Published in Nat Rev Genet on January 01, 2001
Fast and reliable prediction of noncoding RNAs. Proc Natl Acad Sci U S A (2005) 8.15
A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains. BMC Genomics (2007) 6.28
Lessons from X-chromosome inactivation: long ncRNA as guides and tethers to the epigenome. Genes Dev (2009) 4.20
The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome. Science (2013) 4.12
A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced. Genes Dev (2006) 3.41
NONCODE: an integrated knowledge database of non-coding RNAs. Nucleic Acids Res (2005) 3.16
Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse. EMBO J (2003) 2.94
Pan-S replication patterns and chromosomal domains defined by genome-tiling arrays of ENCODE genomic areas. Genome Res (2007) 2.82
Mammalian microRNAs: a small world for fine-tuning gene expression. Mamm Genome (2006) 2.64
Long-range chromosomal interactions and gene regulation. Mol Biosyst (2008) 2.56
The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting. Nature (2009) 2.40
High- and low-mobility populations of HP1 in heterochromatin of mammalian cells. Mol Biol Cell (2004) 2.29
The epigenetics of sex differences in the brain. J Neurosci (2009) 2.25
The role of histone H2Av variant replacement and histone H4 acetylation in the establishment of Drosophila heterochromatin. Genes Dev (2005) 2.09
A longitudinal study of epigenetic variation in twins. Epigenetics (2010) 2.06
Comparative sequence analysis of the X-inactivation center region in mouse, human, and bovine. Genome Res (2002) 2.04
Epigenetics and human disease: translating basic biology into clinical applications. CMAJ (2006) 1.98
The Polycomb group protein Eed protects the inactive X-chromosome from differentiation-induced reactivation. Nat Cell Biol (2006) 1.97
Three-dimensional arrangements of centromeres and telomeres in nuclei of human and murine lymphocytes. Chromosome Res (2003) 1.94
Origin of sphinx, a young chimeric RNA gene in Drosophila melanogaster. Proc Natl Acad Sci U S A (2002) 1.92
Stress-induced transcription of satellite III repeats. J Cell Biol (2003) 1.86
Antisense transcription through the Xist locus mediates Tsix function in embryonic stem cells. Mol Cell Biol (2001) 1.86
Multiple spatially distinct types of facultative heterochromatin on the human inactive X chromosome. Proc Natl Acad Sci U S A (2004) 1.80
Experimental approaches to identify non-coding RNAs. Nucleic Acids Res (2006) 1.80
Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells. RNA (2009) 1.78
X chromosomes alternate between two states prior to random X-inactivation. PLoS Biol (2006) 1.66
Random monoallelic expression of three genes clustered within 60 kb of mouse t complex genomic DNA. Genome Res (2001) 1.56
Evidence of influence of genomic DNA sequence on human X chromosome inactivation. PLoS Comput Biol (2006) 1.52
Indirect effects of ploidy suggest X chromosome dose, not the X:A ratio, signals sex in Drosophila. PLoS Biol (2007) 1.51
Analysis and accurate quantification of CpG methylation by MALDI mass spectrometry. Nucleic Acids Res (2003) 1.46
Two-step imprinted X inactivation: repeat versus genic silencing in the mouse. Mol Cell Biol (2010) 1.46
The X as model for RNA's niche in epigenomic regulation. Cold Spring Harb Perspect Biol (2010) 1.43
Dynamic histone modifications mark sex chromosome inactivation and reactivation during mammalian spermatogenesis. Proc Natl Acad Sci U S A (2004) 1.41
The mouse Murr1 gene is imprinted in the adult brain, presumably due to transcriptional interference by the antisense-oriented U2af1-rs1 gene. Mol Cell Biol (2004) 1.40
Cell cycle-dependent localization of macroH2A in chromatin of the inactive X chromosome. J Cell Biol (2002) 1.36
RNA-protein interactions in human health and disease. Semin Cell Dev Biol (2011) 1.35
Imprinted silencing of Slc22a2 and Slc22a3 does not need transcriptional overlap between Igf2r and Air. EMBO J (2003) 1.32
Reporting of sex as a variable in cardiovascular studies using cultured cells. Biol Sex Differ (2011) 1.32
X chromosome inactivation is initiated in human preimplantation embryos. Am J Hum Genet (2009) 1.31
Dicer regulates Xist promoter methylation in ES cells indirectly through transcriptional control of Dnmt3a. Epigenetics Chromatin (2008) 1.30
