Published in J Biol Chem on January 18, 2001
The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors. Br J Pharmacol (2013) 5.74
LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes. Nat Med (2015) 1.74
12-Hydroxyheptadecatrienoic acid promotes epidermal wound healing by accelerating keratinocyte migration via the BLT2 receptor. J Exp Med (2014) 1.54
Identification of the orphan G protein-coupled receptor GPR31 as a receptor for 12-(S)-hydroxyeicosatetraenoic acid. J Biol Chem (2011) 1.23
12(S)-Hydroxyheptadeca-5Z, 8E, 10E-trienoic acid is a natural ligand for leukotriene B4 receptor 2. J Exp Med (2008) 1.21
An update on the role of leukotrienes in asthma. Curr Opin Allergy Clin Immunol (2010) 1.16
Role of the lipoxygenase pathway in RSV-induced alternatively activated macrophages leading to resolution of lung pathology. Mucosal Immunol (2013) 1.01
Bioactive lipoxygenase metabolites stimulation of NADPH oxidases and reactive oxygen species. Mol Cells (2011) 0.97
Role of leukotriene B4 receptors in rheumatoid arthritis. Autoimmun Rev (2007) 0.95
Leukotrienes modulate cytokine release from dendritic cells. Immunology (2005) 0.92
Differential induction of BLT receptor expression on human endothelial cells by lipopolysaccharide, cytokines, and leukotriene B4. Proc Natl Acad Sci U S A (2006) 0.92
5-Lipoxygenase Pathway, Dendritic Cells, and Adaptive Immunity. J Biomed Biotechnol (2004) 0.90
Leukotrienes in atherosclerosis: new target insights and future therapy perspectives. Mediators Inflamm (2010) 0.90
Leukotriene B4 enhances innate immune defense against the puerperal sepsis agent Streptococcus pyogenes. J Immunol (2013) 0.88
Increased bovine Tim-3 and its ligand expressions during bovine leukemia virus infection. Vet Res (2012) 0.86
Structural determinants for calcium mobilization by prostaglandin E2 and prostaglandin F2alpha glyceryl esters in RAW 264.7 cells and H1819 cells. Prostaglandins Other Lipid Mediat (2010) 0.84
A distinctive role of the leukotriene B4 receptor BLT1 in osteoclastic activity during bone loss. Proc Natl Acad Sci U S A (2009) 0.84
Leukotriene A4 hydrolase: selective abrogation of leukotriene B4 formation by mutation of aspartic acid 375. Proc Natl Acad Sci U S A (2002) 0.83
Endothelial 12(S)-HETE vasorelaxation is mediated by thromboxane receptor inhibition in mouse mesenteric arteries. Am J Physiol Heart Circ Physiol (2012) 0.82
Involvement of the BLT2 receptor in the itch-associated scratching induced by 12-(S)-lipoxygenase products in ICR mice. Br J Pharmacol (2008) 0.81
Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s. J Exp Med (2016) 0.79
Cooperative and redundant signaling of leukotriene B4 and leukotriene D4 in human monocytes. Allergy (2011) 0.79
Anti-inflammatory action of ethanolic extract of Ramulus mori on the BLT2-linked cascade. BMB Rep (2016) 0.78
BLT2 expression improves skin integrity and protects from alterations caused by hyperglycemia in type 2 diabetes. Dermatoendocrinol (2016) 0.75
Human articular chondrocytes express functional leukotriene B4 receptors. J Anat (2015) 0.75
Macrophage LTB4 drives efficient phagocytosis of Borrelia burgdorferi via BLT1 or BLT2. J Lipid Res (2017) 0.75
The 5-Lipoxygenase as modulator of Alzheimer's γ-secretase and therapeutic target. Brain Res Bull (2016) 0.75
A broad-spectrum lipidomics screen of antiinflammatory drug combinations in human blood. JCI Insight (2016) 0.75
Molecular mechanisms of target recognition by lipid GPCRs: relevance for cancer. Oncogene (2015) 0.75
Colon cancer cell-derived 12(S)-HETE induces the retraction of cancer-associated fibroblast via MLC2, RHO/ROCK and Ca(2+) signalling. Cell Mol Life Sci (2016) 0.75
Next-generation sequencing of the human TRPV1 gene and the regulating co-players LTB4R and LTB4R2 based on a custom AmpliSeq™ panel. PLoS One (2017) 0.75
Cytokine and Lipid Mediator Regulation of Group 2 Innate Lymphoid Cells (ILC2s) in Human Allergic Airway Disease. J Cytokine Biol (2017) 0.75
