Published in EMBO J on August 01, 2001
Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation. Cell (2008) 6.07
Multimodal activation of the ubiquitin ligase SCF by Nedd8 conjugation. Mol Cell (2008) 4.09
Cullin-RING ubiquitin ligases: global regulation and activation cycles. Cell Div (2008) 2.63
Distinct protein degradation mechanisms mediated by Cul1 and Cul3 controlling Ci stability in Drosophila eye development. Genes Dev (2002) 2.55
Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery. J Virol (2002) 2.31
The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice. J Cell Biol (2001) 2.26
Function and regulation of protein neddylation. 'Protein modifications: beyond the usual suspects' review series. EMBO Rep (2008) 2.19
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification. Mol Cell (2009) 1.98
Arabidopsis SGT1b is required for SCF(TIR1)-mediated auxin response. Plant Cell (2003) 1.96
Autoinhibitory regulation of SCF-mediated ubiquitination by human cullin 1's C-terminal tail. Proc Natl Acad Sci U S A (2008) 1.92
CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex. Proc Natl Acad Sci U S A (2002) 1.89
Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteins. Mol Cell Biol (2004) 1.86
Regulation of the Nrf2-Keap1 antioxidant response by the ubiquitin proteasome system: an insight into cullin-ring ubiquitin ligases. Antioxid Redox Signal (2010) 1.85
Ubiquitination and auxin signaling: a degrading story. Plant Cell (2002) 1.85
Regulation of neddylation and deneddylation of cullin1 in SCFSkp2 ubiquitin ligase by F-box protein and substrate. Proc Natl Acad Sci U S A (2006) 1.81
The COP9 signalosome interacts physically with SCF COI1 and modulates jasmonate responses. Plant Cell (2003) 1.80
The NEDD8 Conjugation Pathway and Its Relevance in Cancer Biology and Therapy. Genes Cancer (2010) 1.80
Human papillomavirus type 16 E7 oncoprotein associates with the cullin 2 ubiquitin ligase complex, which contributes to degradation of the retinoblastoma tumor suppressor. J Virol (2007) 1.73
An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells. EMBO Rep (2002) 1.71
Arabidopsis E2Fc functions in cell division and is degraded by the ubiquitin-SCF(AtSKP2) pathway in response to light. Plant Cell (2002) 1.67
Targeted silencing of Jab1/Csn5 in human cells downregulates SCF activity through reduction of F-box protein levels. BMC Biochem (2006) 1.62
Arabidopsis CAND1, an unmodified CUL1-interacting protein, is involved in multiple developmental pathways controlled by ubiquitin/proteasome-mediated protein Degradation. Plant Cell (2004) 1.60
SCRAPPER-dependent ubiquitination of active zone protein RIM1 regulates synaptic vesicle release. Cell (2007) 1.60
Arabidopsis ETA2, an apparent ortholog of the human cullin-interacting protein CAND1, is required for auxin responses mediated by the SCF(TIR1) ubiquitin ligase. Plant Cell (2004) 1.58
Dysregulation of protein modification by ISG15 results in brain cell injury. Genes Dev (2002) 1.57
Control of cell growth by the SCF and APC/C ubiquitin ligases. Curr Opin Cell Biol (2009) 1.55
Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome. EMBO J (2003) 1.53
Attachment of the ubiquitin-related protein Urm1p to the antioxidant protein Ahp1p. Eukaryot Cell (2003) 1.52
Structural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1. EMBO J (2005) 1.48
Urmylation: a ubiquitin-like pathway that functions during invasive growth and budding in yeast. Mol Biol Cell (2003) 1.47
Disruption of the COP9 signalosome Csn2 subunit in mice causes deficient cell proliferation, accumulation of p53 and cyclin E, and early embryonic death. Mol Cell Biol (2003) 1.46
SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation. J Biol Chem (2008) 1.40
Role of the MPN subunits in COP9 signalosome assembly and activity, and their regulatory interaction with Arabidopsis Cullin3-based E3 ligases. Plant Cell (2007) 1.40
