Published in Neuron on March 01, 2001
Caged compounds: photorelease technology for control of cellular chemistry and physiology. Nat Methods (2007) 3.22
Transfer characteristics of the hair cell's afferent synapse. Proc Natl Acad Sci U S A (2006) 2.33
Tuning of synapse number, structure and function in the cochlea. Nat Neurosci (2009) 2.29
A highly Ca2+-sensitive pool of vesicles contributes to linearity at the rod photoreceptor ribbon synapse. Neuron (2004) 2.14
Time course and calcium dependence of transmitter release at a single ribbon synapse. Proc Natl Acad Sci U S A (2007) 2.11
Ca(2+) and calmodulin initiate all forms of endocytosis during depolarization at a nerve terminal. Nat Neurosci (2009) 2.07
Synaptic transmission at retinal ribbon synapses. Prog Retin Eye Res (2005) 1.85
Synaptic ribbon enables temporal precision of hair cell afferent synapse by increasing the number of readily releasable vesicles: a modeling study. J Neurophysiol (2008) 1.83
Ca2+ microdomains near plasma membrane Ca2+ channels: impact on cell function. J Physiol (2008) 1.83
The diverse roles of ribbon synapses in sensory neurotransmission. Nat Rev Neurosci (2010) 1.83
Increase in efficiency and reduction in Ca2+ dependence of exocytosis during development of mouse inner hair cells. J Physiol (2004) 1.82
Structure and function of the hair cell ribbon synapse. J Membr Biol (2006) 1.73
Control of exocytosis by synaptotagmins and otoferlin in auditory hair cells. J Neurosci (2010) 1.72
Local routes revisited: the space and time dependence of the Ca2+ signal for phasic transmitter release at the rat calyx of Held. J Physiol (2003) 1.68
Endocytosis at the synaptic terminal. J Physiol (2003) 1.67
Synaptotagmin isoforms couple distinct ranges of Ca2+, Ba2+, and Sr2+ concentration to SNARE-mediated membrane fusion. Mol Biol Cell (2005) 1.67
Calcium influx selects the fast mode of endocytosis in the synaptic terminal of retinal bipolar cells. Proc Natl Acad Sci U S A (2001) 1.58
Time and intensity coding at the hair cell's ribbon synapse. J Physiol (2005) 1.57
Onset coding is degraded in auditory nerve fibers from mutant mice lacking synaptic ribbons. J Neurosci (2010) 1.57
Formation, stabilisation and fusion of the readily releasable pool of secretory vesicles. Pflugers Arch (2004) 1.55
The molecular physiology of activity-dependent bulk endocytosis of synaptic vesicles. J Neurochem (2009) 1.49
Hearing requires otoferlin-dependent efficient replenishment of synaptic vesicles in hair cells. Nat Neurosci (2010) 1.48
Mechanisms underlying the temporal precision of sound coding at the inner hair cell ribbon synapse. J Physiol (2006) 1.46
Examining synaptotagmin 1 function in dense core vesicle exocytosis under direct control of Ca2+. J Gen Physiol (2003) 1.43
Frequency selectivity of synaptic exocytosis in frog saccular hair cells. Proc Natl Acad Sci U S A (2006) 1.37
Otoferlin is critical for a highly sensitive and linear calcium-dependent exocytosis at vestibular hair cell ribbon synapses. J Neurosci (2009) 1.37
The role of calcium/calmodulin-activated calcineurin in rapid and slow endocytosis at central synapses. J Neurosci (2010) 1.35
Nanodomain control of exocytosis is responsible for the signaling capability of a retinal ribbon synapse. J Neurosci (2010) 1.34
Exocytosis and endocytosis: modes, functions, and coupling mechanisms. Annu Rev Physiol (2013) 1.33
Calcium-dependent synaptic vesicle trafficking underlies indefatigable release at the hair cell afferent fiber synapse. Neuron (2011) 1.33
Sharp Ca²⁺ nanodomains beneath the ribbon promote highly synchronous multivesicular release at hair cell synapses. J Neurosci (2011) 1.33
A highly Ca2+-sensitive pool of granules is regulated by glucose and protein kinases in insulin-secreting INS-1 cells. J Gen Physiol (2004) 1.30
