Published in Science on March 23, 2001
Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. PLoS Biol (2004) 9.38
Associating genes with gene ontology codes using a maximum entropy analysis of biomedical literature. Genome Res (2002) 3.77
Integration of text- and data-mining using ontologies successfully selects disease gene candidates. Nucleic Acids Res (2005) 2.46
Defrosting the digital library: bibliographic tools for the next generation web. PLoS Comput Biol (2008) 1.88
Using text analysis to identify functionally coherent gene groups. Genome Res (2002) 1.71
Information technology and telemedicine. CMAJ (2001) 0.86
Science's response. Is a government archive the best option? Science (2001) 0.86
For free access, follow the brick red buttons. Science (2001) 0.75
Considerations in creating online archives. Science (2001) 0.75
2005 Curt Stern Award address. Exploring along a crooked path. Am J Hum Genet (2006) 0.75
Publishers. Bull Med Libr Assoc (2001) 0.75
Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci U S A (1998) 192.97
Molecular portraits of human breast tumours. Nature (2000) 94.14
Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science (1995) 88.48
The genome sequence of Drosophila melanogaster. Science (2000) 74.32
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A (2001) 71.82
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature (2000) 64.32
Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization. Mol Biol Cell (1998) 62.20
Exploring the metabolic and genetic control of gene expression on a genomic scale. Science (1997) 60.15
The Gene Ontology (GO) database and informatics resource. Nucleic Acids Res (2004) 54.37
The transcriptional program of sporulation in budding yeast. Science (1998) 37.23
Genomic expression programs in the response of yeast cells to environmental changes. Mol Biol Cell (2000) 36.09
Comparative genomics of the eukaryotes. Science (2000) 26.62
Systematic variation in gene expression patterns in human cancer cell lines. Nat Genet (2000) 24.22
Parallel human genome analysis: microarray-based expression monitoring of 1000 genes. Proc Natl Acad Sci U S A (1996) 24.18
Functional annotation of a full-length mouse cDNA collection. Nature (2001) 23.61
A DNA microarray system for analyzing complex DNA samples using two-color fluorescent probe hybridization. Genome Res (1996) 23.16
Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF. Nature (2001) 21.55
Transformation of mammalian cells with genes from procaryotes and eucaryotes. Cell (1979) 21.15
Dynamic instability of microtubule growth. Nature (1984) 20.32
The transcriptional program in the response of human fibroblasts to serum. Science (1999) 19.19
Singular value decomposition for genome-wide expression data processing and modeling. Proc Natl Acad Sci U S A (2000) 18.42
Diversity of gene expression in adenocarcinoma of the lung. Proc Natl Acad Sci U S A (2001) 17.36
Use of a cDNA microarray to analyse gene expression patterns in human cancer. Nat Genet (1996) 15.73
The induction of gene activity in drosophilia by heat shock. Cell (1979) 15.17
Genome-wide analysis of DNA copy-number changes using cDNA microarrays. Nat Genet (1999) 14.96
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Proc Natl Acad Sci U S A (1999) 14.16
One-stop shop for microarray data. Nature (2000) 13.54
Mapping unintegrated avian sarcoma virus DNA: termini of linear DNA bear 300 nucleotides present once or twice in two species of circular DNA. Cell (1978) 13.33
A gene expression database for the molecular pharmacology of cancer. Nat Genet (2000) 13.31
Promoter-specific binding of Rap1 revealed by genome-wide maps of protein-DNA association. Nat Genet (2001) 13.05
Wnt signaling: a common theme in animal development. Genes Dev (1997) 12.94
DNA arrays for analysis of gene expression. Methods Enzymol (1999) 12.50
Gene expression informatics--it's all in your mine. Nat Genet (1999) 12.35
The molecular biology of the hepatitis B viruses. Annu Rev Biochem (1987) 12.32
Evidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoprotein. Cell (1978) 11.17
In vivo footprinting of a muscle specific enhancer by ligation mediated PCR. Science (1989) 10.87
Correct integration of retroviral DNA in vitro. Cell (1987) 10.73
Characterization of ribosomal frameshifting in HIV-1 gag-pol expression. Nature (1988) 10.69
Beyond self-assembly: from microtubules to morphogenesis. Cell (1986) 10.53
DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA. Nature (1976) 9.81