Arabidopsis has two redundant Cullin3 proteins that are essential for embryo development and that interact with RBX1 and BTB proteins to form multisubunit E3 ubiquitin ligase complexes in vivo. Plant Cell (2005) 1.39
CIF-1, a shared subunit of the COP9/signalosome and eukaryotic initiation factor 3 complexes, regulates MEL-26 levels in the Caenorhabditis elegans embryo. Mol Cell Biol (2007) 1.38
Contrasting proteome biology and functional heterogeneity of the 20 S proteasome complexes in mammalian tissues. Mol Cell Proteomics (2008) 1.29
Structural basis for a reciprocal regulation between SCF and CSN. Cell Rep (2012) 1.28
CAND1-mediated substrate adaptor recycling is required for efficient repression of Nrf2 by Keap1. Mol Cell Biol (2006) 1.27
The human Dcn1-like protein DCNL3 promotes Cul3 neddylation at membranes. Proc Natl Acad Sci U S A (2009) 1.24
Characterization of the last subunit of the Arabidopsis COP9 signalosome: implications for the overall structure and origin of the complex. Plant Cell (2003) 1.23
Survival defects of Cryptococcus neoformans mutants exposed to human cerebrospinal fluid result in attenuated virulence in an experimental model of meningitis. Infect Immun (2010) 1.22
Deconjugation of Nedd8 from Cul1 is directly regulated by Skp1-F-box and substrate, and the COP9 signalosome inhibits deneddylated SCF by a noncatalytic mechanism. J Biol Chem (2012) 1.22
The Cullin3 ubiquitin ligase functions as a Nedd8-bound heterodimer. Mol Biol Cell (2006) 1.22
Cul7/p185/p193 binding to simian virus 40 large T antigen has a role in cellular transformation. J Virol (2004) 1.19
Rac GTPase instructs nuclear factor-kappaB activation by conveying the SCF complex and IkBalpha to the ruffling membranes. Mol Biol Cell (2003) 1.18
14-3-3eta is a novel regulator of parkin ubiquitin ligase. EMBO J (2005) 1.18
Regulation of abiotic stress signal transduction by E3 ubiquitin ligases in Arabidopsis. Mol Cells (2011) 1.16
CSN- and CAND1-dependent remodelling of the budding yeast SCF complex. Nat Commun (2013) 1.14
In vivo interference with Skp1 function leads to genetic instability and neoplastic transformation. Mol Cell Biol (2002) 1.13
A new CULLIN 1 mutant has altered responses to hormones and light in Arabidopsis. Plant Physiol (2006) 1.12
CSN1 N-terminal-dependent activity is required for Arabidopsis development but not for Rub1/Nedd8 deconjugation of cullins: a structure-function study of CSN1 subunit of COP9 signalosome. Mol Biol Cell (2002) 1.11
C. elegans CAND-1 regulates cullin neddylation, cell proliferation and morphogenesis in specific tissues. Dev Biol (2010) 1.11
The Arabidopsis CSN5A and CSN5B subunits are present in distinct COP9 signalosome complexes, and mutations in their JAMM domains exhibit differential dominant negative effects on development. Plant Cell (2004) 1.10
Ubiquitin ligase activity of Cul3-KLHL7 protein is attenuated by autosomal dominant retinitis pigmentosa causative mutation. J Biol Chem (2011) 1.09
Dysfunction of the ubiquitin proteasome and ubiquitin-like systems in schizophrenia. Neuropsychopharmacology (2013) 1.09
Role of the NEDD8 modification of Cul2 in the sequential activation of ECV complex. Neoplasia (2006) 1.08
Saccharomyces cerevisiae ubiquitin-like protein Rub1 conjugates to cullin proteins Rtt101 and Cul3 in vivo. Biochem J (2004) 1.07
Cullin neddylation and substrate-adaptors counteract SCF inhibition by the CAND1-like protein Lag2 in Saccharomyces cerevisiae. EMBO J (2009) 1.07
Cdc34 C-terminal tail phosphorylation regulates Skp1/cullin/F-box (SCF)-mediated ubiquitination and cell cycle progression. Biochem J (2007) 1.04
SCCRO (DCUN1D1) promotes nuclear translocation and assembly of the neddylation E3 complex. J Biol Chem (2011) 1.02
A new ubiquitin ligase involved in p57KIP2 proteolysis regulates osteoblast cell differentiation. EMBO Rep (2008) 1.02
Characterization of the VIER F-BOX PROTEINE genes from Arabidopsis reveals their importance for plant growth and development. Plant Cell (2007) 1.01
