Published in J Immunol on May 15, 2001
Kynurenine is an endothelium-derived relaxing factor produced during inflammation. Nat Med (2010) 2.12
Structure-activity study of brassinin derivatives as indoleamine 2,3-dioxygenase inhibitors. J Med Chem (2006) 1.81
Indoleamine 2,3-dioxygenase: is it an immune suppressor? Cancer J (2010) 1.36
IDO and regulatory T cell support are critical for cytotoxic T lymphocyte-associated Ag-4 Ig-mediated long-term solid organ allograft survival. J Immunol (2011) 1.00
Differential regulation of indoleamine-2,3-dioxygenase (IDO) by HIV type 1 clade B and C Tat protein. AIDS Res Hum Retroviruses (2009) 0.99
Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease. Redox Rep (2010) 0.96
Fibroblasts from patients with Diamond-Blackfan anaemia show abnormal expression of genes involved in protein synthesis, amino acid metabolism and cancer. BMC Genomics (2009) 0.83
Monocyte-mediated T-cell suppression and augmented monocyte tryptophan catabolism after human hematopoietic stem-cell transplantation. Blood (2005) 0.81
Early Carcinogenesis Involves the Establishment of Immune Privilege via Intrinsic and Extrinsic Regulation of Indoleamine 2,3-dioxygenase-1: Translational Implications in Cancer Immunotherapy. Front Immunol (2014) 0.80
Statin effects on regulatory and proinflammatory factors in chronic idiopathic urticaria. Clin Exp Immunol (2011) 0.78
Decreased IDO activity and increased TTS expression break immune tolerance in patients with immune thrombocytopenia. J Clin Immunol (2011) 0.78
Human indoleamine 2,3-dioxygenase is a catalyst of physiological heme peroxidase reactions: implications for the inhibition of dioxygenase activity by hydrogen peroxide. J Biol Chem (2012) 0.77
The cystine/glutamate antiporter regulates indoleamine 2,3-dioxygenase protein levels and enzymatic activity in human dendritic cells. Am J Clin Exp Immunol (2012) 0.75
Redox Properties of Tryptophan Metabolism and the Concept of Tryptophan Use in Pregnancy. Int J Mol Sci (2017) 0.75
Bilirubin is an antioxidant of possible physiological importance. Science (1987) 11.26
Antioxidant defenses and lipid peroxidation in human blood plasma. Proc Natl Acad Sci U S A (1988) 3.42
Antioxidant activity of albumin-bound bilirubin. Proc Natl Acad Sci U S A (1987) 3.35
Biochemistry and pathology of radical-mediated protein oxidation. Biochem J (1997) 3.14
Inhibition of murine malaria (Plasmodium chabaudi) in vivo by recombinant interferon-gamma or tumor necrosis factor, and its enhancement by butylated hydroxyanisole. J Immunol (1987) 2.91
Sequence and analysis of the 60 kb conjugative, bacteriocin-producing plasmid pMRC01 from Lactococcus lactis DPC3147. Mol Microbiol (1998) 2.61
Evidence for reactive oxygen intermediates causing hemolysis and parasite death in malaria. Infect Immun (1983) 2.59
Free and albumin-bound bilirubin are efficient co-antioxidants for alpha-tocopherol, inhibiting plasma and low density lipoprotein lipid peroxidation. J Biol Chem (1994) 2.20
Relationship between procalcitonin plasma levels and severity of injury, sepsis, organ failure, and mortality in injured patients. Crit Care Med (2000) 2.19
High density lipoprotein is the major carrier of lipid hydroperoxides in human blood plasma from fasting donors. Proc Natl Acad Sci U S A (1992) 2.15
The health of smokers' and nonsmokers' children. J Allergy (1969) 2.07
Presence of hypochlorite-modified proteins in human atherosclerotic lesions. J Clin Invest (1996) 2.01
Character and duration of pharmacological effects of intravenous isoxsuprine. Equine Vet J (1996) 1.93
Function and regulation of transferrin and ferritin. Semin Hematol (1998) 1.84