Identification of developmentally specific enhancers for Tsix in the regulation of X chromosome inactivation. Mol Cell Biol (2005) 1.30
The promoter of the Chinese hamster ovary dihydrofolate reductase gene regulates the activity of the local origin and helps define its boundaries. Genes Dev (2004) 1.30
Noncoding regulatory RNAs database. Nucleic Acids Res (2003) 1.29
The Air noncoding RNA: an imprinted cis-silencing transcript. Cold Spring Harb Symp Quant Biol (2004) 1.27
The Xist RNA A-repeat comprises a novel AUCG tetraloop fold and a platform for multimerization. RNA (2011) 1.26
Functional redundancy within roX1, a noncoding RNA involved in dosage compensation in Drosophila melanogaster. Genetics (2003) 1.24
A review of the role of female gender in autism spectrum disorders. J Autism Dev Disord (2013) 1.24
New twists in X-chromosome inactivation. Curr Opin Cell Biol (2008) 1.22
The development of an Arabidopsis model system for genome-wide analysis of polyploidy effects. Biol J Linn Soc Lond (2004) 1.22
A boundary element between Tsix and Xist binds the chromatin insulator Ctcf and contributes to initiation of X-chromosome inactivation. Genetics (2011) 1.20
The yin and yang of chromatin spatial organization. Genome Biol (2010) 1.20
Differential methylation of Xite and CTCF sites in Tsix mirrors the pattern of X-inactivation choice in mice. Mol Cell Biol (2006) 1.20
Nonrandom representation of sex-biased genes on chicken Z chromosome. J Mol Evol (2006) 1.16
Epigenetic regulation in mammalian preimplantation embryo development. Reprod Biol Endocrinol (2009) 1.15
The A-repeat links ASF/SF2-dependent Xist RNA processing with random choice during X inactivation. Nat Struct Mol Biol (2010) 1.14
X chromosome choice occurs independently of asynchronous replication timing. J Cell Biol (2005) 1.14
Domain regulation of imprinting cluster in Kip2/Lit1 subdomain on mouse chromosome 7F4/F5: large-scale DNA methylation analysis reveals that DMR-Lit1 is a putative imprinting control region. Genome Res (2002) 1.13
Autoimmunity and Klinefelter's syndrome: when men have two X chromosomes. J Autoimmun (2009) 1.10
RNA is an integral component of chromatin that contributes to its structural organization. PLoS One (2007) 1.10
Skewing X chromosome choice by modulating sense transcription across the Xist locus. Genes Dev (2003) 1.09
Early loss of Xist RNA expression and inactive X chromosome associated chromatin modification in developing primordial germ cells. PLoS One (2007) 1.08
Sex, dose, and equality. PLoS Biol (2007) 1.07
Sex-biased methylome and transcriptome in human prefrontal cortex. Hum Mol Genet (2013) 1.06
Self-assembly and DNA binding of the blocking factor in x chromosome inactivation. PLoS Comput Biol (2007) 1.04
Exploring alternative models for sex-linked quantitative trait loci in outbred populations: application to an iberian x landrace pig intercross. Genetics (2002) 1.03
The epigenome of evolving Drosophila neo-sex chromosomes: dosage compensation and heterochromatin formation. PLoS Biol (2013) 1.03
Histone variant macroH2A contains two distinct macrochromatin domains capable of directing macroH2A to the inactive X chromosome. Nucleic Acids Res (2001) 1.03
Sex/gender medicine. The biological basis for personalized care in cardiovascular medicine. Circ J (2009) 1.01
Statistical signals in bioinformatics. Proc Natl Acad Sci U S A (2005) 1.01
Activity map of the tammar X chromosome shows that marsupial X inactivation is incomplete and escape is stochastic. Genome Biol (2010) 1.00
First-generation linkage map of the gray, short-tailed opossum, Monodelphis domestica, reveals genome-wide reduction in female recombination rates. Genetics (2004) 0.98
Transcription precedes loss of Xist coating and depletion of H3K27me3 during X-chromosome reprogramming in the mouse inner cell mass. Development (2011) 0.98
Pluripotency factor binding and Tsix expression act synergistically to repress Xist in undifferentiated embryonic stem cells. Epigenetics Chromatin (2011) 0.97
Restricted chromosomal silencing in nucleolar dominance. Proc Natl Acad Sci U S A (2001) 0.97
Epigenetic effects of endocrine-disrupting chemicals on female reproduction: an ovarian perspective. Front Neuroendocrinol (2010) 0.97
Beyond the proteome: non-coding regulatory RNAs. Genome Biol (2002) 0.96