Ankyrin repeat and SOCS box containing protein 4 (Asb-4) interacts with GPS1 (CSN1) and inhibits c-Jun NH2-terminal kinase activity. Cell Signal (2007) 0.96
COPing with hypoxia. Semin Cell Dev Biol (2005) 0.96
Posttranslational modifications of proteins in the pathobiology of medically relevant fungi. Eukaryot Cell (2011) 0.96
Ubiquitin pathway in VHL cancer syndrome. Neoplasia (2006) 0.94
Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway. Mol Syst Biol (2009) 0.94
Playing Tag with HIF: The VHL Story. J Biomed Biotechnol (2002) 0.93
Dual effects of IkappaB kinase beta-mediated phosphorylation on p105 Fate: SCF(beta-TrCP)-dependent degradation and SCF(beta-TrCP)-independent processing. Mol Cell Biol (2004) 0.93
Cross talk in hormonally regulated gene transcription through induction of estrogen receptor ubiquitylation. Mol Cell Biol (2005) 0.91
Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy. BMC Cell Biol (2009) 0.90
The COP9 signalosome is required for autophagy, proteasome-mediated proteolysis, and cardiomyocyte survival in adult mice. Circ Heart Fail (2013) 0.90
Adenovirus E1A inhibits SCF(Fbw7) ubiquitin ligase. J Biol Chem (2009) 0.89
CRL Ubiquitin Ligases and DNA Damage Response. Front Oncol (2012) 0.89
Twists and turns in ubiquitin-like protein conjugation cascades. Protein Sci (2011) 0.88
Auxin responses in mutants of the Arabidopsis CONSTITUTIVE PHOTOMORPHOGENIC9 signalosome. Plant Physiol (2008) 0.88
The NEDD8-activating enzyme inhibitor, MLN4924, cooperates with TRAIL to augment apoptosis through facilitating c-FLIP degradation in head and neck cancer cells. Mol Cancer Ther (2011) 0.87
A fluorescent bimolecular complementation screen reveals MAF1, RNF7 and SETD3 as PCNA-associated proteins in human cells. Cell Cycle (2015) 0.87
Neddylation dysfunction in Alzheimer's disease. J Cell Mol Med (2012) 0.86
Recruitment of the inhibitor Cand1 to the cullin substrate adaptor site mediates interaction to the neddylation site. Mol Biol Cell (2010) 0.86
Targeting Cullin-RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation. Biochem J (2015) 0.85
Substrate binding promotes formation of the Skp1-Cul1-Fbxl3 (SCF(Fbxl3)) protein complex. J Biol Chem (2013) 0.83
Characterization of the role of COP9 signalosome in regulating cullin E3 ubiquitin ligase activity. Mol Biol Cell (2011) 0.83
DCNL1 functions as a substrate sensor and activator of cullin 2-RING ligase. Mol Cell Biol (2013) 0.82
Modification by ubiquitin-like proteins: significance in apoptosis and autophagy pathways. Int J Mol Sci (2012) 0.82
Quantitative characterization and analysis of the dynamic NF-κB response in microglia. BMC Bioinformatics (2011) 0.81
De novo DNA methyltransferase DNMT3b interacts with NEDD8-modified proteins. J Biol Chem (2010) 0.81
Oncogenic function of SCCRO5/DCUN1D5 requires its Neddylation E3 activity and nuclear localization. Clin Cancer Res (2013) 0.81
CSN-mediated deneddylation differentially modulates Ci(155) proteolysis to promote Hedgehog signalling responses. Nat Commun (2011) 0.80
Crosstalk between the NF-kappaB activating IKK-complex and the CSN signalosome. J Cell Mol Med (2009) 0.80
Brap2 regulates temporal control of NF-κB localization mediated by inflammatory response. PLoS One (2013) 0.80
Identification of NAE Inhibitors Exhibiting Potent Activity in Leukemia Cells: Exploring the Structural Determinants of NAE Specificity. ACS Med Chem Lett (2011) 0.79
Gene expression and proteomic analysis of the formation of Phakopsora pachyrhizi appressoria. BMC Genomics (2012) 0.78
Graded Proteasome Dysfunction in Caenorhabditis elegans Activates an Adaptive Response Involving the Conserved SKN-1 and ELT-2 Transcription Factors and the Autophagy-Lysosome Pathway. PLoS Genet (2016) 0.78
The human COP9 signalosome protects ubiquitin-conjugating enzyme 3 (UBC3/Cdc34) from beta-transducin repeat-containing protein (betaTrCP)-mediated degradation. J Biol Chem (2010) 0.77