Null mutation of alpha1D Ca2+ channel gene results in deafness but no vestibular defect in mice. J Assoc Res Otolaryngol (2004) 1.29
Evidence that fast exocytosis can be predominantly mediated by vesicles not docked at active zones in frog saccular hair cells. J Physiol (2004) 1.29
A unifying basis of auditory thresholds based on temporal summation. Proc Natl Acad Sci U S A (2003) 1.28
Mechanisms of tonic, graded release: lessons from the vertebrate photoreceptor. J Physiol (2007) 1.27
Phase-locking precision is enhanced by multiquantal release at an auditory hair cell ribbon synapse. Neuron (2014) 1.26
Hair cell ribbon synapses. Cell Tissue Res (2006) 1.25
The molecular architecture of ribbon presynaptic terminals. Mol Neurobiol (2009) 1.24
Developmental shift to a mechanism of synaptic vesicle endocytosis requiring nanodomain Ca2+. Nat Neurosci (2010) 1.24
Hair cell afferent synapses. Curr Opin Neurobiol (2008) 1.22
Ribeye is required for presynaptic Ca(V)1.3a channel localization and afferent innervation of sensory hair cells. Development (2011) 1.17
Recovery from short-term depression and facilitation is ultrafast and Ca2+ dependent at auditory hair cell synapses. J Neurosci (2011) 1.17
Chick cochlear hair cell exocytosis mediated by dihydropyridine-sensitive calcium channels. J Physiol (2001) 1.17
Direct interaction of otoferlin with syntaxin 1A, SNAP-25, and the L-type voltage-gated calcium channel Cav1.3. J Biol Chem (2008) 1.15
The Ca2+ channel subunit beta2 regulates Ca2+ channel abundance and function in inner hair cells and is required for hearing. J Neurosci (2009) 1.14
SNARE proteins synaptobrevin, SNAP-25, and syntaxin are involved in rapid and slow endocytosis at synapses. Cell Rep (2013) 1.13
Probing the functional equivalence of otoferlin and synaptotagmin 1 in exocytosis. J Neurosci (2011) 1.11
Kinetics of synaptic transmission at ribbon synapses of rods and cones. Mol Neurobiol (2007) 1.10
Fast endocytosis is inhibited by GABA-mediated chloride influx at a presynaptic terminal. Neuron (2004) 1.07
Developmental refinement of hair cell synapses tightens the coupling of Ca2+ influx to exocytosis. EMBO J (2014) 1.03
Location of release sites and calcium-activated chloride channels relative to calcium channels at the photoreceptor ribbon synapse. J Neurophysiol (2010) 1.02
Noise-induced hearing loss alters the temporal dynamics of auditory-nerve responses. Hear Res (2010) 1.02
Transmitter release from cochlear hair cells is phase locked to cyclic stimuli of different intensities and frequencies. J Neurosci (2012) 1.00
EHD4 and CDH23 are interacting partners in cochlear hair cells. J Biol Chem (2009) 1.00
Single Ca2+ channels and exocytosis at sensory synapses. J Physiol (2013) 0.99
Fast Ca2+ signals at mouse inner hair cell synapse: a role for Ca2+-induced Ca2+ release. J Physiol (2002) 0.98
Properties of exocytotic response in vertebrate photoreceptors. J Neurophysiol (2003) 0.95
The dynamic architecture of photoreceptor ribbon synapses: cytoskeletal, extracellular matrix, and intramembrane proteins. Vis Neurosci (2011) 0.93
Voltage-dependent calcium channels at the plasma membrane, but not vesicular channels, couple exocytosis to endocytosis. Cell Rep (2012) 0.92
Clathrin-mediated endocytosis at the synaptic terminal: bridging the gap between physiology and molecules. Traffic (2010) 0.92
Calcium cooperativity of exocytosis as a measure of Ca²+ channel domain overlap. Brain Res (2011) 0.91
Extrasynaptic vesicle recycling in mature hippocampal neurons. Nat Commun (2011) 0.90
Otoferlin couples to clathrin-mediated endocytosis in mature cochlear inner hair cells. J Neurosci (2013) 0.89
Release from the cone ribbon synapse under bright light conditions can be controlled by the opening of only a few Ca(2+) channels. J Neurophysiol (2011) 0.89
