Hemicentin, a conserved extracellular member of the immunoglobulin superfamily, organizes epithelial and other cell attachments into oriented line-shaped junctions.

PubWeight™: 1.65‹?› | Rank: Top 3%

🔗 View Article (PMID 11222143)

Published in Development on March 01, 2001

Authors

B E Vogel1, E M Hedgecock

Author Affiliations

1: Department of Biology, Johns Hopkins University, Baltimore, MD 21218, USA. vogel@umbi.umd.edu

Articles citing this

Distribution and evolution of von Willebrand/integrin A domains: widely dispersed domains with roles in cell adhesion and elsewhere. Mol Biol Cell (2002) 4.27

Dissection of genomewide-scan data in extended families reveals a major locus and oligogenic susceptibility for age-related macular degeneration. Am J Hum Genet (2003) 2.92

Genome-wide RNAi analysis of JAK/STAT signaling components in Drosophila. Genes Dev (2005) 2.63

Fibulins: physiological and disease perspectives. EMBO Rep (2003) 2.56

Genetic factors of age-related macular degeneration. Prog Retin Eye Res (2004) 2.17

Extracellular matrix molecules: potential targets in pharmacotherapy. Pharmacol Rev (2009) 1.90

A secreted protein promotes cleavage furrow maturation during cytokinesis. Curr Biol (2011) 1.88

Mechanosensation. WormBook (2006) 1.49

The cell biology of touch. J Cell Biol (2010) 1.45

Touch sensitivity in Caenorhabditis elegans. Pflugers Arch (2007) 1.38

Genetic analysis of age-dependent defects of the Caenorhabditis elegans touch receptor neurons. Proc Natl Acad Sci U S A (2011) 1.28

Genetic analysis of fin development in zebrafish identifies furin and hemicentin1 as potential novel fraser syndrome disease genes. PLoS Genet (2010) 1.25

The C. elegans peroxidasin PXN-2 is essential for embryonic morphogenesis and inhibits adult axon regeneration. Development (2010) 1.24

A ZYG-12-dynein interaction at the nuclear envelope defines cytoskeletal architecture in the C. elegans gonad. J Cell Biol (2009) 1.23

Mechanical control of the sense of touch by β-spectrin. Nat Cell Biol (2014) 1.14

Fibulin-5, an integrin-binding matricellular protein: its function in development and disease. J Cell Commun Signal (2009) 1.11

Cell invasion through basement membrane: the anchor cell breaches the barrier. Curr Opin Cell Biol (2011) 1.11

Coral transcriptome and bacterial community profiles reveal distinct Yellow Band Disease states in Orbicella faveolata. ISME J (2014) 1.07

Pyrosequencing-based expression profiling and identification of differentially regulated genes from Manduca sexta, a lepidopteran model insect. Insect Biochem Mol Biol (2011) 1.06

Modulation of C. elegans touch sensitivity is integrated at multiple levels. J Neurosci (2014) 1.05

The Caenorhabditis elegans epidermis as a model skin. II: differentiation and physiological roles. Wiley Interdiscip Rev Dev Biol (2012) 1.02

Redefining metamorphosis in spiny lobsters: molecular analysis of the phyllosoma to puerulus transition in Sagmariasus verreauxi. Sci Rep (2015) 1.00

Discovery and characterization of novel vascular and hematopoietic genes downstream of etsrp in zebrafish. PLoS One (2009) 0.98

C. elegans germ cells show temperature and age-dependent expression of Cer1, a Gypsy/Ty3-related retrotransposon. PLoS Pathog (2012) 0.96

Hemicentin 2 and Fibulin 1 are required for epidermal-dermal junction formation and fin mesenchymal cell migration during zebrafish development. Dev Biol (2012) 0.95

Structural basis for the high-affinity interaction of nidogen-1 with immunoglobulin-like domain 3 of perlecan. EMBO J (2001) 0.92

An active role for basement membrane assembly and modification in tissue sculpting. J Cell Sci (2015) 0.87

B-LINK: a hemicentin, plakin, and integrin-dependent adhesion system that links tissues by connecting adjacent basement membranes. Dev Cell (2014) 0.87

The C. elegans tailless/Tlx homolog nhr-67 regulates a stage-specific program of linker cell migration in male gonadogenesis. Development (2009) 0.86

Patient-to-patient variability in autologous pericardial matrix scaffolds for cardiac repair. J Cardiovasc Transl Res (2011) 0.85

The transcription factor HLH-2/E/Daughterless regulates anchor cell invasion across basement membrane in C. elegans. Dev Biol (2011) 0.84

Invadopodia and basement membrane invasion in vivo. Cell Adh Migr (2014) 0.83

Physiological change under OsHV-1 contamination in Pacific oyster Crassostrea gigas through massive mortality events on fields. BMC Genomics (2013) 0.83

Laser capture microdissection enables cellular and molecular studies of tooth root development. Int J Oral Sci (2012) 0.83

Tissue-specific transcriptomics and proteomics of a filarial nematode and its Wolbachia endosymbiont. BMC Genomics (2015) 0.83

Liver-specific NG37 overexpression leads to diet-dependent fatty liver disease accompanied by cardiac dysfunction. Genes Nutr (2016) 0.82