Structural architecture of Galdieria sulphuraria DCN1L. Proteins (2011) 0.77
Neddylation and CAND1 independently stimulate SCF ubiquitin ligase activity in Candida albicans. Eukaryot Cell (2011) 0.77
Cullin-RING ligases in regulation of autophagy. Cell Div (2016) 0.75
Squamous Cell Carcinoma-related Oncogene (SCCRO) Family Members Regulate Cell Growth and Proliferation through Their Cooperative and Antagonistic Effects on Cullin Neddylation. J Biol Chem (2016) 0.75
COP9-Signalosome deneddylase activity is enhanced by simultaneous neddylation: insights into the regulation of an enzymatic protein complex. Cell Div (2015) 0.75
The ubiquitin system. Annu Rev Biochem (1998) 43.36
The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol (1996) 22.30
NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol (1998) 21.48
SCF and Cullin/Ring H2-based ubiquitin ligases. Annu Rev Cell Dev Biol (1999) 9.54
The 26S proteasome: a molecular machine designed for controlled proteolysis. Annu Rev Biochem (1999) 8.97
The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro. Genes Dev (1999) 6.56
Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase. Science (1999) 6.38
A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly. Cell (1999) 6.04
Identification of the receptor component of the IkappaBalpha-ubiquitin ligase. Nature (1998) 4.89
ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. Mol Cell (1999) 4.53
Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34. Genes Dev (1999) 4.17
The F-box protein family. Genome Biol (2000) 4.00
Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway. Cell (1997) 3.91
The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27. Nat Cell Biol (2001) 3.87
Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev (1998) 3.84
Evolution and function of ubiquitin-like protein-conjugation systems. Nat Cell Biol (2000) 3.76
Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha. Mol Cell Biol (2000) 3.51
Ubiquitin-like proteins: new wines in new bottles. Gene (2000) 3.46
A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling pathways. Genes Dev (1999) 3.38
A novel protein modification pathway related to the ubiquitin system. EMBO J (1998) 3.36
SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex. Mol Cell (1999) 3.19
Mechanistic aspects of NF-kappa B regulation: the emerging role of phosphorylation and proteolysis. Immunity (1995) 2.93
A new NEDD8-ligating system for cullin-4A. Genes Dev (1998) 2.82
Ubiquitin and its kin: how close are the family ties? Trends Cell Biol (2000) 2.81
The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2. Genes Dev (1999) 2.78
A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination. Proc Natl Acad Sci U S A (2000) 2.69
Covalent modification of all members of human cullin family proteins by NEDD8. Oncogene (1999) 2.67
Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization. J Biol Chem (2000) 2.53
The ubiquitin-related protein RUB1 and auxin response in Arabidopsis. Science (1998) 2.42
Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast. EMBO J (2000) 2.27
Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway. J Biol Chem (1999) 2.15
The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1. Mol Cell Biol (2000) 2.09
There's the rub: a novel ubiquitin-like modification linked to cell cycle regulation. Genes Dev (1998) 2.00
Function of the ubiquitin-proteasome pathway in auxin response. Trends Biochem Sci (2000) 1.88
Homodimer of two F-box proteins betaTrCP1 or betaTrCP2 binds to IkappaBalpha for signal-dependent ubiquitination. J Biol Chem (2000) 1.73
Modification of cullin-1 by ubiquitin-like protein Nedd8 enhances the activity of SCF(skp2) toward p27(kip1). Biochem Biophys Res Commun (2000) 1.68
The amyloid precursor protein-binding protein APP-BP1 drives the cell cycle through the S-M checkpoint and causes apoptosis in neurons. J Biol Chem (2000) 1.52