Developmental changes in Ca2+ channel subtypes regulating endocytosis at the calyx of Held. J Physiol (2014) 0.89
Quantitative analysis of synaptic release at the photoreceptor synapse. Biophys J (2010) 0.88
Does the brain connect before the periphery can direct? A comparison of three sensory systems in mice. Brain Res (2009) 0.87
The yin and yang of calcium effects on synaptic vesicle endocytosis. J Neurosci (2014) 0.86
Ca2+ current versus Ca2+ channel cooperativity of exocytosis. J Neurosci (2009) 0.85
Synaptic release at mammalian bipolar cell terminals. Vis Neurosci (2011) 0.85
Rapid synaptic vesicle endocytosis in cone photoreceptors of salamander retina. J Neurosci (2012) 0.85
TRPC-like conductance mediates restoration of intracellular Ca2+ in cochlear outer hair cells in the guinea pig and rat. J Physiol (2006) 0.85
The dynamics of somatic exocytosis in monoaminergic neurons. Front Physiol (2012) 0.84
2,1,3-Benzothiadiazole (BTD)-moiety-containing red emitter conjugated amphiphilic poly(ethylene glycol)-block-poly(epsilon-caprolactone) copolymers for bioimaging. J Mater Chem (2010) 0.84
Functional properties of synaptic transmission in primary sense organs. J Neurosci (2009) 0.84
Effects of cinnarizine on calcium and pressure-dependent potassium currents in guinea pig vestibular hair cells. Naunyn Schmiedebergs Arch Pharmacol (2005) 0.84
Towards a unifying basis of auditory thresholds: the effects of hearing loss on temporal integration reconsidered. J Assoc Res Otolaryngol (2004) 0.84
Modes and regulation of endocytic membrane retrieval in mouse auditory hair cells. J Neurosci (2014) 0.83
The structural and functional differentiation of hair cells in a lizard's basilar papilla suggests an operational principle of amniote cochleas. J Neurosci (2007) 0.83
Summing Across Different Active Zones can Explain the Quasi-Linear Ca-Dependencies of Exocytosis by Receptor Cells. Front Synaptic Neurosci (2010) 0.83
Potassium currents induced by hydrostatic pressure modulate membrane potential and transmitter release in vestibular type II hair cells. Pflugers Arch (2008) 0.82
Calcium signaling in the cochlea - Molecular mechanisms and physiopathological implications. Cell Commun Signal (2012) 0.82
EF hand-mediated Ca- and cGMP-signaling in photoreceptor synaptic terminals. Front Mol Neurosci (2012) 0.82
Calcium regulates molecular interactions of otoferlin with soluble NSF attachment protein receptor (SNARE) proteins required for hair cell exocytosis. J Biol Chem (2014) 0.81
A unified mechanism for spontaneous-rate and first-spike timing in the auditory nerve. J Comput Neurosci (2002) 0.81
Using fluorine-containing amphiphilic random copolymers to manipulate the quantum yields of aggregation-induced emission fluorophores in aqueous solutions and the use of these polymers for fluorescent bioimaging. J Mater Chem (2012) 0.80
Clathrin-mediated endocytosis in snake motor terminals is directly facilitated by intracellular Ca2+. J Physiol (2005) 0.80
Hair cell synaptic dysfunction, auditory fatigue and thermal sensitivity in otoferlin Ile515Thr mutants. EMBO J (2016) 0.79
New insights into cochlear sound encoding. F1000Res (2016) 0.79
Synaptic studies inform the functional diversity of cochlear afferents. Hear Res (2015) 0.79
Pharmacological modulation of transmitter release by inhibition of pressure-dependent potassium currents in vestibular hair cells. Naunyn Schmiedebergs Arch Pharmacol (2009) 0.79
Elementary properties of Ca(2+) channels and their influence on multivesicular release and phase-locking at auditory hair cell ribbon synapses. Front Cell Neurosci (2015) 0.78
Ribbon synapses in zebrafish hair cells. Hear Res (2015) 0.78
Calcium-Induced calcium release during action potential firing in developing inner hair cells. Biophys J (2015) 0.77