Pathology of fatal and resolving Plasmodium berghei cerebral malaria in mice. Parasitology (1992) 1.78
Hypocretin-1 (orexin A) deficiency in acute traumatic brain injury. Neurology (2005) 1.76
Possible roles of tumor necrosis factor in the pathology of malaria. Am J Pathol (1987) 1.69
Rapid isolation of lipoproteins and assessment of their peroxidation by high-performance liquid chromatography postcolumn chemiluminescence. Methods Enzymol (1994) 1.68
Plasma total bilirubin levels predict amputation events in type 2 diabetes mellitus: the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. Diabetologia (2013) 1.61
Effect of antioxidants on primary alloantigen-induced T cell activation and proliferation. J Immunol (1986) 1.58
Oxidation of low-density lipoprotein with hypochlorite causes transformation of the lipoprotein into a high-uptake form for macrophages. Biochem J (1993) 1.55
Modafinil ameliorates excessive daytime sleepiness after traumatic brain injury. Neurology (2010) 1.55
The membrane-bound transferrin homologue melanotransferrin: roles other than iron transport? FEBS Lett (2000) 1.52
Oxidation of high density lipoproteins. II. Evidence for direct reduction of lipid hydroperoxides by methionine residues of apolipoproteins AI and AII. J Biol Chem (1998) 1.48
Breakdown of the blood-brain barrier in murine cerebral malaria. Parasitology (1988) 1.47
Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque. Biochem J (1998) 1.45
Oxidation of parenteral lipid emulsion by ambient and phototherapy lights: potential toxicity of routine parenteral feeding. J Pediatr (1995) 1.45
Vitamin E in human low-density lipoprotein. When and how this antioxidant becomes a pro-oxidant. Biochem J (1992) 1.43
Production of cytokines following brain injury: beneficial and deleterious for the damaged tissue. Mol Psychiatry (1997) 1.35
Human atherosclerotic plaque contains both oxidized lipids and relatively large amounts of alpha-tocopherol and ascorbate. Arterioscler Thromb Vasc Biol (1995) 1.34
Oxidation of low-density lipoprotein by hypochlorite causes aggregation that is mediated by modification of lysine residues rather than lipid oxidation. Biochem J (1994) 1.33
Early activation of microglia in the pathogenesis of fatal murine cerebral malaria. Glia (1997) 1.32
Incidence and clinical pattern of the abdominal compartment syndrome after "damage-control" laparotomy in 311 patients with severe abdominal and/or pelvic trauma. Crit Care Med (2000) 1.32
Immunologic detection and measurement of hypochlorite-modified LDL with specific monoclonal antibodies. Arterioscler Thromb Vasc Biol (1995) 1.32
Dramatic changes in oxidative tryptophan metabolism along the kynurenine pathway in experimental cerebral and noncerebral malaria. Am J Pathol (1998) 1.32
A field study of the effects of elevated CO(2) on plant biomass and community structure in a calcareous grassland. Oecologia (1999) 1.32
Nitric oxide inhibits indoleamine 2,3-dioxygenase activity in interferon-gamma primed mononuclear phagocytes. J Biol Chem (1994) 1.32
Dietary supplementation with coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation. Biochim Biophys Acta (1992) 1.31
Control of pathogenic CD8+ T cell migration to the brain by IFN-gamma during experimental cerebral malaria. Parasite Immunol (2008) 1.30
Antioxidants inhibit proliferation and cell surface expression of receptors for interleukin-2 and transferrin in T lymphocytes stimulated with phorbol myristate acetate and ionomycin. Cell Immunol (1988) 1.27
Resource patch formation and exploitation throughout the marine microbial food web. Am Nat (2009) 1.27
Free radical-induced pathology. Med Res Rev (1985) 1.26
Antioxidant activities of some tryptophan metabolites: possible implication for inflammatory diseases. Proc Natl Acad Sci U S A (1990) 1.25