A Primary Role for the Tsix lncRNA in Maintaining Random X-Chromosome Inactivation. Cell Rep (2015) 0.95
Expression of the disease on female carriers of X-linked lysosomal disorders: a brief review. Orphanet J Rare Dis (2010) 0.93
A longitudinal twin study of skewed X chromosome-inactivation. PLoS One (2011) 0.93
Retinoic acid accelerates downregulation of the Xist repressor, Oct4, and increases the likelihood of Xist activation when Tsix is deficient. BMC Dev Biol (2010) 0.92
Conformation regulation of the X chromosome inactivation center: a model. PLoS Comput Biol (2011) 0.92
Non-coding RNAs revealed during identification of genes involved in chicken immune responses. Immunogenetics (2008) 0.91
A Functional chromatin domain does not resist X chromosome inactivation: silencing of cLys correlates with methylation of a dual promoter-replication origin. Mol Cell Biol (2002) 0.89
Aberrant allele-specific replication, independent of parental origin, in blood cells of cancer patients. BMC Cancer (2008) 0.89
Viability of X-autosome translocations in mammals: an epigenomic hypothesis from a rodent case-study. Chromosoma (2004) 0.88
Should there be sex-specific criteria for the diagnosis and treatment of heart failure? J Cardiovasc Transl Res (2013) 0.87
Sex differences in DNA methylation assessed by 450 K BeadChip in newborns. BMC Genomics (2015) 0.87
Nuclear stress granules: the awakening of a sleeping beauty? J Cell Biol (2004) 0.87
An N-ethyl-N-nitrosourea mutagenesis screen for epigenetic mutations in the mouse. Genetics (2003) 0.87
Imaging Specific Genomic DNA in Living Cells. Annu Rev Biophys (2016) 0.86
Computational and experimental approaches to reveal the effects of single nucleotide polymorphisms with respect to disease diagnostics. Int J Mol Sci (2014) 0.86
Mechanics and dynamics of X-chromosome pairing at X inactivation. PLoS Comput Biol (2008) 0.85
Strategies and methods to study sex differences in cardiovascular structure and function: a guide for basic scientists. Biol Sex Differ (2011) 0.84
RNACompress: Grammar-based compression and informational complexity measurement of RNA secondary structure. BMC Bioinformatics (2008) 0.84
Association of BRCA1 with the inactive X chromosome and XIST RNA. Philos Trans R Soc Lond B Biol Sci (2004) 0.83
X marks the spot: does it matter that O-GlcNAc transferase is an X-linked gene? Biochem Biophys Res Commun (2014) 0.82
A novel statistical approach for jointly analyzing RNA-Seq data from F1 reciprocal crosses and inbred lines. Genetics (2014) 0.82
Human X chromosome inactivation and reactivation: implications for cell reprogramming and disease. Philos Trans R Soc Lond B Biol Sci (2017) 0.81
Impact of epigenetic dietary compounds on transgenerational prevention of human diseases. AAPS J (2013) 0.81
Skewed X chromosome inactivation and early-onset breast cancer. J Med Genet (2005) 0.81
Sensing X chromosome pairs before X inactivation via a novel X-pairing region of the Xic. Science (2007) 1.83
Functional analysis of the DXPas34 locus, a 3' regulator of Xist expression. Mol Cell Biol (1999) 1.48
Integrated kinetics of X chromosome inactivation in differentiating embryonic stem cells. Cytogenet Genome Res (2002) 1.42
Xce haplotypes show modified methylation in a region of the active X chromosome lying 3' to Xist. Proc Natl Acad Sci U S A (1995) 1.37
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A developmental switch in H4 acetylation upstream of Xist plays a role in X chromosome inactivation. EMBO J (1999) 1.13
Molecular correlates of the murine Xce locus. Genet Res (1998) 1.07
Cloning and localization of the murine Xpct gene: evidence for complex rearrangements during the evolution of the region around the Xist gene. Genomics (1998) 1.05
Chromatin structure and nuclear organization dynamics during X-chromosome inactivation. Cold Spring Harb Symp Quant Biol (2011) 1.00
Nonrigid registration of 3-d multichannel microscopy images of cell nuclei. IEEE Trans Image Process (2008) 0.96
Cdyl, a new partner of the inactive X chromosome and potential reader of H3K27me3 and H3K9me2. Mol Cell Biol (2013) 0.92
The dynamics of imprinted X inactivation during preimplantation development in mice. Cytogenet Genome Res (2006) 0.90
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