PubRank

J Ortín

Author PubWeight™ 107.84‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The quasispecies (extremely heterogeneous) nature of viral RNA genome populations: biological relevance--a review. Gene 1985 3.42
2 Influenza virus NS1 protein inhibits pre-mRNA splicing and blocks mRNA nucleocytoplasmic transport. EMBO J 1994 3.26
3 Multiple genetic variants arise in the course of replication of foot-and-mouth disease virus in cell culture. Virology 1983 3.04
4 Eukaryotic translation initiation factor 4GI is a cellular target for NS1 protein, a translational activator of influenza virus. Mol Cell Biol 2000 2.48
5 Expression in mammalian cells of a gene from Streptomyces alboniger conferring puromycin resistance. Nucleic Acids Res 1986 2.45
6 Nucleotide sequence heterogeneity of the RNA from a natural population of foot-and-mouth-disease virus. Gene 1980 2.44
7 Influenza virus NS1 protein enhances the rate of translation initiation of viral mRNAs. J Virol 1995 2.16
8 Efficient transformation of mammalian cells with constructs containing a puromycin-resistance marker. Gene 1988 2.03
9 The mammalian staufen protein localizes to the somatodendritic domain of cultured hippocampal neurons: implications for its involvement in mRNA transport. J Neurosci 1999 2.03
10 Complex structure of the nuclear translocation signal of influenza virus polymerase PA subunit. J Gen Virol 1994 2.03
11 Individual expression of influenza virus PA protein induces degradation of coexpressed proteins. J Virol 1995 2.02
12 Distinct regions of influenza virus PB1 polymerase subunit recognize vRNA and cRNA templates. EMBO J 1999 2.00
13 PA subunit from influenza virus polymerase complex interacts with a cellular protein with homology to a family of transcriptional activators. J Virol 2001 1.98
14 Genetic variability of Hong Kong (H3N2) influenza viruses: spontaneous mutations and their location in the viral genome. Gene 1980 1.95
15 Monoclonal antibodies against influenza virus PB2 and NP polypeptides interfere with the initiation step of viral mRNA synthesis in vitro. J Virol 1994 1.93
16 Identification of two separate domains in the influenza virus PB1 protein involved in the interaction with the PB2 and PA subunits: a model for the viral RNA polymerase structure. Nucleic Acids Res 1996 1.89
17 Ultrastructural and functional analyses of recombinant influenza virus ribonucleoproteins suggest dimerization of nucleoprotein during virus amplification. J Virol 2000 1.86
18 Establishment of cell lines persistently infected with foot-and-mouth disease virus. Virology 1985 1.84
19 Synthesis of biologically active influenza virus core proteins using a vaccinia virus-T7 RNA polymerase expression system. J Gen Virol 1994 1.83
20 The amino-terminal one-third of the influenza virus PA protein is responsible for the induction of proteolysis. J Virol 1996 1.79
21 Influenza virus NS1 protein interacts with viral transcription-replication complexes in vivo. J Gen Virol 1997 1.79
22 Influenza virus naked RNA can be expressed upon transfection into cells co-expressing the three subunits of the polymerase and the nucleoprotein from simian virus 40 recombinant viruses. J Gen Virol 1993 1.74
23 A human sequence homologue of Staufen is an RNA-binding protein that is associated with polysomes and localizes to the rough endoplasmic reticulum. Mol Cell Biol 1999 1.74
24 The influenza A virus PB2 polymerase subunit is required for the replication of viral RNA. J Virol 1997 1.71
25 The replication activity of influenza virus polymerase is linked to the capacity of the PA subunit to induce proteolysis. J Virol 2000 1.69
26 Evolution of the nucleotide sequence of influenza virus RNA segment 7 during drift of the H3N2 subtype. Gene 1983 1.64