Early microvascular changes in murine cerebral malaria detected in retinal wholemounts. Am J Pathol (1992) 1.19
A casein kinase I motif present in the cytoplasmic domain of members of the tumour necrosis factor ligand family is implicated in 'reverse signalling'. EMBO J (1999) 1.17
Correlation between enhanced vascular permeability, up-regulation of cellular adhesion molecules and monocyte adhesion to the endothelium in the retina during the development of fatal murine cerebral malaria. Am J Pathol (1996) 1.17
ATP-binding cassette transporter A1 mediates cellular secretion of alpha-tocopherol. J Biol Chem (2001) 1.16
Iron chelators for the treatment of cancer. Curr Med Chem (2012) 1.16
Tocopherol-mediated peroxidation of lipoproteins: implications for vitamin E as a potential antiatherogenic supplement. FASEB J (1999) 1.14
Identification of distinct changes in gene expression after modulation of melanoma tumor antigen p97 (melanotransferrin) in multiple models in vitro and in vivo. Carcinogenesis (2007) 1.14
Redistribution and degeneration of retinal astrocytes in experimental murine cerebral malaria: relationship to disruption of the blood-retinal barrier. Glia (1996) 1.14
Tumor necrosis factor-alpha expression in the brain during fatal murine cerebral malaria: evidence for production by microglia and astrocytes. Am J Pathol (1997) 1.14
Oxidative stress and the redox status of malaria-infected erythrocytes. Blood Cells (1990) 1.14
Requirement for, promotion, or inhibition by alpha-tocopherol of radical-induced initiation of plasma lipoprotein lipid peroxidation. Free Radic Biol Med (1997) 1.13
Radical-induced chain oxidation of proteins and its inhibition by chain-breaking antioxidants. Biochem J (1993) 1.13
Endoscopic subtotal thyroidectomy for patients with Graves' disease. Surg Today (2001) 1.13
Conventional and experimental treatment of cerebral malaria. Int J Parasitol (2006) 1.12
Central nervous system in cerebral malaria: 'Innocent bystander' or active participant in the induction of immunopathology? Immunol Cell Biol (2001) 1.12
Oxidative stress and abnormal cholesterol metabolism in patients with adult respiratory distress syndrome. J Lab Clin Med (1990) 1.12
Efflux of hepatic ascorbate: a potential contributor to the maintenance of plasma vitamin C. Biochem J (1999) 1.11
Antioxidant activities of bile pigments: biliverdin and bilirubin. Methods Enzymol (1990) 1.11
Oxidation of high density lipoproteins. I. Formation of methionine sulfoxide in apolipoproteins AI and AII is an early event that accompanies lipid peroxidation and can be enhanced by alpha-tocopherol. J Biol Chem (1998) 1.11
Effect of guanyl nucleotides on parathyroid hormone-responsive adenylate cyclase in chick kidney. J Endocrinol (1976) 1.10
Pressure relationships in the macro- and microcirculation of the mesentery. Microvasc Res (1970) 1.10
Redox reactions related to indoleamine 2,3-dioxygenase and tryptophan metabolism along the kynurenine pathway. Redox Rep (1999) 1.09
Deferasirox (ICL670A) effectively inhibits oesophageal cancer growth in vitro and in vivo. Br J Pharmacol (2013) 1.09
Myeloperoxidase binds to low-density lipoprotein: potential implications for atherosclerosis. FEBS Lett (2000) 1.09
Bilirubin attenuates radical-mediated damage to serum albumin. FEBS Lett (1993) 1.08
Molecular pharmacology of the interaction of anthracyclines with iron. Mol Pharmacol (2005) 1.08
Oxygen-derived free radicals in the pathogenesis of parasitic disease. Adv Parasitol (1986) 1.08