A 300 kilobase interval genetic map of rice including 883 expressed sequences. Nat Genet (1994) 5.08
Clinical Studies on Behçet's Syndrome. Ann Rheum Dis (1963) 4.61
Interleukin 2 high-affinity receptor expression requires two distinct binding proteins. J Exp Med (1987) 4.53
DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]. Nature (2000) 4.40
A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis. Nature (1997) 4.27
Behçet disease (Behçet syndrome). Semin Arthritis Rheum (1979) 3.88
A mutation in the insulin 2 gene induces diabetes with severe pancreatic beta-cell dysfunction in the Mody mouse. J Clin Invest (1999) 3.86
A model for replication repair in mammalian cells. J Mol Biol (1976) 3.78
Endogenous tumor necrosis factor (cachectin) is essential to host resistance against Listeria monocytogenes infection. Infect Immun (1988) 3.70
Studies on protein binding of cefazolin and other antibiotics. Jpn J Antibiot (1974) 3.59
Chromospheric alfvenic waves strong enough to power the solar wind. Science (2007) 3.58
Glycogen-Storage Disease: Thesaurismosis Glycogenica (von Gierke). Am J Pathol (1934) 3.49
IFNβ-1b may severely exacerbate Japanese optic-spinal MS in neuromyelitis optica spectrum. Neurology (2010) 3.34
Revision of consensus sequence of human Alu repeats--a review. Gene (1987) 3.22
MHC class II molecules are not required for survival of newly generated CD4+ T cells, but affect their long-term life span. Immunity (1996) 3.20
Neurological response to early removal of ovarian teratoma in anti-NMDAR encephalitis. J Neurol Neurosurg Psychiatry (2007) 3.12
Serum IgG antibody to ganglioside GQ1b is a possible marker of Miller Fisher syndrome. Ann Neurol (1992) 3.04
Molecular cloning of the human cholecystokinin gene by use of a synthetic probe containing deoxyinosine. Proc Natl Acad Sci U S A (1985) 3.01
Quantitative analysis of Epstein-Barr virus load by using a real-time PCR assay. J Clin Microbiol (1999) 2.95
Role of cytosolic phospholipase A2 in allergic response and parturition. Nature (1997) 2.88
Calcium stores regulate the polarity and input specificity of synaptic modification. Nature (2000) 2.84
Indoleamine 2,3-dioxygenase. Purification and some properties. J Biol Chem (1978) 2.78
Focused Assessment with Sonography for Trauma (FAST): results from an international consensus conference. J Trauma (1999) 2.71
Improvement of survival in patients with diffuse panbronchiolitis treated with low-dose erythromycin. Am J Respir Crit Care Med (1998) 2.69
Acute lung injury by sepsis and acid aspiration: a key role for cytosolic phospholipase A2. Nat Immunol (2000) 2.67
Role of cell-surface lysines in plasminogen binding to cells: identification of alpha-enolase as a candidate plasminogen receptor. Biochemistry (1991) 2.66
Allelic variation at the VRN-1 promoter region in polyploid wheat. Theor Appl Genet (2004) 2.61
Stimulation of human 8-oxoguanine-DNA glycosylase by AP-endonuclease: potential coordination of the initial steps in base excision repair. Nucleic Acids Res (2001) 2.52
Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain. EMBO J (2000) 2.49
Clinicopathological study of fatal myocardial sarcoidosis. Ann N Y Acad Sci (1976) 2.47
Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sites. Genes Dev (1998) 2.46
Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals. Proc Natl Acad Sci U S A (1998) 2.42
Combination therapy with fluconazole and flucytosine for cryptococcal meningitis in Ugandan patients with AIDS. Clin Infect Dis (1998) 2.40
The effects of propofol, isoflurane, and sevoflurane on oxygenation and shunt fraction during one-lung ventilation. Anesth Analg (1998) 2.38
Structures of sialylated O-linked oligosaccharides of bovine peripheral nerve alpha-dystroglycan. The role of a novel O-mannosyl-type oligosaccharide in the binding of alpha-dystroglycan with laminin. J Biol Chem (1997) 2.38