27 Heterogeneity of the mutation rates of influenza A viruses: isolation of mutator mutants. J Virol 1992 1.61
28 Nuclear transport of influenza virus polymerase PA protein. Virus Res 1992 1.59
29 Three-dimensional reconstruction of a recombinant influenza virus ribonucleoprotein particle. EMBO Rep 2001 1.55
30 Fixation of mutations in the viral genome during an outbreak of foot-and-mouth disease: heterogeneity and rate variations. Gene 1986 1.53
31 Characterization of influenza virus PB1 protein binding to viral RNA: two separate regions of the protein contribute to the interaction domain. J Virol 1999 1.52
32 Phenotypic hiding: the carryover of mutations in RNA viruses as shown by detection of mar mutants in influenza virus. J Virol 1989 1.50
33 Molecular cloning and sequencing of influenza virus A/Victoria/3/75 polymerase genes: sequence evolution and prediction of possible functional domains. Virus Res 1989 1.49
34 pac gene as efficient dominant marker and reporter gene in mammalian cells. Methods Enzymol 1992 1.48
35 The N-terminal half of the influenza virus NS1 protein is sufficient for nuclear retention of mRNA and enhancement of viral mRNA translation. Nucleic Acids Res 1997 1.48
36 Mutational analysis of influenza A virus nucleoprotein: identification of mutations that affect RNA replication. J Virol 1999 1.47
37 Lung histopathological findings in fatal pandemic influenza A (H1N1). Med Intensiva 2011 1.46
38 Mutational analysis of the influenza virus A/Victoria/3/75 PA protein: studies of interaction with PB1 protein and identification of a dominant negative mutant. J Gen Virol 1996 1.43
39 Mutational analysis identifies functional domains in the influenza A virus PB2 polymerase subunit. J Virol 1996 1.38
40 The PA influenza virus polymerase subunit is a phosphorylated protein. J Gen Virol 1998 1.33
41 Interaction of influenza virus NS1 protein and the human homologue of Staufen in vivo and in vitro. Nucleic Acids Res 1999 1.32
42 Regulated M1 mRNA splicing in influenza virus-infected cells. J Gen Virol 1991 1.28
43 Replication of orthomyxoviruses. Adv Virus Res 1999 1.27
44 In vitro reconstitution of active influenza virus ribonucleoprotein complexes using viral proteins purified from infected cells. J Gen Virol 1992 1.26
45 The synthesis of influenza virus negative-strand RNA takes place in insoluble complexes present in the nuclear matrix fraction. Virus Res 1990 1.24
46 Degradation of cellular mRNA during influenza virus infection: its possible role in protein synthesis shutoff. J Gen Virol 1992 1.19
47 Influenza virus NS1 protein alters the subnuclear localization of cellular splicing components. J Gen Virol 1995 1.18
48 In vitro synthesis of full-length influenza virus complementary RNA. EMBO J 1985 1.13
49 Cross-links in African swine fever virus DNA. J Virol 1979 1.10
50 Sequence of the viral replicase gene from foot-and-mouth disease virus C1-Santa Pau (C-S8). Gene 1985 1.10
51 Open reading frame 5 of porcine reproductive and respiratory syndrome virus as a cause of virus-induced apoptosis. J Virol 1996 1.09
52 Epitope mapping of cross-reactive monoclonal antibodies specific for the influenza A virus PA and PB2 polypeptides. Virus Res 1995 1.08
53 Splicing of influenza virus matrix protein mRNA expressed from a simian virus 40 recombinant. J Gen Virol 1993 1.02
54 Protein synthesis shut-off induced by influenza virus infection is independent of PKR activity. J Virol 2000 1.00
55 Inhibition of African swine fever (ASF virus replication by phosphonoacetic acid. J Gen Virol 1978 1.00
56 In vivo reconstitution of active Thogoto virus polymerase: assays for the compatibility with other orthomyxovirus core proteins and template RNAs. Virus Res 1998 0.99
