. Circulation (2001) 3.96
Systematic implementation of an advance directive program in nursing homes: a randomized controlled trial. JAMA (2000) 3.87
A cytogenetic survey of 14,069 newborn infants. I. Incidence of chromosome abnormalities. Clin Genet (1975) 3.81
Overcoming the limitations of current meta-analysis of randomised controlled trials. Lancet (1998) 3.79
Blood-pressure reduction and cardiovascular risk in HOPE study. Lancet (2002) 3.77
Comparison of neuroendocrine activation in patients with left ventricular dysfunction with and without congestive heart failure. A substudy of the Studies of Left Ventricular Dysfunction (SOLVD). Circulation (1990) 3.72
Coronary heart disease and its risk factors in first-generation immigrant Asian Indians to the United States of America. Indian Heart J (1996) 3.66
Homocyst(e)ine and cardiovascular disease: a critical review of the epidemiologic evidence. Ann Intern Med (1999) 3.63
Epidemiology and causation of coronary heart disease and stroke in India. Heart (2008) 3.60
A number of different nuclear genes for the small subunit of RuBPCase are transcribed in petunia. Nucleic Acids Res (1983) 3.56
Health and peace: time for a new discipline. Lancet (2001) 3.52
Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome. Nature (1991) 3.43
Ramipril and the development of diabetes. JAMA (2001) 3.38
Effects of physiologic pacing versus ventricular pacing on the risk of stroke and death due to cardiovascular causes. Canadian Trial of Physiologic Pacing Investigators. N Engl J Med (2000) 3.32
Cardiovascular and cancer mortality among Canadians of European, south Asian and Chinese origin from 1979 to 1993: an analysis of 1.2 million deaths. CMAJ (1999) 3.18
Impact of diabetes on long-term prognosis in patients with unstable angina and non-Q-wave myocardial infarction: results of the OASIS (Organization to Assess Strategies for Ischemic Syndromes) Registry. Circulation (2000) 3.12
The treatment of portal hypertension: a meta-analytic review. Hepatology (1995) 3.11
The relationship between upper respiratory infections and hospital admissions for asthma: a time-trend analysis. Am J Respir Crit Care Med (1996) 3.10
The next ten years of health spending: what does the future hold? The Health Expenditures Projection Team. Health Aff (Millwood) (1998) 3.04
Stigmatization of AIDS patients by physicians. Am J Public Health (1987) 3.03
Use of polymerase chain reaction for diagnosis of picornavirus infection in subjects with and without respiratory symptoms. J Clin Microbiol (1993) 3.01
Hemodynamic events in a prospective randomized trial of propranolol versus placebo in the prevention of a first variceal hemorrhage. Gastroenterology (1990) 2.99
p53 Mutation and MDM2 amplification in human soft tissue sarcomas. Cancer Res (1993) 2.99
Surgical resection of hepatocellular carcinoma in cirrhotic patients: prognostic value of preoperative portal pressure. Gastroenterology (1996) 2.96
Effect of amlodipine on the progression of atherosclerosis and the occurrence of clinical events. PREVENT Investigators. Circulation (2000) 2.96
Clinical effects of anticoagulant therapy in suspected acute myocardial infarction: systematic overview of randomised trials. BMJ (1996) 2.90
Prevalence of coronary artery disease in Asian Indians. Am J Cardiol (1992) 2.90
Population pharmacokinetic analysis of the oral thrombin inhibitor dabigatran etexilate in patients with non-valvular atrial fibrillation from the RE-LY trial. J Thromb Haemost (2011) 2.87
Respiratory epithelial cell invasion by group B streptococci. Infect Immun (1992) 2.86
A randomised controlled trial of stress reduction for hypertension in older African Americans. Hypertension (1995) 2.85
Effects of intravenous magnesium in suspected acute myocardial infarction: overview of randomised trials. BMJ (1991) 2.81
TOPS: an internet-based system to prevent healthy subjects from over-volunteering for clinical trials. Eur J Clin Pharmacol (2012) 2.80
Assessment of the efficacy and effectiveness of influenza vaccines in healthy children: systematic review. Lancet (2005) 2.78
Health spending growth up in 1999; faster growth expected in the future. Health Aff (Millwood) (2001) 2.77
Glucose levels predict hospitalization for congestive heart failure in patients at high cardiovascular risk. Circulation (2007) 2.76
Two-step glutamate dehydrogenase antigen real-time polymerase chain reaction assay for detection of toxigenic Clostridium difficile. J Hosp Infect (2009) 2.76
Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice. Nat Genet (2001) 2.76
Unfractionated heparin and low-molecular-weight heparin in acute coronary syndrome without ST elevation: a meta-analysis. Lancet (2000) 2.74
Comparison of CT scan muscle measurements and isokinetic trunk strength in postoperative patients. Spine (Phila Pa 1976) (1989) 2.70
The action of substances allied to 4:4'-diaminodiphenylsulphone in streptococcal and other infections in mice. Biochem J (1938) 2.69
Determining the common medical presenting problems to an accident and emergency department. Arch Dis Child (2001) 2.67
DNA sequence of the rat growth hormone gene: location of the 5' terminus of the growth hormone mRNA and identification of an internal transposon-like element. Nucleic Acids Res (1981) 2.67
TRF1 is a dimer and bends telomeric DNA. EMBO J (1997) 2.64
Emerging role of angiotensin-converting enzyme inhibitors in cardiac and vascular protection. Circulation (1994) 2.61
Trithorax and dCBP acting in a complex to maintain expression of a homeotic gene. Science (2001) 2.61
Angiotensin II induces contraction and proliferation of human hepatic stellate cells. Gastroenterology (2000) 2.57
The care of HIV-infected adults in rural areas of the United States. J Acquir Immune Defic Syndr (2001) 2.34
The antioxidant vitamins and cardiovascular disease. A critical review of epidemiologic and clinical trial data. Ann Intern Med (1995) 2.32
Diagnostic accuracy of faecal occult blood tests used in screening for colorectal cancer: a systematic review. J Med Screen (2007) 2.30
Evaluation of the medical diagnostic imaging support system based on 2 years of clinical experience. J Digit Imaging (1995) 2.29
Calcium channel blockers in acute myocardial infarction and unstable angina: an overview. BMJ (1989) 2.27
Overview of randomised trials of diuretics in pregnancy. Br Med J (Clin Res Ed) (1985) 2.27
Risk factors for progression of brain atrophy in aging: six-year follow-up of normal subjects. Neurology (2005) 2.24