Biosynthesis of lysosomal hydrolases: their synthesis in bound polysomes and the role of co- and post-translational processing in determining their subcellular distribution. J Cell Biol (1982) 2.37
Daily walking combined with diet therapy is a useful means for obese NIDDM patients not only to reduce body weight but also to improve insulin sensitivity. Diabetes Care (1995) 2.33
A second leukotriene B(4) receptor, BLT2. A new therapeutic target in inflammation and immunological disorders. J Exp Med (2000) 2.30
Position of immobilization after dislocation of the glenohumeral joint. A study with use of magnetic resonance imaging. J Bone Joint Surg Am (2001) 2.24
Idiopathic nonspecific interstitial pneumonia/fibrosis: comparison with idiopathic pulmonary fibrosis and BOOP. Eur Respir J (1998) 2.23
Frequent beta-catenin mutation and cytoplasmic/nuclear accumulation in pancreatic solid-pseudopapillary neoplasm. Cancer Res (2001) 2.22
Impact of single-port cholecystectomy on postoperative pain. Br J Surg (2011) 2.14
Giant negative thermal expansion in magnetic nanocrystals. Nat Nanotechnol (2008) 2.14
New and reliable MRI diagnosis for progressive supranuclear palsy. Neurology (2005) 2.14
Properties of gastric smooth muscles obtained from mice which lack inositol trisphosphate receptor. J Physiol (2000) 2.11
Induction of metaphase arrest in cleaving Xenopus embryos by MAP kinase. Science (1993) 2.08
Receptor-mediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD). J Physiol (2001) 2.08
Changes in gastric acid secretion assayed by endoscopic gastrin test before and after Helicobacter pylori eradication. Gut (2000) 2.06
Purification and characterization of human NTH1, a homolog of Escherichia coli endonuclease III. Direct identification of Lys-212 as the active nucleophilic residue. J Biol Chem (1998) 2.06
Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acid. Proc Natl Acad Sci U S A (1984) 2.05
Transfection of CD14 into 70Z/3 cells dramatically enhances the sensitivity to complexes of lipopolysaccharide (LPS) and LPS binding protein. J Exp Med (1992) 2.05
Peptide sequences for sucrose splitting and glucan binding within Streptococcus sobrinus glucosyltransferase (water-insoluble glucan synthetase). J Bacteriol (1991) 2.05
Prognostic determinants of long-term survival in Japanese patients with cardiac sarcoidosis treated with prednisone. Am J Cardiol (2001) 2.03
Platelet-activating factor (PAF) receptor and genetically engineered PAF receptor mutant mice. Prog Lipid Res (2000) 2.03
Intraoral minor salivary gland tumors: a clinicopathological study of 82 cases. Int J Oral Maxillofac Surg (2005) 2.02
Comparison of discriminative properties among disease-specific questionnaires for measuring health-related quality of life in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (1998) 2.01
Keratosis follicularis squamosa (Dohi): a follicular keratotic disorder well known in Japan. Br J Dermatol (2001) 2.01
Sensorimotor gating abnormalities in young males with fragile X syndrome and Fmr1-knockout mice. Mol Psychiatry (2004) 2.00
Decline in sex ratio at birth after Kobe earthquake. Hum Reprod (1998) 1.98
Impaired anaphylactic responses with intact sensitivity to endotoxin in mice lacking a platelet-activating factor receptor. J Exp Med (1998) 1.98
Early gastric cancer. Endoscopic diagnosis of depth of invasion. Dig Dis Sci (1990) 1.94
Diffuse panbronchiolitis. A disease of the transitional zone of the lung. Chest (1983) 1.93
Mutations in SIP1, encoding Smad interacting protein-1, cause a form of Hirschsprung disease. Nat Genet (2001) 1.93
Adherence of Bordetella bronchiseptica to swine nasal epithelial cells and its possible role in virulence. Res Vet Sci (1979) 1.93
A novel phosphodiesterase from cultured tobacco cells. Biochemistry (1976) 1.90
Pulmonary lymphangioleiomyomatosis: a report of 46 patients including a clinicopathologic study of prognostic factors. Am J Respir Crit Care Med (1995) 1.89