Reconstitution of p53-ubiquitinylation reactions from purified components: the role of human ubiquitin-conjugating enzyme UBC4 and E6-associated protein (E6AP). Proc Natl Acad Sci U S A (1995) 1.29
IkappaB kinases: kinsmen with different crafts. Science (1999) 1.19
Lac repressor-operator interaction. I. Equilibrium studies. J Mol Biol (1970) 13.32
The International Registry of Acute Aortic Dissection (IRAD): new insights into an old disease. JAMA (2000) 12.26
Effect of a new immunosuppressive agent, FK 506, on heterotopic cardiac allotransplantation in the rat. Transplant Proc (1987) 12.04
Structural parts involved in activation and inactivation of the sodium channel. Nature (1989) 8.72
Existence of distinct sodium channel messenger RNAs in rat brain. Nature (1986) 7.87
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat Genet (2000) 7.83
New topoisomerase essential for chromosome segregation in E. coli. Cell (1990) 7.19
On the process of cellular division in Escherichia coli: a series of mutants of E. coli altered in the penicillin-binding proteins. Proc Natl Acad Sci U S A (1978) 6.93
Cell-free translation reconstituted with purified components. Nat Biotechnol (2001) 6.55
A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection. Nature (1997) 5.55
Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1. Nature (1994) 5.00
A two-step mechanism for the interaction of estradiol with rat uterus. Proc Natl Acad Sci U S A (1968) 4.77
On the process of cellular division in Escherichia coli: a mutant of E. coli lacking a murein-lipoprotein. Proc Natl Acad Sci U S A (1977) 4.58
Hypertension caused by a truncated epithelial sodium channel gamma subunit: genetic heterogeneity of Liddle syndrome. Nat Genet (1995) 4.45
Mutants of Escherichia coli lacking in highly penicillin-sensitive D-alanine carboxypeptidase activity. Proc Natl Acad Sci U S A (1977) 4.44
Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression. Proc Natl Acad Sci U S A (1998) 4.40
Incomplete flagellar structures in nonflagellate mutants of Salmonella typhimurium. J Bacteriol (1978) 4.07
Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery. J Biol Chem (2000) 4.02
Helicobacter pylori CagA protein can be tyrosine phosphorylated in gastric epithelial cells. J Exp Med (2000) 3.74
Acetylcholine releases endothelium-derived hyperpolarizing factor and EDRF from rat blood vessels. Br J Pharmacol (1988) 3.66
Gene fliA encodes an alternative sigma factor specific for flagellar operons in Salmonella typhimurium. Mol Gen Genet (1990) 3.49
On the process of cellular division in Escherichia coli: nucleotide sequence of the gene for penicillin-binding protein 3. Mol Gen Genet (1983) 3.43
Microarray fabrication with covalent attachment of DNA using bubble jet technology. Nat Biotechnol (2000) 3.38
Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas. Nat Genet (1998) 3.38
A novel transcriptional regulation mechanism in the flagellar regulon of Salmonella typhimurium: an antisigma factor inhibits the activity of the flagellum-specific sigma factor, sigma F. Mol Microbiol (1992) 3.31
Primary structure of the alpha-subunit of transducin and its relationship to ras proteins. Nature (1985) 3.28
Purification and characterization of a novel type of fimbriae from the oral anaerobe Bacteroides gingivalis. J Bacteriol (1984) 3.27
A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors. Proc Natl Acad Sci U S A (1999) 3.26
The membrane properties of the smooth muscle cells of the rabbit main pulmonary artery. J Physiol (1977) 3.24
Sialic acid species as a determinant of the host range of influenza A viruses. J Virol (2000) 3.10
Unaltered secretion of beta-amyloid precursor protein in gelatinase A (matrix metalloproteinase 2)-deficient mice. J Biol Chem (1997) 3.09
Excitation-contraction coupling in the smooth muscle cells of the rabbit main pulmonary artery. J Physiol (1977) 3.06
Sarin poisoning in Tokyo subway. Lancet (1995) 3.06
Genetic mapping with SNP markers in Drosophila. Nat Genet (2001) 3.02
