Published in Nature on January 25, 2001
Social feeding in Caenorhabditis elegans is induced by neurons that detect aversive stimuli. Nature (2002) 2.61
Peripheral mechanisms of neuropathic pain - involvement of lysophosphatidic acid receptor-mediated demyelination. Mol Pain (2008) 1.17
Neuropeptide Y, peptide YY and pancreatic polypeptide in the gut-brain axis. Neuropeptides (2012) 1.16
The neuropeptide Y Y1 receptor subtype is necessary for the anxiolytic-like effects of neuropeptide Y, but not the antidepressant-like effects of fluoxetine, in mice. Psychopharmacology (Berl) (2007) 1.14
Therapeutic potential of neuropeptide Y (NPY) receptor ligands. EMBO Mol Med (2010) 1.12
Intrathecal neuropeptide Y reduces behavioral and molecular markers of inflammatory or neuropathic pain. Pain (2007) 0.99
The Gut's Little Brain in Control of Intestinal Immunity. ISRN Gastroenterol (2013) 0.91
The neuropeptide neuromedin U promotes inflammation by direct activation of mast cells. J Exp Med (2005) 0.90
Neuropeptide Y(1) Receptor NPY1R discovery of naturally occurring human genetic variants governing gene expression in cella as well as pleiotropic effects on autonomic activity and blood pressure in vivo. J Am Coll Cardiol (2009) 0.87
A secretagogin locus of the mammalian hypothalamus controls stress hormone release. EMBO J (2014) 0.86
Genome-wide expression analysis of Ptf1a- and Ascl1-deficient mice reveals new markers for distinct dorsal horn interneuron populations contributing to nociceptive reflex plasticity. J Neurosci (2013) 0.85
Neuropeptide Y inhibits capsaicin-sensitive nociceptors via a Y1-receptor-mediated mechanism. Neuroscience (2004) 0.85
Behavioral and anatomical characterization of the bilateral sciatic nerve chronic constriction (bCCI) injury: correlation of anatomic changes and responses to cold stimuli. Mol Pain (2010) 0.82
The ability of neuropeptide Y to mediate responses in the murine cutaneous microvasculature: an analysis of the contribution of Y1 and Y2 receptors. Br J Pharmacol (2003) 0.82
Y1 receptor knockout increases nociception and prevents the anti-allodynic actions of NPY. Nutrition (2008) 0.82
Delayed stress-induced differences in locomotor and depression-related behaviour in female neuropeptide-Y Y1 receptor knockout mice. J Psychopharmacol (2009) 0.81
Neuropeptide Y modulates effects of bradykinin and prostaglandin E2 on trigeminal nociceptors via activation of the Y1 and Y2 receptors. Br J Pharmacol (2006) 0.80
RGS9-2--controlled adaptations in the striatum determine the onset of action and efficacy of antidepressants in neuropathic pain states. Proc Natl Acad Sci U S A (2015) 0.80
Inflammation enhances Y1 receptor signaling, neuropeptide Y-mediated inhibition of hyperalgesia, and substance P release from primary afferent neurons. Neuroscience (2013) 0.78
Neuropeptide Y inhibits axonal transport of particles in neurites of cultured adult mouse dorsal root ganglion cells. J Physiol (2002) 0.78
Calcitonin gene related peptide and neuropeptide Y in skeletal muscle after eccentric exercise: a microdialysis study. Br J Sports Med (2006) 0.77
Neuropeptide Y inhibits the trigeminovascular pathway through NPY Y1 receptor: implications for migraine. Pain (2016) 0.76
Localization of neuropeptide Y1 receptor immunoreactivity in the rat retina and the synaptic connectivity of Y1 immunoreactive cells. J Comp Neurol (2002) 0.76
Transmission pathways and mediators as the basis for clinical pharmacology of pain. Expert Rev Clin Pharmacol (2016) 0.75
Transcriptomic and behavioural characterisation of a mouse model of burn pain identify the cholecystokinin 2 receptor as an analgesic target. Mol Pain (2016) 0.75
Visceral hyperalgesia caused by peptide YY deletion and Y2 receptor antagonism. Sci Rep (2017) 0.75
5-HIAA in the cerebrospinal fluid. A biochemical suicide predictor? Arch Gen Psychiatry (1976) 3.15
Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A1 receptor. Proc Natl Acad Sci U S A (2001) 2.73
Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression. Nat Genet (1999) 2.57
Abnormal heart rate and body temperature in mice lacking thyroid hormone receptor alpha 1. EMBO J (1998) 2.45
Messenger plasticity in primary sensory neurons following axotomy and its functional implications. Trends Neurosci (1994) 2.44
Learning deficit in BDNF mutant mice. Eur J Neurosci (1997) 2.20
Effect of low- and high-frequency TENS on Met-enkephalin-Arg-Phe and dynorphin A immunoreactivity in human lumbar CSF. Pain (1991) 1.79
Role of cardiac vagal C-fibers in cardiovascular control. Rev Physiol Biochem Pharmacol (1979) 1.70
Increased activity in left ventricular receptors during hemorrhage or occlusion of caval veins in the cat. A possible cause of the vaso-vagal reaction. Acta Physiol Scand (1972) 1.61
Vascular endothelial growth factor-B-deficient mice display an atrial conduction defect. Circulation (2001) 1.57
Molecular cloning of rat trkC and distribution of cells expressing messenger RNAs for members of the trk family in the rat central nervous system. Neuroscience (1992) 1.52
Reduction of HIV transmission during laparoscopic procedures. Surg Laparosc Endosc (1993) 1.49
Granulocyte transfusions for treating infections in patients with neutropenia or neutrophil dysfunction. Cochrane Database Syst Rev (2005) 1.47
Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo. Nat Biotechnol (1998) 1.44
Sensory but not motor neuron deficits in mice lacking NT4 and BDNF. Nature (1995) 1.41
Differential dependency of cutaneous mechanoreceptors on neurotrophins, trk receptors, and P75 LNGFR. Dev Biol (1997) 1.40
Effects of intrathecal local anesthetics on spinal excitability and on the development of autotomy. Pain (1995) 1.40
Lingual deficits in BDNF and NT3 mutant mice leading to gustatory and somatosensory disturbances, respectively. Development (1997) 1.38
Localization of brain-derived neurotrophic factor mRNA to neurons in the brain by in situ hybridization. Exp Neurol (1990) 1.37
Increase of galanin-like immunoreactivity in rat dorsal root ganglion cells after peripheral axotomy. Neurosci Lett (1987) 1.34
Human T-cell tumours containing chromosome 14 inversion or translocation with breakpoints proximal to immunoglobulin joining regions at 14q32. EMBO J (1987) 1.32
Normal feeding behavior, body weight and leptin response require the neuropeptide Y Y2 receptor. Nat Med (1999) 1.31
Suppressed epileptogenesis in BDNF mutant mice. Exp Neurol (1995) 1.30
Cardiovascular phenotype and temperature control in mice lacking thyroid hormone receptor-beta or both alpha1 and beta. Am J Physiol (1999) 1.29
Differential dependency of unmyelinated and A delta epidermal and upper dermal innervation on neurotrophins, trk receptors, and p75LNGFR. Dev Biol (1998) 1.29
Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma. Proc Natl Acad Sci U S A (1992) 1.29
Hypercapnia and hypoxia: chemoreceptor-mediated control of locus coeruleus neurons and splanchnic, sympathetic nerves. Brain Res (1981) 1.28
Myocardial infarction mediated by endothelin receptor signaling in hypercholesterolemic mice. Proc Natl Acad Sci U S A (1999) 1.28
Differential regulation of mRNAs for GDNF and its receptors Ret and GDNFR alpha after sciatic nerve lesion in the mouse. Eur J Neurosci (1997) 1.26
Neuropeptide expression in rat dorsal root ganglion cells and spinal cord after peripheral nerve injury with special reference to galanin. Neuroscience (1989) 1.26
"Serotonin depression"--a biochemical subgroup within the affective disorders? Science (1976) 1.24
Studies on left ventricular receptors, signalling in non-medullated vagal afferents. Acta Physiol Scand (1972) 1.21