Immunohistochemical localization of gamma-enolase in normal human tissues other than nervous and neuroendocrine tissues. Lab Invest (1985) 1.89
Airway wall thickness in asthma assessed by computed tomography. Relation to clinical indices. Am J Respir Crit Care Med (2000) 1.88
A novel experimental model of giant cell myocarditis induced in rats by immunization with cardiac myosin fraction. Clin Immunol Immunopathol (1990) 1.88
Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue. J Biol Chem (1998) 1.86
Nuclear magnetic resonance study of antibodies: a multinuclear approach. Methods Enzymol (1994) 1.85
Protective role of ATP-sensitive potassium channels in hypoxia-induced generalized seizure. Science (2001) 1.84
Immunological studies on Behçet's syndrome. Ann Rheum Dis (1965) 1.82
The virR/virS locus regulates the transcription of genes encoding extracellular toxin production in Clostridium perfringens. J Bacteriol (1996) 1.82
Partial purification and characterization of UDPG:t-cinnamate glucosyltransferase in the root of sweet potato, Ipomoea batatas Lam. J Biochem (1984) 1.82
Chronic central infusion of ghrelin increases hypothalamic neuropeptide Y and Agouti-related protein mRNA levels and body weight in rats. Diabetes (2001) 1.82
Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease. Hum Mol Genet (2001) 1.81
Generation and characterization of a human immunodeficiency virus type 1 (HIV-1) mutant resistant to an HIV-1 protease inhibitor. J Virol (1994) 1.80
Gliding mutants of Mycoplasma mobile: relationships between motility and cell morphology, cell adhesion and microcolony formation. Microbiology (2000) 1.80
Successful and safe use of 2 min cold atmospheric argon plasma in chronic wounds: results of a randomized controlled trial. Br J Dermatol (2012) 1.78
Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences. EMBO J (1999) 1.77
Intensive expansion of natural killer T cells in the early phase of hepatocyte regeneration after partial hepatectomy in mice and its association with sympathetic nerve activation. Hepatology (2000) 1.76
Arachidonic acid metabolites as intracellular modulators of the G protein-gated cardiac K+ channel. Nature (1989) 1.74
Genetic analyses of GII.17 norovirus strains in diarrheal disease outbreaks from December 2014 to March 2015 in Japan reveal a novel polymerase sequence and amino acid substitutions in the capsid region. Euro Surveill (2015) 1.73
Pulmonary epithelioid haemangioendothelioma in 21 patients, including three with partial spontaneous regression. Eur Respir J (1998) 1.73
A simple assessment of dyspnoea as a prognostic indicator in idiopathic pulmonary fibrosis. Eur Respir J (2010) 1.72
Sequence determination and functional analysis of the Akabane virus (family Bunyaviridae) L RNA segment. Arch Virol (2007) 1.72
Helicobacter pylori infection prevents erosive reflux oesophagitis by decreasing gastric acid secretion. Gut (2001) 1.71
Human serum beta-glucuronidase; its measurement and some of its properties. Clin Chim Acta (1967) 1.71
Atrophic rhinitis produced by intranasal inoculation of Bordetella bronchiseptica in hysterectomy produced colostrum-deprived pigs. Cornell Vet (1971) 1.71
Cytotoxic effects of cigarette smoke extract on an alveolar type II cell-derived cell line. Am J Physiol Lung Cell Mol Physiol (2001) 1.71
Expression of coxsackievirus and adenovirus receptor in hearts of rats with experimental autoimmune myocarditis. Circ Res (2000) 1.70
Notable diversity in peptide composition of murine H-2K and H-2D alloantigens. Biochemistry (1974) 1.70
Impaired learning with enhanced hippocampal long-term potentiation in PTPdelta-deficient mice. EMBO J (2000) 1.70
Leukotriene A4 hydrolase in human leukocytes. Purification and properties. J Biol Chem (1984) 1.70
Quantitative analysis of 'plaque material' in the inner- and outer wall of Schlemm's canal in normal- and glaucomatous eyes. Exp Eye Res (1986) 1.70