PKC-induced sensitization of Ca2+-dependent exocytosis is mediated by reducing the Ca2+ cooperativity in pituitary gonadotropes. J Gen Physiol (2005) 0.77
A series of poly[N-(2-hydroxypropyl)methacrylamide] copolymers with anthracene-derived fluorophores showing aggregation-induced emission properties for bioimaging. J Polym Sci A Polym Chem (2012) 0.77
Rapid kinetics of endocytosis at rod photoreceptor synapses depends upon endocytic load and calcium. Vis Neurosci (2014) 0.77
Membrane properties specialize mammalian inner hair cells for frequency or intensity encoding. Elife (2015) 0.77
Modeling auditory coding: from sound to spikes. Cell Tissue Res (2015) 0.77
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch (1981) 134.60
Single-channel currents recorded from membrane of denervated frog muscle fibres. Nature (1976) 13.78
Sodium and calcium channels in bovine chromaffin cells. J Physiol (1982) 12.64
A patch-clamp study of bovine chromaffin cells and of their sensitivity to acetylcholine. J Physiol (1982) 10.42
Local anaesthetics transiently block currents through single acetylcholine-receptor channels. J Physiol (1978) 10.05
Discrete changes of cell membrane capacitance observed under conditions of enhanced secretion in bovine adrenal chromaffin cells. Proc Natl Acad Sci U S A (1982) 8.20
Correction for liquid junction potentials in patch clamp experiments. Methods Enzymol (1992) 8.06
Conductance fluctuations and ionic pores in membranes. Annu Rev Biophys Bioeng (1977) 7.60
Rates of diffusional exchange between small cells and a measuring patch pipette. Pflugers Arch (1988) 7.30
Single acetylcholine-activated channels show burst-kinetics in presence of desensitizing concentrations of agonist. Nature (1980) 6.83
Inward current channels activated by intracellular Ca in cultured cardiac cells. Nature (1981) 6.62
Voltage dependence of K channels in guard-cell protoplasts. Proc Natl Acad Sci U S A (1987) 6.40
Capacitance measurements reveal stepwise fusion events in degranulating mast cells. Nature (1985) 5.41
Delay in vesicle fusion revealed by electrochemical monitoring of single secretory events in adrenal chromaffin cells. Nature (1992) 5.23
Two fast transient current components during voltage clamp on snail neurons. J Gen Physiol (1971) 5.15
Patch-clamp techniques for time-resolved capacitance measurements in single cells. Pflugers Arch (1988) 4.88
Single Na+ channel currents observed in cultured rat muscle cells. Nature (1980) 4.82
Calcium dependence of the rate of exocytosis in a synaptic terminal. Nature (1994) 4.77
Mobile and immobile calcium buffers in bovine adrenal chromaffin cells. J Physiol (1993) 4.61
Single channel recordings of K+ currents in squid axons. Nature (1980) 4.48
Intracellular calcium dependence of transmitter release rates at a fast central synapse. Nature (2000) 4.46
The extracellular patch clamp: a method for resolving currents through individual open channels in biological membranes. Pflugers Arch (1978) 4.42
The Ca signal from fura-2 loaded mast cells depends strongly on the method of dye-loading. FEBS Lett (1985) 3.95
The charge carried by single-channel currents of rat cultured muscle cells in the presence of local anaesthetics. J Physiol (1983) 3.76
Potassium channels in cultured bovine adrenal chromaffin cells. J Physiol (1985) 3.60
Regulation of calcium influx by second messengers in rat mast cells. Nature (1988) 3.60
Multiple kinetic components of exocytosis distinguished by neurotoxin sensitivity. Nat Neurosci (1998) 3.37
Calcium requirements for secretion in bovine chromaffin cells. J Physiol (1992) 3.34
Highly nonlinear photodamage in two-photon fluorescence microscopy. Biophys J (2001) 3.34
Linearized buffered Ca2+ diffusion in microdomains and its implications for calculation of [Ca2+] at the mouth of a calcium channel. J Neurosci (1997) 3.28
