Published in Biochem Biophys Res Commun on July 20, 2001
Nitric oxide and peroxynitrite in health and disease. Physiol Rev (2007) 15.49
Protein nitration impairs the myogenic tone of rat middle cerebral arteries in both ischemic and nonischemic hemispheres after ischemic stroke. Am J Physiol Heart Circ Physiol (2013) 1.74
Peroxynitrite is a potent inhibitor of NF-{kappa}B activation triggered by inflammatory stimuli in cardiac and endothelial cell lines. J Biol Chem (2005) 1.13
Role of peroxynitrite in the redox regulation of cell signal transduction pathways. Front Biosci (Landmark Ed) (2009) 1.07
Peroxynitrite activates ERK via Raf-1 and MEK, independently from EGF receptor and p21Ras in H9C2 cardiomyocytes. J Mol Cell Cardiol (2005) 1.05
Effect of Cocoa and Its Flavonoids on Biomarkers of Inflammation: Studies of Cell Culture, Animals and Humans. Nutrients (2016) 0.99
Glutamine synthetase is a molecular target of nitric oxide in root nodules of Medicago truncatula and is regulated by tyrosine nitration. Plant Physiol (2011) 0.98
Cocoa polyphenols and their potential benefits for human health. Oxid Med Cell Longev (2012) 0.94
Oxidative modification and aggregation of creatine kinase from aged mouse skeletal muscle. Aging (Albany NY) (2009) 0.92
Inhibition of Arabidopsis O-acetylserine(thiol)lyase A1 by tyrosine nitration. J Biol Chem (2010) 0.90
The reactive nitrogen species peroxynitrite is a potent inhibitor of renal Na-K-ATPase activity. Am J Physiol Renal Physiol (2008) 0.82
Nox4 contributes to the hypoxia-mediated regulation of actin cytoskeleton in cerebrovascular smooth muscle. Life Sci (2016) 0.75
Flavan-3-ols consumption and cancer risk: A meta-analysis of epidemiologic studies. Oncotarget (2016) 0.75
Altered cytotoxicity of ROS-inducing compounds by sodium pyruvate in cell culture medium depends on the location of ROS generation. Springerplus (2015) 0.75
(-)-Epicatechin Prevents Blood Pressure Increase and Reduces Locomotor Hyperactivity in Young Spontaneously Hypertensive Rats. Oxid Med Cell Longev (2016) 0.75
Inhibitory Effects of Conjugated Epicatechin Metabolites on Peroxynitrite-mediated Nitrotyrosine Formation. J Clin Biochem Nutr (2008) 0.75
Antioxidant action of six Trifolium species in blood platelet experimental system in vitro. Mol Cell Biochem (2015) 0.75
Ishemia-reperfusion enhances GAPDH nitration in aging skeletal muscle. Aging (Albany NY) (2011) 0.75
Hydroperoxide metabolism in mammalian organs. Physiol Rev (1979) 14.13
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol (2001) 8.03
Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes. J Exp Med (2000) 5.90
Lycopene as the most efficient biological carotenoid singlet oxygen quencher. Arch Biochem Biophys (1989) 3.33
Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples. Methods Enzymol (1981) 2.85
Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-alpha. Biochem J (1989) 2.85
Toxic drug effects associated with oxygen metabolism: redox cycling and lipid peroxidation. Experientia (1981) 2.71
Spontaneous mutagenesis and oxidative damage to DNA in Salmonella typhimurium. Proc Natl Acad Sci U S A (1987) 2.51
Chemistry of biologically important synthetic organoselenium compounds. Chem Rev (2001) 2.41
A novel biologically active seleno-organic compound--I. Glutathione peroxidase-like activity in vitro and antioxidant capacity of PZ 51 (Ebselen). Biochem Pharmacol (1984) 1.90
Reversible conversion of nitroxyl anion to nitric oxide by superoxide dismutase. Proc Natl Acad Sci U S A (1991) 1.87
The use of perfusion of liver and other organs for the study of microsomal electron-transport and cytochrome P-450 systems. Methods Enzymol (1978) 1.86
The role of H 2 O 2 generation in perfused rat liver and the reaction of catalase compound I and hydrogen donors. Arch Biochem Biophys (1973) 1.81