Involvement of interleukin-8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor necrosis factor alpha-dependent angiogenesis. Mol Cell Biol (1997) 3.02
Expression of functional sodium channels from cloned cDNA. Nature (1986) 2.95
Excitation--contraction coupling in smooth muscle cells of the guinea-pig mesenteric artery. J Physiol (1981) 2.92
Murein-lipoprotein of Escherichia coli: a protein involved in the stabilization of bacterial cell envelope. Mol Gen Genet (1978) 2.84
Eight genes in region 5 that form an operon are essential for invasion of epithelial cells by Shigella flexneri 2a. J Bacteriol (1993) 2.82
Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase. Nat Genet (1999) 2.81
Hepatitis B e antigen and infectivity of hepatitis B virus. J Infect Dis (1977) 2.80
Phase-field model for binary alloys. Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics (1999) 2.79
The Arabidopsis AHK4 histidine kinase is a cytokinin-binding receptor that transduces cytokinin signals across the membrane. Plant Cell Physiol (2001) 2.79
Incomplete flagellar structures in Escherichia coli mutants. J Bacteriol (1981) 2.77
Long-term clinical outcomes after unprotected left main trunk percutaneous revascularization in 279 patients. Circulation (2001) 2.77
A single point mutation confers tetrodotoxin and saxitoxin insensitivity on the sodium channel II. FEBS Lett (1989) 2.73
Role for the class A macrophage scavenger receptor in the phagocytosis of apoptotic thymocytes in vitro. Proc Natl Acad Sci U S A (1996) 2.69
Innervation and properties of the smooth muscle of the dog trachea. Jpn J Physiol (1976) 2.65
Factors modifying contraction-relaxation cycle in vascular smooth muscles. Am J Physiol (1982) 2.63
Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype. Cancer Res (1999) 2.62
Cortical mapping of gait in humans: a near-infrared spectroscopic topography study. Neuroimage (2001) 2.59
The role of cAMP in flagellation of Salmonella typhimurium. Mol Gen Genet (1976) 2.54
Purification and characterization of DNA topoisomerase IV in Escherichia coli. J Biol Chem (1992) 2.50
Considerable time from the onset of plaque rupture and/or thrombi until the onset of acute myocardial infarction in humans: coronary angiographic findings within 1 week before the onset of infarction. Circulation (2000) 2.42
Isolation and characterization of fra-2, an additional member of the fos gene family. Proc Natl Acad Sci U S A (1990) 2.40
Rhamnolipids produced by Pseudomonas aeruginosa grown on n-paraffin (mixture of C 12 , C 13 and C 14 fractions). J Antibiot (Tokyo) (1971) 2.39
Specific inhibition of adherence of an oral strain of Bacteroides gingivalis 381 to epithelial cells by monoclonal antibodies against the bacterial fimbriae. Arch Oral Biol (1988) 2.39
Differences in sialic acid-galactose linkages in the chicken egg amnion and allantois influence human influenza virus receptor specificity and variant selection. J Virol (1997) 2.38
Diverse molecular interactions of the hnRNP K protein. FEBS Lett (1997) 2.35
Localization of a novel v-erbB-related gene, c-erbB-2, on human chromosome 17 and its amplification in a gastric cancer cell line. Mol Cell Biol (1986) 2.33
Gene organization in the region containing a new gene involved in chromosome partition in Escherichia coli. J Bacteriol (1988) 2.31
The macrophage scavenger receptor type A is expressed by activated macrophages and protects the host against lethal endotoxic shock. J Exp Med (1997) 2.28
Metabolism of pentachlorophenol by a soil microbe. J Environ Sci Health B (1977) 2.28
Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast. EMBO J (2000) 2.27
Differences and similarities in the noradrenaline- and caffeine-induced mechanical responses in the rabbit mesenteric artery. J Physiol (1983) 2.26
Network theory in autoimmunity. In vitro suppression of serum anti-DNA antibody binding to DNA by anti-idiotypic antibody in systemic lupus erythematosus. J Clin Invest (1981) 2.24