Voltage-dependence of drug-induced conductance in frog neuromuscular junction. Proc Natl Acad Sci U S A (1975) 3.18
Kinetics of the secretory response in bovine chromaffin cells following flash photolysis of caged Ca2+. Biophys J (1994) 3.14
Released fraction and total size of a pool of immediately available transmitter quanta at a calyx synapse. Neuron (1999) 3.04
Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4. Proc Natl Acad Sci U S A (2003) 2.95
Calmodulin mediates rapid recruitment of fast-releasing synaptic vesicles at a calyx-type synapse. Neuron (2001) 2.90
Patch clamp techniques for studying ionic channels in excitable membranes. Annu Rev Physiol (1984) 2.86
Munc18-1 promotes large dense-core vesicle docking. Neuron (2001) 2.71
Ionic selectivity, saturation, and block in gramicidin A channels. II. Saturation behavior of single channel conductances and evidence for the existence of multiple binding sites in the channel. J Membr Biol (1978) 2.71
Fractional contribution of calcium to the cation current through glutamate receptor channels. Neuron (1993) 2.69
Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release. Neuron (1998) 2.68
Fractional calcium currents through recombinant GluR channels of the NMDA, AMPA and kainate receptor subtypes. J Physiol (1995) 2.67
Noise analysis of drug induced voltage clamp currents in denervated frog muscle fibres. J Physiol (1976) 2.62
Protein kinase C enhances exocytosis from chromaffin cells by increasing the size of the readily releasable pool of secretory granules. Neuron (1996) 2.59
Inhibition of SNARE complex assembly differentially affects kinetic components of exocytosis. Cell (1999) 2.49
Ionic selectivity, saturation and block in gramicidin A channels: I. Theory for the electrical properties of ion selective channels having two pairs of binding sites and multiple conductance states. J Membr Biol (1977) 2.49
Modeling buffered Ca2+ diffusion near the membrane: implications for secretion in neuroendocrine cells. Biophys J (1997) 2.48
Rapid changes of potassium concentration at the outer surface of exposed single neurons during membrane current flow. J Gen Physiol (1973) 2.46
Rat brain serotonin receptors in Xenopus oocytes are coupled by intracellular calcium to endogenous channels. Proc Natl Acad Sci U S A (1987) 2.41
Properties of volume-regulated anion channels in mammalian cells. Prog Biophys Mol Biol (1997) 2.39
Modulation of the Ca2 permeable cation channel TRPV4 by cytochrome P450 epoxygenases in vascular endothelium. Circ Res (2005) 2.38
Homo- and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6. EMBO J (2003) 2.35
A Ca-dependent early step in the release of catecholamines from adrenal chromaffin cells. Science (1993) 2.29
Single channel activity associated with the calcium dependent outward current in Helix pomatia. Pflugers Arch (1981) 2.29
Substance P reduces acetylcholine-induced currents in isolated bovine chromaffin cells. J Physiol (1984) 2.09
The equilibration time course of (K + ) 0 in cat cortex. Exp Brain Res (1973) 2.04
Mechanisms underlying phasic and sustained secretion in chromaffin cells from mouse adrenal slices. Neuron (1999) 2.01
Kinetic studies of Ca2+ binding and Ca2+ clearance in the cytosol of adrenal chromaffin cells. Biophys J (1997) 1.99
The presynaptic function of mouse cochlear inner hair cells during development of hearing. J Neurosci (2001) 1.99
Munc13-1 acts as a priming factor for large dense-core vesicles in bovine chromaffin cells. EMBO J (2000) 1.98
Fast calcium transients in rat peritoneal mast cells are not sufficient to trigger exocytosis. EMBO J (1986) 1.94
Interactions in cation permeation through the gramicidin channel. Cs, Rb, K, Na, Li, Tl, H, and effects of anion binding. Biophys J (1978) 1.91