Early immunologic and virologic responses to highly active antiretroviral therapy and subsequent disease progression among HIV-infected injection drug users. AIDS Care (2007) 1.20
Environmental enrichment and the brain. Prog Brain Res (2002) 1.20
Nociceptin or antinociceptin: potent spinal antinociceptive effect of orphanin FQ/nociceptin in the rat. Neuroreport (1996) 1.19
Activation of inducible nitric oxide synthase/nitric oxide by curli fibers leads to a fall in blood pressure during systemic Escherichia coli infection in mice. J Infect Dis (2001) 1.19
Chronic gestational exposure to ethanol causes insulin and IGF resistance and impairs acetylcholine homeostasis in the brain. Cell Mol Life Sci (2006) 1.19
Characteristics of rat aortic baroreceptors with nonmedullated afferent nerve fibers. Circ Res (1977) 1.18
Identification of sensitive and specific avian influenza polymerase chain reaction methods through blind ring trials organized in the European Union. Avian Dis (2007) 1.17
Renal sympathetic activity in spontaneously hypertensive rats and normotensive controls, as studied by three different methods. Acta Physiol Scand (1984) 1.14
Colocalization of NGF binding sites, trk mRNA, and low-affinity NGF receptor mRNA in primary sensory neurons: responses to injury and infusion of NGF. J Neurosci (1992) 1.14
Increased production of the TrkB protein tyrosine kinase receptor after brain insults. Neuron (1993) 1.13
ADME evaluation in drug discovery. 5. Correlation of Caco-2 permeation with simple molecular properties. J Chem Inf Comput Sci (2004) 1.13
Evidence that decreased heart rate in thyroid hormone receptor-alpha1-deficient mice is an intrinsic defect. Am J Physiol (1998) 1.12
Cerebral asymmetry and handedness. Nature (1994) 1.11
The effect of treatment with Campath-1H in patients with autoimmune cytopenias. Br J Haematol (2001) 1.11
Hyperproduction, purification, and mechanism of action of the cytotoxic enterotoxin produced by Aeromonas hydrophila. Infect Immun (1997) 1.10
Clomipramine treatment of obsessive-compulsive disorder. I. A controlled clinical trial. Arch Gen Psychiatry (1980) 1.10
Differential influence of nerve growth factor on neuropeptide expression in vivo: a novel role in peptide suppression in adult sensory neurons. J Neurosci (1995) 1.10
Marked increase in nitric oxide synthase mRNA in rat dorsal root ganglia after peripheral axotomy: in situ hybridization and functional studies. Proc Natl Acad Sci U S A (1992) 1.10
Molecular and biochemical characterization of a heat-labile cytotonic enterotoxin from Aeromonas hydrophila. Microb Pathog (1996) 1.10
ADME evaluation in drug discovery. 4. Prediction of aqueous solubility based on atom contribution approach. J Chem Inf Comput Sci (2004) 1.09
Deprived of habitual running, rats downregulate BDNF and TrkB messages in the brain. Neurosci Res (1999) 1.08
Contraction and intracellular Ca(2+) handling in isolated skeletal muscle of rats with congestive heart failure. Circ Res (2001) 1.08
Long-lasting cardiovascular depression induced by acupuncture-like stimulation of the sciatic nerve in unanaesthetized spontaneously hypertensive rats. Brain Res (1982) 1.08
Renal and cardiovascular effects of acute and chronic administration of felodipine to SHR. Eur J Pharmacol (1985) 1.07
Expression of neuropeptide Y and neuropeptide Y (Y1) receptor mRNA in rat spinal cord and dorsal root ganglia following peripheral tissue inflammation. J Neurosci (1994) 1.07
Complementary roles of neurotrophin 3 and a N-methyl-D-aspartate antagonist in the protection of noise and aminoglycoside-induced ototoxicity. Proc Natl Acad Sci U S A (2000) 1.06
Galanin-mediated control of pain: enhanced role after nerve injury. Proc Natl Acad Sci U S A (1992) 1.06
Requirement of neurotrophin-3 for the survival of proliferating trigeminal ganglion progenitor cells. Development (1996) 1.05