The effects of acetylcholine on the membrane and contractile properties of smooth muscle cells of the rabbit superior mesenteric artery. Br J Pharmacol (1978) 2.23
Surgical significance of anatomic variations of the hepatic artery. Am J Surg (1971) 2.23
Synthetic ColE1 plasmids carrying genes for cell division in Escherichia coli. Plasmid (1977) 2.22
Unitary nature of regenerative potentials recorded from circular smooth muscle of guinea-pig antrum. J Physiol (1999) 2.18
Cultivated corneal epithelial stem cell transplantation in ocular surface disorders. Ophthalmology (2001) 2.16
Effects of endogenous and exogenous noradrenaline on the smooth muscle of guinea-pig mesenteric vein. J Physiol (1981) 2.16
In vitro peptidoglycan polymerization catalysed by penicillin binding protein 1b of Escherichia coli K-12. FEBS Lett (1980) 2.14
Properties of spontaneous depolarizations in circular smooth muscle cells of rabbit urethra. Br J Pharmacol (1996) 2.11
Congenital progressive muscular dystrophy of the Fukuyama type - clinical, genetic and pathological considerations. Brain Dev (1981) 2.11
Absence of messenger ribonucleic acid specific for flagellin in non-flagellate mutants of Salmonella. J Mol Biol (1975) 2.10
Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability. Cancer Res (1999) 2.09
Nucleotide sequence of the streptothricin acetyltransferase gene from Streptomyces lavendulae and its expression in heterologous hosts. J Bacteriol (1987) 2.08
Primary structure of chicken skeletal muscle and fibroblast alpha-actinins deduced from cDNA sequences. Eur J Biochem (1988) 2.08
White ball appearance in endoscopic ligation of bleeding esophageal varices. Gastrointest Endosc (1998) 2.08
Role of the scavenger receptor MARCO in alveolar macrophage binding of unopsonized environmental particles. J Exp Med (1999) 2.08
Point mutations in the WD40 domain of Eed block its interaction with Ezh2. Mol Cell Biol (1998) 2.08
Role of Norwalk virus in outbreaks of nonbacterial gastroenteritis. J Infect Dis (1979) 2.05
Structure and function of chicken gizzard myosin. J Biochem (1978) 2.05
Streptococcal cytoplasmic pH is regulated by changes in amount and activity of a proton-translocating ATPase. J Biol Chem (1986) 2.03
Effects of combination treatment with FK506 and cyclosporine on survival time and vascular changes in renal-allograft-recipient dogs. Transplantation (1989) 2.03
Adrenergic transmissions in the guinea-pig mesenteric artery and their cholinergic modulations. J Physiol (1981) 2.02
LST-2, a human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers. Gastroenterology (2001) 2.02
Sequence of an intestinal cDNA encoding human gastric inhibitory polypeptide precursor. Proc Natl Acad Sci U S A (1987) 2.02
Catabolite repression of cellulase formation in Trichoderma viride. J Biochem (1972) 2.00
Walking speed as a good predictor for the onset of functional dependence in a Japanese rural community population. Age Ageing (2000) 1.99
Genetic heterogeneity of the human glutathione transferases: a complex of gene families. Pharmacol Ther (1990) 1.99
Human soluble IL-6 receptor: its detection and enhanced release by HIV infection. J Immunol (1992) 1.99
Inversion of the membrane topology of SecG coupled with SecA-dependent preprotein translocation. Cell (1996) 1.98
Predictors for functional decline among nondisabled older Japanese living in a community during a 3-year follow-up. J Am Geriatr Soc (2000) 1.98
Hyperpolarization of arterial smooth muscle induced by endothelial humoral substances. Am J Physiol (1991) 1.98
In vivo klotho gene delivery protects against endothelial dysfunction in multiple risk factor syndrome. Biochem Biophys Res Commun (2000) 1.97
Expression of glucose transporter-1 in human gastric carcinoma: association with tumor aggressiveness, metastasis, and patient survival. Cancer (2001) 1.96
Some electrical properties of the endothelium-dependent hyperpolarization recorded from rat arterial smooth muscle cells. J Physiol (1989) 1.96