Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice.

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Published in Cardiovasc Diabetol on April 29, 2005

Authors

Jeanette Schultz Johansen1, Alex K Harris, David J Rychly, Adviye Ergul

Author Affiliations

1: University of Tromso, Tromso, Norway. jeajoh@student.uit.no

Associated clinical trials:

Acetylsalicylic Acid and Type 2 Diabetes Mellitus | NCT03341117

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Remote ischemic postconditioning: harnessing endogenous protection in a murine model of vascular cognitive impairment. Transl Stroke Res (2014) 0.91

Native matrix metalloproteinase characteristics may influence early stenosis of venous versus arterial coronary artery bypass grafting conduits. Chest (2004) 0.90

Activation of the ET-1/ETA pathway contributes to erectile dysfunction associated with mineralocorticoid hypertension. J Sex Med (2008) 0.90

Candesartan induces a prolonged proangiogenic effect and augments endothelium-mediated neuroprotection after oxygen and glucose deprivation: role of vascular endothelial growth factors A and B. J Pharmacol Exp Ther (2014) 0.90

Effects of spironolactone on cerebral vessel structure in rats with sustained hypertension. Am J Hypertens (2011) 0.89

Nox2-derived superoxide contributes to cerebral vascular dysfunction in diet-induced obesity. Stroke (2013) 0.88

Erectile dysfunction in young non-obese type II diabetic Goto-Kakizaki rats is associated with decreased eNOS phosphorylation at Ser1177. J Sex Med (2010) 0.88

Nuclear localization of endothelin-converting enzyme-1: subisoform specificity. Arterioscler Thromb Vasc Biol (2003) 0.88

Comparison of selective versus dual endothelin receptor antagonism on cerebrovascular dysfunction in diabetes. Neurol Res (2011) 0.87

Differential effects of diet-induced dyslipidemia and hyperglycemia on mesenteric resistance artery structure and function in type 2 diabetes. J Pharmacol Exp Ther (2008) 0.86

DOCA-salt treatment enhances responses to endothelin-1 in murine corpus cavernosum. Can J Physiol Pharmacol (2008) 0.85

Thioredoxin-interacting protein: a novel target for neuroprotection in experimental thromboembolic stroke in mice. Mol Neurobiol (2014) 0.85

Saphenous vein endothelin system expression and activity in African American patients. Arterioscler Thromb Vasc Biol (2002) 0.85

Interleukin-10 attenuates vascular responses to endothelin-1 via effects on ERK1/2-dependent pathway. Am J Physiol Heart Circ Physiol (2008) 0.84

Reduced endothelium-dependent relaxation to anandamide in mesenteric arteries from young obese Zucker rats. PLoS One (2013) 0.84

Low-dose candesartan enhances molecular mediators of neuroplasticity and subsequent functional recovery after ischemic stroke in rats. Mol Neurobiol (2014) 0.84

The effect of endothelin receptor A antagonism on basilar artery endothelium-dependent relaxation after ischemic stroke. Life Sci (2012) 0.84

Phosphorylation of endothelin converting enzyme-1 isoforms: relevance to subcellular localization. Exp Biol Med (Maywood) (2006) 0.83

Dual endothelin receptor antagonism prevents remodeling of resistance arteries in diabetes. Can J Physiol Pharmacol (2010) 0.83

Sepiapterin decreases vasorelaxation in nitric oxide synthase inhibition-induced hypertension. J Cardiovasc Pharmacol (2004) 0.82

Endothelin-1-mediated cerebrovascular remodeling is not associated with increased ischemic brain injury in diabetes. Can J Physiol Pharmacol (2010) 0.82

Candesartan reduces the hemorrhage associated with delayed tissue plasminogen activator treatment in rat embolic stroke. Neurochem Res (2013) 0.82

Internal pudendal artery from type 2 diabetic female rats demonstrate elevated endothelin-1-mediated constriction. J Sex Med (2011) 0.81

Comparative Analysis of Different Methods of Ischemia/Reperfusion in Hyperglycemic Stroke Outcomes: Interaction with tPA. Transl Stroke Res (2015) 0.81

Recommendations for preclinical research in hemorrhagic transformation. Transl Stroke Res (2013) 0.81

Peroxynitrite mediates testosterone-induced vasodilation of microvascular resistance vessels. J Pharmacol Exp Ther (2013) 0.79

Minocycline prevents IL-6 increase after acute ischemic stroke. Transl Stroke Res (2012) 0.79

Neuroprotection by tempol in a model of iron-induced oxidative stress in acute ischemic stroke. Am J Physiol Regul Integr Comp Physiol (2003) 0.79

Lacidipine has antiatherosclerotic effects independent of its actions on lipid metabolism and blood pressure. Vascul Pharmacol (2010) 0.77

Vascular endothelin converting enzyme-1 expression and activity is upregulated in clinical diabetes. Ethn Dis (2002) 0.77

Oxidative stress and cardiovascular risk in overweight children in an exercise intervention program. Child Obes (2012) 0.76

Augmented dilation to nitric oxide in uterine arteries from rats with type 2 diabetes: implications for vascular adaptations to pregnancy. Am J Physiol Heart Circ Physiol (2013) 0.76

Response to letter regarding article, "Remote ischemic perconditioning is effective alone and in combination with intravenous tissue-type". Stroke (2013) 0.75

Selective downregulation of endothelin-B receptors in diabetic African-American patients. Ethn Dis (2002) 0.75

Erratum to: Thioredoxin-interacting protein: a novel target for neuroprotection in experimental thromboembolic stroke in mice. Mol Neurobiol (2015) 0.75

Decreased vascular matrix metalloproteinase abundance in diabetic patients with symptomatic macroangiopathy. Ethn Dis (2002) 0.75