Oxidative stress: damage to intact cells and organs. Philos Trans R Soc Lond B Biol Sci (1985) 1.55
Enzymology and physiology of reticulocyte lipoxygenase: comparison with other lipoxygenases. Adv Enzymol Relat Areas Mol Biol (1986) 1.54
Antioxidant defense systems: the role of carotenoids, tocopherols, and thiols. Am J Clin Nutr (1991) 1.54
Formation of 8-hydroxy(deoxy)guanosine and generation of strand breaks at guanine residues in DNA by singlet oxygen. Biochemistry (1991) 1.53
Low vitamin E content in plasma of patients with alcoholic liver disease, hemochromatosis and Wilson's disease. J Hepatol (1994) 1.52
Exocytosis in secretory cells of rat lacrimal gland. Peroxidase release from lobules and isolated cells upon cholinergic stimulation. J Cell Biol (1976) 1.50
Reduced and oxidized glutathione efflux from liver. FEBS Lett (1978) 1.49
Fluvastatin/fenofibrate vs. simvastatin/ezetimibe in patients with metabolic syndrome: different effects on LDL-profiles. Eur J Clin Invest (2009) 1.44
Glutathione peroxidase protects against peroxynitrite-mediated oxidations. A new function for selenoproteins as peroxynitrite reductase. J Biol Chem (1997) 1.44
Vitamin E in humans: demand and delivery. Annu Rev Nutr (1996) 1.42
The lipoxygenase of reticulocytes. Purification, characterization and biological dynamics of the lipoxygenase; its identity with the respiratory inhibitors of the reticulocyte. Eur J Biochem (1979) 1.40
Lycopene: a biologically important carotenoid for humans? Arch Biochem Biophys (1996) 1.38
Low-level chemiluminescence as an indicator of singlet molecular oxygen in biological systems. Methods Enzymol (1984) 1.37
Uptake of lycopene and its geometrical isomers is greater from heat-processed than from unprocessed tomato juice in humans. J Nutr (1992) 1.35
Role of cardiac glutathione transferase and of the glutathione S-conjugate export system in biotransformation of 4-hydroxynonenal in the heart. J Biol Chem (1986) 1.33
Lycopene is more bioavailable from tomato paste than from fresh tomatoes. Am J Clin Nutr (1997) 1.31
Singlet oxygen mediates the UVA-induced generation of the photoaging-associated mitochondrial common deletion. J Biol Chem (1999) 1.31
Identification and quantitation of glutathione in hepatic protein mixed disulfides and its relationship to glutathione disulfide. Biochem Pharmacol (1983) 1.31
Increased biliary glutathione disulfide release in chronically ethanol-treated rats. FEBS Lett (1979) 1.30
Hydroperoxide-metabolizing systems in rat liver. Eur J Biochem (1975) 1.29
The relationship of biliary glutathione disulfide efflux and intracellular glutathione disulfide content in perfused rat liver. J Biol Chem (1982) 1.27
Positional specificity of a reticulocyte lipoxygenase. Conversion of arachidonic acid to 15-S-hydroperoxy-eicosatetraenoic acid. J Biol Chem (1982) 1.25
S-nitrosylation and S-glutathiolation of protein sulfhydryls by S-nitroso glutathione. Arch Biochem Biophys (1999) 1.24
Mitochondrial and cytosolic NADPH systems and isocitrate dehydrogenase indicator metabolites during ureogensis from ammonia in isolated rat hepatocytes. Eur J Biochem (1977) 1.24
Singlet molecular oxygen causes loss of biological activity in plasmid and bacteriophage DNA and induces single-strand breaks. Biochim Biophys Acta (1989) 1.24
Functional hepatocyte heterogeneity in ammonia metabolism. The intercellular glutamine cycle. J Hepatol (1985) 1.22
Heme occupancy of catalase in hemoglobin-free perfused rat liver and of isolated rat liver catalase. Arch Biochem Biophys (1973) 1.22
Activation of pyruvate dehydrogenase during metabolism of ammonium ions in hemoglobin-free perfused rat liver. Eur J Biochem (1975) 1.21