Autoxidation of lipids and antioxidation by alpha-tocopherol and ubiquinol in homogeneous solution and in aqueous dispersions of lipids: unrecognized consequences of lipid particle size as exemplified by oxidation of human low density lipoprotein. Proc Natl Acad Sci U S A (1993) 1.08
Hereditary sclerosing poikiloderma. Report of two families with an unusual and distinctive genodermatosis. Arch Dermatol (1969) 1.08
Ascorbate: the most effective antioxidant in human blood plasma. Adv Exp Med Biol (1990) 1.07
Increased fluorescence polarization of 1,6-diphenyl-1,3,5-hexatriene in the phorbol myristate acetate-stimulated plasma membrane of human neutrophils. FEBS Lett (1982) 1.07
Extubation after breathing trials with automatic tube compensation, T-tube, or pressure support ventilation. Acta Anaesthesiol Scand (2002) 1.06
Intrathecal and serum interleukin-6 and the acute-phase response in patients with severe traumatic brain injuries. Shock (1995) 1.06
Oxidation of methionine residues to methionine sulfoxides does not decrease potential antiatherogenic properties of apolipoprotein A-I. J Biol Chem (2000) 1.05
How accurate are our assumptions about our students' background knowledge? Am J Physiol (1999) 1.04
Different pattern of local and systemic release of proinflammatory and anti-inflammatory mediators in severely injured patients with chest trauma. J Trauma (1996) 1.04
Comparative antioxidant activity of tocotrienols and other natural lipid-soluble antioxidants in a homogeneous system, and in rat and human lipoproteins. Biochim Biophys Acta (1993) 1.04
Possible mechanisms responsible for the increased ascorbic acid content of Plasmodium vinckei-infected mouse erythrocytes. Biochim Biophys Acta (1986) 1.04
Oxidants and antioxidants in atherosclerosis. Curr Opin Lipidol (2001) 1.04
Parathyroid hormone-responsive adenylate cyclase in induced transplantable osteogenic rat sarcoma. Nature (1976) 1.03
Comparisons between microvascular changes in cerebral and non-cerebral malaria in mice, using the retinal whole-mount technique. Parasitology (1993) 1.03
Calcitonin-responsive adenylate cyclase in a calcitonin-producing human cancer cell line. Br J Cancer (1977) 1.02
Is ischemia involved in the pathogenesis of murine cerebral malaria? Am J Pathol (2001) 1.02
Examination of the mechanism(s) involved in doxorubicin-mediated iron accumulation in ferritin: studies using metabolic inhibitors, protein synthesis inhibitors, and lysosomotropic agents. Mol Pharmacol (2004) 1.01
Bp44mT: an orally active iron chelator of the thiosemicarbazone class with potent anti-tumour efficacy. Br J Pharmacol (2012) 1.00
Alterations in antioxidant defences in lung and liver of mice infected with influenza A virus. J Gen Virol (1992) 1.00
The participation of nitric oxide in cell free- and its restriction of macrophage-mediated oxidation of low-density lipoprotein. Biochim Biophys Acta (1992) 1.00
The oxidation of blood plasma and low density lipoprotein components by chemically generated singlet oxygen. J Biol Chem (1993) 1.00
ERK activation and mitogenesis in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol (2001) 1.00
Inhibition by interferon-gamma of human mononuclear cell-mediated low density lipoprotein oxidation. Participation of tryptophan metabolism along the kynurenine pathway. J Clin Invest (1994) 1.00
Inhibition of malignant cell growth by 311, a novel iron chelator of the pyridoxal isonicotinoyl hydrazone class: effect on the R2 subunit of ribonucleotide reductase. Clin Cancer Res (2001) 0.99
Antioxidants can prevent cerebral malaria in Plasmodium berghei-infected mice. Br J Exp Pathol (1989) 0.99
Interferon-gamma and lipopolysaccharide regulate the expression of Nramp2 and increase the uptake of iron from low relative molecular mass complexes by macrophages. Eur J Biochem (2000) 0.98