57 Evolution of the influenza virus neuraminidase gene during drift of the N2 subtype. Virology 1983 0.99
58 Molecular cloning of cDNA from foot-and-mouth disease virus C1-Santa Pau (C-S8). Sequence of protein-VP1-coding segment. Gene 1983 0.98
59 A primer vector system that allows temperature dependent gene amplification and expression in mammalian cells: regulation of the influenza virus NS1 gene expression. Nucleic Acids Res 1985 0.98
60 Oriented synthesis and cloning of influenza virus nucleoprotein cDNA that leads to its expression in mammalian cells. Virus Res 1985 0.98
61 Construction of cell lines that regulate by temperature the amplification and expression of influenza virus non-structural protein genes. EMBO J 1986 0.92
62 Regulation of gene amplification and expression in cells that constitutively express a temperature sensitive SV40 T-antigen. Nucleic Acids Res 1985 0.91
63 Cleavage of p220 by purified poliovirus 2A(pro) in cell-free systems: effects on translation of capped and uncapped mRNAs. Biochemistry 1997 0.91
64 Heterogeneity among influenza H3N2 isolates recovered during an outbreak. Brief report. Arch Virol 1985 0.90
65 An estimation of the nucleotide substitution rate at defined positions in the influenza virus haemagglutinin gene. J Gen Virol 1994 0.89
66 Plasmid vectors based on Tn10 DNA: gene expression regulated by tetracycline. Plasmid 1984 0.84
67 Anomalous roughening of viscous fluid fronts in spontaneous imbibition. Phys Rev Lett 2005 0.83
68 Permanent cell lines established from ts-COS cells that regulate by temperature the amplification and expression of cloned genes. Nucleic Acids Res 1987 0.81
69 Pressure-dependent scaling scenarios in experiments of spontaneous imbibition. Phys Rev E Stat Nonlin Soft Matter Phys 2007 0.79
70 Transfection of MDCK cells with influenza virus ribonucleoprotein complexes. Microbiologia 1988 0.79
71 Nonlinear Saffman-Taylor instability. Phys Rev Lett 2004 0.78
72 Relevance of dynamic wetting in viscous fingering patterns. Phys Rev E Stat Nonlin Soft Matter Phys 2006 0.77
73 Instabilities in the oscillatory flow of a complex fluid. Phys Rev E Stat Nonlin Soft Matter Phys 2007 0.77
74 Permanent cell lines that show temperature-dependent expression of adenovirus virus-associated RNA. J Virol 1989 0.75
75 [Rhabdomyolysis after treatment with atorvastatin detected by bone scintigraphy]. Rev Esp Med Nucl 2006 0.75
76 Pattern formation and interface pinch-off in rotating Hele-Shaw flows: a phase-field approach. Phys Rev E Stat Nonlin Soft Matter Phys 2009 0.75
77 Systematic weakly nonlinear analysis of interfacial instabilities in Hele-Shaw flows. Phys Rev E Stat Nonlin Soft Matter Phys 2001 0.75
78 [The utility of interictal SPECT in temporal lobe epilepsy]. Neurologia 2006 0.75
79 Fluctuations in Saffman-Taylor fingers with quenched disorder. Phys Rev E Stat Nonlin Soft Matter Phys 2006 0.75
80 Experiments of periodic forcing of Saffman-Taylor fingers. Phys Rev E Stat Nonlin Soft Matter Phys 2008 0.75
81 Measurements of the bulk and interfacial velocity profiles in oscillating Newtonian and Maxwellian fluids. Phys Rev E Stat Nonlin Soft Matter Phys 2005 0.75
82 Systematic weakly nonlinear analysis of radial viscous fingering. Phys Rev E Stat Nonlin Soft Matter Phys 2003 0.75
83 [Ovarian and para-aortic recurrence from cervix cancer detected by PET/CT]. Rev Esp Med Nucl 2006 0.75
84 Anomalous roughening of Hele-Shaw flows with quenched disorder. Phys Rev Lett 2002 0.75
85 [Different samarium-153 behavior in bone metastases and arthrosis in a case of breast cancer and painful bones]. Rev Esp Med Nucl 2005 0.75
86 [Psoas abscess as cause of lumbar spine pain detected by scintigraphy with gallium in a patient with suspicion of spondylodiscitis]. Rev Esp Med Nucl 2004 0.75