Vomiting and reflex vagal relaxation of the stomach elicited from heart receptors in the cat. Acta Physiol Scand (1973) 1.05
M-15: high-affinity chimeric peptide that blocks the neuronal actions of galanin in the hippocampus, locus coeruleus, and spinal cord. Proc Natl Acad Sci U S A (1991) 1.05
Immunoreactive calcitonin gene-related peptide and substance P coexist in sensory neurons to the spinal cord and interact in spinal behavioral responses of the rat. Neurosci Lett (1984) 1.04
The systemic administration of local anaesthetics produces a selective depression of C-afferent fibre evoked activity in the spinal cord. Pain (1985) 1.04
Running and cocaine both upregulate dynorphin mRNA in medial caudate putamen. Eur J Neurosci (2000) 1.04
Locus coeruleus neurons and sympathetic nerves: activation by visceral afferents. Brain Res (1986) 1.03
A local action of neurotrophin-3 prevents the death of proliferating sensory neuron precursor cells. Neuron (1996) 1.03
Susceptibility of Schistosoma japonicum to praziquantel in China. Trop Med Int Health (2001) 1.03
Complementary and overlapping expression of Y1, Y2 and Y5 receptors in the developing and adult mouse nervous system. Neuroscience (1998) 1.02
Cell death in regenerating populations of neurons in BDNF mutant mice. Brain Res Mol Brain Res (2000) 1.02
Triglyceride-based microemulsion for intravenous administration of sparingly soluble substances. J Pharm Sci (1998) 1.01
Nitric oxide synthase-like immunoreactivity in lumbar dorsal root ganglia and spinal cord of rat and monkey and effect of peripheral axotomy. J Comp Neurol (1993) 1.01
Activation of vagal depressor reflexes by atriopeptins inhibits renal sympathetic nerve activity. Am J Physiol (1986) 1.01
[Phe1psi(CH2-NH)Gly2]-nociceptin-(1-13)NH2, a proposed antagonist of the nociceptin receptor, is a potent and stable agonist in the rat spinal cord. Neurosci Lett (1998) 1.01
Left ventricular receptors activated by severe asphyxia and by coronary artery occlusion. Acta Physiol Scand (1972) 1.01
Prenatal and postnatal requirements of NT-3 for sympathetic neuroblast survival and innervation of specific targets. Development (1996) 1.00
Expression of either the TCL1 oncogene, or transcripts from its homologue MTCP1/c6.1B, in leukaemic and non-leukaemic T cells from ataxia telangiectasia patients. Oncogene (1996) 1.00
Hippocampal damage and kainic acid injection induce a rapid increase in mRNA for BDNF and NGF in the rat brain. Exp Neurol (1991) 1.00
Positive and negative interactions of GDNF, NTN and ART in developing sensory neuron subpopulations, and their collaboration with neurotrophins. Development (2000) 1.00
Chronic pain-related syndrome in rats after ischemic spinal cord lesion: a possible animal model for pain in patients with spinal cord injury. Pain (1992) 1.00
Regulation of neurotrophin and trkA, trkB and trkC tyrosine kinase receptor messenger RNA expression in kindling. Neuroscience (1993) 1.00
Spinal substance P and N-methyl-D-aspartate receptors are coactivated in the induction of central sensitization of the nociceptive flexor reflex. Neuroscience (1992) 0.99
Repeated measurements of cerebral blood flow in rats. Comparisons between the hydrogen clearance method and laser Doppler flowmetry. Acta Physiol Scand (1988) 0.98
Ethanol inhibits insulin expression and actions in the developing brain. Cell Mol Life Sci (2005) 0.98
Differential control of adrenal and renal sympathetic nerve activity during hemorrhagic hypotension in rats. Circ Res (1989) 0.98
BDNF regulates reelin expression and Cajal-Retzius cell development in the cerebral cortex. Neuron (1998) 0.98
Nociceptive responses in interleukin-6-deficient mice to peripheral inflammation and peripheral nerve section. Cytokine (1997) 0.98
Decreased inflammatory pain due to reduced carrageenan-induced inflammation in mice lacking adenosine A3 receptors. Neuroscience (2002) 0.97