Decreased flux through pyruvate dehydrogenase during calcium ion movements induced by vasopressin, alpha-adrenergic agonists and the ionophore A23187 in perfused rat liver. Biochem J (1983) 1.20
Chemical depletion of glutathione in vivo. Methods Enzymol (1981) 1.20
State of oxidation-reduction and state of binding in the cytosolic NADH-system as disclosed by equilibration with extracellular lactate-pyruvate in hemoglobin-free perfused rat liver. Eur J Biochem (1972) 1.19
Mitochondrial and cytosolic ATP/ADP ratios in rat liver in vivo. Biochem J (1981) 1.19
Protection against peroxynitrite. FEBS Lett (1999) 1.19
Activation of transcription factor AP-2 mediates UVA radiation- and singlet oxygen-induced expression of the human intercellular adhesion molecule 1 gene. Proc Natl Acad Sci U S A (1996) 1.19
Hepatic mitochondrial and cytosolic glutathione content and the subcellular distribution of GSH-S-transferases. FEBS Lett (1979) 1.18
ATP-dependent S-(2,4-dinitrophenyl)glutathione transport in canalicular plasma membrane vesicles from rat liver. J Biol Chem (1991) 1.16
Arachidonic acid stimulates cell growth and forms a novel oxygenated metabolite in Candida albicans. Biochim Biophys Acta (2000) 1.14
Analysis of the stereochemistry of lipoxygenase-derived hydroxypolyenoic fatty acids by means of chiral phase high-pressure liquid chromatography. Anal Biochem (1987) 1.14
Increased frequency of a null-allele for NAD(P)H: quinone oxidoreductase in patients with urological malignancies. Pharmacogenetics (1997) 1.14
Peroxynitrite activates the phosphoinositide 3-kinase/Akt pathway in human skin primary fibroblasts. Biochem J (2000) 1.14
Macular pigments lutein and zeaxanthin as blue light filters studied in liposomes. Arch Biochem Biophys (2001) 1.13
Regulation of flux through glutaminase and glutamine synthetase in isolated perfused rat liver. Biochim Biophys Acta (1983) 1.13
Phospholipase A(2)s and lipid peroxidation. Biochim Biophys Acta (2000) 1.12
Mitogen-activated protein kinase (p38-, JNK-, ERK-) activation pattern induced by extracellular and intracellular singlet oxygen and UVA. Eur J Biochem (1999) 1.12
Reactive oxygen species associated with cell differentiation in Neurospora crassa. Free Radic Biol Med (1993) 1.12
Carotenoids, tocopherols and thiols as biological singlet molecular oxygen quenchers. Biochem Soc Trans (1990) 1.12
The maturational breakdown of mitochondria in reticulocytes. Biochim Biophys Acta (1986) 1.12
cis-trans isomers of lycopene and beta-carotene in human serum and tissues. Arch Biochem Biophys (1992) 1.11
Plasma antioxidants and longevity: a study on healthy centenarians. Free Radic Biol Med (2000) 1.11
Glutathione disulfide (GSSG) efflux from cells and tissues. Methods Enzymol (1984) 1.10
Oxidation of glutathione by the superoxide radical to the disulfide and the sulfonate yielding singlet oxygen. Eur J Biochem (1983) 1.10
Singlet oxygen may mediate the ultraviolet A-induced synthesis of interstitial collagenase. J Invest Dermatol (1995) 1.10
Role of alcohol dehydrogenase activity and the acetaldehyde in ethanol- induced ethane and pentane production by isolated perfused rat liver. Biochem J (1982) 1.09
Toxic and signaling effects of photochemically or chemically generated singlet oxygen in biological systems. Biol Chem (1997) 1.09
Plasma levels of lipophilic antioxidants in very old patients with type 2 diabetes. Diabetes Metab Res Rev (2000) 1.08
Mitochondrial and cytosolic ATP/ADP ratios in isolated hepatocytes. A comparison of the digitonin method and the non-aqueous fractionation procedure. Biochem J (1980) 1.08
The stereochemistry of the reactions of lipoxygenases and their metabolites. Proposed nomenclature of lipoxygenases and related enzymes. Adv Enzymol Relat Areas Mol Biol (1986) 1.08