Drug target validation and identification of secondary drug target effects using DNA microarrays. Nat Med (1998) 9.72
Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science (1984) 9.64
Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome. Cell (1982) 9.29
Mechanisms of Wnt signaling in development. Annu Rev Cell Dev Biol (1998) 9.24
Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas. Nature (1982) 9.12
A major developmental transition in early Xenopus embryos: I. characterization and timing of cellular changes at the midblastula stage. Cell (1982) 9.11
Form and function of retroviral proviruses. Science (1982) 8.80
A nucleoprotein complex mediates the integration of retroviral DNA. Genes Dev (1989) 8.80
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour. Nature (1983) 8.18
Microtubule assembly nucleated by isolated centrosomes. Nature (1984) 8.15
Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein. Proc Natl Acad Sci U S A (1989) 8.13
Gaussian models for genetic linkage analysis using complete high-resolution maps of identity by descent. Am J Hum Genet (1993) 8.05
The Stanford Microarray Database. Nucleic Acids Res (2001) 7.77
Integration of murine leukemia virus DNA depends on mitosis. EMBO J (1993) 7.62
Uninfected vertebrate cells contain a protein that is closely related to the product of the avian sarcoma virus transforming gene (src). Proc Natl Acad Sci U S A (1979) 7.55
Proviruses of avian sarcoma virus are terminally redundant, co-extensive with unintegrated linear DNA and integrated at many sites. Cell (1978) 7.46
Genomic sequencing and methylation analysis by ligation mediated PCR. Science (1989) 7.38
Molecular cloning and characterization of avian sarcoma virus circular DNA molecules. J Virol (1980) 7.37
Signals for ribosomal frameshifting in the Rous sarcoma virus gag-pol region. Cell (1988) 7.14
A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature (1996) 7.04
A methodology to migrate the gene ontology to a description logic environment using DAML+OIL. Pac Symp Biocomput (2003) 7.04
Birth of the D-E-A-D box. Nature (1989) 7.02
Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma. Proc Natl Acad Sci U S A (1983) 7.01
Analysis of avian leukosis virus DNA and RNA in bursal tumours: viral gene expression is not required for maintenance of the tumor state. Cell (1981) 6.98
The messenger RNA for alcohol dehydrogenase in Drosophila melanogaster differs in its 5' end in different developmental stages. Cell (1983) 6.84
Weight-supported treadmill vs over-ground training for walking after acute incomplete SCI. Neurology (2006) 6.66
Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. Cell (1988) 6.48
Genomic expression responses to DNA-damaging agents and the regulatory role of the yeast ATR homolog Mec1p. Mol Biol Cell (2001) 6.39
Energy coupling in DNA gyrase and the mechanism of action of novobiocin. Proc Natl Acad Sci U S A (1978) 6.33
Comparative gene expression profiles following UV exposure in wild-type and SOS-deficient Escherichia coli. Genetics (2001) 6.29
mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2. Cell (1991) 6.25
Structure and variability of human chromosome ends. Mol Cell Biol (1990) 6.18
Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication. Cell (1990) 6.17
Delineating developmental and metabolic pathways in vivo by expression profiling using the RIKEN set of 18,816 full-length enriched mouse cDNA arrays. Proc Natl Acad Sci U S A (2001) 6.07
Sites of microtubule assembly and disassembly in the mitotic spindle. Cell (1986) 5.91
Expression of the Rous sarcoma virus pol gene by ribosomal frameshifting. Science (1985) 5.90
A mutant murine leukemia virus with a single missense codon in pol is defective in a function affecting integration. Proc Natl Acad Sci U S A (1984) 5.81
The molecular genetics of cellular oncogenes. Annu Rev Genet (1984) 5.72
Polymerase gene products of hepatitis B viruses are required for genomic RNA packaging as wel as for reverse transcription. Nature (1990) 5.68
Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes. Genes Dev (2001) 5.67
Yeast microarrays for genome wide parallel genetic and gene expression analysis. Proc Natl Acad Sci U S A (1997) 5.59
Global mapping of meiotic recombination hotspots and coldspots in the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2000) 5.57
Cytoskeletal dynamics and nerve growth. Neuron (1988) 5.53
Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15. Nature (1984) 5.53
Systematic changes in gene expression patterns following adaptive evolution in yeast. Proc Natl Acad Sci U S A (1999) 5.45