Ca(2+)-dependent exocytosis in the somata of dorsal root ganglion neurons. Neuron (1996) 1.91
Differential action of TEA + on two K + -current componentss of a molluscan neurone. Pflugers Arch (1972) 1.89
Fast scanning and efficient photodetection in a simple two-photon microscope. J Neurosci Methods (1999) 1.89
Multiple forms of endocytosis in bovine adrenal chromaffin cells. J Cell Biol (1997) 1.85
Presynaptic depression at a calyx synapse: the small contribution of metabotropic glutamate receptors. J Neurosci (1997) 1.84
Volume-activated Cl- channels. Gen Pharmacol (1996) 1.80
Cytosolic Ca2+ acts by two separate pathways to modulate the supply of release-competent vesicles in chromaffin cells. Neuron (1998) 1.79
Structure and function of the hair cell ribbon synapse. J Membr Biol (2006) 1.73
Quantitative relationship between transmitter release and calcium current at the calyx of held synapse. J Neurosci (2001) 1.69
The role of calcium in stimulus-secretion coupling in excitable and non-excitable cells. J Exp Biol (1988) 1.67
IgG from patients with Lambert-Eaton syndrome blocks voltage-dependent calcium channels. Science (1988) 1.66
Calcium permeability of nicotinic acetylcholine receptor channels in bovine adrenal chromaffin cells. Pflugers Arch (1993) 1.65
A two-step model of secretion control in neuroendocrine cells. Pflugers Arch (1993) 1.64
Mechanisms determining the time course of secretion in neuroendocrine cells. Neuron (1996) 1.62
Optimizing imaging parameters for the separation of multiple labels in a fluorescence image. J Microsc (2004) 1.62
Second messenger-activated calcium influx in rat peritoneal mast cells. J Physiol (1989) 1.62
Volume-sensitive chloride conductance in bovine chromaffin cell membrane. J Physiol (1992) 1.57
Low mobility of the Ca2+ buffers in axons of cultured Aplysia neurons. Neuron (1997) 1.57
The influence of phospholipid polar groups on gramicidin channels. Biochim Biophys Acta (1977) 1.56
Properties of somatic membrane patches of snail neurons under voltage clamp. Pflugers Arch (1971) 1.56
Calcium-activated chloride channels in bovine pulmonary artery endothelial cells. J Physiol (1997) 1.55
Rapid exocytosis in single chromaffin cells recorded from mouse adrenal slices. J Neurosci (1997) 1.54
The equivalence of fluctuation analysis and chemical relaxation measurements: a kinetic study of ion pore formation in thin lipid membranes. Biophys Chem (1974) 1.53
Ultrastructural organization of bovine chromaffin cell cortex-analysis by cryofixation and morphometry of aspects pertinent to exocytosis. J Cell Biol (1997) 1.52
Differences in Ca2+ buffering properties between excitatory and inhibitory hippocampal neurons from the rat. J Physiol (2000) 1.51
Voltage clamp on Helix pomatia neuronal membrane; current measurement over a limited area of the soma surface. Pflugers Arch (1969) 1.51
Time course of Ca2+ concentration triggering exocytosis in neuroendocrine cells. Proc Natl Acad Sci U S A (1994) 1.49
Kinetics of Ca2+ binding to parvalbumin in bovine chromaffin cells: implications for [Ca2+] transients of neuronal dendrites. J Physiol (2000) 1.48
TRP channels in lower urinary tract dysfunction. Br J Pharmacol (2014) 1.48
Differential expression of volume-regulated anion channels during cell cycle progression of human cervical cancer cells. J Physiol (2000) 1.46
Chloride conductance activated by external agonists and internal messengers in rat peritoneal mast cells. J Physiol (1989) 1.46
Intracellular calcium dependence of large dense-core vesicle exocytosis in the absence of synaptotagmin I. Proc Natl Acad Sci U S A (2001) 1.45
Estimation of quantal size and number of functional active zones at the calyx of Held synapse by nonstationary EPSC variance analysis. J Neurosci (2001) 1.41