A lipoxygenase in rabbit reticulocytes which attacks phospholipids and intact mitochondria. FEBS Lett (1975) 1.07
Protection by selenoprotein P in human plasma against peroxynitrite-mediated oxidation and nitration. Biol Chem (1998) 1.07
Selective upregulation of inducible nitric oxide synthase (iNOS) by lipopolysaccharide (LPS) and cytokines in microglia: in vitro and in vivo studies. Glia (2000) 1.07
Ebselen prevents early alcohol-induced liver injury in rats. Free Radic Biol Med (2001) 1.06
Cardiac transport of glutathione disulfide and S-conjugate. Studies with isolated perfused rat heart during hydroperoxide metabolism. J Biol Chem (1984) 1.06
Association of NAD(P)H:quinone oxidoreductase (NQO1) null with numbers of basal cell carcinomas: use of a multivariate model to rank the relative importance of this polymorphism and those at other relevant loci. Carcinogenesis (1999) 1.06
Human fibroblasts release low amounts of reactive oxygen species in response to the potent phagocyte stimulants, serum-treated zymosan, N-formyl-methionyl-leucyl-phenylalanine, leukotriene B4 or 12-O-tetradecanoylphorbol 13-acetate. Biol Chem Hoppe Seyler (1990) 1.05
Quantification of the alpha- and gamma-tocopherol metabolites 2,5,7, 8-tetramethyl-2-(2'-carboxyethyl)-6-hydroxychroman and 2,7, 8-trimethyl-2-(2'-carboxyethyl)-6-hydroxychroman in human serum. Anal Biochem (1999) 1.05
The protection by ascorbate and glutathione against microsomal lipid peroxidation is dependent on vitamin E. Eur J Biochem (1988) 1.05
Carotenoid mixtures protect multilamellar liposomes against oxidative damage: synergistic effects of lycopene and lutein. FEBS Lett (1998) 1.05
Nitric oxide-mediated inhibition of androgen receptor activity: possible implications for prostate cancer progression. Oncogene (2006) 1.04
The selenoenzyme phospholipid hydroperoxide glutathione peroxidase controls the activity of the 15-lipoxygenase with complex substrates and preserves the specificity of the oxygenation products. J Biol Chem (1996) 1.04
Ebselen: prospective therapy for cerebral ischaemia. Expert Opin Investig Drugs (2000) 1.04
Singlet oxygen induced DNA damage and mutagenicity in a single-stranded SV40-based shuttle vector. Photochem Photobiol (1992) 1.04
Deficient metabolic utilization of hydrogen peroxide in Trypanosoma cruzi. Biochem J (1980) 1.03
A role of mitochondrial glutathione peroxidase in modulating mitochondrial oxidations in liver. Eur J Biochem (1978) 1.03
Contribution of nitric oxide synthase to luminol-dependent chemiluminescence generated by phorbol-ester-activated Kupffer cells. Biochem J (1991) 1.03
Oxidative stress: excited oxygen species and enzyme activity. Adv Enzyme Regul (1985) 1.03
Profiles of antioxidants in human plasma. Free Radic Biol Med (2001) 1.02
Hepatic calcium efflux during cytochrome P-450-dependent drug oxidations at the endoplasmic reticulum in intact liver. Proc Natl Acad Sci U S A (1981) 1.02
Evidence that singlet oxygen-induced human T helper cell apoptosis is the basic mechanism of ultraviolet-A radiation phototherapy. J Exp Med (1997) 1.02
Carotenoids and carotenoids plus vitamin E protect against ultraviolet light-induced erythema in humans. Am J Clin Nutr (2000) 1.01
Plasma levels of vitamin E and carotenoids are decreased in patients with Nonalcoholic Steatohepatitis (NASH). Eur J Med Res (2011) 1.01
DNA damage by peroxynitrite characterized with DNA repair enzymes. Nucleic Acids Res (1996) 1.01
Hepatic glutamine metabolism under the influence of the portal ammonia concentration in the perfused rat liver. Eur J Biochem (1979) 1.01
Lowered amounts of the tissue-specific transcription factor LFB1 (HNF1) correlate with decreased levels of glutathione S-transferase alpha messenger RNA in human renal cell carcinoma. Cancer Res (1994) 1.00