Analysis of the basal chordate Botryllus schlosseri reveals a set of genes associated with fertility. BMC Genomics (2014) 0.82

Genetics of extracellular matrix remodeling during organ growth using the Caenorhabditis elegans pharynx model. Genetics (2010) 0.82

The twisted pharynx phenotype in C. elegans. BMC Dev Biol (2007) 0.81

Specific structure and unique function define the hemicentin. Cell Biosci (2013) 0.80

A new job for ancient extracellular matrix proteins: Hemicentins stabilize cleavage furrows. Commun Integr Biol (2011) 0.79

Gonad morphogenesis defects drive hybrid male sterility in asymmetric hybrid breakdown of Caenorhabditis nematodes. Evol Dev (2014) 0.79

Aging in the nervous system of Caenorhabditis elegans. Commun Integr Biol (2013) 0.77

Natural reversal of left-right gut/gonad asymmetry in C. elegans males is independent of embryonic chirality. Genesis (2014) 0.77

Protein-Trap Insertional Mutagenesis Uncovers New Genes Involved in Zebrafish Skin Development, Including a Neuregulin 2a-Based ErbB Signaling Pathway Required during Median Fin Fold Morphogenesis. PLoS One (2015) 0.77

An extracellular matrix protein prevents cytokinesis failure and aneuploidy in the C. elegans germline. Cell Cycle (2011) 0.77

Basement Membranes in the Worm: A Dynamic Scaffolding that Instructs Cellular Behaviors and Shapes Tissues. Curr Top Membr (2015) 0.76

Genome-wide linkage and exome analyses identify variants of HMCN1 for splenic epidermoid cyst. BMC Med Genet (2014) 0.75

Genetic defects in β-spectrin and tau sensitize C. elegans axons to movement-induced damage via torque-tension coupling. Elife (2017) 0.75

Fibulin-6 regulates pro-fibrotic TGF-β responses in neonatal mouse ventricular cardiac fibroblasts. Sci Rep (2017) 0.75

Articles by these authors

Mutant sensory cilia in the nematode Caenorhabditis elegans. Dev Biol (1986) 7.71

Kinesin-related gene unc-104 is required for axonal transport of synaptic vesicles in C. elegans. Cell (1991) 4.78

cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family. Cell (1996) 4.11

Axonal guidance mutants of Caenorhabditis elegans identified by filling sensory neurons with fluorescein dyes. Dev Biol (1985) 3.98

Normal and mutant thermotaxis in the nematode Caenorhabditis elegans. Proc Natl Acad Sci U S A (1975) 3.76

Mutations affecting programmed cell deaths in the nematode Caenorhabditis elegans. Science (1983) 3.23

daf-12 encodes a nuclear receptor that regulates the dauer diapause and developmental age in C. elegans. Genes Dev (2000) 3.03

UNC-40, a C. elegans homolog of DCC (Deleted in Colorectal Cancer), is required in motile cells responding to UNC-6 netrin cues. Cell (1996) 2.78

UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans. Neuron (1992) 2.54

Limitation of the size of the vulval primordium of Caenorhabditis elegans by lin-15 expression in surrounding hypodermis. Nature (1990) 2.16

Neuroglia and pioneer neurons express UNC-6 to provide global and local netrin cues for guiding migrations in C. elegans. Neuron (1996) 2.14

UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans. Cell (1992) 2.12

daf-12 regulates developmental age and the dauer alternative in Caenorhabditis elegans. Development (1998) 1.98

Conservation and novelty in the evolution of cell adhesion and extracellular matrix genes. Science (2000) 1.93

Polyploid tissues in the nematode Caenorhabditis elegans. Dev Biol (1985) 1.59

Regulation of the UNC-5 netrin receptor initiates the first reorientation of migrating distal tip cells in Caenorhabditis elegans. Development (2000) 1.31

Cystic canal mutants in Caenorhabditis elegans are defective in the apical membrane domain of the renal (excretory) cell. Dev Biol (1999) 1.18

Fragile skeletal muscle attachments in dystrophic mutants of Caenorhabditis elegans: isolation and characterization of the mua genes. Development (2000) 1.17

The C. elegans F-box/WD-repeat protein LIN-23 functions to limit cell division during development. Development (2000) 1.13

A gene required for nuclear and mitochondrial attachment in the nematode Caenorhabditis elegans. Cell (1982) 1.03

Role of netrin UNC-6 in patterning the longitudinal nerves of Caenorhabditis elegans. J Neurobiol (1999) 0.99

mua-3, a gene required for mechanical tissue integrity in Caenorhabditis elegans, encodes a novel transmembrane protein of epithelial attachment complexes. J Cell Biol (2001) 0.94

Guidance of neuroblast migrations and axonal projections in Caenorhabditis elegans. Curr Opin Neurobiol (1992) 0.88

Hierarchical guidance cues in the developing nervous system of C. elegans. Bioessays (1996) 0.82

Identification of epi-1 locus as a laminin alpha chain gene in the nematode Caenorhabditis elegans and characterization of epi-1 mutant alleles. DNA Seq (1999) 0.80